| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Sol, J Le Junter, I Vassias, J M Freyssinier, A Thomas, A F Prigent, B B Rudkin, S Fichelson, F Morine. Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19. Journal of virology. vol 73. issue 10. 1999-10-12. PMID:10482630. |
possible interactions between the ns-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus b19. |
1999-10-12 |
2023-08-12 |
human |
| N Sol, J Le Junter, I Vassias, J M Freyssinier, A Thomas, A F Prigent, B B Rudkin, S Fichelson, F Morine. Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19. Journal of virology. vol 73. issue 10. 1999-10-12. PMID:10482630. |
in contrast, these cells were sensitized to tumor necrosis factor alpha (tnf-alpha)-induced apoptosis. |
1999-10-12 |
2023-08-12 |
human |
| M A Sortino, F Condorelli, C Vancheri, P L Canonic. Tumor necrosis factor-alpha induces apoptosis in immortalized hypothalamic neurons: involvement of ceramide-generating pathways. Endocrinology. vol 140. issue 10. 1999-10-12. PMID:10499544. |
the involvement of acidic sphingomyelinase in tnf alpha action was demonstrated by the partial prevention of ceramide generation, apoptosis, and reduced cell growth by the inhibitor of the acidic sphingomyelinase-generating pathway, d609, whereas the involvement of ceramide was proved by complete prevention of tnf alpha-induced effects by treatment with okadaic acid at concentrations inhibiting ceramide-dependent protein phosphatase. |
1999-10-12 |
2023-08-12 |
Not clear |
| T Masaki, S Miwa, T Sawamura, H Ninomiya, Y Okamot. Subcellular mechanisms of endothelin action in vascular system. European journal of pharmacology. vol 375. issue 1-3. 1999-10-08. PMID:10443571. |
in contrast, endothelin et(b) receptor-mediates differentiation and apoptosis via g(alpha)i coupling. |
1999-10-08 |
2023-08-12 |
Not clear |
| G Feldman. [Apoptosis]. Annales pharmaceutiques francaises. vol 57. issue 4. 1999-10-07. PMID:10472702. |
cell integration of these new findings with regard to apoptosis is illustrated by the description of the apoptotic fas pathway, the mode of action of the proapoptotic cytokine tnf alpha and the analysis of the apoptosis mechanism when dna is damaged and when the p53 gene is overexpressed. |
1999-10-07 |
2023-08-12 |
human |
| J H Uhm, N P Dooley, A P Kyritsis, J S Rao, C L Gladso. Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 6. 1999-09-30. PMID:10389948. |
results of the study were: (a) vn coatings, in a dose-dependent manner, inhibited topoisomerase (topo)-induced apoptosis by up to 50% (optimal coating density, 500 ng/cm2); in contrast, fibronectin (fn), an ecm protein present in abundance in the brain, demonstrated no protection; (b) in a dose-response study, vn clearly conferred a survival advantage (ld50 of topo: on vn, 120 ng/ml; on fn, 35 ng/ml); (c) the protective effect of vn was not due to enhanced cell adhesion or alterations in the cell cycle distribution; (d) both of the classic integrin receptors that bind vn (alpha(v)beta3, alpha(v)beta5) were capable of mediating this protective effect, because ligation of either of the two classic integrins conferred chemoresistance to topo; and (e) chemoresistance observed with vn was associated with an increase in expression of two antiapoptotic proteins, bcl-2 and bcl-x(l), with a consequent increase in the ratios for bcl-2:bax and bcl-x(l):bax. |
1999-09-30 |
2023-08-12 |
human |
| M C Vozenin-Brotons, N Gault, V Sivan, Y Tricaud, B Dubray, K Clough, J M Cosset, J L Lefaix, M Marti. Histopathological and cellular studies of a case of cutaneous radiation syndrome after accidental chronic exposure to a cesium source. Radiation research. vol 152. issue 3. 1999-09-23. PMID:10453095. |
this study was designed for the histopathological, cellular and biochemical characterization of a skin lesion removed surgically from a young male several months after accidental exposure to cesium-137, with an emphasis on expression of transforming growth factor beta1 (tgfb1) and tumor necrosis factor alpha (tnfa) and the occurrence of apoptosis. |
1999-09-23 |
2023-08-12 |
Not clear |
| F M Ruemmele, P Russo, J Beaulieu, S Dionne, E Levy, M J Lentze, E G Seidma. Susceptibility to FAS-induced apoptosis in human nontumoral enterocytes: role of costimulatory factors. Journal of cellular physiology. vol 181. issue 1. 1999-09-23. PMID:10457352. |
