| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Ah-Kim, X Zhang, S Islam, J I Sofi, Y Glickberg, C J Malemud, R W Moskowitz, T M Haqq. Tumour necrosis factor alpha enhances the expression of hydroxyl lyase, cytoplasmic antiproteinase-2 and a dual specificity kinase TTK in human chondrocyte-like cells. Cytokine. vol 12. issue 2. 2000-04-19. PMID:10671299. |
tumour necrosis factor alpha (tnf-alpha) is a cytokine with pleiotropic effects on cells ranging from proliferation to apoptosis. |
2000-04-19 |
2023-08-12 |
human |
| A L Dunican, S J Leuenroth, A Ayala, H H Simm. CXC chemokine suppression of polymorphonuclear leukocytes apoptosis and preservation of function is oxidative stress independent. Shock (Augusta, Ga.). vol 13. issue 3. 2000-04-13. PMID:10718383. |
interleukin 8 (il-8) and growth-related oncogene alpha (gro-alpha) delay neutrophil apoptosis, which is thought to be important for the resolution of inflammation. |
2000-04-13 |
2023-08-12 |
Not clear |
| P R Holden, S C Hasmall, N H James, D R West, R D Brindle, F J Gonzalez, J M Peters, R A Robert. Tumour necrosis factor alpha (TNFalpha): role in suppression of apoptosis by the peroxisome proliferator nafenopin. Cellular and molecular biology (Noisy-le-Grand, France). vol 46. issue 1. 2000-04-13. PMID:10726969. |
tumour necrosis factor alpha (tnfalpha): role in suppression of apoptosis by the peroxisome proliferator nafenopin. |
2000-04-13 |
2023-08-12 |
mouse |
| P R Holden, S C Hasmall, N H James, D R West, R D Brindle, F J Gonzalez, J M Peters, R A Robert. Tumour necrosis factor alpha (TNFalpha): role in suppression of apoptosis by the peroxisome proliferator nafenopin. Cellular and molecular biology (Noisy-le-Grand, France). vol 46. issue 1. 2000-04-13. PMID:10726969. |
in hepatocytes isolated from the peroxisome proliferator activated receptor alpha (pparalpha) null mouse, pps are unable to stimulate dna synthesis or to suppress either spontaneous or tgfbeta1-induced apoptosis. |
2000-04-13 |
2023-08-12 |
mouse |
| S A Hube. T cells expressing the gamma delta T cell receptor induce apoptosis in cardiac myocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728379. |
the objective of the present studies is to demonstrate that gamma delta t cells directly induce greater fas-dependent apoptosis of cultured myocytes than t cells expressing the alpha beta tcr. |
2000-04-13 |
2023-08-12 |
mouse |
| W Song, X Lu, Q Fen. Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728381. |
it has been demonstrated that tumor necrosis factor-alpha (tnf alpha) induces apoptosis in cardiac myocytes. |
2000-04-13 |
2023-08-12 |
mouse |
| W Song, X Lu, Q Fen. Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728381. |
in the present study, we hypothesized that tnf alpha induces myocardial apoptosis by induction of inducible nitric oxide synthase (inos). |
2000-04-13 |
2023-08-12 |
mouse |
| K Singh, C Communal, D B Sawyer, W S Colucc. Adrenergic regulation of myocardial apoptosis. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728393. |
likewise, in transgenic mice overexpression of beta 1-ar or g alpha s is associated with myocyte apoptosis and the development of dilated cardiomyopathy. |
2000-04-13 |
2023-08-12 |
mouse |
| T V Byzova, W Kim, R J Midura, E F Plo. Activation of integrin alpha(V)beta(3) regulates cell adhesion and migration to bone sialoprotein. Experimental cell research. vol 254. issue 2. 2000-04-05. PMID:10640428. |
alpha(v)beta(3), a broadly distributed member of the integrin family of adhesion receptors, has been implicated in a variety of physiological and pathophysiological events, including control of bone density, angiogenesis, apoptosis, tumor growth, and metastasis. |
2000-04-05 |
2023-08-12 |
human |
| A G Evstafieva, G A Belov, M Kalkum, N V Chichkova, A A Bogdanov, V I Agol, A B Vartapetia. Prothymosin alpha fragmentation in apoptosis. FEBS letters. vol 467. issue 2-3. 2000-03-31. PMID:10675528. |
prothymosin alpha fragmentation in apoptosis. |
2000-03-31 |
2023-08-12 |
human |
| A G Evstafieva, G A Belov, M Kalkum, N V Chichkova, A A Bogdanov, V I Agol, A B Vartapetia. Prothymosin alpha fragmentation in apoptosis. FEBS letters. vol 467. issue 2-3. 2000-03-31. PMID:10675528. |
