Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
W J Murdoc. Regulation of collagenolysis and cell death by plasmin within the formative stigma of preovulatory ovine follicles. Journal of reproduction and fertility. vol 113. issue 2. 1999-01-12. PMID:9861174. |
apical plasmin bioactivity, collagenolysis, tnf-alpha-mediated fragmentation of cellular dna (a marker of apoptosis), stigma formation, and follicular rupture in sheep were inhibited by intrafollicular injection of alpha 2-antiplasmin. |
1999-01-12 |
2023-08-12 |
Not clear |
F M Young, P J Illingworth, H M Frase. Ubiquitin and apoptosis in the corpus luteum of the marmoset monkey (Callithrix jacchus). Journal of reproduction and fertility. vol 114. issue 1. 1999-01-11. PMID:9875169. |
these results indicate that ubiquitin expression is not specific for luteolysis and is not an indicator of luteal apoptosis, but that the polypeptide does play a role in luteal cellular responses to pgf2 alpha. |
1999-01-11 |
2023-08-12 |
monkey |
T Otsuki, O Yamada, H Sakaguchi, A Tomokuni, H Wada, Y Yawata, A Uek. Human myeloma cell apoptosis induced by interferon-alpha. British journal of haematology. vol 103. issue 2. 1998-12-29. PMID:9827928. |
in this study we investigated myeloma cell apoptosis induced by ifn alpha using five human myeloma cell lines which were established without any additional supplementation of il-6. |
1998-12-29 |
2023-08-12 |
human |
T Otsuki, O Yamada, H Sakaguchi, A Tomokuni, H Wada, Y Yawata, A Uek. Human myeloma cell apoptosis induced by interferon-alpha. British journal of haematology. vol 103. issue 2. 1998-12-29. PMID:9827928. |
in addition, the mrna expression levels of apoptosis-related genes employing the reverse transcriptase-polymerase chain reaction (rt-pcr) were also analysed with the kms-12-pe cell line, which was the most sensitive of the five cell lines in terms of apoptosis induced by ifn alpha. |
1998-12-29 |
2023-08-12 |
human |
T Otsuki, O Yamada, H Sakaguchi, A Tomokuni, H Wada, Y Yawata, A Uek. Human myeloma cell apoptosis induced by interferon-alpha. British journal of haematology. vol 103. issue 2. 1998-12-29. PMID:9827928. |
based on the results, it was determined that ifn alpha induced myeloma cell apoptosis in a dose-dependent manner, but the sensitivity to ifn alpha in the cell lines examined varied and one cell line revealed growth stimulation by ifn alpha. |
1998-12-29 |
2023-08-12 |
human |
T Otsuki, O Yamada, H Sakaguchi, A Tomokuni, H Wada, Y Yawata, A Uek. Human myeloma cell apoptosis induced by interferon-alpha. British journal of haematology. vol 103. issue 2. 1998-12-29. PMID:9827928. |
in addition, the apoptosis induced by ifn alpha did not seem to be mediated by the fas/fas ligand pathway. |
1998-12-29 |
2023-08-12 |
human |
T Otsuki, O Yamada, H Sakaguchi, A Tomokuni, H Wada, Y Yawata, A Uek. Human myeloma cell apoptosis induced by interferon-alpha. British journal of haematology. vol 103. issue 2. 1998-12-29. PMID:9827928. |
therefore these genes may play an important role during apoptosis induced by ifn alpha. |
1998-12-29 |
2023-08-12 |
human |
M S Sheikh, M J Antinore, Y Huang, A J Fornac. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene. vol 17. issue 20. 1998-12-23. PMID:9840918. |
uv-irradiation and tnf alpha acted in a synergistic manner to induce apoptosis. |
1998-12-23 |
2023-08-12 |
Not clear |
M Bittner, U Gosslar, A Luz, B Holzman. Sequence motifs in the integrin alpha 4 cytoplasmic tail required for regulation of in vivo expansion of murine lymphoma cells. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 11. 1998-12-21. PMID:9834079. |
cross-linking of alpha 4 integrins in vitro inhibited proliferation and induced apoptosis of lb cells expressing wild-type alpha 4 subunits or the alpha 4-1021 mutant, but not of lb-a4-1014 cells. |
1998-12-21 |
2023-08-12 |
mouse |
L Lindenboim, R Haviv, R Stei. Bcl-xL inhibits different apoptotic pathways in rat PC12 cells. Neuroscience letters. vol 253. issue 1. 1998-12-02. PMID:9754799. |
