| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuling Wu, Dongjun Xie, Qian Zheng, Shuang Peng, Ying Liu, Pengfei Ma, Lan Ye, Xiangang Mo, Zhanhui Fen. Downregulation of NHE1 expression attenuates apoptosis of primary hippocampal neurons of an epilepsy model through the calpain-1 pathway. Neuroscience letters. 2023-09-25. PMID:37748674. |
downregulation of nhe1 expression attenuates apoptosis of primary hippocampal neurons of an epilepsy model through the calpain-1 pathway. |
2023-09-25 |
2023-10-07 |
Not clear |
| Xing-Dong Chen, Jing-Xiang Wei, Hai-Yan Wang, Yu-Yuan Peng, Can Tang, Yang Ding, Sen Li, Zai-Yun Long, Xiu-Min Lu, Yong-Tang Wan. Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats. Neuropharmacology. 2023-09-24. PMID:37742716. |
it was observed that sal protected against hippocampal neuronal apoptosis in ptsd rats by reducing the number of tunel-positive cells and modulating apoptosis-related proteins (bcl-2 and bax). |
2023-09-24 |
2023-10-07 |
rat |
| Xing-Dong Chen, Jing-Xiang Wei, Hai-Yan Wang, Yu-Yuan Peng, Can Tang, Yang Ding, Sen Li, Zai-Yun Long, Xiu-Min Lu, Yong-Tang Wan. Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats. Neuropharmacology. 2023-09-24. PMID:37742716. |
in conclusion, our results demonstrated that sal could attenuate sps-induced ptsd-like behaviors by inhibiting hippocampal neuronal apoptosis, enhancing hippocampal synaptic plasticity, and reducing neuroinflammatory responses. |
2023-09-24 |
2023-10-07 |
rat |
| Guoqing Wu, Yanyan W. Neuroprotective effect of Kurarinone against corticosterone-induced cytotoxicity on rat hippocampal neurons by targeting BACE1 to activate P13K-AKT signaling - A potential treatment in insomnia disorder. Pharmacology research & perspectives. vol 11. issue 5. 2023-09-23. PMID:37740616. |
the effect of kur on hippocampal neuronal cell (hnc) viability and apoptosis were assessed by cell counting kit-8 (cck-8) assay and flow cytometry, respectively. |
2023-09-23 |
2023-10-07 |
rat |
| Seyed Khalil Rashidi, Ata Kalirad, Shahram Rafie, Ebrahim Behzad, Mitra Ansari Dezfoul. The role of microRNAs in neurobiology and pathophysiology of the hippocampus. Frontiers in molecular neuroscience. vol 16. 2023-09-20. PMID:37727513. |
there is strong evidence that abnormalities in mirnas are contributed in neurodegenerative mechanisms in the hippocampus through imbalanced activity of ion channels, neuronal excitability, synaptic plasticity and neuronal apoptosis. |
2023-09-20 |
2023-10-07 |
Not clear |
| Xiao Wu, Xiaona Zhang, Lulu Sun, Xiaoming Lu, Cunsi She. Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 7. 2023-09-16. PMID:37715385. |
in this study, we investigated whether and how ica can prevent cums-induced depression-like behaviors in rats by modulating hippocampus neuronal apoptosis. |
2023-09-16 |
2023-10-07 |
rat |
| Xiao Wu, Xiaona Zhang, Lulu Sun, Xiaoming Lu, Cunsi She. Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 7. 2023-09-16. PMID:37715385. |
in conclusion, our research provides new evidence to understand the anti-depressant activity of ica, which relates to its inhibition of neuronal apoptosis in the hippocampus through the mitochondrial apoptotic pathway. |
2023-09-16 |
2023-10-07 |
rat |
| Khadga Raj Aran, G D Gupta, Shamsher Sing. Cladribine Induces Apoptosis, Neuroinflammation, Mitochondrial Oxidative Stress, Tau Phosphorylation and Aβ (1-42) Pathway in the Hippocampus: An In vivo Approach. Journal of chemical neuroanatomy. 2023-09-14. PMID:37708945. |
cladribine induces apoptosis, neuroinflammation, mitochondrial oxidative stress, tau phosphorylation and aβ (1-42) pathway in the hippocampus: an in vivo approach. |
