| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinyu Yao, Xiaoyi Xu, Kunhua Hu, Zhaoshou Yang, Shaodong Den. BANF1 promotes glutamate-induced apoptosis of HT-22 hippocampal neurons. Molecular biology reports. 2023-10-14. PMID:37838622. |
banf1 promotes glutamate-induced apoptosis of ht-22 hippocampal neurons. |
2023-10-14 |
2023-11-08 |
mouse |
| Candela Zorzo, Lucía Solares, Marta Mendez, Magdalena Mendez-Lope. Hippocampal alterations after SARS-CoV-2 infection: A systematic review. Behavioural brain research. vol 455. 2023-10-06. PMID:37703951. |
hippocampal human postmortem and animal studies observed alterations in neurogenesis, dendrites, and immune response, besides high apoptosis and neuroinflammation. |
2023-10-06 |
2023-10-15 |
human |
| Zan Zhou, Wen-Jun Jiang, Li Li, Jun-Qiang S. Noise exposure increase apoptosis in the hippocampus of AD mice through the upregulation of CTSS. Biochemical and biophysical research communications. vol 681. 2023-10-06. PMID:37801777. |
noise exposure increase apoptosis in the hippocampus of ad mice through the upregulation of ctss. |
2023-10-06 |
2023-10-15 |
mouse |
| Zan Zhou, Wen-Jun Jiang, Li Li, Jun-Qiang S. Noise exposure increase apoptosis in the hippocampus of AD mice through the upregulation of CTSS. Biochemical and biophysical research communications. vol 681. 2023-10-06. PMID:37801777. |
based on these findings, we hypothesize that noise exposure potentially heightens apoptosis within the hippocampus through upregulating ctss expression, subsequently posing a threat to ad model animals. |
2023-10-06 |
2023-10-15 |
mouse |
| Feng-Xiao Hao, Meng-Nan Zeng, Bing Cao, Xi-Wen Liang, Xin-Mian Jiao, Wei-Sheng Feng, Xiao-Ke Zhen. [Effect of aqueous extract of Corni Fructus on Aβ_(25-35)-induced brain injury and neuroinflammation in mice with Alzheimer's disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 15. 2023-10-06. PMID:37802769. |
flow cytometry was used to detect the apoptosis level of primary hippocampal cells in mice. |
2023-10-06 |
2023-10-15 |
mouse |
| Meng-Nan Zeng, Bing Cao, Ao-Zi Feng, Peng-Li Guo, Meng Liu, Yu-Han Zhang, Meng Li, Xiao-Ke Zhen. [Platycladi Semen oil ameliorates Aβ_(25-35)-induced brain injury in mice based on network pharmacology and gut microbiota]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 15. 2023-10-06. PMID:37802772. |
the results showed that sp could improve the learning and memory function of aβ_(25-35)-induced mice, reduce hippocampal neuronal damage, decrease the levels of aβ_(1-42)/aβ_(1-40), p-tau, and indicators related to apoptosis and oxidative stress in the brain, and maintain the homeostasis of immune cells and gm. |
2023-10-06 |
2023-10-15 |
mouse |
| Xiu Yang, Ke-Han Liao, Isaac B Deng, Lan-Chun Zhan. Knockdown of interleukin-6 plays a neuroprotective role against hypoxia-ischemia in neonatal rats via inhibition of caspase 3 and Bcl-2-associated X protein signaling pathway. Ibrain. vol 8. issue 3. 2023-10-03. PMID:37786746. |
the inhibition of il-6 expression fostered neuronal and axonal growth, and a reduction in cellular apoptosis in cortical neuronal cultures, and cortex and hippocampus of neonatal rats. |
2023-10-03 |
2023-10-07 |
rat |
| Bin Yang, Han-Yu Wen, Ri-Sheng Liang, Ting-Ming Lu, Zheng-Yan Zhu, Chun-Hua Wan. Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation. World journal of psychiatry. vol 13. issue 9. 2023-09-29. PMID:37771639. |
hippocampus protection from apoptosis by baicalin in a licl-pilocarpine-induced rat status epilepticus model through autophagy activation. |
2023-09-29 |
2023-10-07 |
rat |
| Hany H Arab, Ahmed H Eid, Rania Yahia, Shuruq E Alsufyani, Ahmed M Ashour, Azza A K El-Sheikh, Hany W Darwish, Muhammed A Saad, Muhammad Y Al-Shorbagy, Marwa A Masou. Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats. Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765022. |
in this study, topiramate was tested for its potential to combat the cognitive deficits induced by cadmium in rats with an emphasis on hippocampal oxidative insult, apoptosis, and autophagy. |
2023-09-28 |
2023-10-07 |
rat |
| Yang Liu, Wen Guo, Si-Lu Hon. Aerobic exercise mitigates hippocampal neuronal apoptosis by regulating DAPK1/CDKN2A/REDD1/FoXO1/FasL signaling pathway in D-galactose-induced aging mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 10. 2023-09-28. PMID:37768886. |
aerobic exercise mitigates hippocampal neuronal apoptosis by regulating dapk1/cdkn2a/redd1/foxo1/fasl signaling pathway in d-galactose-induced aging mice. |
2023-09-28 |
2023-10-07 |
mouse |
