| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masayuki Niwa, Akira Hara, Ayako Taguchi, Hitomi Aoki, Osamu Kozawa, Hideki Mor. Spatiotemporal expression of Hsp20 and its phosphorylation in hippocampal CA1 pyramidal neurons after transient forebrain ischemia. Neurological research. vol 31. issue 7. 2009-09-17. PMID:19055877. |
the emerging expression of the hsp20 protein within the restricted location of ca1 before the fragmented dna transport suggests the strong relationship between hsp20 and ca1 neuronal cell apoptosis. |
2009-09-17 |
2023-08-12 |
Not clear |
| Peter Racay, Maria Chomova, Zuzana Tatarkova, Peter Kaplan, Jozef Hatok, Dusan Dobrot. Ischemia-induced mitochondrial apoptosis is significantly attenuated by ischemic preconditioning. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19283470. |
detection of genomic dna fragmentation as well as fluoro-jade c staining showed that ischemia induces apoptosis in vulnerable ca1 layer of rat hippocampus. |
2009-08-19 |
2023-08-12 |
rat |
| Yong-xing Tan, Di-fen Wang, Xue-mei Li, Xing-min Li. [Effects of nerve growth factor pretreatment on apoptosis of neurons and expression of Bcl-2, Bax protein in brain tissue following cerebral ischemia/reperfusion injury in gerbils]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 19. issue 6. 2009-07-09. PMID:17577445. |
to study the effect of nerve growth factor (ngf) pretreatment on apoptosis of neurons and the expression of bcl-2 and bax protein in cerebral cortex and hippocampus ca1 zone following global cerebral ischemia/reperfusion (i/r) injury in gerbils and to explore the mechanism of protection and the best time window of ngf pretreatment. |
2009-07-09 |
2023-08-12 |
Not clear |
| Sébastien A Blaise, Emmanuelle Nédélec, Jean-Marc Alberto, Henri Schroeder, Sandra Audonnet, Carine Bossenmeyer-Pourié, Jean-Louis Guéant, Jean-Luc Dava. Short hypoxia could attenuate the adverse effects of hyperhomocysteinemia on the developing rat brain by inducing neurogenesis. Experimental neurology. vol 216. issue 1. 2009-03-20. PMID:19124018. |
while having no influence on brain accumulation of homocysteine and concomitant apoptosis in 21-day-old deficient pups, exposure to hypoxia reduced morphological injury of the hippocampal ca1 layer. |
2009-03-20 |
2023-08-12 |
rat |
| P Morales, J L Fiedler, S Andrés, C Berrios, P Huaiquín, D Bustamante, S Cardenas, E Parra, M Herrera-Marschit. Plasticity of hippocampus following perinatal asphyxia: effects on postnatal apoptosis and neurogenesis. Journal of neuroscience research. vol 86. issue 12. 2009-03-16. PMID:18512760. |
there was an increase of apoptosis in ca1, ca3, and dentate gyrus (dg) and cell proliferation and neurogenesis in ca1, dg, and hilus regions of hippocampus 1 week after asphyxia. |
2009-03-16 |
2023-08-12 |
rat |
| b' Ulu\\xc3\\xa7 Yi\\xc5\\x9f, Semra Hiz Kurul, Abdullah Kumral, Kazim Tu\\xc4\\x9fyan, Serap Cilaker, Osman Yilmaz, Sermin Gen\\xc3\\xa7, K\\xc3\\xbcr\\xc5\\x9fat Gen\\xc3\\xa. Effect of erythropoietin on oxygen-induced brain injury in the newborn rat. Neuroscience letters. vol 448. issue 3. 2009-02-24. PMID:18973793.' |
histopathological examination showed that erythropoietin significantly diminished apoptosis in the ca1 region and dentate gyrus of hippocampus and parietal cortex in hyperoxia+erythropoietin-treated group. |
2009-02-24 |
2023-08-12 |
human |