2023-09-14 |
2023-10-07 |
rat |
| Qin Yuan, Li Sun, Gangguo Ma, Huanjun Shen, Shuang Wang, Fei Guo, Xude Sun, Changjun Ga. Alterations of the gut microbial community structure modulates the Th17 cells response in a rat model of asphyxial cardiac arrest. Biochemistry and biophysics reports. vol 35. 2023-09-13. PMID:37701737. |
furthermore, fecal microbiota transplantation (fmt) from rats with ca/cpr induced th17 cell response, promoting hippocampal cell apoptosis and declining learning ability and memory in recipient rats. |
2023-09-13 |
2023-10-07 |
rat |
| Jiaqi Yuan, Mengjie He, Xueling Dai, Qing Huo, Ping Chang, Jing Zhang, Shuo Wang, Yaxuan Su. The beneficial effect of 3,6'-Disinapoyl sucrose on the cognitive decline via CREB/BDNF signal pathway in APP/PS1 transgenic mice. Journal of neurophysiology. 2023-09-13. PMID:37702542. |
morphological alterations of hippocampus neurons were observed by nissl staining and neuronal of apoptosis were assessed by tunel assay. |
2023-09-13 |
2023-10-07 |
mouse |
| Jiaqi Yuan, Mengjie He, Xueling Dai, Qing Huo, Ping Chang, Jing Zhang, Shuo Wang, Yaxuan Su. The beneficial effect of 3,6'-Disinapoyl sucrose on the cognitive decline via CREB/BDNF signal pathway in APP/PS1 transgenic mice. Journal of neurophysiology. 2023-09-13. PMID:37702542. |
diss significantly ameliorated the cognitive disorder in app/ps1 transgenic mice, reduced apoptosis by decreasing the ratio of bax/bcl-2 in hippocampal neurons, and restored the abnormal secretion of inflammatory factors (il-2, tnf-α, il-1β, and il-6). |
2023-09-13 |
2023-10-07 |
mouse |
| Siming Huo, Xuliang Zhang, Jinyu Xu, Jian Zhang, Jiayu Du, Bo Li, Miao Song, Bing Shao, Yanfei Li, Feibo X. Parkin-mediated mitophagy protects against aluminum trichloride-induced hippocampal apoptosis in mice via the mtROS-NLRP3 pathway. Ecotoxicology and environmental safety. vol 264. 2023-09-13. PMID:37703808. |
parkin-mediated mitophagy protects against aluminum trichloride-induced hippocampal apoptosis in mice via the mtros-nlrp3 pathway. |
2023-09-13 |
2023-10-07 |
mouse |
| Ying Lv, Xuegang Zhao, Rui Zhang, Zhaopeng He, Yanfeng Xu, Lihong Tu, Lei Jiang, Shunjiang Xu, Qingfu Zhan. Oxidative stress mediates hippocampal neuronal apoptosis through ROS/JNK/P53 pathway in rats with PTSD triggered by high-voltage electrical burn. Folia morphologica. 2023-09-11. PMID:37691512. |
oxidative stress mediates hippocampal neuronal apoptosis through ros/jnk/p53 pathway in rats with ptsd triggered by high-voltage electrical burn. |
2023-09-11 |
2023-10-07 |
rat |
| Ying Lv, Xuegang Zhao, Rui Zhang, Zhaopeng He, Yanfeng Xu, Lihong Tu, Lei Jiang, Shunjiang Xu, Qingfu Zhan. Oxidative stress mediates hippocampal neuronal apoptosis through ROS/JNK/P53 pathway in rats with PTSD triggered by high-voltage electrical burn. Folia morphologica. 2023-09-11. PMID:37691512. |
the purpose of this study is to investigate the underlying mechanism of oxidative stress mediates hippocampal neuronal apoptosis in rats with ptsd triggered by hveb. |
2023-09-11 |
2023-10-07 |
rat |
| Yi-Bo Xu, Yang Sun, Lin-Yu Xiao, Guo-Qing Zhu, Xue Song, Jian-Guo Hu, Qi Q. [Effect of Shionone on Neuron Apoptosis After Spinal Cord Injury in Mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023-09-07. PMID:37674468. |
