| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R van der Zee, T Murohara, J Passeri, M Kearney, D A Cheresh, J M Isne. Reduced intimal thickening following alpha(v)beta3 blockade is associated with smooth muscle cell apoptosis. Cell adhesion and communication. vol 6. issue 5. 1999-07-09. PMID:10223353. |
this favorable impact on neointimal thickening is associated with apoptosis of activated smcs expressing alpha(v)beta3. |
1999-07-09 |
2023-08-12 |
rabbit |
| J Li, C A Bombeck, S Yang, Y M Kim, T R Billia. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. The Journal of biological chemistry. vol 274. issue 24. 1999-07-06. PMID:10358093. |
we found that both exogenous no as well as endogenously produced no via adenoviral inducible no synthase gene transfer protected hepatocytes from tumor necrosid factor (tnf) alpha plus actinomycin d (tnfalpha/actd)-induced apoptosis. |
1999-07-06 |
2023-08-12 |
Not clear |
| E Petitclerc, S Strömblad, T L von Schalscha, F Mitjans, J Piulats, A M Montgomery, D A Cheresh, P C Brook. Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival. Cancer research. vol 59. issue 11. 1999-06-29. PMID:10363998. |
antagonists of alpha(v)beta3 blocked melanoma growth by inducing tumor apoptosis. |
1999-06-29 |
2023-08-12 |
human |
| J Braess, C Wegendt, M Feuring-Buske, J Riggert, W Kern, W Hiddemann, E Schleye. Leukaemic blasts differ from normal bone marrow mononuclear cells and CD34+ haemopoietic stem cells in their metabolism of cytosine arabinoside. British journal of haematology. vol 105. issue 2. 1999-06-24. PMID:10233409. |
different metabolites of cytosine arabinoside (arac) contribute to its cytotoxicity including incorporation of aractp into dna, the incorporation of araump into rna, inhibition of polymerase alpha and beta (aracmp/ctp), an impairment of repair mechanisms (aractp), alterations of phospholipid metabolism (aracdp-choline), a direct membrane interaction (arac), the alteration of signal transduction pathways (aracdp-choline, aractp) and the induction of apoptosis. |
1999-06-24 |
2023-08-12 |
human |
| J K Chon, A Borkowski, A W Partin, J T Isaacs, S C Jacobs, N Kypriano. Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia. The Journal of urology. vol 161. issue 6. 1999-06-23. PMID:10332490. |
alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia. |
1999-06-23 |
2023-08-12 |
Not clear |
| J K Chon, A Borkowski, A W Partin, J T Isaacs, S C Jacobs, N Kypriano. Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia. The Journal of urology. vol 161. issue 6. 1999-06-23. PMID:10332490. |
recent evidence indicated that an alpha 1 blocker, doxazosin, induces prostate apoptosis in patients with benign prostatic hyperplasia (bph). |
1999-06-23 |
2023-08-12 |
Not clear |
| V N Ivanov, Z Rona. Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. The Journal of biological chemistry. vol 274. issue 20. 1999-06-17. PMID:10318823. |
down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases uvc-induced apoptosis of late-stage melanoma cells. |
1999-06-17 |
2023-08-12 |
human |
| D H Lee, J P Macintyre, G R Taylor, E Wang, R K Plante, S S Tam, B L Pope, C Y La. Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells. The Journal of pharmacology and experimental therapeutics. vol 289. issue 3. 1999-06-15. PMID:10336540. |
we studied the effects of a series of di-aryl-substituted pyrazole nf-kappab inhibitors including tepoxalin on tumor necrosis factor alpha (tnfalpha)-induced apoptosis in murine fibrosarcoma wehi 164 cells. |
1999-06-15 |
2023-08-12 |
Not clear |
| H Marusawa, M Hijikata, T Chiba, K Shimotohn. Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation. Journal of virology. vol 73. issue 6. 1999-06-07. PMID:10233931. |
the effects of hepatitis c virus (hcv) proteins on anti-fas (cd95/apo-1) antibody- and tumor necrosis factor alpha (tnf-alpha)-mediated apoptosis in different human cell lines were investigated by magnetic concentration of cells which transiently produced the exogenous protein. |
1999-06-07 |
2023-08-12 |
human |
| R Goyal, H Qawi, I Ali, S Dar, S Mundle, V Shetty, Y Mativi, K Allampallam, L Lisak, J Loew, P Venugopal, S Gezer, E Robin, S Rifkin, A Raz. Biologic characteristics of patients with hypocellular myelodysplastic syndromes. Leukemia research. vol 23. issue 4. 1999-05-25. PMID:10229321. |
rates of proliferation and apoptosis as well as expression of tumor necrosis factor alpha (tnf-alpha), transforming growth factor beta (tgf-beta) and the number of macrophages were measured in bone marrow (bm) biopsies of 33 patients who presented with hypocellular (cellularity < 30%) myelodysplastic syndromes (mds). |
1999-05-25 |
2023-08-12 |
Not clear |
