| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kuanfeng Xu, Ying Zhou, Wen Qiu, Xin Liu, Mei Xia, Lisha Liu, Xiaomei Liu, Dan Zhao, Yingwei Wan. Activating transcription factor 3 (ATF3) promotes sublytic C5b-9-induced glomerular mesangial cells apoptosis through up-regulation of Gadd45α and KLF6 gene expression. Immunobiology. vol 216. issue 8. 2011-11-21. PMID:21396734. |
in this study, the data showed that the expression of atf3, growth arrest and dna damage-45 alpha (gadd45α), krüppel-like factor 6 (klf6) and proliferating cell nuclear antigen (pcna) in the gmcs in response to sublytic c5b-9 stimulation for the indicated time was significantly increased, and atf3 expression could lead to gmcs apoptosis through up-regulation of gadd45α and klf6, but not up-regulation of pcna. |
2011-11-21 |
2023-08-12 |
rat |
| Jonathan H Seideman, Branka Stancevic, Jimmy A Rotolo, Michael R McDevitt, Roger W Howell, Richard N Kolesnick, David A Scheinber. Alpha particles induce apoptosis through the sphingomyelin pathway. Radiation research. vol 176. issue 4. 2011-11-15. PMID:21631289. |
alpha particles induce apoptosis through the sphingomyelin pathway. |
2011-11-15 |
2023-08-12 |
Not clear |
| Sânia Alves dos Santos, Dahir Ramos de Andrade Júnior, Dahir Ramos de Andrad. TNF-α production and apoptosis in hepatocytes after Listeria monocytogenes and Salmonella Typhimurium invasion. Revista do Instituto de Medicina Tropical de Sao Paulo. vol 53. issue 2. 2011-10-20. PMID:21537759. |
invasion of hepatocytes by listeria monocytogenes (lm) and salmonella typhimurium (st) can stimulate tumor necrosis factor alpha (tnf-α) release and induce apoptosis. |
2011-10-20 |
2023-08-12 |
Not clear |
| Ishraq Hussain, Ikbal Fathallah, Rosita Accardi, Jiping Yue, Djamel Saidj, Ruchi Shukla, Uzma Hasan, Tarik Gheit, Yamei Niu, Massimo Tommasino, Bakary S Syll. NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis. Journal of virology. vol 85. issue 17. 2011-10-04. PMID:21715489. |
nf-kappab protects human papillomavirus type 38 e6/e7-immortalized human keratinocytes against tumor necrosis factor alpha and uv-mediated apoptosis. |
2011-10-04 |
2023-08-12 |
human |
| Ishraq Hussain, Ikbal Fathallah, Rosita Accardi, Jiping Yue, Djamel Saidj, Ruchi Shukla, Uzma Hasan, Tarik Gheit, Yamei Niu, Massimo Tommasino, Bakary S Syll. NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis. Journal of virology. vol 85. issue 17. 2011-10-04. PMID:21715489. |
in this study, we showed that hpv38 e6 and e7 activate nf-κb and that inhibition of the pathway with the iκbα superrepressor sensitizes hpv38e6e7-immortalized human keratinocytes to tumor necrosis factor alpha (tnf-α)- and uvb radiation-mediated apoptosis. |
2011-10-04 |
2023-08-12 |
human |
| Dan Ji, Tengku A Kamalden, Susana del Olmo-Aguado, Neville N Osborn. Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms. Apoptosis : an international journal on programmed cell death. vol 16. issue 4. 2011-09-30. PMID:21279443. |
moreover, light caused an activation of the apoptosis inducing factor (aif), c-jun, jnk and ho-1, but it did not affect alpha fodrin or caspase-3. |
2011-09-30 |
2023-08-12 |
Not clear |
| Sandra Hervas-Stubbs, Jose Luis Perez-Gracia, Ana Rouzaut, Miguel F Sanmamed, Agnes Le Bon, Ignacio Meler. Direct effects of type I interferons on cells of the immune system. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 17. issue 9. 2011-09-15. PMID:21372217. |
type i interferons (ifn-i) are well-known inducers of tumor cell apoptosis and antiangiogenesis via signaling through a common receptor interferon alpha receptor (ifnar). |