methods c57bl/6 mice were treated to induce the sci model and then assigned into a model group(sci group),a sci+shi group,and a sham surgery(control)group.the basso mouse scale(bms)score was determined to evaluate the recovery of motor function in sci mice.hematoxylin-eosin(he)staining,nissl staining,and immunofluorescence staining were employed to examine the fibrosis,morphological changes of neurons,and neuron apoptosis in the spinal cord tissue of sci mice,respectively.the mouse hippocampal neuronal cell line ht22 was cultured in vitro and then classified into tumor necrosis factor α(tnf-α)induction and shi groups.western blotting was employed to determine the expression of apoptosis-associated proteins.network pharmacology,gene ontology annotation,and kyoto encyclopedia of genes and genomes pathway enrichment were employed to predict the possible molecular targets and signaling pathways of shi in promoting functional recovery from sci.furthermore,the prediction results were verified by in vitro and in vivo experiments. |
2023-09-07 |
2023-10-07 |
mouse |
| Julie Areias, Chrystelle Sola, Yan Chastagnier, Julien Pico, Nathalie Bouquier, Christophe Dadure, Julie Perroy, Vivien Szab. Whole-brain characterization of apoptosis after sevoflurane anesthesia reveals neuronal cell death patterns in the mouse neonatal neocortex. Scientific reports. vol 13. issue 1. 2023-09-07. PMID:37679476. |
the unbiased anatomical mapping used here allowed us to confirm sevoflurane-induced apoptosis in the perinatal period, neocortical involvement, and indicated striatal and metencephalic damage while suggesting moderate hippocampal one. |
2023-09-07 |
2023-10-07 |
mouse |
| Luwen Zhang, Wenjuan Tang, Yinan Ouyang, Miao Zhang, Ruirui Li, Lianping Sun, Chao Liu, Hailing Y. N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype. European journal of pharmacology. 2023-09-06. PMID:37673363. |
in conclusion, the therapeutic potential of pea for depressive mood disorders may be through targeting the hippocampal neuroplasticity, including increasing adult neurogenesis and synaptic plasticity, as well as down-regulated neuronal apoptosis, to remodel hippocampal circuitries upon functional integration and pparα pathway may be involved in this process. |
2023-09-06 |
2023-10-07 |
rat |
| Taotao Lu, Linlin Ding, Xiaoqing Zheng, Yongxu Li, Wei Wei, Weilin Liu, Jing Tao, Xiehua Xu. Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway. Molecular neurobiology. 2023-09-02. PMID:37659035. |
we also demonstrated that aa attenuated microglial activation by targeting the sirt3-nf-κb/mapk pathway and ameliorated microglial activation-induced tight junction degeneration in endothelial cells and apoptosis in hippocampal neurons. |
2023-09-02 |
2023-09-07 |
mouse |
| Sina Nikbin, Gita Fardad, Sara Yazdi, Marzieh Hosseini Bahman, Parvaneh Ettefagh, Sepideh Khalegi, Mino Molaei, Kamal Azizbeigi, Myriam Guerra-Balic, Joel Montané Mogas, Mehdi Zargani, Mohammad Ali Azarbayjan. Aerobic exercise training reduces deep-frying oil-induced apoptosis of hippocampal tissue by reducing oxidative stress in male rats. Journal of chemical neuroanatomy. 2023-08-31. PMID:37652270. |
aerobic exercise training reduces deep-frying oil-induced apoptosis of hippocampal tissue by reducing oxidative stress in male rats. |
2023-08-31 |
2023-09-07 |
rat |
| Sina Nikbin, Gita Fardad, Sara Yazdi, Marzieh Hosseini Bahman, Parvaneh Ettefagh, Sepideh Khalegi, Mino Molaei, Kamal Azizbeigi, Myriam Guerra-Balic, Joel Montané Mogas, Mehdi Zargani, Mohammad Ali Azarbayjan. Aerobic exercise training reduces deep-frying oil-induced apoptosis of hippocampal tissue by reducing oxidative stress in male rats. Journal of chemical neuroanatomy. 2023-08-31. PMID:37652270. |
since moderate-intensity aerobic exercise training (at) reduces os, the current search investigated the effects of at on os, apoptosis, and neurogenesis markers in the hippocampal tissue of dfo-fed rats. |
2023-08-31 |
2023-09-07 |
rat |