| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Rami, M Kim, J Nique. Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:21132459. |
in this study, we analyzed the contribution of serine protease omi/htra2, its substrate x-linked inhibitor of apoptosis protein (xiap) and the caspase-3 activation to damage of hippocamplal ca1 cells following lithium-pilocarpine se in p14 rat pups. |
2011-04-28 |
2023-08-12 |
rat |
| Nobuhiro Osada, Yasuhiro Kosuge, Kumiko Ishige, Yoshihisa It. Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia. Neurochemistry international. vol 57. issue 1. 2011-01-31. PMID:20362024. |
in addition to neuronal injury, astrocytes in area ca1 undergo apoptosis under ischemic conditions. |
2011-01-31 |
2023-08-12 |
mouse |
| Nobuhiro Osada, Yasuhiro Kosuge, Kumiko Ishige, Yoshihisa It. Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia. Neurochemistry international. vol 57. issue 1. 2011-01-31. PMID:20362024. |
these results suggest that astrocytes as well as pyramidal neurons in area ca1 undergo apoptosis through an er stress-dependent mechanism after ischemia. |
2011-01-31 |
2023-08-12 |
mouse |
| Iu V Lebid', V Ie Dosenko, H H Skyb. [Expression of proteasome subunits PSMB5 and PSMB9 mRNA in hippocampal neurons in experimental diabetes mellitus: link with apoptosis and necrosis]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 56. issue 4. 2010-11-30. PMID:20968039. |
the goal of this work was to investigate the expression of proteasome subunits psmb5 and psmb9 mrna in ca1, ca2 and ca3 areas of hippocampus in parallel with processes of cell death (apoptosis and necrosis) in development dynamics of streptozotocine-induced diabetes. |
2010-11-30 |
2023-08-12 |
Not clear |
| Ye Peng, Shu-Fang Feng, Qiang Wang, Hua-Ning Wang, Wu-Gang Hou, Lize Xiong, Zhuo-Jing Luo, Qing-Rong Ta. Hyperbaric oxygen preconditioning ameliorates anxiety-like behavior and cognitive impairments via upregulation of thioredoxin reductases in stressed rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 6. 2010-11-02. PMID:20493230. |
the results indicated that hbo-pc was able to significantly preserve viable neurons in the ca1 subfield of hippocampus following sps exposure, as evidenced by reduced amounts of ca1 neuronal apoptosis. |
2010-11-02 |
2023-08-12 |
rat |
| Shufang Feng, Qiang Wang, Huaning Wang, Ye Peng, Lei Wang, Yan Lu, Tianyao Shi, Lize Xion. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neuroscience letters. vol 478. issue 3. 2010-10-08. PMID:20457216. |
our results showed that +gz exposure significantly caused pyramidal neuronal damage, increased neuronal apoptosis and caspase-3 activity in hippocampal ca1 region, as well as resulted in an impairment of spatial learning and memory, as compared to the sham group animals. |
2010-10-08 |
2023-08-12 |
rat |
| Shufang Feng, Qiang Wang, Huaning Wang, Ye Peng, Lei Wang, Yan Lu, Tianyao Shi, Lize Xion. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neuroscience letters. vol 478. issue 3. 2010-10-08. PMID:20457216. |
furthermore, the ea pretreatment significantly attenuated the neuronal apoptosis, preserved neuronal morphology and inhibited the caspase-3 activity in hippocampal ca1 region resulted from +gz exposure. |
2010-10-08 |
2023-08-12 |
rat |
| Helena P Bonner, Caoimhín G Concannon, Caroline Bonner, Ina Woods, Manus W Ward, Jochen H M Preh. Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability. Journal of neurochemistry. vol 114. issue 2. 2010-08-23. PMID:20477911. |
genetic deletion of the pro-apoptotic p53 target gene, p53-upregulated modulator of apoptosis (puma), significantly reduced injury within the ca1 following proteasomal inhibition. |
2010-08-23 |
2023-08-12 |
Not clear |
| Hui-guo Liu, Zhi-feng Zhang, Zhen-xiang Zhang, Yong-ping Gao, Ru-ji Ni. [The change and mechanism of apoptosis in the hippocampal CA1 region of rats exposed to intermittent hypoxia]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 30. issue 5. 2010-08-17. PMID:17651645. |
[the change and mechanism of apoptosis in the hippocampal ca1 region of rats exposed to intermittent hypoxia]. |
2010-08-17 |
2023-08-12 |
rat |
| Hui-guo Liu, Zhi-feng Zhang, Zhen-xiang Zhang, Yong-ping Gao, Ru-ji Ni. [The change and mechanism of apoptosis in the hippocampal CA1 region of rats exposed to intermittent hypoxia]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 30. issue 5. 2010-08-17. PMID:17651645. |
to investigate the effect of intermittent hypoxia on rat hippocampal oxidative stress and neuron apoptosis in the hippocampal ca1 region. |
2010-08-17 |
2023-08-12 |
rat |
| In Koo Hwang, Ki-Yeon Yoo, Dae Won Kim, Choong Hyun Lee, Jung Hoon Choi, Young-Guen Kwon, Young-Myeong Kim, Soo Young Choi, Moo-Ho Wo. Changes in the expression of mitochondrial peroxiredoxin and thioredoxin in neurons and glia and their protective effects in experimental cerebral ischemic damage. Free radical biology & medicine. vol 48. issue 9. 2010-06-16. PMID:20156553. |
