| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Fukai, M Mashimo, K Akiyama, T Goto, S Tanuma, T Katayam. Modulation of apoptotic cell death by extracellular matrix proteins and a fibronectin-derived antiadhesive peptide. Experimental cell research. vol 242. issue 1. 1998-08-10. PMID:9665806. |
peptide iii14-2, which had no effect by itself on the huvec apoptosis, disrupted the ligation of alpha 5 beta 1 and alpha v beta 3 but no alpha 2 beta 1 and ultimately led the cells to apoptosis, indicating that this antiadhesive peptide indirectly induces apoptosis by blocking cell survival signal delivered from alpha 5 beta 1 and alpha v beta 3 integrins. |
1998-08-10 |
2023-08-12 |
human |
| M A Glozak, M B Roger. BMP4- and RA-induced apoptosis is mediated through the activation of retinoic acid receptor alpha and gamma in P19 embryonal carcinoma cells. Experimental cell research. vol 242. issue 1. 1998-08-10. PMID:9665814. |
bmp4- and ra-induced apoptosis is mediated through the activation of retinoic acid receptor alpha and gamma in p19 embryonal carcinoma cells. |
1998-08-10 |
2023-08-12 |
Not clear |
| M A Glozak, M B Roger. BMP4- and RA-induced apoptosis is mediated through the activation of retinoic acid receptor alpha and gamma in P19 embryonal carcinoma cells. Experimental cell research. vol 242. issue 1. 1998-08-10. PMID:9665814. |
by using receptor-selective retinoid agonists and antagonists, we have obtained evidence suggesting that activation of rar alpha or gamma is sufficient to induce apoptosis in bmp4-treated cells. |
1998-08-10 |
2023-08-12 |
Not clear |
| A Foghi, K J Teerds, H van der Donk, N C Moore, J Dorringto. Induction of apoptosis in thecal/interstitial cells: action of transforming growth factor (TGF) alpha plus TGF beta on bcl-2 and interleukin-1 beta-converting enzyme. The Journal of endocrinology. vol 157. issue 3. 1998-08-10. PMID:9691982. |
induction of apoptosis in thecal/interstitial cells: action of transforming growth factor (tgf) alpha plus tgf beta on bcl-2 and interleukin-1 beta-converting enzyme. |
1998-08-10 |
2023-08-12 |
caenorhabditis_elegans |
| A Foghi, K J Teerds, H van der Donk, N C Moore, J Dorringto. Induction of apoptosis in thecal/interstitial cells: action of transforming growth factor (TGF) alpha plus TGF beta on bcl-2 and interleukin-1 beta-converting enzyme. The Journal of endocrinology. vol 157. issue 3. 1998-08-10. PMID:9691982. |
we have previously shown that treatment of subconfluent cultures of thecal/interstitial cells (t/i) with transforming growth factor (tgf) alpha plus tgf beta caused chromatin condensation and internucleosomal fragmentation characteristic of apoptosis, whereas in the presence of either tgf alpha or tgf beta alone the cells remained healthy. |
1998-08-10 |
2023-08-12 |
caenorhabditis_elegans |
| A Foghi, K J Teerds, H van der Donk, N C Moore, J Dorringto. Induction of apoptosis in thecal/interstitial cells: action of transforming growth factor (TGF) alpha plus TGF beta on bcl-2 and interleukin-1 beta-converting enzyme. The Journal of endocrinology. vol 157. issue 3. 1998-08-10. PMID:9691982. |
dna analysis showed that dna fragmentation, indicative of apoptosis, occurred after 10 h of treatment with tgf alpha plus tgf beta. |
1998-08-10 |
2023-08-12 |
caenorhabditis_elegans |
| K A Buzzard, A J Giaccia, M Killender, R L Anderso. Heat shock protein 72 modulates pathways of stress-induced apoptosis. The Journal of biological chemistry. vol 273. issue 27. 1998-08-06. PMID:9642282. |
the induction of thermotolerance protects cells from heat, tumor necrosis factor alpha (tnfalpha), and ceramide-induced apoptosis but not from ionizing radiation. |
1998-08-06 |
2023-08-12 |
mouse |
| Y Ikeda, J Shinozuka, T Miyazawa, K Kurosawa, Y Izumiya, Y Nishimura, K Nakamura, J Cai, K Fujita, K Doi, T Mikam. Apoptosis in feline panleukopenia virus-infected lymphocytes. Journal of virology. vol 72. issue 8. 1998-08-05. PMID:9658149. |
feline panleukopenia virus (fplv) was shown to induce apoptosis to feline lymphoid cells and to reduce the expression of interleukin-2 receptor alpha on the cells. |
1998-08-05 |
2023-08-12 |
Not clear |
| S Spiegel, O Cuvillier, L C Edsall, T Kohama, R Menzeleev, Z Olah, A Olivera, G Pirianov, D M Thomas, Z Tu, J R Van Brocklyn, F Wan. Sphingosine-1-phosphate in cell growth and cell death. Annals of the New York Academy of Sciences. vol 845. 1998-08-04. PMID:9668339. |
while ceramide has been shown to be an important regulatory component of apoptosis induced by tumor necrosis factor alpha and fas ligand, sphingosine-1-phosphate (spp), a further metabolite of ceramide, has been implicated as a second messenger in cellular proliferation and survival induced by platelet-derived growth factor, nerve growth factor, and serum. |
