| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Jiang, Xiaoyan Wang, Xiaopeng Zhan, Sheng Kang, Haibo Liu, Yu Luo, Li Li. Advance in circular RNA modulation effects of heart failure. Gene: X. vol 5. 2020-09-28. PMID:32793879. |
recently, circrnas have been demonstrated to play crucial roles in cardiomyocyte hypertrophy, fibrosis, autophagy and apoptosis, participating in the development of heart failure. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yun-Jie Wei, Hai-Jun Xu, Jia-Juan Chen, Xi Yang, Jian Xiong, Jing Wang, Fei Chen. Carnosic acid protects against pressure overload-induced cardiac remodelling by inhibiting the AKT/GSK3β/NOX4 signalling pathway. Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32855722. |
ca treatment decreased cardiac hypertrophy, fibrosis, oxidative stress and apoptosis in mice challenged with pressure overload. |
2020-09-28 |
2023-08-13 |
mouse |
| Efta Triastuti, Ardiansah Bayu Nugroho, Min Zi, Sukhpal Prehar, Yulia Suciati Kohar, Thuy Anh Bui, Nicholas Stafford, Elizabeth J Cartwright, Sabu Abraham, Delvac Oceand. Pharmacological inhibition of Hippo pathway, with the novel kinase inhibitor XMU-MP-1, protects the heart against adverse effects during pressure overload. British journal of pharmacology. vol 176. issue 20. 2020-09-22. PMID:31328787. |
the core components of the hippo pathway, mammalian ste-20 like kinase 1 (mst1) and mammalian ste-20 like kinase 2 (mst2), modulate cardiac hypertrophy, apoptosis, and fibrosis. |
2020-09-22 |
2023-08-13 |
Not clear |
| Zhaofu Liao, Dan Li, Yilin Chen, Yunjian Li, Ruijin Huang, Kuikui Zhu, Hongyi Chen, Ziqiang Yuan, Xin Zheng, Hui Zhao, Qin Pu, Xufeng Qi, Dongqing Ca. Early moderate exercise benefits myocardial infarction healing via improvement of inflammation and ventricular remodelling in rats. Journal of cellular and molecular medicine. vol 23. issue 12. 2020-09-22. PMID:31612566. |
in the present study, we demonstrated that acute mi rats that underwent early moderate exercise training beginning one day after mi showed no increase in mortality and displayed significant improvements in mi healing and ventricular remodelling, including an improvement in cardiac function, a decrease in infarct size, cardiomyocyte apoptosis, cardiac fibrosis and cardiomyocyte hypertrophy, and an increase in myocardial angiogenesis, left ventricular wall thickness and the number of cardiac telocytes in the border zone. |
2020-09-22 |
2023-08-13 |
rat |
| Sudhir Pandey, Wei-Wen Kuo, Tsung-Jung Ho, Yu-Lan Yeh, Chia-Yao Shen, Ray-Jade Chen, Ruey-Lin Chang, Pei-Ying Pai, V Vijaya Padma, Chih-Yang Huang, Chih-Yang Huan. Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31104312. |
overexpression of igf-iirα leads to cumulative elevation of stress associated cardiac hypertrophy and apoptosis factors. |
2020-09-14 |
2023-08-13 |
rat |
| Xiaonan Zhang, Shaoyang Dong, Qiujin Jia, Ao Zhang, Yanyang Li, Yaping Zhu, Shichao Lv, Junping Zhan. The microRNA in ventricular remodeling: the miR-30 family. Bioscience reports. vol 39. issue 8. 2020-09-14. PMID:31320543. |
ventricular remodeling (vr) is a complex pathological process of cardiomyocyte apoptosis, cardiac hypertrophy, and myocardial fibrosis, which is often caused by various cardiovascular diseases (cvds) such as hypertension, acute myocardial infarction, heart failure (hf), etc. |
2020-09-14 |
2023-08-13 |
Not clear |
| Bin Wu, Xue-Yuan Huang, Le Li, Xiao-Hang Fan, Peng-Cheng Li, Chuan-Qi Huang, Juan Xiao, Rong Gui, Shun Wan. Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model. Journal of cellular and molecular medicine. vol 23. issue 11. 2020-09-09. PMID:31565849. |
left ventricular dysfunction, hypertrophy, fibrosis and cell apoptosis, as structural and functional abnormalities, were ameliorated by kirenol administration. |
2020-09-09 |
2023-08-13 |
rat |
| Chun-Nun Chao, Jeng-Fan Lo, Farheen B Khan, Cecilia H Day, Chao-Hung Lai, Chia-Hua Chen, Ray-Jade Chen, Vijaya P Viswanadha, Chia-Hua Kuo, Chih-Yang Huan. Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-02. PMID:31081962. |
tid1-s attenuates lps-induced cardiac hypertrophy and apoptosis through er-a mediated modulation of p-pi3k/p-akt signaling cascade. |
2020-09-02 |
2023-08-13 |
Not clear |
| Chun-Nun Chao, Jeng-Fan Lo, Farheen B Khan, Cecilia H Day, Chao-Hung Lai, Chia-Hua Chen, Ray-Jade Chen, Vijaya P Viswanadha, Chia-Hua Kuo, Chih-Yang Huan. Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-02. PMID:31081962. |
however, the role of tid 1 in lipopolysaccharide (lps)-induced cardiomyocyte hypertrophy and apoptosis remains elusive. |
2020-09-02 |
2023-08-13 |
Not clear |
| Chun-Nun Chao, Jeng-Fan Lo, Farheen B Khan, Cecilia H Day, Chao-Hung Lai, Chia-Hua Chen, Ray-Jade Chen, Vijaya P Viswanadha, Chia-Hua Kuo, Chih-Yang Huan. Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-02. PMID:31081962. |