2011-09-15 |
2023-08-12 |
mouse |
| Larissa Dyugovskaya, Andrey Polyakov, Darrell Ginsberg, Peretz Lavie, Lena Lavi. Molecular pathways of spontaneous and TNF-{alpha}-mediated neutrophil apoptosis under intermittent hypoxia. American journal of respiratory cell and molecular biology. vol 45. issue 1. 2011-09-08. PMID:20870895. |
molecular pathways of spontaneous and tnf-{alpha}-mediated neutrophil apoptosis under intermittent hypoxia. |
2011-09-08 |
2023-08-12 |
Not clear |
| R Puff, P Dames, M Weise, B Göke, J Seissler, K G Parhofer, A Lechne. Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 43. issue 5. 2011-08-25. PMID:21412687. |
body weight, fasting blood glucose, plasma insulin, homa-ir, alpha cell mass, beta cell mass, proliferation and apoptosis were measured. |
2011-08-25 |
2023-08-12 |
mouse |
| Wei Zhang, Dao-xin Wan. [Study of regulatory effect of insulin on expression of epithelial sodium channel alpha subunit in A549 cells]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 22. issue 7. 2011-08-15. PMID:20663296. |
to observe the effects of insulin on the expression of epithelial sodium channel alpha subunit (enac-alpha) in human pulmonary adenocarcinoma cell line (a549 cells) and its impact on apoptosis of the cells. |
2011-08-15 |
2023-08-12 |
human |
| Paola I Ingaramo, María T Ronco, Daniel E A Francés, Juan A Monti, Gerardo B Pisani, María P Ceballos, Mónica Galleano, María C Carrillo, Cristina E Carnoval. Tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus. Molecular immunology. vol 48. issue 12-13. 2011-08-10. PMID:21481476. |
tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus. |
2011-08-10 |
2023-08-12 |
rat |
| H H Cheung, M St Jean, S T Beug, R Lejmi-Mrad, E LaCasse, S D Baird, D F Stojdl, R A Screaton, R G Kornelu. SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds. Cell death & disease. vol 2. 2011-08-05. PMID:21490678. |
smac mimetic compounds (smcs) are experimental small molecules that induce tumour necrosis factor alpha (tnfα)-dependent cancer cell death by targeting the inhibitor of apoptosis proteins. |
2011-08-05 |
2023-08-12 |
Not clear |
| Claudio Contaldo, Nicole Lindenblatt, Ahmed Elsherbiny, Dominik C Högger, Meisam Khorrami Borozadi, Sebastian T Vetter, Karl S Lang, Alexander E Handschin, Pietro Giovanol. Erythropoietin requires endothelial nitric oxide synthase to counteract TNF-[alpha]-induced microcirculatory dysfunction in murine striated muscle. Shock (Augusta, Ga.). vol 35. issue 3. 2011-08-04. PMID:20926979. |
tnf-[alpha]-associated leukocyte activation, perfusion failure, and apoptosis were substantially attenuated in epo-pretreated wt mice, which was accompanied by marked reduction of perivascular infiltration with f4/80-stained macrophages. |
2011-08-04 |
2023-08-12 |
mouse |
| Yi-yang Wang, Hong-mei Li, Hua-dong Wang, Xue-mei Peng, Yan-ping Wang, Da-xiang Lu, Ren-bin Qi, Chao-feng Hu, Jian-wei Jian. Pretreatment with berberine and yohimbine protects against LPS-induced myocardial dysfunction via inhibition of cardiac I-[kappa]B[alpha] phosphorylation and apoptosis in mice. Shock (Augusta, Ga.). vol 35. issue 3. 2011-08-04. PMID:20926983. |
pretreatment with berberine and yohimbine protects against lps-induced myocardial dysfunction via inhibition of cardiac i-[kappa]b[alpha] phosphorylation and apoptosis in mice. |
2011-08-04 |
2023-08-12 |
mouse |
| Yi-yang Wang, Hong-mei Li, Hua-dong Wang, Xue-mei Peng, Yan-ping Wang, Da-xiang Lu, Ren-bin Qi, Chao-feng Hu, Jian-wei Jian. Pretreatment with berberine and yohimbine protects against LPS-induced myocardial dysfunction via inhibition of cardiac I-[kappa]B[alpha] phosphorylation and apoptosis in mice. Shock (Augusta, Ga.). vol 35. issue 3. 2011-08-04. PMID:20926983. |
