| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sally Purdom, Qin M Che. Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts. The Journal of pharmacology and experimental therapeutics. vol 312. issue 3. 2005-04-05. PMID:15574683. |
mild doses of oxidative stress in the heart correlate with the induction of apoptosis or hypertrophy in cardiomyocytes (cmcs) and fibrosis or proliferation of fibroblasts. |
2005-04-05 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsu. Novel pathophysiological insight and treatment strategies for heart failure--lessons from mice and patients--. Circulation journal : official journal of the Japanese Circulation Society. vol 68. issue 12. 2005-03-29. PMID:15564690. |
oxidative stress causes myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases, all of which result in myocardial remodeling and failure. |
2005-03-29 |
2023-08-12 |
mouse |
| Douglas G Johns, Zhaohui Ao, Diane Naselsky, Christopher L Herold, Kristeen Maniscalco, Lea Sarov-Blat, Klaudia Steplewski, Nambi Aiyar, Stephen A Dougla. Urotensin-II-mediated cardiomyocyte hypertrophy: effect of receptor antagonism and role of inflammatory mediators. Naunyn-Schmiedeberg's archives of pharmacology. vol 370. issue 4. 2005-03-23. PMID:15549273. |
u-ii did not affect cell proliferation or apoptosis, indicating that u-ii is more hypertrophic than apoptotic or hyperplastic in cardiomyocytes. |
2005-03-23 |
2023-08-12 |
rat |
| Erik Kern Harrington, Leif E Lunsford, Kathy K H Svobod. Chondrocyte terminal differentiation, apoptosis, and type X collagen expression are downregulated by parathyroid hormone. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. vol 281. issue 2. 2005-03-17. PMID:15515174. |
in addition, pth increased chondrocyte cell diameter in prehypertrophic and proliferative regions while decreasing chondrocyte apoptosis in the hypertrophic zone. |
2005-03-17 |
2023-08-12 |
Not clear |
| Kazunori Kashiwase, Yoshiharu Higuchi, Shinichi Hirotani, Osamu Yamaguchi, Shungo Hikoso, Toshihiro Takeda, Tetsuya Watanabe, Masayuki Taniike, Atsuko Nakai, Ikuko Tsujimoto, Yasushi Matsumura, Hikaru Ueno, Kazuhiko Nishida, Masatsugu Hori, Kinya Ots. CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy. Biochemical and biophysical research communications. vol 327. issue 1. 2005-03-11. PMID:15629441. |
we previously showed that the activation of apoptosis signal-regulating kinase 1 (ask1) or nf-kappab is sufficient for cardiomyocyte hypertrophy. |
2005-03-11 |
2023-08-12 |
Not clear |
| Donald S Silverberg, Dov Wexler, Adrian Iain. The role of anemia in the progression of congestive heart failure. Is there a place for erythropoietin and intravenous iron? Journal of nephrology. vol 17. issue 6. 2005-03-08. PMID:15593047. |
long-standing anemia of any cause can cause left ventricular hypertrophy (lvh), which can lead to cardiac cell death through apoptosis and worsen the chf. |
2005-03-08 |
2023-08-12 |
Not clear |
| Mehran Mandegar, Yuan-Cheng B Fung, Wei Huang, Carmelle V Remillard, Lewis J Rubin, Jason X-J Yua. Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension. Microvascular research. vol 68. issue 2. 2005-03-07. PMID:15313118. |
vascular remodeling is characterized largely by medial hypertrophy due to enhanced vascular smooth muscle cell proliferation or attenuated apoptosis and to endothelial cell over-proliferation, which can result in lumen obliteration. |
2005-03-07 |
2023-08-12 |
Not clear |
| Shant Der Sarkissian, Eve-Lyne Marchand, David Duguay, Denis deBloi. Synergistic interaction between enalapril, L-arginine and tetrahydrobiopterin in smooth muscle cell apoptosis and aortic remodeling induction in SHR. British journal of pharmacology. vol 142. issue 5. 2005-02-28. PMID:15197102. |
smooth muscle cell (smc) apoptosis occurs at the onset of enalapril-induced regression of aortic hypertrophy in shr. |
2005-02-28 |
2023-08-12 |
Not clear |
| Shant Der Sarkissian, Eve-Lyne Marchand, David Duguay, Denis deBloi. Synergistic interaction between enalapril, L-arginine and tetrahydrobiopterin in smooth muscle cell apoptosis and aortic remodeling induction in SHR. British journal of pharmacology. vol 142. issue 5. 2005-02-28. PMID:15197102. |
the combination of lb with ena for 1 week, however, was additive for the reduction of smc proliferation, and synergistic for the induction of apoptosis and regression of vascular hypertrophy. |
2005-02-28 |
2023-08-12 |
Not clear |
| Parco M Siu, Emidio E Pistilli, David C Butler, Stephen E Alwa. Aging influences cellular and molecular responses of apoptosis to skeletal muscle unloading. American journal of physiology. Cell physiology. vol 288. issue 2. 2005-02-22. PMID:15483226. |
in this study we examined apoptosis and apoptotic regulatory factor responses to muscle atrophy induced via limb unloading following loading-induced hypertrophy. |
2005-02-22 |
2023-08-12 |
Not clear |
