| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruili Sun, Yu Zhang, Qingshan Lv, Bei Liu, Miao Jin, Weijia Zhang, Qing He, Minjie Deng, Xueting Liu, Guancheng Li, Yuehui Li, Guohua Zhou, Pingli Xie, Xiumei Xie, Jinyue Hu, Zhaojun Dua. Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha). The Journal of biological chemistry. vol 286. issue 18. 2011-07-01. PMID:21367858. |
toll-like receptor 3 (tlr3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (tap63alpha). |
2011-07-01 |
2023-08-12 |
Not clear |
| Hongxia Li, Xiaoming Li, Xiaoping Gao, Xiuying L. [Induction of apoptosis by tumor necrosis factor receptors 2 transgene in human laryngeal squamous cacinoma in nude mice animal model]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 23. issue 3. 2011-06-30. PMID:19452731. |
to investigate the effect of tumor necrosis factor receptors ii (tnfr ii) in vivo transgene with topical injection of tnf alpha in inducing apoptosis and cell killing of laryngeal squamous carcinoma in nude mice animal model. |
2011-06-30 |
2023-08-12 |
mouse |
| Antonio M Galvao, David W Ramilo, Dariusz J Skarzynski, Karolina Lukasik, Angela Tramontano, Antonio Mollo, Luisa M Mateus, Graca Maria L Ferreira-Dia. Is FAS/Fas ligand system involved in equine corpus luteum functional regression? Biology of reproduction. vol 83. issue 6. 2011-05-27. PMID:20720169. |
the aim of the present work was to determine (i) the presence of the cytokine fasl and its receptor fas in the mare's corpus luteum (cl) throughout the luteal phase, as well as (ii) the influence of fasl alone, or together with the cytokines tumor necrosis factor alpha (tnf) and interferon gamma (ifng), on equine luteal cell production of luteotrophic and luteolytic factors, cell viability, and apoptosis. |
2011-05-27 |
2023-08-12 |
Not clear |
| Hu Xu, Yongwei Yao, Zhaoliang Su, Yunbo Yang, Raymond Kao, Claudio M Martin, Tao Ru. Endogenous HMGB1 contributes to ischemia-reperfusion-induced myocardial apoptosis by potentiating the effect of TNF-α/JNK. American journal of physiology. Heart and circulatory physiology. vol 300. issue 3. 2011-05-26. PMID:21186276. |
endogenous hmgb1 contributes to ischemia-reperfusion-induced myocardial apoptosis by potentiating the effect of tnf-α/jnk. |
2011-05-26 |
2023-08-12 |
Not clear |
| Yasuhide Hori, Kenichiro Ishii, Hideki Kanda, Yoichi Iwamoto, Kohei Nishikawa, Norihito Soga, Hideaki Kise, Kiminobu Arima, Yoshiki Sugimur. Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma. Cancer prevention research (Philadelphia, Pa.). vol 4. issue 1. 2011-04-28. PMID:21205739. |
several studies demonstrated that alpha(1)-adrenoceptor (α(1)-ar) antagonists, therapeutic drugs for benign prostatic hyperplasia, have growth inhibitory effects on human prostate cancer (pca) cells through induction of apoptosis or g(1) cell-cycle arrest. |
2011-04-28 |
2023-08-12 |
human |
| S M Kim, S Y Yoon, J E Choi, J S Park, J M Choi, T Nguyen, D H Ki. Activation of eukaryotic initiation factor-2 α-kinases in okadaic acid-treated neurons. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600673. |
activating transcription factor (atf4) which induces apoptosis in response to eif2 alpha phosphorylation was increased and translocated to nuclei in oa-treated neurons. |
2011-04-18 |
2023-08-12 |
rat |
| Farrokh K Asadi, Subhash C Kukreja, Brigitte Boyer, Ana-Maria Valess, James L Coo. E1A oncogene expression inhibits PTHrP P3 promoter activity and sensitizes human prostate cancer cells to TNF-induced apoptosis. International urology and nephrology. vol 42. issue 4. 2011-04-04. PMID:20082139. |