1998-08-04 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
regulation of apoptosis by tyrosine-containing domains of il-4r alpha: y497 and y713, but not the stat6-docking tyrosines, signal protection from apoptosis. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
we have analyzed the role that tyrosine-containing domains within the cytoplasmic tail of il-4r alpha play in il-4-mediated protection from apoptosis. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
32d cells expressing a wt huil-4r alpha or one truncated at aa 557 were protected by huil-4 from apoptosis while cells expressing a receptor truncated at aa 657 were not, suggesting that the carboxyl-terminal domain signals protection from apoptosis. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
to analyze the contribution of tyrosine-containing domains independently, we transplanted regions of the huil-4r alpha to a truncated form of the huil-2r beta that could not signal protection from apoptosis. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
transplantation of the huil-4r alpha domains containing y497 or y713 partially prevented cell death and together signaled protection from apoptosis in response to il-2 as well as the wt il-2r beta. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
although il-4r alpha signals shc and sh2-containing inositol phosphatase (ship) phosphorylation, we could not establish an association between their activation and protection from apoptosis. |
1998-07-30 |
2023-08-12 |
Not clear |
| J Zamorano, A D Keega. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 2. 1998-07-30. PMID:9670964. |
taken together, this study suggests that the domains of the huil-4r alpha containing y497 and y713 positively regulate protection from apoptosis while the domain containing the stat6 docking sites suppresses this protection, and that additional signaling molecules other than insulin receptor substrate-1 (irs1), shc, or ship may be involved in antiapoptotic signaling. |
1998-07-30 |
2023-08-12 |
Not clear |
| A Satone, H Ukita, H Murakami, S Chiba, Y Oshima, A Ogata, M Ikeda, H Yamaguchi, A Matsumoto, W Ide, I Hashimoto, H Kamad. [Neural protective agents, propentofylline (PPF) could induce apoptotic cell death in the human glioma cells: analysis of Bcl-2 and Bax alpha/Bax beta expressions]. No to shinkei = Brain and nerve. vol 50. issue 4. 1998-07-24. PMID:9592822. |
thus over-expression of the bcl-2 and bax alpha gene renders the glioma cells resistant to apoptosis. |
1998-07-24 |
2023-08-12 |
human |
| L S Gill, V K Pabbathi, M Vignes, L W Hayne. Altered distribution of Galphah/type 2 transglutaminase following catecholamine deprivation is associated with depression of adrenoreceptor signal transduction in cultured ventricular zone germinal cells. Brain research. vol 788. issue 1-2. 1998-07-23. PMID:9554967. |
type 2 transglutaminase (tg), which catalyzes the covalent cross-linking of cytoplasmic proteins during apoptosis, also functions as the alpha subunit of a heterodimeric g-protein (gh) which can activate phospholipase c-delta1 during the signal transduction pathway linked to alpha1-adrenoreceptors. |
1998-07-23 |
2023-08-12 |
rat |
| S Gopal, U Narasimhan, J D Day, R Gao, E K Kasper, C L Chen, S Cina, A L Robertson, R H Hruba. The Quilty lesion enigma: focal apoptosis/necrosis and lymphocyte subsets in human cardiac allografts. Pathology international. vol 48. issue 3. 1998-07-14. PMID:9589487. |
apoptosis, as identified by dna nick end-labeling, was found in myocytes at the periphery of quilty lesions in 11 of 13 cases (85%), and 'early' stages of myocyte necrosis, as demonstrated by specific staining with alpha light chain myosin monoclonal antibodies (mab), was observed at the same sites in 10 of 13 cases (77%) of both quilty type a and type b lesions. |
1998-07-14 |
2023-08-12 |
human |
| H Qian, G J Hausman, M M Compton, M J Azain, D L Hartzell, C A Bail. Leptin regulation of peroxisome proliferator-activated receptor-gamma, tumor necrosis factor, and uncoupling protein-2 expression in adipose tissues. Biochemical and biophysical research communications. vol 246. issue 3. 1998-07-02. PMID:9618269. |
the present study suggests that expression of ppar gamma may be directly involved in the leptin-induced adipocyte apoptosis signal pathway, whereas ucp2 and tnf alpha may play roles in the leptin-induced lipolysis process. |
1998-07-02 |
2023-08-12 |
rat |