| Silvia Zucchini, Andrea Buzzi, Mario Barbieri, Donata Rodi, Beatrice Paradiso, Anna Binaschi, J Douglas Coffin, Andrea Marzola, Pierangelo Cifelli, Ottorino Belluzzi, Michele Simonat. Fgf-2 overexpression increases excitability and seizure susceptibility but decreases seizure-induced cell loss. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 49. 2009-01-12. PMID:19052202. |
in contrast, cell damage (assessed with fluoro-jade b, silver impregnation and anti-caspase 3 immunohistochemistry) was significantly lower in tgfgf2 mice, especially in the areas of overexpression (ca1 and ca3), indicating reduction of seizure-induced necrosis and apoptosis. |
2009-01-12 |
2023-08-12 |
mouse |
| Uluç Yiş, Semra Hiz Kurul, Abdullah Kumral, Serap Cilaker, Kazim Tuğyan, Sermin Genç, Osman Yilma. Hyperoxic exposure leads to cell death in the developing brain. Brain & development. vol 30. issue 9. 2008-10-15. PMID:18329209. |
the neuronal density and apoptosis in ca1 and dentate gyrus of hippocampus, prefrontal cortex, parietal cortex, subiculum, and retrosplenial cortex were assessed by immunohistochemistry and elisa cell death assay. |
2008-10-15 |
2023-08-12 |
rat |
| M Morita, H Imai, Y Liu, X Xu, M Sadamatsu, R Nakagami, T Shirakawa, K Nakano, Y Kita, K Yoshida, K Tsunashima, N Kat. FK506-protective effects against trimethyltin neurotoxicity in rats: hippocampal expression analyses reveal the involvement of periarterial osteopontin. Neuroscience. vol 153. issue 4. 2008-10-08. PMID:18440706. |
our data suggest that inflammatory gene expression is involved in tmt-induced damage to the hippocampal ca1 region, resulting in apoptosis, and that this process is initiated by periarterial opn activation, and can be alleviated by fk506. |
2008-10-08 |
2023-08-12 |
rat |
| D Kumaran, M Udayabanu, R Unnikrishnan Nair, Aneja R, Anju Katya. Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia. Behavioural brain research. vol 192. issue 2. 2008-09-30. PMID:18501976. |
the observed memory impairment in vehicle treated ischemia group was found to be well correlated with dnd and downregulation of cholinergic muscarinic receptor-1 expression, which was possibly mediated by inflammation and apoptosis, as revealed from inducible nitric oxide synthase (inos) expression and number of tunel positive neurons in hippocampus ca1 region. |
2008-09-30 |
2023-08-12 |
mouse |
| S Kaloustian, B P Wann, T M Bah, S A Girard, A Apostolakis, S Ishak, S Mathieu, P Ryvlin, R Godbout, G Roussea. Apoptosis time course in the limbic system after myocardial infarction in the rat. Brain research. vol 1216. 2008-09-08. PMID:18495089. |
both apoptosis parameters were increased throughout, although in different structures: the ca1 region of the hippocampus and the medial amygdala at day 1, the ca1 region of the hippocampus and the lateral amygdala at day 2, and the frontal cortex at day 7. |
2008-09-08 |
2023-08-12 |
rat |
| HongYu Xue, LiJi Jin, Lei Jin, Peng Zhang, DanQing Li, YanQiu Xia, YaNan Lu, YongPing X. Neuroprotection of aucubin in primary diabetic encephalopathy. Science in China. Series C, Life sciences. vol 51. issue 6. 2008-09-03. PMID:18488169. |
rats were euthanized on day 87, and hippocampi were excised for visual (light and transmission electron microscopic) and immunochemical (western blot; immunohistochemical) assessments of the ca1 subfield for apoptosis and expression of regulatory proteins bcl-2 and bax. |
2008-09-03 |
2023-08-12 |
rat |
| Sunil K Hota, Kalpana Barhwal, Shashi B Singh, G Ilavazhaga. Chronic hypobaric hypoxia induced apoptosis in CA1 region of hippocampus: a possible role of NMDAR mediated p75NTR upregulation. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18466900. |
