| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen Zhang, Yang Liu, Zhicun Wang, Shuyi He, Wenqi Liu, Yu Wu, Li Yang, Cheng Hu, Yunbing Wan. Remodeling brain pathological microenvironment to lessen cerebral ischemia injury by multifunctional injectable hydrogels. Journal of controlled release : official journal of the Controlled Release Society. 2024-04-06. PMID:38582336. |
the in vitro results exhibited the multifunctional hydrogel scavenged oxygen-glucose deprivation (ogd)-induced free radical, rescued the mitochondrial function, and maintained the survival and function of neurons, hence reducing neuronal apoptosis and neuroinflammation, consequently relieving ischemia injury in hippocampal neurons cell line (ht22). |
2024-04-06 |
2024-04-10 |
rat |
| Benjamin Ongnok, Nanthip Prathumsap, Titikorn Chunchai, Patcharapong Pantiya, Busarin Arunsak, Nipon Chattipakorn, Siriporn C Chattipakor. Nicotinic and Muscarinic Acetylcholine Receptor Agonists Counteract Cognitive Impairment in a Rat Model of Doxorubicin-Induced Chemobrain via Attenuation of Multiple Programmed Cell Death Pathways. Molecular neurobiology. 2024-04-03. PMID:38568417. |
dox insult also mediated hyperphosphorylation of tau and simultaneously induced various pcd, including apoptosis, necroptosis, and pyroptosis in the hippocampus. |
2024-04-03 |
2024-04-05 |
rat |
| Ming Wang, Binyuan Xu, Yangmei Xie, Ge Yao, Yinghui Che. Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis. Neurochemical research. 2024-03-30. PMID:38555337. |
he and tunel staining results showed that mir155hg knockdown suppressed the hippocampal neuron loss and apoptosis followed cse. |
2024-03-30 |
2024-04-02 |
rat |
| Beydolah Shahouzehi, Yaser Masoumi-Ardakani, Hossein Fallah, Soheil Aminizade. Evaluation of the effect of Exercise Trainings and CGRP receptor antagonist (BIBN 4096) on mitochondrial dynamic in the hippocampus of male Wistar rats. Neuroscience letters. 2024-03-29. PMID:38552868. |
the purpose of the present study is to evaluate the effect of six weeks of high-intensity interval training (hiit) and endurance training (et) with calcitonin gene-related peptide (cgrp) receptor antagonist on the expression of genes involved in mitochondrial dynamics and apoptosis in hippocampal tissue of male wistar rats. |
2024-03-29 |
2024-04-01 |
rat |
| Mubeen A Ansari, Aishah Al-Jarallah, Muddanna S Rao, Ahmed Babiker, Khaled Bensalama. Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer's disease. Brain research. 2024-03-29. PMID:38552936. |
upregulation of nadph-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: development of sporadic alzheimer's disease. |
2024-03-29 |
2024-04-01 |
rat |
| Paola Rodríguez-Quintero, Moisés Rubio-Osornio, Eric Uribe, Wilhelm Moreno, Luis A Marín-Castañeda, Zayra Morales, Alonso Portila, David Vázquez, Carmen Rubi. Exposure to Ozone Downregulates Bcl-2 and Increases Executing Caspases-3 and -8 in the Hippocampus, Frontal Cortex, and Cerebellum of Rats. Cureus. vol 16. issue 2. 2024-03-22. PMID:38516464. |
conclusions this study demonstrates that acute exposure to 1 ppm of ozone can trigger neuronal apoptosis in the frontal cortex, hippocampus, and cerebellum of rats, primarily through the activation of the extrinsic apoptosis pathway via caspase-8 and caspase-3. |
2024-03-22 |
2024-03-24 |
rat |
| Vaibhav Gupta, Rashmi Srivastav. Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica. Neurochemical research. 2024-03-20. PMID:38506951. |
