| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Wang, Hui Hu, Yuhan Wu, Yun Zhao, Fang Xie, Zhaowei Sun, Xue Wang, Lingjia Qia. Norepinephrine Promotes Neuronal Apoptosis of Hippocampal HT22 Cells by Up-regulating the Expression of Long Non-coding RNA MALAT1. Stress (Amsterdam, Netherlands). 2023-08-26. PMID:37632346. |
the data showed that the rate of apoptosis rate and the levels of apoptotic proteins (cleaved-caspase3 and cleaved-parp) were significantly increased in ht22 cells after a high dose of ne treatment, suggesting a facilitative role of ne on hippocampal neuronal apoptosis. |
2023-08-26 |
2023-09-07 |
Not clear |
| Ying Wang, Hui Hu, Yuhan Wu, Yun Zhao, Fang Xie, Zhaowei Sun, Xue Wang, Lingjia Qia. Norepinephrine Promotes Neuronal Apoptosis of Hippocampal HT22 Cells by Up-regulating the Expression of Long Non-coding RNA MALAT1. Stress (Amsterdam, Netherlands). 2023-08-26. PMID:37632346. |
in conclusion, high level of the stress-induced hormone ne promoted apoptosis of hippocampal neurons through elevating the expression of malat1. |
2023-08-26 |
2023-09-07 |
Not clear |
| Hasan Kilicdag, Kubra Akillioglu, Emine Kilic Bagır, Seda Kose, Seyda Erdoga. Neuroserpin as an adjuvant therapy for hypothermia on brain injury in neonatal hypoxic-ischemic rats. American journal of perinatology. 2023-08-23. PMID:37611639. |
apoptosis was detected by caspase-3 activity and terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling (tunel) staining and was counted in the hippocampus. |
2023-08-23 |
2023-09-07 |
human |
| Jinxia Zhai, Chao Wang, Liang Jin, Fangtao Liu, Yinzhu Xiao, Hongfeng Gu, Mingjie Liu, Yongjun Che. Gut Microbiota Metabolites Mediate Bax to Reduce Neuronal Apoptosis via cGAS/STING Axis in Epilepsy. Molecular neurobiology. 2023-08-21. PMID:37605097. |
the reduction of bax protein attenuated the hippocampal neuron cell apoptosis in ptz-induced ep and ep progression. |
2023-08-21 |
2023-09-07 |
mouse |
| Salinee Naewla, Ram Prajit, Nataya Sritawan, Kornrawee Suwannakot, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmore, Jariya Umka Welba. Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-19. PMID:37597319. |
hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats. |
2023-08-19 |
2023-09-07 |
rat |
| Salinee Naewla, Ram Prajit, Nataya Sritawan, Kornrawee Suwannakot, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmore, Jariya Umka Welba. Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-19. PMID:37597319. |
this study investigated whether hsd could attenuate impairments of hippocampal neural stem cells related to apoptosis induced by mtx. |
2023-08-19 |
2023-09-07 |
rat |
| Salinee Naewla, Ram Prajit, Nataya Sritawan, Kornrawee Suwannakot, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmore, Jariya Umka Welba. Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-19. PMID:37597319. |
these results confirm that hsd can ameliorate mtx-induced impairments of hippocampal nsc proliferation and neuronal apoptosis. |
2023-08-19 |
2023-09-07 |
rat |
| - Baiyu Li, - Shuyan Liu, - Taowen Ren, - BoYangYa. Effects of curcumin on memory, hippocampal acetylcholine level and neuroapoptosis in repeated cerebral ischemia rat model. Pakistan journal of pharmaceutical sciences. vol 36. issue 3. 2023-08-15. PMID:37580934. |
the aim of this study was to determine the protective effects of curcumin on memory, hippocampal acetylcholine level and apoptosis in a rat model of repeated cerebral ischemia. |
2023-08-15 |
2023-09-07 |
rat |
| - Baiyu Li, - Shuyan Liu, - Taowen Ren, - BoYangYa. Effects of curcumin on memory, hippocampal acetylcholine level and neuroapoptosis in repeated cerebral ischemia rat model. Pakistan journal of pharmaceutical sciences. vol 36. issue 3. 2023-08-15. PMID:37580934. |
memory function was evaluated by eight-arm radial maze task and morris water maze (mwm) test, acetylcholine release (ach) in the dorsal hippocampus was evaluated by microdialysis-hplc) and neuron apoptosis was investigated by terminal deoxynucleotidyltransferase mediated fluorescein-deoxyuridine triphosphate nick-end labeling. |
2023-08-15 |
2023-09-07 |
rat |
| - Baiyu Li, - Shuyan Liu, - Taowen Ren, - BoYangYa. Effects of curcumin on memory, hippocampal acetylcholine level and neuroapoptosis in repeated cerebral ischemia rat model. Pakistan journal of pharmaceutical sciences. vol 36. issue 3. 2023-08-15. PMID:37580934. |
