| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomais Markou, Eleftheria Barlaka, Monica Bartucci, Antigone Lazo. Signal transduction pathways through cytoprotective, apoptotic and hypertrophic stimuli: a comparative study in adult cardiac myocytes. Cell biochemistry and function. vol 29. issue 6. 2011-12-01. PMID:21751224. |
however, the distinction between signalling pathways originally believed to be specific for either hypertrophy, apoptosis or cell survival is fading. |
2011-12-01 |
2023-08-12 |
rat |
| Thomais Markou, Eleftheria Barlaka, Monica Bartucci, Antigone Lazo. Signal transduction pathways through cytoprotective, apoptotic and hypertrophic stimuli: a comparative study in adult cardiac myocytes. Cell biochemistry and function. vol 29. issue 6. 2011-12-01. PMID:21751224. |
whether they promote hypertrophy, cell survival or apoptosis. |
2011-12-01 |
2023-08-12 |
rat |
| Hong-Shan Guan, Hai-Juan Shangguan, Zhuo Shang, Long Yang, Xian-Ming Meng, Shu-Bin Qia. Endoplasmic reticulum stress caused by left ventricular hypertrophy in rats: effects of telmisartan. The American journal of the medical sciences. vol 342. issue 4. 2011-11-08. PMID:21642821. |
although cardiomyocytes apoptosis contributes to the transition from left ventricular hypertrophy (lvh) to heart failure, it is unknown whether er stress participates in the pathologic process. |
2011-11-08 |
2023-08-12 |
rat |
| J Eduardo Rame, Lili A Barouch, Michael N Sack, Edward G Lynn, Mones Abu-Asab, Maria Tsokos, Steven J Kern, Jennifer J Barb, Peter J Munson, Marc K Halushka, Karen L Miller, Karen Fox-Talbot, Jianhua Zhang, Joshua M Hare, Michael A Solomon, Robert L Danne. Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling. Physiological genomics. vol 43. issue 12. 2011-11-04. PMID:21427359. |
obese, leptin-deficient mice develop left ventricular (lv) hypertrophy and myocardial steatosis with increased apoptosis and decreased longevity. |
2011-11-04 |
2023-08-12 |
mouse |
| Anna Idelevich, Michael Kerschnitzki, Ron Shahar, Efrat Monsonego-Orna. 1,25(OH)2D3 alters growth plate maturation and bone architecture in young rats with normal renal function. PloS one. vol 6. issue 6. 2011-11-02. PMID:21695192. |
concomitant with altered chondrocyte maturation, 1,25(oh)(2)d(3) increased chondrocyte proliferation and apoptosis in terminal hypertrophic cells. |
2011-11-02 |
2023-08-12 |
rat |
| Morel-Elvis Worou, Karim Belmokhtar, Pierre Bonnet, Patrick Vourc'h, Marie-Christine Machet, Georges Khamis, Véronique Ede. Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling. Cardiovascular research. vol 91. issue 2. 2011-10-28. PMID:21406596. |
angiotensin ii induces cardiac myocyte apoptosis and hypertrophy, which contribute to heart failure, possibly through enhanced oxidative stress. |
2011-10-28 |
2023-08-12 |
rat |
| Arunachal Chatterjee, Saiful A Mir, Dipanjan Dutta, Arkadeep Mitra, Kanchan Pathak, Sagartirtha Sarka. Analysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy. Journal of cellular physiology. vol 226. issue 10. 2011-10-13. PMID:21792911. |
the triggering mechanisms for cardiac hypertrophy are not clear but both apoptosis and cell proliferation have been reported in sections of failing hearts. |
2011-10-13 |
2023-08-12 |
rat |
| Zohreh Khavandgar, Christophe Poirier, Christopher J Clarke, Jingjing Li, Nicholas Wang, Marc D McKee, Yusuf A Hannun, Monzur Murshe. A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization. The Journal of cell biology. vol 194. issue 2. 2011-10-03. PMID:21788370. |
we examined endochondral ossification in embryonic day 15.5 fro/fro mouse embryos and observed impaired apoptosis of hypertrophic chondrocytes and severely undermineralized cortical bones in the developing skeleton. |
2011-10-03 |
2023-08-12 |
mouse |
| Qingshi Zhao, Amanda J Beck, Joseph M Vitale, Joel S Schneider, Corey Chang, Shumin Gao, Dominic del Re, Mantu Bhaumik, Ghassan Yehia, Junichi Sadoshima, Diego Fraidenraic. Injection of wild type embryonic stem cells into Mst1 transgenic blastocysts prevents adult-onset cardiomyopathy. Stem cell reviews and reports. vol 7. issue 2. 2011-09-30. PMID:21086068. |
as a result, mst1 tg mice develop adult dilated cardiomyopathy driven by apoptosis, reduction in cell density and no hypertrophic compensation. |
2011-09-30 |
2023-08-12 |
mouse |
| Zhicheng Sun, Shirong Li, Chuan Cao, Jun Wu, Bing Ma, Vu Tra. shRNA targeting SFRP2 promotes the apoptosis of hypertrophic scar fibroblast. Molecular and cellular biochemistry. vol 352. issue 1-2. 2011-09-30. PMID:21287236. |