in the current research endeavor, we have elucidated the role of tid1-s on lps-induced cardiac hypertrophy and apoptosis. |
2020-09-02 |
2023-08-13 |
Not clear |
| Yi Xiao, Jiling Zhao, Julian P Tuazon, Cesar V Borlongan, Guolong Y. MicroRNA-133a and Myocardial Infarction. Cell transplantation. vol 28. issue 7. 2020-08-31. PMID:30983393. |
in this review, we summarize recent research progress highlighting the regulatory effects of mir-133a in ischemic myocardial diseases, such as inhibiting angiogenesis, apoptosis, fibrosis, hypertrophy, and inflammation, while promoting therapeutic cardiac remodeling. |
2020-08-31 |
2023-08-13 |
Not clear |
| Chyi-Huey Bai, Javad Alizargar, Ching-Yi Peng, Jia-Ping W. Combination of exercise training and resveratrol attenuates obese sarcopenia in skeletal muscle atrophy. The Chinese journal of physiology. vol 63. issue 3. 2020-08-31. PMID:32594063. |
mitochondrial function expression, apoptosis and relative hypertrophy signaling in hfd-induced obesity mice and samp8 mice were determined by western blot analysis. |
2020-08-31 |
2023-08-13 |
mouse |
| L X Tu, D W Li. [Research advances in the role of ubiquitin-proteasome pathway in hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 36. issue 8. 2020-08-26. PMID:32829623. |
recent studies have found that the ubiquitin-proteasome pathway can participate in the formation and development of hypertrophic scar by regulating transforming growth factor beta/smad signal transduction and proliferation, differentiation, and apoptosis of fibroblasts. |
2020-08-26 |
2023-08-13 |
Not clear |
| Navid Omidkhoda, A Wallace Hayes, Russel J Reiter, Gholamreza Karim. The role of MicroRNAs on endoplasmic reticulum stress in myocardial ischemia and cardiac hypertrophy. Pharmacological research. vol 150. 2020-08-24. PMID:31698066. |
the mirnas play important roles in regulating cardiac physiological and pathological events such as hypertrophy, apoptosis, and heart failure. |
2020-08-24 |
2023-08-13 |
Not clear |
| Koji Mizuhashi, Mizuki Nagata, Yuki Matsushita, Wanida Ono, Noriaki On. Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 34. issue 8. 2020-08-13. PMID:30888720. |
the current model postulates that a group of chondrocytes in the hypertrophic zone can escape from apoptosis and transform into cells that eventually become osteoblasts in an area beneath the growth plate. |
2020-08-13 |
2023-08-13 |
mouse |
| Julian C Lui, Shanna Yue, Audrey Lee, Bijal Kikani, Adrian Temnycky, Kevin M Barnes, Jeffrey Baro. Persistent Sox9 expression in hypertrophic chondrocytes suppresses transdifferentiation into osteoblasts. Bone. vol 125. 2020-08-03. PMID:31121357. |
in the postnatal growth plate, as hypertrophic chondrocytes approach the chondro-osseous junction, they may undergo apoptosis, or directly transdifferentiate into osteoblasts. |
2020-08-03 |
2023-08-13 |
mouse |
| Miles A Tanner, Toby P Thomas, Laurel A Grisant. Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivation. Journal of molecular and cellular cardiology. vol 136. 2020-08-03. PMID:31473246. |
taken together, these studies identify a previously unidentified role for dr5 in the heart, which does not promote apoptosis but acts through non-canonical mmp-egfr-erk1/2 signaling mechanisms to contribute to cardiomyocyte hypertrophy. |
2020-08-03 |
2023-08-13 |
mouse |
| Jakub Gumprecht, Magdalena Domek, Gregory Y H Lip, Alena Shantsil. Invited review: hypertension and atrial fibrillation: epidemiology, pathophysiology, and implications for management. Journal of human hypertension. vol 33. issue 12. 2020-08-03. PMID:31690818. |
it also stimulates cardiomyocytes apoptosis and inflammation, leading to diffused fibrosis and left ventricular hypertrophy development. |
2020-08-03 |
2023-08-13 |
Not clear |
| Zhongwen Qi, Dan Wu, Meng Li, Zhipeng Yan, Xiaoya Yang, Nan Ji, Yueyao Wang, Junping Zhan. The pluripotent role of exosomes in mediating non-coding RNA in ventricular remodeling after myocardial infarction. Life sciences. vol 254. 2020-07-23. PMID:32413403. |
in recent years, the molecular mechanism of vr has been studied mainly from the aspects of myocardial hypertrophy, myocardial fibrosis, inflammation, myocardial energy disorder, apoptosis, autophagy and pyroptosis. |
2020-07-23 |
2023-08-13 |
Not clear |
| Qiang Zhao, Tao Yan, Linlin Li, Michael Chopp, Poornima Venkat, Yu Qian, Ran Li, Ruixia Wu, Wei Li, Mei Lu, Talan Zhang, Jieli Che. Immune Response Mediates Cardiac Dysfunction after Traumatic Brain Injury. Journal of neurotrauma. vol 36. issue 4. 2020-07-21. PMID:30045672. |
in addition, these mice exhibited significantly increased cardiomyocyte apoptosis, inflammation, and oxidative stress at 3 and 30 days post-tbi, as well as cardiac hypertrophy and fibrosis and ventricular dilatation at 30 days after tbi. |
2020-07-21 |
2023-08-13 |
mouse |