expression of the adenovirus e1a oncogene repressed pthrp promoter and mrna expression in human pc-3 prostate cancer cells and increased the caspase 3 activation and sensitivity of these cells to apoptosis triggered by tumor necrosis factor alpha. |
2011-04-04 |
2023-08-12 |
human |
| Arabinda Das, Joshua A Smith, Cameron Gibson, Abhay K Varma, Swapan K Ray, Naren L Bani. Estrogen receptor agonists and estrogen attenuate TNF-α-induced apoptosis in VSC4.1 motoneurons. The Journal of endocrinology. vol 208. issue 2. 2011-02-17. PMID:21068071. |
we tested whether 1,3,5-tris (4-hydroxyphenyl)-4-propyl-1h-pyrazole (ppt) (est receptor alpha (erα) agonist), 2,3-bis (4-hydroxyphenyl) propionitrile (dpn) (est receptor beta (erβ) agonist), or est itself would prevent apoptosis in vsc4.1 motoneurons following exposure to tnf-α. |
2011-02-17 |
2023-08-12 |
Not clear |
| June-Won Cheong, Yoo Hong Min, Ju In Eom, Soo Jeong Kim, Hoi Kyung Jeung, Jin Seok Ki. Inhibition of CK2{alpha} and PI3K/Akt synergistically induces apoptosis of CD34+CD38- leukaemia cells while sparing haematopoietic stem cells. Anticancer research. vol 30. issue 11. 2011-01-18. PMID:21115916. |
inhibition of ck2{alpha} and pi3k/akt synergistically induces apoptosis of cd34+cd38- leukaemia cells while sparing haematopoietic stem cells. |
2011-01-18 |
2023-08-12 |
Not clear |
| M Ehrenschwender, D Siegmund, A Wicovsky, M Kracht, O Dittrich-Breiholz, V Spindler, J Waschke, H Kalthoff, A Trauzold, H Wajan. Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation. Cell death and differentiation. vol 17. issue 9. 2011-01-13. PMID:20379197. |
constitutively active pi3k catalytic subunit alpha (pik3ca) interfered with apoptosis induction downstream of death receptor-signaling complex formation allowing robust caspase-8 activation without triggering the execution steps of apoptosis. |
2011-01-13 |
2023-08-12 |
Not clear |
| Nurit Keinan, Dalia Tyomkin, Varda Shoshan-Barmat. Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. Molecular and cellular biology. vol 30. issue 24. 2011-01-13. PMID:20937774. |
vdac oligomerization was induced in all cell types and with all apoptosis inducers used, including staurosporine, curcumin, as(2)o(3), etoposide, cisplatin, selenite, tumor necrosis factor alpha (tnf-α), h(2)o(2), and uv irradiation, all acting through different mechanisms yet all involving mitochondria. |
2011-01-13 |
2023-08-12 |
Not clear |
| Josef Krieglstein, Tobias Kewitz, Uwe Kirchhefer, Oliver Hofnagel, Gabriele Weissen-Plenz, Michael Reinbold, Susanne Klump. Damage of guinea pig heart and arteries by a trioleate-enriched diet and of cultured cardiomyocytes by oleic acid. PloS one. vol 5. issue 3. 2011-01-11. PMID:20221399. |
mono-unsaturated fatty acids (mufas) like oleic acid have been shown to cause apoptosis of cultured endothelial cells by activating protein phosphatase type 2c alpha and beta (pp2c). |
2011-01-11 |
2023-08-12 |
Not clear |
| Pronobesh Chattopadhyay, Arun Kumar Wah. Inhibition by folic acid of tumor necrosis factor alpha and apoptosis following normothermic ischemia-reperfusion. Arzneimittel-Forschung. vol 60. issue 10. 2010-12-30. PMID:21125813. |
inhibition by folic acid of tumor necrosis factor alpha and apoptosis following normothermic ischemia-reperfusion. |
2010-12-30 |
2023-08-12 |
rat |