ashwagandha diminishes hippocampal apoptosis induced by microwave radiation by acetylcholinesterase dependent neuro-inflammatory pathway in male coturnix coturnix japonica. |
2024-03-20 |
2024-03-23 |
cat |
| Vaibhav Gupta, Rashmi Srivastav. Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica. Neurochemical research. 2024-03-20. PMID:38506951. |
mwr also caused a significant decline in the nissil substances in the hippocampus region of brain indicating neurodegeneration through oxidative stress mediated hippocampal apoptosis. |
2024-03-20 |
2024-03-23 |
cat |
| Badrah Alghamdi, Emad H M Hassanein, Saif A Alharthy, Reem M Farsi, Steve Harake. Vinpocetine attenuates methotrexate-induced hippocampal intoxication via Keap-1/Nrf2, NF-κB/AP-1, and apoptotic pathways in rats. Drug and chemical toxicology. 2024-03-20. PMID:38508707. |
additionally, vnp attenuated apoptosis by reducing hippocampal bax levels while increasing bcl2 levels in mtx-intoxicated rats. |
2024-03-20 |
2024-03-23 |
rat |
| Badrah Alghamdi, Emad H M Hassanein, Saif A Alharthy, Reem M Farsi, Steve Harake. Vinpocetine attenuates methotrexate-induced hippocampal intoxication via Keap-1/Nrf2, NF-κB/AP-1, and apoptotic pathways in rats. Drug and chemical toxicology. 2024-03-20. PMID:38508707. |
in conclusion, our results suggested that vnp significantly attenuated mtx hippocampal intoxication by regulating keap-1/nrf2, nf-κb/ap-1, and apoptosis signaling in these effects. |
2024-03-20 |
2024-03-23 |
rat |
| Qian Deng, Jia-Qi Liang, Chen-Hui Gao, Xia Ge, Jin-Jin Zheng, Qing-Ping Zhan. Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats. Zhen ci yan jiu = Acupuncture research. vol 49. issue 3. 2024-03-19. PMID:38500323. |
effects of electroacupuncture on the pi3k/akt/creb signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats. |
2024-03-19 |
2024-03-21 |
rat |
| Qian Deng, Jia-Qi Liang, Chen-Hui Gao, Xia Ge, Jin-Jin Zheng, Qing-Ping Zhan. Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats. Zhen ci yan jiu = Acupuncture research. vol 49. issue 3. 2024-03-19. PMID:38500323. |
to observe the effects of electroacupuncture (ea) on the phosphatidylinositol-3-kinase (pi3k)/protein kinase b (akt)/camp response element binding protein (creb) signaling pathway-related proteins and hippocampal neuron apoptosis in diabetic cognitive impairment (dci) rats, and to explore the mechanisms of ea in treating dci. |
2024-03-19 |
2024-03-21 |
rat |
| Seyedeh Naghmeh Nourirad, Amhr-Hossein Bayat, Moitaba Sani, Amirreza Beirami, Maral Hasanzadeh, Susan Roustaee, Mobina Fathi, Kimia Vakili, Siavash Parvardeh, Gholam Hossein Meftahi, Nahid Sarahian, Fariba Khodagholi, Abbas Aliaghaei, Hojjat-Allah Abbaszadeh, Meysam Hassani Moghadda. Memory loss induced by lisdexamfetamine in the rat: A behavioral, electrophysiological, and histopathological Study. Behavioural brain research. 2024-03-18. PMID:38499158. |
also, in addition to an increase in expression of caspase-3 in the hippocampus, which indicates the susceptibility to apoptosis in ldx-treated rats, the number of microglia and astrocytes went up significantly in the ldx group. |
2024-03-18 |
2024-03-21 |
rat |
| Haoxuan Gao, Mi Tian, Xiaozhe Geng, Ji Zhao, Yanan Song, Bing Wu, Xueyan Tian, Yong Yang, Wensi Ni, Huifang Yan. Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring-Ca Ecotoxicology and environmental safety. vol 274. 2024-03-16. PMID:38492481. |
in conclusion, maternal cy exposure during pregnancy can cause neurobehavioral abnormalities and synaptic damage in offspring, which may be related to neuronal apoptosis induced by activation of the ip3r-grp75-vdac1 pathway in the hippocampus of offspring. |