| Yang Liu, Wen Guo, Si-Lu Hon. Aerobic exercise mitigates hippocampal neuronal apoptosis by regulating DAPK1/CDKN2A/REDD1/FoXO1/FasL signaling pathway in D-galactose-induced aging mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 10. 2023-09-28. PMID:37768886. |
specifically, studies have found that exercise effectively inhibits hippocampal neuronal apoptosis, while the molecular mechanism remains unclear. |
2023-09-28 |
2023-10-07 |
mouse |
| Yang Liu, Wen Guo, Si-Lu Hon. Aerobic exercise mitigates hippocampal neuronal apoptosis by regulating DAPK1/CDKN2A/REDD1/FoXO1/FasL signaling pathway in D-galactose-induced aging mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 10. 2023-09-28. PMID:37768886. |
in the present study, we investigated the impact of aerobic exercise on hippocampal neuronal apoptosis in aging mice and the potential involvement of dapk1 and its downstream pathways based on recent data that dapk1 may be associated with neuronal death in neurodegenerative diseases. |
2023-09-28 |
2023-10-07 |
mouse |
| Yang Liu, Wen Guo, Si-Lu Hon. Aerobic exercise mitigates hippocampal neuronal apoptosis by regulating DAPK1/CDKN2A/REDD1/FoXO1/FasL signaling pathway in D-galactose-induced aging mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 10. 2023-09-28. PMID:37768886. |
following behavioral testing, hippocampal samples were examined histologically and biochemically to detect pathological changes, neuronal apoptosis, and mrna and protein levels. |
2023-09-28 |
2023-10-07 |
mouse |
| Jiahui Li, Caiyan Xue, Hongyan Yang, Jiaxin Zhang, Guohua Li, Jijun Li, Fang Kuang, Jing Chen, Shu Zhang, Feng Gao, Zhenzhen Kou, Xing Zhang, Ling Don. Simulated weightlessness induces hippocampal insulin resistance and cognitive impairment. Life sciences. 2023-09-27. PMID:37758017. |
in addition, 4 weeks of simulated weightlessness induced neuronal apoptosis and degeneration in the hippocampus, as evidenced by increased tunel and fluoro-jade b staining-positive neurons. |
2023-09-27 |
2023-10-07 |
rat |
| Jiahui Li, Caiyan Xue, Hongyan Yang, Jiaxin Zhang, Guohua Li, Jijun Li, Fang Kuang, Jing Chen, Shu Zhang, Feng Gao, Zhenzhen Kou, Xing Zhang, Ling Don. Simulated weightlessness induces hippocampal insulin resistance and cognitive impairment. Life sciences. 2023-09-27. PMID:37758017. |
these data suggest that long-term simulated weightlessness induces cognitive impairment as well as neuronal apoptosis and neural degeneration, partially through hippocampal insulin resistance via pten up-regulation. |
2023-09-27 |
2023-10-07 |
rat |
| Yue Ming, Zhihui Deng, Xianhua Tian, Yuerong Jia, Meng Ning, Shuhua Chen. Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism. Metabolic brain disease. 2023-09-26. PMID:37751122. |
this study primarily investigates the underlying mechanism of how the long non-coding rna malat1 affects neuronal apoptosis in the hippocampus of mice with autism spectrum disorder (asd). |
2023-09-26 |
2023-10-07 |
mouse |
| Yue Ming, Zhihui Deng, Xianhua Tian, Yuerong Jia, Meng Ning, Shuhua Chen. Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism. Metabolic brain disease. 2023-09-26. PMID:37751122. |
consequently, these results further confirm the role of malat1 in suppressing neuronal apoptosis in the hippocampus of mice with asd through the regulation of casp3 promoter methylation. |
2023-09-26 |
2023-10-07 |
mouse |
| Xuling Wu, Dongjun Xie, Qian Zheng, Shuang Peng, Ying Liu, Pengfei Ma, Lan Ye, Xiangang Mo, Zhanhui Fen. Downregulation of NHE1 expression attenuates apoptosis of primary hippocampal neurons of an epilepsy model through the calpain-1 pathway. Neuroscience letters. 2023-09-25. PMID:37748674. |
downregulation of nhe1 expression attenuates apoptosis of primary hippocampal neurons of an epilepsy model through the calpain-1 pathway. |
2023-09-25 |
2023-10-07 |
Not clear |
| Xing-Dong Chen, Jing-Xiang Wei, Hai-Yan Wang, Yu-Yuan Peng, Can Tang, Yang Ding, Sen Li, Zai-Yun Long, Xiu-Min Lu, Yong-Tang Wan. Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats. Neuropharmacology. 2023-09-24. PMID:37742716. |
it was observed that sal protected against hippocampal neuronal apoptosis in ptsd rats by reducing the number of tunel-positive cells and modulating apoptosis-related proteins (bcl-2 and bax). |
2023-09-24 |
2023-10-07 |
rat |
| Xing-Dong Chen, Jing-Xiang Wei, Hai-Yan Wang, Yu-Yuan Peng, Can Tang, Yang Ding, Sen Li, Zai-Yun Long, Xiu-Min Lu, Yong-Tang Wan. Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats. Neuropharmacology. 2023-09-24. PMID:37742716. |
in conclusion, our results demonstrated that sal could attenuate sps-induced ptsd-like behaviors by inhibiting hippocampal neuronal apoptosis, enhancing hippocampal synaptic plasticity, and reducing neuroinflammatory responses. |
2023-09-24 |
2023-10-07 |
rat |