| Nicole A Atchison, Wei Fan, Klearchos K Papas, Bernhard J Hering, Michael Tsapatsis, Efrosini Kokkol. Binding of the fibronectin-mimetic peptide, PR_b, to alpha5beta1 on pig islet cells increases fibronectin production and facilitates internalization of PR_b functionalized liposomes. Langmuir : the ACS journal of surfaces and colloids. vol 26. issue 17. 2010-12-27. PMID:20704278. |
fibronectin production stimulated through alpha(5)beta(1) pr_b binding may decrease apoptosis and therefore increase islet viability in culture. |
2010-12-27 |
2023-08-12 |
human |
| Chiarella Bozzo, Francesca Graziola, Annalisa Chiocchetti, Pier Luigi Canonic. Estrogen and beta-amyloid toxicity: role of integrin and PI3-K. Molecular and cellular neurosciences. vol 45. issue 2. 2010-12-14. PMID:20538057. |
estrogen and beta-amyloid toxicity: role of integrin and pi3-k. beta-amyloid peptide (betaap) induces apoptosis and down-regulation of alpha(1)beta(1) integrin in neuronal cells, indicating a relationship between betaap neurotoxicity and modulation of integrin expression. |
2010-12-14 |
2023-08-12 |
human |
| Chiung-Wen Pai, Yau-Hung Che. Transgenic expression of prothymosin alpha on zebrafish epidermal cells promotes proliferation and attenuates UVB-induced apoptosis. Transgenic research. vol 19. issue 4. 2010-12-02. PMID:20012190. |
transgenic expression of prothymosin alpha on zebrafish epidermal cells promotes proliferation and attenuates uvb-induced apoptosis. |
2010-12-02 |
2023-08-12 |
zebrafish |
| Yaling Han, Guangzhe Wu, Jie Deng, Jie Tao, Liang Guo, Xiaoxiang Tian, Jian Kang, Xiaolin Zhang, Chenghui Ya. Cellular repressor of E1A-stimulated genes inhibits human vascular smooth muscle cell apoptosis via blocking P38/JNK MAP kinase activation. Journal of molecular and cellular cardiology. vol 48. issue 6. 2010-11-16. PMID:20060003. |
more importantly, creg-dw-induced vsmc apoptosis was blocked by the p38-specific inhibitor sb203580 or by overexpression of a dominant-negative p38 alpha (p38 alpha agf). |
2010-11-16 |
2023-08-12 |
human |
| Alessio Paone, Roberta Galli, Chiara Gabellini, Dmitriy Lukashev, Donatella Starace, Agnes Gorlach, Paola De Cesaris, Elio Ziparo, Donatella Del Bufalo, Michail V Sitkovsky, Antonio Filippini, Anna Ricciol. Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. Neoplasia (New York, N.Y.). vol 12. issue 7. 2010-11-05. PMID:20651983. |
toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. |
2010-11-05 |
2023-08-12 |
Not clear |
| Alessio Paone, Roberta Galli, Chiara Gabellini, Dmitriy Lukashev, Donatella Starace, Agnes Gorlach, Paola De Cesaris, Elio Ziparo, Donatella Del Bufalo, Michail V Sitkovsky, Antonio Filippini, Anna Ricciol. Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. Neoplasia (New York, N.Y.). vol 12. issue 7. 2010-11-05. PMID:20651983. |
here we describe a novel protumor machinery triggered by tlr3 activation in pc3 cells consisting of increased expression of the specific i.3 isoform of hif-1 alpha and nuclear accumulation of hif-1 complex in normoxia, resulting in reduced apoptosis and in secretion of functional vascular endothelial growth factor (vegf). |
2010-11-05 |
2023-08-12 |
Not clear |
| Alessio Paone, Roberta Galli, Chiara Gabellini, Dmitriy Lukashev, Donatella Starace, Agnes Gorlach, Paola De Cesaris, Elio Ziparo, Donatella Del Bufalo, Michail V Sitkovsky, Antonio Filippini, Anna Ricciol. Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. Neoplasia (New York, N.Y.). vol 12. issue 7. 2010-11-05. PMID:20651983. |
however, the transfection of i.3 isoform of hif-1 alpha in lncap cells allows poly(i:c)-induced hif-1 activation, resulting in apoptosis protection and vegf secretion. |
2010-11-05 |
2023-08-12 |
Not clear |