these results suggest that changes in the expression of prx3 and trx2 in the hippocampal ca1 region after i/r may be associated with the delayed neuronal death of ca1 pyramidal cells induced by transient cerebral ischemia, and that treatment with prx3 or prx3/trx2 in ischemic brains shows a potent neuroprotective effect against ischemic damage by reducing lipid peroxidation and mitochondrial-mediated apoptosis by i/r. |
2010-06-16 |
2023-08-12 |
Not clear |
| Xiang-Rong Zheng, Shan-Shan Zhang, Yu-Jia Yang, Fei Yin, Xia Wang, Le Zhong, Xiao-He Y. Adenoviral vector-mediated transduction of VEGF improves neural functional recovery after hypoxia-ischemic brain damage in neonatal rats. Brain research bulletin. vol 81. issue 4-5. 2010-05-06. PMID:19945513. |
the better performs by the animals that received vegf vectors may be directly linked to the inhibitory effect of vegf on neuronal apoptosis because the animals had less neural loss in the cortex and hippocampal ca1 region as compared with pbs group. |
2010-05-06 |
2023-08-12 |
human |
| Jun-Li Liu, Dai-Shi Tian, Zai-Wang Li, Wen-Sheng Qu, Yan Zhan, Min-Jie Xie, Zhi-Yuan Yu, Wei Wang, Gang W. Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. Brain research. vol 1316. 2010-05-06. PMID:20044983. |
furthermore, wbi led to microglial activation and reactive astrogliosis in the cerebral cortex and neuronal apoptosis in the ca1 hippocampus at day 3 post-radiation. |
2010-05-06 |
2023-08-12 |
Not clear |
| Shouping Wang, Kelly Peretich, Yifan Zhao, Ge Liang, Qingcheng Meng, Huafeng We. Anesthesia-induced neurodegeneration in fetal rat brains. Pediatric research. vol 66. issue 4. 2010-02-05. PMID:20016413. |
fetal brains were then evaluated for apoptosis, using caspase-3 immunohistochemistry in the ca1 region of the hippocampus and the retrosplenial cortex (rs). |
2010-02-05 |
2023-08-12 |
rat |
| T Yawno, J J Hirst, M Castillo-Melendez, D W Walke. Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain. Neuroscience. vol 163. issue 3. 2010-01-14. PMID:19591903. |
finasteride treatment significantly increased apoptosis (activated caspase-3 expression) in hippocampal ca3 and ca1, and cerebellar molecular and granular layers, an effect abolished by co-infusion of alfaxalone and finasteride. |
2010-01-14 |
2023-08-12 |
Not clear |
| b' S H Kurul, U Yi\\xc5\\x9f, A Kumral, K Tu\\xc4\\x9fyan, S Cilaker, E Kolatan, O Yilmaz, S Gen\\xc3\\xa. Protective effects of topiramate against hyperoxic brain injury in the developing brain. Neuropediatrics. vol 40. issue 1. 2009-10-16. PMID:19639524.' |
histopathological examination showed that topiramate significantly diminished apoptosis in the ca1 region and dentate gyrus of hippocampus. |
2009-10-16 |
2023-08-12 |
rat |
| Masayuki Niwa, Akira Hara, Ayako Taguchi, Hitomi Aoki, Osamu Kozawa, Hideki Mor. Spatiotemporal expression of Hsp20 and its phosphorylation in hippocampal CA1 pyramidal neurons after transient forebrain ischemia. Neurological research. vol 31. issue 7. 2009-09-17. PMID:19055877. |
the emerging expression of the hsp20 protein within the restricted location of ca1 before the fragmented dna transport suggests the strong relationship between hsp20 and ca1 neuronal cell apoptosis. |
2009-09-17 |
2023-08-12 |
Not clear |
| Peter Racay, Maria Chomova, Zuzana Tatarkova, Peter Kaplan, Jozef Hatok, Dusan Dobrot. Ischemia-induced mitochondrial apoptosis is significantly attenuated by ischemic preconditioning. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19283470. |
detection of genomic dna fragmentation as well as fluoro-jade c staining showed that ischemia induces apoptosis in vulnerable ca1 layer of rat hippocampus. |
2009-08-19 |
2023-08-12 |
rat |
| Yong-xing Tan, Di-fen Wang, Xue-mei Li, Xing-min Li. [Effects of nerve growth factor pretreatment on apoptosis of neurons and expression of Bcl-2, Bax protein in brain tissue following cerebral ischemia/reperfusion injury in gerbils]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 19. issue 6. 2009-07-09. PMID:17577445. |
to study the effect of nerve growth factor (ngf) pretreatment on apoptosis of neurons and the expression of bcl-2 and bax protein in cerebral cortex and hippocampus ca1 zone following global cerebral ischemia/reperfusion (i/r) injury in gerbils and to explore the mechanism of protection and the best time window of ngf pretreatment. |
2009-07-09 |
2023-08-12 |
Not clear |
| Sébastien A Blaise, Emmanuelle Nédélec, Jean-Marc Alberto, Henri Schroeder, Sandra Audonnet, Carine Bossenmeyer-Pourié, Jean-Louis Guéant, Jean-Luc Dava. Short hypoxia could attenuate the adverse effects of hyperhomocysteinemia on the developing rat brain by inducing neurogenesis. Experimental neurology. vol 216. issue 1. 2009-03-20. PMID:19124018. |
while having no influence on brain accumulation of homocysteine and concomitant apoptosis in 21-day-old deficient pups, exposure to hypoxia reduced morphological injury of the hippocampal ca1 layer. |
2009-03-20 |
2023-08-12 |
rat |