| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Ozawa, S Shioda, K Dohi, H Matsumoto, H Mizushima, C J Zhou, H Funahashi, Y Nakai, S Nakajo, K Matsumot. Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway. Neuroscience letters. vol 262. issue 1. 1999-05-06. PMID:10076872. |
these results with other previous studies suggest that the activation of jnk/sapk in accordance with p38 contributes to the induction of apoptosis in ca1 neurons. |
1999-05-06 |
2023-08-12 |
rat |
| Y H Kim, E Y Kim, B J Gwag, S Sohn, J Y Ko. Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals. Neuroscience. vol 89. issue 1. 1999-04-26. PMID:10051227. |
some studies have provided evidence that delayed death of hippocampal ca1 neurons in transient global ischemia occurs by classical apoptosis. |
1999-04-26 |
2023-08-12 |
mouse |
| Y Nomur. A transient brain ischemia- and bacterial endotoxin-induced glial iNOS expression and NO-induced neuronal apoptosis. Toxicology letters. vol 102-103. 1999-02-25. PMID:10022234. |
we found that a transient four-vessel occlusion/reperfusion induced glial inos expression and neuronal apoptosis in a ca1 region of the rat hippocampus. |
1999-02-25 |
2023-08-12 |
rat |
| S Shioda, H Ozawa, K Dohi, H Mizushima, K Matsumoto, S Nakajo, A Takaki, C J Zhou, Y Nakai, A Arimur. PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928003. |
we have demonstrated that the ischemia-induced apoptosis of neurons in the ca1 region of the rat hippocampus was prevented by either intracerebroventricular or intravenous infusion of pituitary adenylate cyclase-activating polypeptide (pacap). |
1999-02-16 |
2023-08-12 |
rat |
| M Walton, G MacGibbon, D Young, E Sirimanne, C Williams, P Gluckman, M Draguno. Do c-Jun, c-Fos, and amyloid precursor protein play a role in neuronal death or survival? Journal of neuroscience research. vol 53. issue 3. 1998-10-21. PMID:9698161. |
in addition to changes in immediate early gene expression, the ca1 neurons showed a delayed increase in the expression of amyloid precursor protein (app751) mrna, suggesting that app, which contains an ap-1 site, might be a down-stream gene regulated by the jun transcription factor in neurons dying by apoptosis. |
1998-10-21 |
2023-08-12 |
rat |
| J J Miguel-Hidalgo, R Cacabelo. Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta neuropathologica. vol 95. issue 5. 1998-07-13. PMID:9600591. |
in animals injected with abeta 1-40, many profiles in the ca1 subfield and dentate gyrus were undergoing apoptosis, as seen using preparations processed by routine histology or the tunel technique for detection of fragmented dna. |
1998-07-13 |
2023-08-12 |
rat |
| E M Aronica, J A Gorter, S Grooms, J A Kessler, M V Bennett, R S Zukin, D M Rosenbau. Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 12. 1998-07-09. PMID:9618548. |
aurintricarboxylic acid (ata), an inhibitor of endonuclease activity and other protein-nucleic acid interactions, blocks apoptosis in several cell types and prevents delayed death of hippocampal pyramidal ca1 neurons induced by transient global ischemia. |
1998-07-09 |
2023-08-12 |
rat |
| E M Aronica, J A Gorter, S Grooms, J A Kessler, M V Bennett, R S Zukin, D M Rosenbau. Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 12. 1998-07-09. PMID:9618548. |
this result and neuroprotection by antagonists of ampa receptors suggests that formation of ampa receptors lacking glur2, and therefore ca2+ permeable, leads to excessive ca2+ influx in response to endogenous glutamate; the resulting delayed neuronal death in ca1 exhibits many characteristics of apoptosis. |
1998-07-09 |
2023-08-12 |
rat |
| M Maeda, T Sugiyama, F Akai, I Jikihara, Y Hayashi, H Takag. Single stranded DNA as an immunocytochemical marker for apoptotic change of ischemia in the gerbil hippocampus. Neuroscience letters. vol 240. issue 2. 1998-04-02. PMID:9486474. |
these findings suggest that ssd degradation can occur during delayed neuronal death in the ca1, preceding the appearance of double strand breaks, one of the characteristic features of apoptosis. |
1998-04-02 |
2023-08-12 |
Not clear |
| Z S Nagy, M M Esir. Apoptosis-related protein expression in the hippocampus in Alzheimer's disease. Neurobiology of aging. vol 18. issue 6. 1998-03-05. PMID:9461054. |
in contrast bax, a protein that is believed to promote apoptosis, was widely expressed by neurones but was mainly present in areas other than ca1 in the hippocampus. |
1998-03-05 |
2023-08-12 |
Not clear |
| C K Petito, J Torres-Munoz, B Roberts, J P Olarte, T S Nowak, W A Pulsinell. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 17. issue 9. 1997-10-14. PMID:9307610. |
they suggest that mechanisms other than apoptosis may mediate the irreversible changes in the ca1 neurons in this model. |
1997-10-14 |
2023-08-12 |
rat |
| A Williams, P J Lucassen, D Ritchie, M Bruc. PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie. Experimental neurology. vol 144. issue 2. 1997-06-19. PMID:9168844. |
electron microscopy of the ca1 region at 105 days confirmed that these neurons were dying by apoptosis. |
1997-06-19 |
2023-08-12 |
mouse |
| C G Wasterlain, L M Adams, J K Wichmann, R D Sofi. Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia. Stroke. vol 27. issue 7. 1996-08-22. PMID:8685935. |
felbamate protects ca1 neurons from apoptosis in a gerbil model of global ischemia. |
1996-08-22 |
2023-08-12 |
rat |
| C G Wasterlain, L M Adams, J K Wichmann, R D Sofi. Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia. Stroke. vol 27. issue 7. 1996-08-22. PMID:8685935. |
the present study explores its neuroprotective potential in a gerbil model of global ischemia, in which good evidence exists that ischemia triggers apoptosis of ca1. |
1996-08-22 |
2023-08-12 |
rat |
| J P MacManus, A M Buchan, I E Hill, I Rasquinha, E Presto. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neuroscience letters. vol 164. issue 1-2. 1994-05-09. PMID:8152622. |
laddered dna indicative of apoptosis was observed in the ca1 layer of hippocampus and in dorsolateral striatum following a global cerebral ischemic insult produced by transient two vessel occlusion in rats. |
1994-05-09 |
2023-08-12 |
rat |