to study the mechanism of action of bcl-xl in a neuronal context, we generated rat pc12 cells overexpressing bcl-xl and examined their susceptibility to apoptotic stimuli that induce apoptosis through different pathways involving trophic-factor deprivation, staurosporine, tumor necrosis factor alpha or cisplatin. |
1998-12-02 |
2023-08-12 |
rat |
K Nason-Burchenal, G Takle, U Pace, S Flynn, J Allopenna, P Martin, S T George, A R Goldberg, E Dmitrovsk. Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells. Oncogene. vol 17. issue 14. 1998-11-25. PMID:9778041. |
targeting the pml/rar alpha translocation product triggers apoptosis in promyelocytic leukemia cells. |
1998-11-25 |
2023-08-12 |
Not clear |
G Yared, K B Hussain, M G Nathani, J A Moshier, J Dosescu, M G Mutchnick, P H Naylo. Cytokine-mediated apoptosis and inhibition of virus production and anchorage independent growth of viral transfected hepatoblastoma cells. Cytokine. vol 10. issue 8. 1998-11-24. PMID:9722931. |
ifn-alpha and t alpha 1 had no effect on apoptosis. |
1998-11-24 |
2023-08-12 |
human |
K Zemanová, J Smard. Oncoprotein v-Myb and retinoic acid receptor alpha are mutual antagonists. Blood cells, molecules & diseases. vol 24. issue 2. 1998-11-23. PMID:9714701. |
conversely, v-myb protein interferes with rar alpha transactivation function as well as with retinoic acid-induced apoptosis of hl-60 cells. |
1998-11-23 |
2023-08-12 |
Not clear |
C A Bradham, T Qian, K Streetz, C Trautwein, D A Brenner, J J Lemaster. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Molecular and cellular biology. vol 18. issue 11. 1998-11-23. PMID:9774651. |
in primary rat hepatocytes expressing an ikappab superrepressor, tumor necrosis factor alpha (tnfalpha) induced apoptosis as shown by nuclear morphology, dna ladder formation, and caspase 3 activation. |
1998-11-23 |
2023-08-12 |
rat |
M P Soares, A Muniappan, E Kaczmarek, K Koziak, C J Wrighton, F Steinhäuslin, C Ferran, H Winkler, F H Bach, J Anrathe. Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 9. 1998-11-18. PMID:9794384. |
however, i kappab alpha sensitizes ec to tnf-alpha-mediated apoptosis, presumably by suppressing the induction of the nf-kappab-dependent anti-apoptotic genes a20, a1, manganese superoxide dismutase (mnsod), and cellular inhibitor of apoptosis 2. |
1998-11-18 |
2023-08-12 |
Not clear |
M E Burow, C B Weldon, Y Tang, G L Navar, S Krajewski, J C Reed, T G Hammond, S Clejan, B S Beckma. Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants. Cancer research. vol 58. issue 21. 1998-11-18. PMID:9810003. |
tumor necrosis factor alpha (tnf-alpha) has been shown to both induce apoptosis and inhibit proliferation in mcf-7 cells. |
1998-11-18 |
2023-08-12 |
human |
M A Alexander-Miller, M A Derby, A Sarin, P A Henkart, J A Berzofsk. Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes. The Journal of experimental medicine. vol 188. issue 8. 1998-11-17. PMID:9782116. |
supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor ii-mediated apoptosis of cytotoxic t lymphocytes. |
1998-11-17 |
2023-08-12 |
Not clear |
Z G Wang, D Ruggero, S Ronchetti, S Zhong, M Gaboli, R Rivi, P P Pandolf. PML is essential for multiple apoptotic pathways. Nature genetics. vol 20. issue 3. 1998-11-16. PMID:9806545. |
the pml-rar alpha fusion protein of apl renders haemopoietic progenitor cells resistant to fas-, tnf- and ifn-induced apoptosis with a lack of caspase 3 activation, thus acting as a pml dominant-negative product. |
1998-11-16 |
2023-08-12 |
mouse |
G Chinetti, S Griglio, M Antonucci, I P Torra, P Delerive, Z Majd, J C Fruchart, J Chapman, J Najib, B Stael. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. The Journal of biological chemistry. vol 273. issue 40. 1998-11-12. PMID:9748221. |
activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. |
1998-11-12 |
2023-08-12 |
human |
B Rayet, J A Lopez-Guerrero, J Rommelaere, C Dinsar. Induction of programmed cell death by parvovirus H-1 in U937 cells: connection with the tumor necrosis factor alpha signalling pathway. Journal of virology. vol 72. issue 11. 1998-11-05. PMID:9765434. |
the human promonocytic cell line u937 undergoes apoptosis upon treatment with tumor necrosis factor alpha (tnf-alpha). |
1998-11-05 |
2023-08-12 |
human |