we observed fragmentation of an essential proliferation-related human nuclear protein prothymosin alpha in the course of apoptosis induced by various stimuli. |
2000-03-31 |
2023-08-12 |
human |
| H Fujita, I Morita, S Murot. A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. Mediators of inflammation. vol 8. issue 4-5. 2000-03-21. PMID:10704075. |
a possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. |
2000-03-21 |
2023-08-12 |
cattle |
| H Fujita, I Morita, S Murot. A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. Mediators of inflammation. vol 8. issue 4-5. 2000-03-21. PMID:10704075. |
we examined the tumor necrosis factor alpha (tnfalpha)-induced apoptosis of vascular endothelial cells from the standpoint of ion channels. |
2000-03-21 |
2023-08-12 |
cattle |
| H Jo, R Zhang, H Zhang, T A McKinsey, J Shao, R D Beauchamp, D W Ballard, P Lian. NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis. Oncogene. vol 19. issue 7. 2000-03-16. PMID:10702792. |
such clonally isolated cells overexpressing i kappa b alpha super-repressor not only were viable but also exhibited no sign of spontaneous apoptosis. |
2000-03-16 |
2023-08-12 |
rat |
| X Li, Z Darzynkiewic. Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis. Experimental cell research. vol 255. issue 1. 2000-03-14. PMID:10666341. |
the aim of the present study was to reveal cell cycle phase specificity as well as the temporal and sequence relationships of parp cleavage vis-à-vis dna fragmentation in two model systems of apoptosis, one induced by dna damage via cell treatment with camptothecin (cpt) (mitochondria-induced pathway) and another by the cytotoxic ligand tumor necrosis factor alpha (tnf-alpha) (cell surface death receptor pathway). |
2000-03-14 |
2023-08-12 |
Not clear |
| J M Kim, J S Kim, H C Jung, I S Song, C Y Ki. Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble Fas ligands. Scandinavian journal of gastroenterology. vol 35. issue 1. 2000-03-01. PMID:10672833. |
apoptosis of human gastric epithelial cells via caspase-3 activation in response to helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble fas ligands. |
2000-03-01 |
2023-08-12 |
human |
| A Erdreich-Epstein, H Shimada, S Groshen, M Liu, L S Metelitsa, K S Kim, M F Stins, R C Seeger, D L Durde. Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide. Cancer research. vol 60. issue 3. 2000-02-28. PMID:10676658. |
inhibition of the rgd-binding integrins, alpha(v)beta3 and alpha(v)beta5, prevents endothelial cell anchorage and induces endothelial apoptosis, which results in disruption of tumor angiogenesis and inhibition of tumor growth in animal models. |
2000-02-28 |
2023-08-12 |
cattle |
| A Erdreich-Epstein, H Shimada, S Groshen, M Liu, L S Metelitsa, K S Kim, M F Stins, R C Seeger, D L Durde. Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide. Cancer research. vol 60. issue 3. 2000-02-28. PMID:10676658. |
this suggests that ceramide may function in detachment-induced endothelial cell apoptosis, originating from inhibition of vitronectin binding to integrins such as alpha(v)beta3 and alpha(v)beta5. |
2000-02-28 |
2023-08-12 |
cattle |
| R A Roberts, N H James, S C Cosulic. The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis. Hepatology (Baltimore, Md.). vol 31. issue 2. 2000-02-24. PMID:10655266. |
in this study, we have investigated the role of signaling pathways activated by tumor necrosis factor alpha (tnf-alpha) and epidermal growth factor (egf) in the regulation of apoptosis induced by transforming growth factor beta(1) (tgf-beta(1)), because this physiological factor is believed to regulate spontaneous apoptosis in the liver. |
2000-02-24 |
2023-08-12 |
rat |
| M Spitaler, B Wiesenhofer, V Biedermann, T Seppi, J Zimmermann, H Grunicke, J Hofman. The involvement of protein kinase C isoenzymes alpha, epsilon and zeta in the sensitivity to antitumor treatment and apoptosis induction. Anticancer research. vol 19. issue 5B. 2000-02-18. PMID:10628339. |
in order to obtain additional information on the involvement of protein kinase c (pkc) isoenzymes in the resistance of cells to anticancer drugs and in the induction of apoptosis, we employed antisense oligonucleotides to pkc alpha and pkc zeta, cgp 53506, a new inhibitor of pkc alpha, and cells overexpressing pkc alpha, pkc epsilon and pkc zeta. |
2000-02-18 |
2023-08-12 |
Not clear |