| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Moein Ebrahimi, Ali Dabbagh, Firoozeh Madad. Propofol-induced hippocampal Neurotoxicity: A mitochondrial perspective. Brain research. 2024-03-01. PMID:38428475. |
recent advances in molecular research have revealed that apoptosis, in close association with mitochondria, is a crucial mechanism through which propofol contributes to hippocampal toxicity. |
2024-03-01 |
2024-03-04 |
human |
| Kai Kang, Shu-Hui Chen, Da-Peng Wang, Feng Che. Inhibition of Endoplasmic Reticulum Stress Improves Chronic Ischemic Hippocampal Damage Associated with Suppression of IRE1α/TRAF2/ASK1/JNK-Dependent Apoptosis. Inflammation. 2024-02-24. PMID:38401021. |
inhibition of endoplasmic reticulum stress improves chronic ischemic hippocampal damage associated with suppression of ire1α/traf2/ask1/jnk-dependent apoptosis. |
2024-02-24 |
2024-02-27 |
mouse |
| Kai Kang, Shu-Hui Chen, Da-Peng Wang, Feng Che. Inhibition of Endoplasmic Reticulum Stress Improves Chronic Ischemic Hippocampal Damage Associated with Suppression of IRE1α/TRAF2/ASK1/JNK-Dependent Apoptosis. Inflammation. 2024-02-24. PMID:38401021. |
apoptosis of the hippocampus and ht22 cells was detected by tunel staining and annexin v-fitc analysis, respectively. |
2024-02-24 |
2024-02-27 |
mouse |
| Wenjing Yang, Chao Chen, Xiaolong Jiang, Yining Zhao, Junyang Wang, Qianqian Zhang, Jingyuan Zhang, Yan Feng, Shufang Cu. CACNA1B protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of Nrf2 after Cell biology international. 2024-02-23. PMID:38389270. |
cacna1b protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of nrf2 after although radiotherapy is the most effective treatment modality for brain tumors, it always injures the central nervous system, leading to potential sequelae such as cognitive dysfunction. |
2024-02-23 |
2024-02-25 |
rat |
| Qing Liu, Xiaoyan Ding, Ying Wang, Hairong Chu, Yan Guan, Meng Li, Kuisheng Su. Artemisinin reduces PTSD-like symptoms, improves synaptic plasticity, and inhibits apoptosis in rats subjected to single prolonged stress. Frontiers in pharmacology. vol 15. 2024-02-21. PMID:38379899. |
the apoptosis of hippocampal neurons was examined with western blot, tunel staining, and he staining. |
2024-02-21 |
2024-02-23 |
rat |
| Shuwei Wang, Aijun Liu, Chaopeng Xu, Jingxuan Hou, Jun Hon. GLP-1(7-36) protected against oxidative damage and neuronal apoptosis in the hippocampal CA region after traumatic brain injury by regulating ERK5/CREB. Molecular biology reports. vol 51. issue 1. 2024-02-20. PMID:38374452. |
glp-1(7-36) protected against oxidative damage and neuronal apoptosis in the hippocampal ca region after traumatic brain injury by regulating erk5/creb. |
2024-02-20 |
2024-02-22 |
Not clear |
| Rong Shao, Xiongchang Tan, Minfu Pan, Jiawen Huang, Liu Huang, Binyu Bi, Xiaohua Huang, Jie Wang, Xuebin L. Inulin alters gut microbiota to alleviate post-stroke depressive-like behavior associated with the IGF-1-mediated MAPK signaling pathway. Brain and behavior. vol 14. issue 1. 2024-02-20. PMID:38376033. |
psd is associated with increased hippocampal neuronal apoptosis and decreased synaptic connectivity. |
2024-02-20 |
2024-02-22 |
Not clear |
| Teng Zhang, Guodong Wan. Inhibition of RXRA-mediated PLA2G2A improves delirium in COPD mice by regulating endoplasmic reticulum stress pathway and inhibiting cell apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 1. 2024-02-19. PMID:38372090. |
tunel staining and he staining were used to analyze the apoptosis of mouse hippocampus cells. |
2024-02-19 |
2024-02-21 |
mouse |
| Yi-Ju Lee, Chang-Mao Lin, Yun-Ching Chang, Mon-Yuan Yang, Chau-Jong Wang, Li-Sung Hs. Nelumbo nucifera leaves extract ameliorated scopolamine-induced cognition impairment via enhanced adult hippocampus neurogenesis. Environmental toxicology. 2024-02-14. PMID:38351887. |
overall, our results revealed that n. nucifera leaf extracts and q3g promoted adult hippocampus neurogenesis and prevented apoptosis to mitigate scopolamine-induced cognition dysfunction through the regulation of bdnf signaling pathway. |
2024-02-14 |
2024-02-16 |
mouse |
| Kaina Xu, Zhanhong Liu, Shichao Pan, Na Zhang, Shuang Wu, Guangrun Yang, Xue Song, Ye Teng, Xu Ton. BMSCs attenuate radiation-induced brain injury induced hippocampal neuronal apoptosis through a PI3K/Akt/Bax/Bcl-2 signaling pathway. Brain research. 2024-02-08. PMID:38331376. |
bmscs attenuate radiation-induced brain injury induced hippocampal neuronal apoptosis through a pi3k/akt/bax/bcl-2 signaling pathway. |
2024-02-08 |
2024-02-11 |
Not clear |
| Siamak Sheikhi, Razieh Aghazadeh, Hojjat Sayyadi, Bagher Pourheydar, Ehsan Saboory, Morteza Bagheri, Leila Derafshpou. The effects of choline supplementation in mothers with hypothyroidism on the alteration of cognitive-behavioral, long-term potentiation, morphology, and apoptosis in the hippocampus of pre-pubertal offspring rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-02-08. PMID:38311365. |