| Michiel W M Knaapen, Pamela Somers, Hilde Bortier, Guido R Y De Meyer, Mark M Kock. Smooth muscle cell hypertrophy in varicose veins is associated with expression of estrogen receptor-beta. Journal of vascular research. vol 42. issue 1. 2005-02-22. PMID:15604599. |
this study examined whether the changes that occur in varicose veins are associated with smooth muscle cell (smc) hypertrophy, cellular proliferation or apoptosis. |
2005-02-22 |
2023-08-12 |
human |
| Avraam Ploumis, Maria-Eleni Manthou, Elpida-Niki Emmanouil-Nikolousi, Sofia Androudi, Androudi Sofia, Anastasios Christodoulo. Animal model of chondrocyte apoptosis in the epiphyseal cartilage of the neonatal bone. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. vol 9. issue 5. 2005-02-10. PMID:15449125. |
apoptosis in the zone of hypertrophic cartilage played the most important role in the growth plate's homeostasis. |
2005-02-10 |
2023-08-12 |
rat |
| Ken-ichiro Okada, Tetsuo Minamino, Yoshitane Tsukamoto, Yulin Liao, Osamu Tsukamoto, Seiji Takashima, Akio Hirata, Masashi Fujita, Yoko Nagamachi, Takeshi Nakatani, Chikao Yutani, Kentaro Ozawa, Satoshi Ogawa, Hitonobu Tomoike, Masatsugu Hori, Masafumi Kitakaz. Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation. vol 110. issue 6. 2005-02-08. PMID:15289376. |
prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. |
2005-02-08 |
2023-08-12 |
Not clear |
| Ernest Adeghat. Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: a short review. Molecular and cellular biochemistry. vol 261. issue 1-2. 2005-02-08. PMID:15362503. |
diabetes mellitus induces abnormal pathological findings including cell hypertrophy, neuropathy, interstitial fibrosis, myocytolysis and apoptosis and lipid deposits in the heart. |
2005-02-08 |
2023-08-12 |
human |
| Maurice J B van den Hoff, Ronald H Lekanne Deprez, Jan M Ruijter, Piet A J de Boer, Sabina Tesink-Taekema, Anita A Buffing, Wouter H Lamers, Antoon F M Moorma. Increased cardiac workload by closure of the ductus arteriosus leads to hypertrophy and apoptosis rather than to hyperplasia in the late fetal period. Naunyn-Schmiedeberg's archives of pharmacology. vol 370. issue 3. 2005-02-01. PMID:15340773. |
increased cardiac workload by closure of the ductus arteriosus leads to hypertrophy and apoptosis rather than to hyperplasia in the late fetal period. |
2005-02-01 |
2023-08-12 |
rat |
| Maurice J B van den Hoff, Ronald H Lekanne Deprez, Jan M Ruijter, Piet A J de Boer, Sabina Tesink-Taekema, Anita A Buffing, Wouter H Lamers, Antoon F M Moorma. Increased cardiac workload by closure of the ductus arteriosus leads to hypertrophy and apoptosis rather than to hyperplasia in the late fetal period. Naunyn-Schmiedeberg's archives of pharmacology. vol 370. issue 3. 2005-02-01. PMID:15340773. |
however, this hyperplastic growth is abrogated by a subsequent burst in apoptosis and followed by a hypertrophic response as based on a decrease in dna and increase in both rna and protein concentration. |
2005-02-01 |
2023-08-12 |
rat |
| Maria V Kim, Alim S Seit-Nebi, Nikolai B Guse. The problem of protein kinase activity of small heat shock protein Hsp22 (H11 or HspB8). Biochemical and biophysical research communications. vol 325. issue 3. 2005-01-18. PMID:15541337. |
the recently described protein denoted h11, hsp22 or hspb8 seems to participate in regulation of proliferation, apoptosis, and cardiac hypertrophy. |
2005-01-18 |
2023-08-12 |
Not clear |
| Rama Garimella, Xiahong Bi, Nancy Camacho, Joseph B Sipe, H Clarke Anderso. Primary culture of rat growth plate chondrocytes: an in vitro model of growth plate histotype, matrix vesicle biogenesis and mineralization. Bone. vol 34. issue 6. 2005-01-14. PMID:15193542. |
chondrocytes of growth plate undergo proliferation, maturation, hypertrophy, matrix vesicle (mv) biogenesis and programmed cell death (pcd, apoptosis). |
2005-01-14 |
2023-08-12 |
rat |
| Pål Aukrust, Arne Yndestad, Jan Kristian Damås, Lars Gullesta. Inflammation and chronic heart failure-potential therapeutic role of intravenous immunoglobulin. Autoimmunity reviews. vol 3. issue 3. 2005-01-13. PMID:15110235. |
accumulating evidence indicates that inflammatory cytokines play a pathogenic role in congestive heart failure (chf) by influencing heart contractility, inducing hypertrophy and promoting apoptosis or fibrosis, contributing to the continuous myocardial remodelling process. |
2005-01-13 |
2023-08-12 |
Not clear |
| Xueyan Zheng, Danyi Zhou, Chun Y Seow, Tony R Ba. Cardiotrophin-1 alters airway smooth muscle structure and mechanical properties in airway explants. American journal of physiology. Lung cellular and molecular physiology. vol 287. issue 6. 2005-01-12. PMID:15273080. |
induction of hypertrophy and inhibition of apoptosis may be important mechanisms contributing to increased airway smooth muscle (asm) mass in asthma. |
2005-01-12 |
2023-08-12 |
human |