| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongyi Wang, Bingyu Guo, Shixiu Lin, Peng Chang, Kai Ta. Apigenin inhibits growth and migration of fibroblasts by suppressing FAK signaling. Aging. vol 11. issue 11. 2020-07-13. PMID:31170089. |
after isolating fibroblasts from human hypertrophic scars, we assess the effects of apigenin on fibroblast cell survival, apoptosis and migration. |
2020-07-13 |
2023-08-13 |
human |
| Dan Hu, Yu-Xia Cui, Man-Yan Wu, Long Li, Li-Na Su, Zheng Lian, Hong Che. Cytosolic DNA sensor cGAS plays an essential pathogenetic role in pressure overload-induced heart failure. American journal of physiology. Heart and circulatory physiology. vol 318. issue 6. 2020-07-13. PMID:32383996. |
whereas tac mice exhibited significant pathological cardiac remodeling and lv dysfunction, inhibition of cgas improved early survival rates after tac, preserved lv contractile function, and blunted pathological remodeling, including cardiac hypertrophy, fibrosis, and apoptosis. |
2020-07-13 |
2023-08-13 |
mouse |
| Lu Xia, Meiyi Son. Role of Non-coding RNA in Diabetic Cardiomyopathy. Advances in experimental medicine and biology. vol 1229. 2020-07-01. PMID:32285412. |
diabetic cardiomyopathy (dcm) is the leading cause of morbidity and mortality in diabetic population worldwide, characteristic by cardiomyocyte hypertrophy, apoptosis and myocardial interstitial fibrosis and eventually developing into heart failure. |
2020-07-01 |
2023-08-13 |
human |
| Ming-Yue Xu, Zhi-Shuai Ye, Xian-Tao Song, Rong-Chong Huan. Differences in the cargos and functions of exosomes derived from six cardiac cell types: a systematic review. Stem cell research & therapy. vol 10. issue 1. 2020-06-29. PMID:31248454. |
exosomes from different cardiac cells participate in the processes of cell migration, proliferation, apoptosis, hypertrophy, and regeneration, as well as angiogenesis and enhanced cardiac function, which accelerate cardiac repair. |
2020-06-29 |
2023-08-13 |
Not clear |
| Neetu Singh, Mohammad Shafiq, Kumaravelu Jagavelu, Kashif Hani. Involvement of fatty acid synthase in right ventricle dysfunction in pulmonary hypertension. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31465767. |
sirna mediated inhibition of fas reduced fas expression, hypertrophy, inflammation, apoptosis, autophagy and improved the glucose oxidation, mitochondrial membrane potential and atp level in hypoxic cardiomyocytes. |
2020-06-29 |
2023-08-13 |
rat |
| Vrinda Saraff, Ruchi Nadar, Wolfgang Högle. New Developments in the Treatment of X-Linked Hypophosphataemia: Implications for Clinical Management. Paediatric drugs. vol 22. issue 2. 2020-06-26. PMID:31965544. |
prolonged hypophosphataemia decreases apoptosis of hypertrophic chondrocytes in growth plates (causing rickets) and decreases mineralisation of existing bone (causing osteomalacia). |
2020-06-26 |
2023-08-13 |
Not clear |
| Xiaoli Hua, Yi Wang, Chunbo Yang, Ruifeng Chai, Xiang Li, Gulifeire Tayier, Pengfei Pan, Xiangyou Y. Effect of incubation with lipopolysaccharide and interferon-γ on reactive astrogliosis. Journal of integrative neuroscience. vol 18. issue 4. 2020-06-22. PMID:31912700. |
the levels of tumor necrosis factor-α, interleukin-6, nitric oxide, reactive oxygen species, and glial fibrillary acidic protein were increased, hypertrophy of astrocytes was observed, and apoptosis was increased. |
2020-06-22 |
2023-08-13 |
rat |
| Firdos Ahmad, Anand P Singh, Dhanendra Tomar, Mohamed Rahmani, Qinkun Zhang, James R Woodgett, Douglas G Tilley, Hind Lal, Thomas Forc. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. Journal of molecular and cellular cardiology. vol 130. 2020-06-17. PMID:30928428. |
consistent with attenuated hypertrophy, significantly lower level of cardiomyocyte apoptosis was observed in the cko. |
2020-06-17 |
2023-08-13 |
mouse |
| Milan Obradovic, Sonja Zafirovic, Sanja Soskic, Julijana Stanimirovic, Andreja Trpkovic, Danimir Jevremovic, Esma R Isenovi. Effects of IGF-1 on the Cardiovascular System. Current pharmaceutical design. vol 25. issue 35. 2020-06-16. PMID:31692426. |
despite systemic effects, igf-1 exerts a wide array of influences in the cv system affecting metabolic homeostasis, vasorelaxation, cardiac contractility and hypertrophy, autophagy, apoptosis, and antioxidative processes. |
2020-06-16 |
2023-08-13 |
human |
| Bingyu Guo, Qiang Hui, Zhishan Xu, Peng Chang, Kai Ta. miR-495 inhibits the growth of fibroblasts in hypertrophic scars. Aging. vol 11. issue 9. 2020-06-12. PMID:31085805. |
we also used 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide and annexin v-fluorescein isothiocyanate/propidium iodide assays to assess the effect of mir-495 on the proliferation and apoptosis in human hypertrophic scar fibroblasts. |