chronic hypobaric hypoxia induced apoptosis in ca1 region of hippocampus: a possible role of nmdar mediated p75ntr upregulation. |
2008-07-17 |
2023-08-12 |
rat |
| Sunil K Hota, Kalpana Barhwal, Shashi B Singh, G Ilavazhaga. Chronic hypobaric hypoxia induced apoptosis in CA1 region of hippocampus: a possible role of NMDAR mediated p75NTR upregulation. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18466900. |
further, reduced expression of p75(ntr) expression by antisense nucleotide administration significantly decreased apoptosis in the ca1 region of hippocampus. |
2008-07-17 |
2023-08-12 |
rat |
| Xue-Mei Zong, Ya-Feng Sun, Dong-Sheng Pei, Yin-Ming Zeng, Tie X. Pergolide protects CA1 neurons from apoptosis in a gerbil model of global cerebral ischemia. Neurological research. vol 30. issue 1. 2008-06-20. PMID:17767807. |
pergolide protects ca1 neurons from apoptosis in a gerbil model of global cerebral ischemia. |
2008-06-20 |
2023-08-12 |
Not clear |
| Xue-Mei Zong, Ya-Feng Sun, Dong-Sheng Pei, Yin-Ming Zeng, Tie X. Pergolide protects CA1 neurons from apoptosis in a gerbil model of global cerebral ischemia. Neurological research. vol 30. issue 1. 2008-06-20. PMID:17767807. |
to investigate the effects of dopamine (da) receptor agonists and antagonists on neuronal apoptosis in hippocampal ca1 region after forebrain ischemia/reperfusion (i/r) injury in gerbils. |
2008-06-20 |
2023-08-12 |
Not clear |
| Jung-Mi Han, Byung-Joon Chang, Tian-Zhu Li, Nong-Hoon Choe, Fu-Shi Quan, Bong-Jun Jang, Ik-Hyun Cho, Hea-Nam Hong, Jong-Hwan Le. Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo. Brain research. vol 1185. 2008-03-28. PMID:17959157. |
histopathological evaluation demonstrated that ascorbic acid significantly attenuates apoptosis in the developing hippocampus and also spares hippocampal ca1, ca3 and dentate gyrus (dg) neurons. |
2008-03-28 |
2023-08-12 |
rat |
| Yujuan Li, Ge Liang, Shouping Wang, Qingcheng Meng, Qiujun Wang, Huafeng We. Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:17959201. |
rat fetal exposure to isoflurane at pregnancy day 21 through maternal anesthesia significantly decreased spontaneous apoptosis in the hippocampal ca1 region and in the retrosplenial cortex at 2h after exposure, but not at 18h or at p5. |
2008-03-21 |
2023-08-12 |
rat |
| Takuya Watanabe, Katsunori Iwasaki, Shin Ishikane, Tetsuya Naitou, Yoshitaka Yoshimitsu, Norito Yamagata, Mehmeto Bülent Ozdemir, Kotaro Takasaki, Nobuaki Egashira, Kenichi Mishima, Michihiro Fujiwar. Spatial memory impairment without apoptosis induced by the combination of beta-amyloid oligomers and cerebral ischemia is related to decreased acetylcholine release in rats. Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18187922. |
in the present study, the combination of abeta oligomers and cerebral ischemia, but not cerebral ischemia alone, significantly impaired spatial memory without apoptosis in the ca1 region of the hippocampus. |
2008-03-04 |
2023-08-12 |
rat |
| Simon J Fung, Ming-Chu Xi, Jian-Hua Zhang, Sharon Sampogna, Jack Yamuy, Francisco R Morales, Michael H Chas. Apnea promotes glutamate-induced excitotoxicity in hippocampal neurons. Brain research. vol 1179. 2008-01-17. PMID:17888415. |
we therefore conclude that recurrent apnea produces abnormally high levels of glutamate that results in the apoptosis of ca1 neurons. |
2008-01-17 |
2023-08-12 |
Not clear |