4voi test reviled impaired memory, reduced dorsal hippocampus ach level and induced apoptosis in the repeated cerebral ischemia rat model. |
2023-08-15 |
2023-09-07 |
rat |
| - Baiyu Li, - Shuyan Liu, - Taowen Ren, - BoYangYa. Effects of curcumin on memory, hippocampal acetylcholine level and neuroapoptosis in repeated cerebral ischemia rat model. Pakistan journal of pharmaceutical sciences. vol 36. issue 3. 2023-08-15. PMID:37580934. |
curcumin significantly improved the memory deficit (p<0.001), increased ach level (p<0.001) and prevented hippocampal neuron apoptosis (p<0.001). |
2023-08-15 |
2023-09-07 |
rat |
| Yuanlu Huang, Yuxuan Yang, Changsheng Ye, Ziye Liu, Fusheng We. The m Neurochemical research. 2023-08-12. PMID:37572160. |
hippocampal neuronal viability and apoptosis were measured by mtt assay and flow cytometry, respectively. |
2023-08-12 |
2023-08-16 |
rat |
| Hongmei Wu, Dongyu Min, Buxun Sun, Yifan Ma, Hongpeng Chen, Jing Wu, Ping Ren, Jiabi Wu, Yonggang Cao, Baoshan Zhao, Peng Wan. Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats. Environmental science and pollution research international. 2023-08-10. PMID:37561300. |
also, levels of proteins involved in apoptosis were analyzed histologically in the hippocampus in response to oxidative stress. |
2023-08-10 |
2023-08-16 |
rat |
| Cancan You, Zilong Zhang, Huiya Ying, Zijing Yang, Yixuan Ma, Jingyi Hong, Mingjie Xue, Xuan Li, Huimin Li, Chengrui Zhang, Wei Wang, Xiaohong Cai, Xiucui L. Blockage of calcium-sensing receptor improves chronic intermittent hypoxia-induced cognitive impairment by PERK-ATF4-CHOP pathway. Experimental neurology. 2023-08-08. PMID:37553048. |
besides, treatment of casr inhibitor alleviated the hippocampal neuronal apoptosis following cih with downregulated p-perk, atf4 and chop, suggesting that casr contributed to cih-induced neuronal apoptosis in hippocampus via ers pathway. |
2023-08-08 |
2023-08-16 |
mouse |
| Cancan You, Zilong Zhang, Huiya Ying, Zijing Yang, Yixuan Ma, Jingyi Hong, Mingjie Xue, Xuan Li, Huimin Li, Chengrui Zhang, Wei Wang, Xiaohong Cai, Xiucui L. Blockage of calcium-sensing receptor improves chronic intermittent hypoxia-induced cognitive impairment by PERK-ATF4-CHOP pathway. Experimental neurology. 2023-08-08. PMID:37553048. |
sum up, our results demonstrated that casr accelerated hippocampal apoptosis via perk-atf4-chop pathway, holding a critical function on cih-mediated cognitive impairment. |
2023-08-08 |
2023-08-16 |
mouse |
| Weiren Xiao, Shouren Chen, Jinzhuan Chen, Jianzhong Huan. Dexmedetomidine alleviates propofol-induced neural injury in developing rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-08-07. PMID:37550504. |
dexmedetomidine reduced propofol-induced cell apoptosis in the hippocampus and modulated the mrna expression of bcl-2 and bax. |
2023-08-07 |
2023-08-14 |
rat |
| An-Rong Wang, Lian-Fang Mi, Zhi-Lei Zhang, Ming-Zhe Hu, Ze-Yu Zhao, Bin Liu, Yan-Bin Li, Shu Zhen. Corrigendum to "Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway" Behav. Brain Res. 403 (2021) 113138; pubmed: 33493495. Behavioural brain research. 2023-08-06. PMID:37544824. |
corrigendum to "saikosaponin a improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-creb/bdnf pathway" behav. |
2023-08-06 |
2023-08-14 |
Not clear |
| Xueying Zhang, Rui Gao, Changteng Zhang, Yi Teng, Hai Chen, Qi Li, Changliang Liu, Jiahui Wu, Liuxing Wei, Liyun Deng, Lining Wu, Shixin Ye-Lehmann, Xiaobo Mao, Jin Liu, Tao Zhu, Chan Che. Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice. Signal transduction and targeted therapy. vol 8. issue 1. 2023-08-06. PMID:37544956. |
importantly, compared to the wild-type (wt) mice, tlr3 knockout (ko) mice and tlr3-specific neuronal knockdown mice both displayed improved cognitive function, reduced levels of inflammatory cytokines and neuronal apoptosis and attenuated injury to hippocampal neuroplasticity. |
2023-08-06 |
2023-08-14 |
mouse |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Shuang Peng, Xuling Wu, Qian Zheng, Jianwei Xu, Dongjun Xie, Mengyun Zhou, Mingwei Wang, Yongran Cheng, Lan Ye, Xiangang Mo, Zhanhui Fen. Downregulating NHE-1 decreases the apoptosis of hippocampal cells in epileptic model rats based on the NHE-1/calpain1 pathway. Heliyon. vol 9. issue 7. 2023-08-04. PMID:37539113. |
downregulating nhe-1 decreases the apoptosis of hippocampal cells in epileptic model rats based on the nhe-1/calpain1 pathway. |
2023-08-04 |
2023-08-14 |
rat |