in contrast, in the presence of tumor necrosis factor alpha (tnfalpha) and/or interferon gamma (ifngamma), hiec became highly susceptible to fas-induced apoptosis. |
1999-09-23 |
2023-08-12 |
human |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
incubation with tnf alpha (+/- cycloheximide) led to activation of the caspase cascade and was followed by apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
simultaneously, tnf alpha stimulated induction of inos and generation of no.. caspase inhibitors devd-cho, yvad-cmk and yvad-cho effectively inhibited caspase activation and prevented apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
taken together, tnf alpha induces apoptosis in mcf-7 cells by initiating a two-sided effector pathway including inos-induction and activation of caspase 1- and 3-like proteases. |
1999-09-20 |
2023-08-12 |
Not clear |
| E Stüber, A Büschenfeld, A von Freier, T Arendt, U R Fölsc. Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy. Gut. vol 45. issue 2. 1999-09-14. PMID:10403735. |
intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the fasl-fas interaction: effect of pentoxifylline on the development of mucosal atrophy. |
1999-09-14 |
2023-08-12 |
Not clear |
| D L Brassard, E Maxwell, M Malkowski, T L Nagabhushan, C C Kumar, L Armstron. Integrin alpha(v)beta(3)-mediated activation of apoptosis. Experimental cell research. vol 251. issue 1. 1999-09-14. PMID:10438569. |
integrin alpha(v)beta(3)-mediated activation of apoptosis. |
1999-09-14 |
2023-08-12 |
human |
| T Fujihara, H Fujita, K Tsubota, K Saito, K Tsuzaka, T Abe, T Takeuch. Preferential localization of CD8+ alpha E beta 7+ T cells around acinar epithelial cells with apoptosis in patients with Sjögren's syndrome. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 4. 1999-09-09. PMID:10438965. |
preferential localization of cd8+ alpha e beta 7+ t cells around acinar epithelial cells with apoptosis in patients with sjögren's syndrome. |
1999-09-09 |
2023-08-12 |
Not clear |
| T Fujihara, H Fujita, K Tsubota, K Saito, K Tsuzaka, T Abe, T Takeuch. Preferential localization of CD8+ alpha E beta 7+ T cells around acinar epithelial cells with apoptosis in patients with Sjögren's syndrome. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 4. 1999-09-09. PMID:10438965. |
these results suggested that alpha e beta 7 integrin, by interacting with e-cadherin, mediates the adhesion between cd8+ t lymphocytes and acinar epithelial cells in ss and participates in inducing epithelial cell apoptosis, leading to secretory dysfunction of exocrine glands, a hallmark of ss. |
1999-09-09 |
2023-08-12 |
Not clear |
| J Syken, T De-Medina, K Münge. TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 15. 1999-08-23. PMID:10411904. |
expression of htid-1(l) increases apoptosis induced by both the dna-damaging agent mitomycin c and tumor necrosis factor alpha. |
1999-08-23 |
2023-08-12 |
human |
| S Ho, B Winkler-Lowen, D W Morrish, J Dakour, H Li, L J Guilber. The role of Bcl-2 expression in EGF inhibition of TNF-alpha/IFN-gamma-induced villous trophoblast apoptosis. Placenta. vol 20. issue 5-6. 1999-08-20. PMID:10419807. |
the inflammatory cytokines tumour necrosis factor alpha (tnf-alpha) and immune interferon gamma (ifn-gamma) stimulate villous cytotrophoblast apoptosis while epidermal growth factor (egf) protects. |
1999-08-20 |
2023-08-12 |
Not clear |
| S D Mundle, S Reza, A Ali, Y Mativi, V Shetty, P Venugopal, S A Gregory, A Raz. Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403560. |
furthermore, high amounts of tumor necrosis factor alpha (tnf alpha) have previously been correlated with apoptosis in mds marrows. |
1999-08-19 |
2023-08-12 |
Not clear |
| S D Mundle, S Reza, A Ali, Y Mativi, V Shetty, P Venugopal, S A Gregory, A Raz. Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403560. |
the present studies thus identify the downstream effectors of tnf alpha-inducible apoptosis in mds and so also the suppressors of tnf alpha apoptotic signaling. |
1999-08-19 |
2023-08-12 |
Not clear |
| D M Katschinski, H I Robins, M Schad, S Frede, J Fandre. Role of tumor necrosis factor alpha in hyperthermia-induced apoptosis of human leukemia cells. Cancer research. vol 59. issue 14. 1999-08-12. PMID:10416602. |
role of tumor necrosis factor alpha in hyperthermia-induced apoptosis of human leukemia cells. |
1999-08-12 |
2023-08-12 |
human |