2024-03-16 |
2024-03-19 |
Not clear |
| Jingyu Liu, Jikai Xu, Luan Jia, Yanjun Zhou, Qiang Fu, Yichen Wang, Danyang Mu, Dequan Wang, Ning Li, Yue Ho. Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer's disease. International journal of pharmaceutics. 2024-03-16. PMID:38492898. |
immunofluorescence analysis revealed that pterostilbene nanoemulsion was more potent in safeguarding hippocampal neurons and inhibiting apoptosis and oxidative stress than pterostilbene. |
2024-03-16 |
2024-03-19 |
Not clear |
| Jingjing Shao, Linlin Qu, Yao Liu, Jingjing Zhang, Yannan Liu, Jianjun Deng, Xiaoxuan Ma, Daidi Fa. Ginsenoside Rk3 Regulates Tryptophan Metabolism along the Brain-Gut Axis by Targeting Tryptophan Hydroxylase and Remodeling the Intestinal Microenvironment to Alleviate Depressive-Like Behavior in Mice. Journal of agricultural and food chemistry. 2024-03-15. PMID:38488514. |
additionally, rk3 improved the abnormal metabolism of tryptophan in brain tissue by targeting tryptophan hydroxylase, thereby reducing neuronal apoptosis and synaptic structural damage in the mouse hippocampus and prefrontal cortex. |
2024-03-15 |
2024-03-17 |
mouse |
| Yueying Liu, Jieru Chen, Meifang Jin, Zhenhong Li, Tian Tian, Lili Li, Hong N. Erratum: [Corrigendum] Relationship between changes in mitochondrial function and hippocampal neuronal apoptosis after recurrent convulsion during developmental stage. Experimental and therapeutic medicine. vol 27. issue 4. 2024-03-13. PMID:38476912. |
erratum: [corrigendum] relationship between changes in mitochondrial function and hippocampal neuronal apoptosis after recurrent convulsion during developmental stage. |
2024-03-13 |
2024-03-15 |
Not clear |
| Xuan Wang, Xiaole Tang, Pengfei Zhu, Dongyu Hua, Zheng Xie, Mingke Guo, Mengxin Que, Jing Yan, Xing Li, Qian Xia, Xiaoxiao Luo, Jiangjiang Bi, Yilin Zhao, Zhiqiang Zhou, Shiyong Li, Ailin Lu. CircAKT3 alleviates postoperative cognitive dysfunction by stabilizing the feedback cycle of miR-106a-5p/HDAC4/MEF2C axis in hippocampi of aged mice. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-03-13. PMID:38478029. |
according to the expression profiles, we observed that circakt3 was associated with hippocampal neuronal apoptosis in pocd mice. |
2024-03-13 |
2024-03-16 |
mouse |
| Hang Wang, Conghui Qiao, Yang Gao, Yiding Geng, Fengru Niu, Ruiming Yang, Zheng Wang, Wenbo Jiang, Hongru Su. The adverse effects of developmental exposure to polystyrene nanoparticles on cognitive function in weaning rats and the protective role of trihydroxy phenolacetone. Environmental pollution (Barking, Essex : 1987). 2024-03-09. PMID:38460594. |
furthermore, thp administration could significantly alleviate apoptosis induced by ps-np exposure in primary hippocampal cells through down-regulation of mapk3. |
2024-03-09 |
2024-03-12 |
rat |
| Sanika M Joshi, Nafisa M Jadavj. Deficiencies in one-carbon metabolism led to increased neurological disease risk and worse outcome: homocysteine is a marker of disease state. Frontiers in nutrition. vol 11. 2024-03-07. PMID:38450239. |
these studies have demonstrated the negative impacts of ultra-high levels of homocysteine can have on for example proliferation of neuroprogenitor cells in the adult hippocampus, as well as triggering neuronal apoptosis through a series of events, including dna damage, parp activation, nad depletion, mitochondrial dysfunction, and oxidative stress. |
2024-03-07 |
2024-03-09 |
human |