shrna targeting sfrp2 promotes the apoptosis of hypertrophic scar fibroblast. |
2011-09-30 |
2023-08-12 |
Not clear |
| Zhicheng Sun, Shirong Li, Chuan Cao, Jun Wu, Bing Ma, Vu Tra. shRNA targeting SFRP2 promotes the apoptosis of hypertrophic scar fibroblast. Molecular and cellular biochemistry. vol 352. issue 1-2. 2011-09-30. PMID:21287236. |
although the basic mechanism is unclear, increased proliferation and decreased cell apoptosis are noticed in the development of hypertrophic scar. |
2011-09-30 |
2023-08-12 |
Not clear |
| Zhicheng Sun, Shirong Li, Chuan Cao, Jun Wu, Bing Ma, Vu Tra. shRNA targeting SFRP2 promotes the apoptosis of hypertrophic scar fibroblast. Molecular and cellular biochemistry. vol 352. issue 1-2. 2011-09-30. PMID:21287236. |
in previous study, we found that secreted frizzled-related protein 2 (sfrp2), which was associated with cell proliferation, apoptosis, and differentiation, was dramatically upregulated in hypertrophic scar (hs) tissue. |
2011-09-30 |
2023-08-12 |
Not clear |
| Andrew J Boyle, Henry Shih, Joy Hwang, Jianqin Ye, Brian Lee, Yan Zhang, David Kwon, Kristine Jun, Daiwei Zheng, Rich Sievers, Franca Angeli, Yerem Yeghiazarians, Randall Le. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Experimental gerontology. vol 46. issue 7. 2011-09-28. PMID:21377520. |
cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. |
2011-09-28 |
2023-08-12 |
mouse |
| Raj Kamal Srivastava, Amitabh Krishn. Increased circulating leptin level inhibits folliculogenesis in vespertilionid bat, Scotophilus heathii. Molecular and cellular endocrinology. vol 337. issue 1-2. 2011-09-26. PMID:21277349. |
adiposity associated increase in circulating leptin level down regulate ovarian lh-receptor expression and produce characteristic morphological changes in the antral follicles, such as hypertrophy of granulosa cells and a sharp decline in the rate of proliferation as well as apoptosis in the antral follicles. |
2011-09-26 |
2023-08-12 |
Not clear |
| Elza D van Deel, Martine de Boer, Diederik W Kuster, Nicky M Boontje, Patricia Holemans, Karin R Sipido, Jolanda van der Velden, Dirk J Duncke. Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis. Journal of molecular and cellular cardiology. vol 50. issue 6. 2011-09-26. PMID:21291889. |
mtac produced ~40% lv hypertrophy and increased myocardial expression of hypertrophy marker genes but did not affect lv function, serca2a protein levels, apoptosis or capillary density. |
2011-09-26 |
2023-08-12 |
mouse |
| Elza D van Deel, Martine de Boer, Diederik W Kuster, Nicky M Boontje, Patricia Holemans, Karin R Sipido, Jolanda van der Velden, Dirk J Duncke. Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis. Journal of molecular and cellular cardiology. vol 50. issue 6. 2011-09-26. PMID:21291889. |
stac produced ~80% lv hypertrophy and further increased anp expression and interstitial fibrosis and, in contrast with mtac, also produced lv dilation, systolic as well as diastolic dysfunction, pulmonary congestion, apoptosis and capillary rarefaction and decreased serca2a and ryanodine receptor (ryr) protein levels. |
2011-09-26 |
2023-08-12 |
mouse |
| Xiao H Xu, Jing Xu, Lei Xue, Hai L Cao, Xiang Liu, Yi J Che. VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation. Journal of cardiothoracic surgery. vol 6. 2011-09-26. PMID:21496294. |
vegf attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation. |
2011-09-26 |
2023-08-12 |
Not clear |
| Lin Sun, Xiuli Wang, David L Kapla. A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis. Biomaterials. vol 32. issue 24. 2011-09-23. PMID:21565399. |
chondrocyte hypertrophy and apoptosis were assessed via collagen type x and caspase-3. |
2011-09-23 |
2023-08-12 |
human |
| Lin Sun, Xiuli Wang, David L Kapla. A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis. Biomaterials. vol 32. issue 24. 2011-09-23. PMID:21565399. |
in addition, mcm stimulation led to hypertrophy and apoptosis of chondrocytes, outcomes not found with the cytokine treatment group. |
2011-09-23 |
2023-08-12 |
human |
| Hitoshi Ishimoto, Robert B Jaff. Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit. Endocrine reviews. vol 32. issue 3. 2011-09-16. PMID:21051591. |
the gland rapidly grows through processes including cell proliferation and angiogenesis at the gland periphery, cellular migration, hypertrophy, and apoptosis. |
2011-09-16 |
2023-08-12 |
human |