the effects of choline supplementation in mothers with hypothyroidism on the alteration of cognitive-behavioral, long-term potentiation, morphology, and apoptosis in the hippocampus of pre-pubertal offspring rats. |
2024-02-08 |
2024-02-11 |
rat |
| Asmita Garg, Sanghamitra Bandyopadhya. Role of an interdependent Wnt, GSK3-β/β-catenin and HB-EGF/EGFR mechanism in arsenic-induced hippocampal neurotoxicity in adult mice. Chemosphere. 2024-02-07. PMID:38325618. |
further exploration of hippocampal neuronal survival and apoptosis demonstrated that treatment with rdkk1, licl, β-catenin and hb-egf improved nissl staining and neun levels, and reduced cleaved-caspase-3 levels in arsenic-treated mice. |
2024-02-07 |
2024-02-10 |
mouse |
| Hong-He Xiao, Feng-Rong Zhang, Sen Li, Fei-Fei Guo, Jin-Li Hou, Shi-Cong Wang, Juan Yu, Xian-Yu Li, Hong-Jun Yan. Xinshubao tablet rescues cognitive dysfunction in a mouse model of vascular dementia: Involvement of neurogenesis and neuroinflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-04. PMID:38310654. |
our findings revealed that oral administration of xsb rescued the cardiac dysfunction resulting from bilateral common carotid artery stenosis (bcas), improved the cerebral blood flow (cbf) and cognitive function, reduced white matter injury, inhibited excessive microglial and astrocytic activation, stimulated hippocampal neurogenesis, and reduced neural apoptosis in the brains of bcas mice. |
2024-02-04 |
2024-02-07 |
mouse |
| Xuebing Zhang, Suihong Huang, Jin Young Ki. Cell-type specific circadian transcription factor BMAL1 roles in excitotoxic hippocampal lesions to enhance neurogenesis. iScience. vol 27. issue 2. 2024-02-02. PMID:38303690. |
in the dentate gyrus of excitotoxic hippocampal lesions, reduced bmal1 in granule cells precedes apoptosis. |
2024-02-02 |
2024-02-04 |
Not clear |
| Guang-Jun Hu, Xiao-Yang Jiang, Si-Yu Du, Kun Zhang, Zhuo Che. miR-107-5p ameliorates neurological damage, oxidative stress, and immune responses in mice with Alzheimer's disease by suppressing the Toll-like receptor 4 (TLR4)/nuclear factor-kappaB(NF-κB) pathway. The Kaohsiung journal of medical sciences. vol 40. issue 2. 2024-02-02. PMID:38305705. |
histopathological changes, hippocampal neuron distribution, and apoptosis were assessed using hematoxylin-eosin, nissl, and tunel staining. |
2024-02-02 |
2024-02-04 |
mouse |
| Micaela Gliozzi, Anna Rita Coppoletta, Antonio Cardamone, Vincenzo Musolino, Cristina Carresi, Saverio Nucera, Stefano Ruga, Federica Scarano, Francesca Bosco, Lorenza Guarnieri, Roberta Macrì, Rocco Mollace, Catherine Belzung, Vincenzo Mollac. The dangerous "West Coast Swing" by hyperglycaemia and chronic stress in the mouse hippocampus: role of kynurenine catabolism. Pharmacological research. 2024-02-01. PMID:38301816. |
our work demonstrates that kynurenine overproduction, leading to apoptosis in the hippocampus, is triggered in a different way depending on hyperglycaemia or chronic stress. |
2024-02-01 |
2024-02-04 |
mouse |
| Micaela Gliozzi, Anna Rita Coppoletta, Antonio Cardamone, Vincenzo Musolino, Cristina Carresi, Saverio Nucera, Stefano Ruga, Federica Scarano, Francesca Bosco, Lorenza Guarnieri, Roberta Macrì, Rocco Mollace, Catherine Belzung, Vincenzo Mollac. The dangerous "West Coast Swing" by hyperglycaemia and chronic stress in the mouse hippocampus: role of kynurenine catabolism. Pharmacological research. 2024-02-01. PMID:38301816. |
we demonstrated that the coexistence of hyperglycaemia and chronic stress worsened hippocampal damage through alternative mechanisms, such as glut-4 and bdnf down-expression, denoting mitochondrial dysfunction and apoptosis on one hand and evoking the compromission of neurogenesis on the other. |
2024-02-01 |
2024-02-04 |
mouse |
| Jianbin Zhu, Haixiang Wei, Minying Jiang, Ting Li, Ruizhu Wu, Hualiang Che. Effect of Dexmedetomidine on Apoptosis and Early Cognitive Dysfunction in Rats Following Propofol Anesthesia. Alternative therapies in health and medicine. 2024-01-30. PMID:38290461. |
to address the intricate interplay between surgical anesthesia, hippocampal apoptosis, and early cognitive dysfunction in rats, this study delves into the impact of dexmedetomidine (dex). |
2024-01-30 |
2024-02-02 |
rat |
| Mrunal Nannaware, Neelaambhigai Mayilswamy, Balasubramanian Kandasubramania. PFAS: exploration of neurotoxicity and environmental impact. Environmental science and pollution research international. 2024-01-26. PMID:38277101. |
animal studies reveal apoptosis and hippocampus dysfunction, resulting in memory loss and spatial learning issues. |
2024-01-26 |
2024-01-28 |
human |
| Lan Wu, Xiang-Jian Meng, Tian-Bao Xu, Xian-Cui Zhang, Yong Zhou, Zhu-Feng Tong, Jing-Han Jian. Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes. Chemical biology & drug design. vol 103. issue 1. 2024-01-17. PMID:38230770. |
berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes. |
2024-01-17 |
2024-01-19 |
human |