lps-provoked cardiac apoptosis, i-[kappa]b[alpha] phosphorylation, il-1[beta], tnf-[alpha], and no production were attenuated by pretreatment with ber and/or yohimbine, whereas cardiac toll-like receptor 4 mrna expression, malondialdehyde content, and superoxide dismutase activity were not affected. |
2011-08-04 |
2023-08-12 |
mouse |
| Yi-yang Wang, Hong-mei Li, Hua-dong Wang, Xue-mei Peng, Yan-ping Wang, Da-xiang Lu, Ren-bin Qi, Chao-feng Hu, Jian-wei Jian. Pretreatment with berberine and yohimbine protects against LPS-induced myocardial dysfunction via inhibition of cardiac I-[kappa]B[alpha] phosphorylation and apoptosis in mice. Shock (Augusta, Ga.). vol 35. issue 3. 2011-08-04. PMID:20926983. |
these data demonstrate for the first time that pretreatment with ber and/or yohimbine prevents lps-induced myocardial dysfunction in mice through inhibiting myocardial apoptosis, cardiac i-[kappa]b[alpha] phosphorylation, and tnf-[alpha], il-1[beta], and no production, suggesting that activation of [alpha]2-adrenergic receptor in vivo may be responsible at least in part for lps-induced cardiac dysfunction, and ber in combination with yohimbine may be a potential agent for preventing cardiac dysfunction during sepsis. |
2011-08-04 |
2023-08-12 |
mouse |
| Balindiwe J N Sishi, Anna-Mart Engelbrech. Tumor necrosis factor alpha (TNF-α) inactivates the PI3-kinase/PKB pathway and induces atrophy and apoptosis in L6 myotubes. Cytokine. vol 54. issue 2. 2011-07-29. PMID:21300557. |
tumor necrosis factor alpha (tnf-α) inactivates the pi3-kinase/pkb pathway and induces atrophy and apoptosis in l6 myotubes. |
2011-07-29 |
2023-08-12 |
Not clear |
| Gaurav Swarnkar, Kunal Sharan, Jawed A Siddiqui, Bandana Chakravarti, Preeti Rawat, Manmeet Kumar, Kamal R Arya, Rakesh Maurya, Naibedya Chattopadhya. A novel flavonoid isolated from the steam-bark of Ulmus wallichiana planchon stimulates osteoblast function and inhibits osteoclast and adipocyte differentiation. European journal of pharmacology. vol 658. issue 2-3. 2011-07-25. PMID:21376034. |
additionally, in 3t3-l1 preadipocytes, ag decreased the expression of genes involved in adipogenesis, including peroxisome proliferator-activated receptor gamma (pparγ), sterol regulatory element binding protein (srebp) and ccaat/enhancer-binding protein alpha (cebp/α), and induced apoptosis of differentiated adipocytes. |
2011-07-25 |
2023-08-12 |
mouse |
| Chih-Chiun Chen, Lester F La. Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines. Journal of cell communication and signaling. vol 4. issue 1. 2011-07-14. PMID:19898959. |
further, knockin mice that express an alpha(6)beta(1)-hspg-binding defective ccn1 are blunted in tnfalpha- and fas-mediated apoptosis, indicating that ccn1 is a physiologic regulator of these processes. |
2011-07-14 |
2023-08-12 |
mouse |
| Guilherme F Silveira, Florencia Meyer, Adriana Delfraro, Ana Luiza P Mosimann, Norma Coluchi, Cyntia Vasquez, Christian M Probst, André Báfica, Juliano Bordignon, Claudia N Duarte Dos Santo. Dengue virus type 3 isolated from a fatal case with visceral complications induces enhanced proinflammatory responses and apoptosis of human dendritic cells. Journal of virology. vol 85. issue 11. 2011-07-13. PMID:21450836. |
the observed phenotype was due to viral replication, and tumor necrosis factor alpha (tnf-α) appears to exert a protective effect on virus-induced mddc apoptosis. |
2011-07-13 |
2023-08-12 |
human |