| S R Kimbal. Eukaryotic initiation factor eIF2. The international journal of biochemistry & cell biology. vol 31. issue 1. 1999-05-17. PMID:10216940. |
phosphorylation of eif2 alpha occurs under a variety of conditions including viral infection, apoptosis, nutrient deprivation, heme-deprivation, and certain stresses. |
1999-05-17 |
2023-08-12 |
Not clear |
| M L Jelachich, C Bramlage, H L Lipto. Differentiation of M1 myeloid precursor cells into macrophages results in binding and infection by Theiler's murine encephalomyelitis virus and apoptosis. Journal of virology. vol 73. issue 4. 1999-05-06. PMID:10074176. |
analysis of bcl-2 protein family expression in undifferentiated and differentiated cells suggests that susceptibility of m1-d cells to apoptosis may be controlled, in part, by expression of the proapoptotic alpha isoform of bax and bak. |
1999-05-06 |
2023-08-12 |
mouse |
| H Y Wang, C P Shelburne, J Zamorano, A E Kelly, J J Ryan, A D Keega. Cutting edge: effects of an allergy-associated mutation in the human IL-4R alpha (Q576R) on human IL-4-induced signal transduction. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 8. 1999-05-06. PMID:10201973. |
to directly test this hypothesis, we analyzed the ability of huil-4r alpha cdna bearing the q576r and y575f mutations to signal tyrosine phosphorylation, dna-binding activity, proliferation, protection from apoptosis, and cd23 induction in response to huil-4 in murine cells. |
1999-05-06 |
2023-08-12 |
human |
| H M Huang, J C Li, Y C Hsieh, H F Yang-Yen, J J Ye. Optimal proliferation of a hematopoietic progenitor cell line requires either costimulation with stem cell factor or increase of receptor expression that can be replaced by overexpression of Bcl-2. Blood. vol 93. issue 8. 1999-05-03. PMID:10194436. |
overexpression of the il-5 receptor alpha subunit (il5ralpha) in tf-1 cells by genetic selection or retroviral infection also resumed optimal proliferation due to correction of the defect in apoptosis suppression. |
1999-05-03 |
2023-08-12 |
Not clear |
| P Rodríguez, J E Viñuela, L Alvarez-Fernández, J Gómez-Márque. Prothymosin alpha antisense oligonucleotides induce apoptosis in HL-60 cells. Cell death and differentiation. vol 6. issue 1. 1999-04-29. PMID:10200541. |
prothymosin alpha antisense oligonucleotides induce apoptosis in hl-60 cells. |
1999-04-29 |
2023-08-12 |
Not clear |
| J Desai, V Holt-Shore, R J Torry, M R Caudle, D S Torr. Signal transduction and biological function of placenta growth factor in primary human trophoblast. Biology of reproduction. vol 60. issue 4. 1999-04-27. PMID:10084962. |
plgf-induced activation of the sapk signaling pathways protected trophoblast from growth factor withdrawal-induced apoptosis, but it did not protect trophoblast from apoptosis induced by the pro-inflammatory cytokines, interferon gamma and tumor necrosis factor alpha. |
1999-04-27 |
2023-08-12 |
human |
| M L Day, X Zhao, C J Vallorosi, M Putzi, C T Powell, C Lin, K C Da. E-cadherin mediates aggregation-dependent survival of prostate and mammary epithelial cells through the retinoblastoma cell cycle control pathway. The Journal of biological chemistry. vol 274. issue 14. 1999-04-27. PMID:10092652. |
pharmacological activation of protein kinase c (pkc) or inducible overexpression and activation of the alpha isozyme of pkc (pkcalpha) resulted in approximately 60% apoptosis of mammary and prostate epithelial cells. |
1999-04-27 |
2023-08-12 |
Not clear |
| S Vasseur, G Vidal Mallo, F Fiedler, H Bödeker, E Cánepa, S Moreno, J L Iovann. Cloning and expression of the human p8, a nuclear protein with mitogenic activity. European journal of biochemistry. vol 259. issue 3. 1999-04-22. PMID:10092851. |
response to tnf alpha and staurosporine-induced apoptosis was not modified by p8 expression. |
1999-04-22 |
2023-08-12 |
human |
| M V Vara Prasad, N Dhanasekara. GTPase deficient mutant of G(alpha13) regulates the expression of Egr-1 through the small GTPase Rho. Oncogene. vol 18. issue 8. 1999-04-22. PMID:10102635. |
expression of the constitutively activated mutant of g(alpha)13 (g(alpha13)ql) increases the expression of egr-1, an immediate-early response gene that is identified to be involved in cell growth, differentiation, and apoptosis. |
1999-04-22 |
2023-08-12 |
Not clear |
| T Horie, K Dobashi, K Iizuka, A Yoshii, Y Shimizu, T Nakazawa, M Mor. Interferon-gamma rescues TNF-alpha-induced apoptosis mediated by up-regulation of TNFR2 on EoL-1 cells. Experimental hematology. vol 27. issue 3. 1999-04-21. PMID:10089914. |
using a human myeloblastic leukemia cell line, eol-1, we investigated the effect of interferon-gamma (ifn-gamma), which differentiates eol-1 into monocyte/macrophage-like cells on fas antigen (fas)- and tumor necrosis factor-alpha (tnf alpha)-induced apoptosis. |
1999-04-21 |
2023-08-12 |
human |