2020-06-12 |
2023-08-13 |
human |
| E Agbo, M-X Li, Y-Q Wang, R-O Saahene, J Massaro, G-Z Tia. Hexarelin protects cardiac H9C2 cells from angiotensin II-induced hypertrophy Die Pharmazie. vol 74. issue 8. 2020-06-11. PMID:31526442. |
ang-ii induced cardiomyocyte hypertrophy, oxidative stress, apoptosis and decreased cell survival, all of which were significantly suppressed by hexarelin treatment which also enhanced autophagy in hypertrophic h9c2 cells. |
2020-06-11 |
2023-08-13 |
Not clear |
| E Agbo, M-X Li, Y-Q Wang, R-O Saahene, J Massaro, G-Z Tia. Hexarelin protects cardiac H9C2 cells from angiotensin II-induced hypertrophy Die Pharmazie. vol 74. issue 8. 2020-06-11. PMID:31526442. |
conversely, the application of autophagy stimulator rapamycin in h9c2 hypertrophic cells inhibited apoptosis, cell survival and reduced cell size as well. |
2020-06-11 |
2023-08-13 |
Not clear |
| E Agbo, M-X Li, Y-Q Wang, R-O Saahene, J Massaro, G-Z Tia. Hexarelin protects cardiac H9C2 cells from angiotensin II-induced hypertrophy Die Pharmazie. vol 74. issue 8. 2020-06-11. PMID:31526442. |
we propose that hexarelin plays a novel role of attenuating cardiomyocyte hypertrophy and apoptosis |
2020-06-11 |
2023-08-13 |
Not clear |
| Ruli Li, Xiaoxiao Wang, Sisi Wu, Yao Wu, Hongying Chen, Juanjuan Xin, He Li, Jie Lan, Kunyue Xue, Xue Li, Caili Zhuo, Jinhan He, Chao-Shu Tang, Wei Jian. Irisin ameliorates angiotensin II-induced cardiomyocyte apoptosis through autophagy. Journal of cellular physiology. vol 234. issue 10. 2020-06-08. PMID:30793300. |
in animal experiments, overexpression of irisin reduced cardiomyocyte apoptosis and alleviated myocardial hypertrophy caused by pressure overload. |
2020-06-08 |
2023-08-13 |
Not clear |
| Chun-Nun Chao, Chao-Hung Lai, Khan Farheen Badrealam, Jeng-Fan Lo, Chia-Yao Shen, Chia-Hua Chen, Ray-Jade Chen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huan. CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation. Journal of cellular physiology. vol 234. issue 11. 2020-05-29. PMID:30980393. |
chip attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting nfatc3 proteasomal degradation. |
2020-05-29 |
2023-08-13 |
Not clear |
| Chun-Nun Chao, Chao-Hung Lai, Khan Farheen Badrealam, Jeng-Fan Lo, Chia-Yao Shen, Chia-Hua Chen, Ray-Jade Chen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huan. CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation. Journal of cellular physiology. vol 234. issue 11. 2020-05-29. PMID:30980393. |
moreover, actin staining and tunel assay further ascertained the attenuation of cardiac hypertrophy and apoptosis following overexpression of chip respectively. |
2020-05-29 |
2023-08-13 |
Not clear |
| Chun-Nun Chao, Chao-Hung Lai, Khan Farheen Badrealam, Jeng-Fan Lo, Chia-Yao Shen, Chia-Hua Chen, Ray-Jade Chen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huan. CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation. Journal of cellular physiology. vol 234. issue 11. 2020-05-29. PMID:30980393. |
taken together, our study reveals that chip attenuates lps-induced cardiac hypertrophy and apoptosis perhaps by promoting nfatc3 proteasomal degradation. |
2020-05-29 |
2023-08-13 |
Not clear |
| Rui He, Chang Ding, Ping Yin, Li He, Qing Xu, Zhenru Wu, Yujun Shi, Li S. MiR-1a-3p mitigates isoproterenol-induced heart failure by enhancing the expression of mitochondrial ND1 and COX1. Experimental cell research. vol 378. issue 1. 2020-05-26. PMID:30853447. |
cardiac hypertrophy, myocardial fibrosis, apoptosis, and glycogen deposition were reduced in mice treated with agomir-1. |
2020-05-26 |
2023-08-13 |
mouse |
| Chieh-Hsiang Lu, Hsiu-Chung Ou, Cecilia-Hsuan Day, Hsiu-I Chen, Pei-Ying Pai, Cheng-Yu Lee, Ray-Jade Chen, Ruey-Lin Chang, Vijaya PadmaViswanadha, Dennis Jine-Yuan Hsieh, Chih-Yang Huan. Deep sea minerals ameliorate diabetic-induced inflammation via inhibition of TNFα signaling pathways. Environmental toxicology. vol 35. issue 4. 2020-05-26. PMID:31794124. |
it has been well-documented that the consumption of deep sea water (dsw) has beneficial effects on myocardial hypertrophy and cardiac apoptosis induced by hypercholesterolemia. |
2020-05-26 |
2023-08-13 |
rat |
| Zhi-Qing Chen, Feng Chen, Lang L. LncRNA GAS5 aggravates pathological cardiac hypertrophy by targeting miR-135b to mediate apoptosis. International journal of cardiology. vol 294. 2020-05-25. PMID:31296392. |
lncrna gas5 aggravates pathological cardiac hypertrophy by targeting mir-135b to mediate apoptosis. |
2020-05-25 |
2023-08-13 |
Not clear |