| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ju-Dong Lee, Haiyoung Jung, Sang-Hyun Mi. Identification of proteins suppressing the functions of oncogenic phosphatase of regenerating liver 1 and 3. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882103. |
these proteins are associated with cell proliferation, apoptosis, immune response, cell fate specification and metabolic process in biological process categories, and involved in various signaling pathways, including alzheimer's disease, parkinson's disease, huntington's disease, hypertrophic cardiomyopathy and cell adhesion molecules. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xi. Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29922164. |
we have previously reported that shikonin induces apoptosis and reduces collagen production in hypertrophic scar fibroblasts |
2020-09-30 |
2023-08-13 |
human |
| Gang Li, Han Zhang, Lei Zhao, Yaozhong Zhang, Daole Yan, Yinglong Liu, Junwu Su, Xiangming Fa. The expression of survivin in irreversible pulmonary arterial hypertension rats and its value in evaluating the reversibility of pulmonary arterial hypertension secondary to congenital heart disease. Pulmonary circulation. vol 9. issue 3. 2020-09-30. PMID:31428312. |
irreversible pah rats were characterized by prominent obstructive lesions resulting from the intimal formation, which was associated with decreased apoptosis and increased survivin expression, while reversible pah rats were featured by medial hypertrophy resulting in mild occlusion, with increased apoptosis and unchanged survivin expression. |
2020-09-30 |
2023-08-13 |
rat |
| Yiping Li, Xiaofen Ruan, Xiaowen Xu, Cha Li, Tingting Qiang, Hua Zhou, Junjie Gao, Xiaolong Wan. Shengmai Injection Suppresses Angiotensin II-Induced Cardiomyocyte Hypertrophy and Apoptosis Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31616303. |
shengmai injection suppresses angiotensin ii-induced cardiomyocyte hypertrophy and apoptosis shengmai injection (smi), a traditional chinese herbal medicine extracted from panax ginseng c.a. |
2020-09-30 |
2023-08-13 |
Not clear |
| Eduardo T Santana, Regiane Dos Santos Feliciano, Andrey J Serra, Eduardo Brigidio, Ednei L Antonio, Paulo J F Tucci, Lubov Nathanson, Mariana Morris, José A Silv. Comparative mRNA and MicroRNA Profiling during Acute Myocardial Infarction Induced by Coronary Occlusion and Ablation Radio-Frequency Currents. Frontiers in physiology. vol 7. 2020-09-29. PMID:27932994. |
we analyzed 48 mrnas expressions of nine different signal transduction pathways (cell survival and metabolism signs, matrix extracellular, cell cycle, oxidative stress, apoptosis, calcium signaling, hypertrophy markers, angiogenesis, and inflammation) in rat left ventricle 1 week after mi generated by both coronary occlusion and ab-rf. |
2020-09-29 |
2023-08-13 |
rat |
| Alicja Bukowska, Uwe Lendeckel, Andreas Goett. Atrial Calpains: Mediators of Atrialmyopathies in Atrial Fibrillation. Journal of atrial fibrillation. vol 6. issue 6. 2020-09-29. PMID:27957058. |
cellular hypertrophy, disintegration of sarcomeres, mitochondrial swelling and apoptosis have been described as typical histo-morphologic alterations in af. |
2020-09-29 |
2023-08-13 |
Not clear |
| Guangwang Liu, Chao Ma, Huilin Yang, Pei-Ying Zhan. Transforming growth factor β and its role in heart disease. Experimental and therapeutic medicine. vol 13. issue 5. 2020-09-29. PMID:28565818. |
tgfβ appears to be a 'master of all trades', with respect to cardiac fibrosis, as it can promote cardiomyocyte apoptosis and cardiac hypertrophy. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xiao Wei, Yuan Yang, Yin-Jiu Jiang, Jian-Ming Lei, Jing-Wen Guo, Hua Xia. Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399073. |
relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the notch1 pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xiao Wei, Yuan Yang, Yin-Jiu Jiang, Jian-Ming Lei, Jing-Wen Guo, Hua Xia. Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399073. |
the present study aimed to investigate the role of relaxin (rlx) on high glucose (hg)-induced cardiomyocyte hypertrophy and apoptosis, as well as the possible molecular mechanism. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xiao Wei, Yuan Yang, Yin-Jiu Jiang, Jian-Ming Lei, Jing-Wen Guo, Hua Xia. Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399073. |
cell viability, apoptosis, oxidative stress, cell hypertrophy and the levels of notch1, hairy and enhancer of split 1 (hes1), atrial natriuretic polypeptide (anp), brain natriuretic peptide (bnp), manganese superoxide dismutase (mnsod), cytochrome c and caspase-3 were assessed in cardiomyocytes. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xiao Wei, Yuan Yang, Yin-Jiu Jiang, Jian-Ming Lei, Jing-Wen Guo, Hua Xia. Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399073. |
these results suggested that rlx protected cardiomyocytes from hg-induced hypertrophy and apoptosis partly through a notch1-dependent pathway, which may be associated with reducing oxidative stress. |
2020-09-29 |
2023-08-13 |
Not clear |
| Patrick Aghajanian, Subburaman Moha. The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification. Bone research. vol 6. 2020-09-29. PMID:29928541. |
the canonical pathway of the endochondral bone formation process involves apoptosis of hypertrophic chondrocytes followed by vascular invasion that brings in osteoclast precursors to remove cartilage and osteoblast precursors to form bone. |
2020-09-29 |
2023-08-13 |
Not clear |
| Sung Sup Park, Eun-Soo Kwon, Ki-Sun Kwo. Molecular mechanisms and therapeutic interventions in sarcopenia. Osteoporosis and sarcopenia. vol 3. issue 3. 2020-09-29. PMID:30775515. |
to develop a new therapeutic intervention needed is the detailed understanding of molecular and cellular mechanisms by which apoptosis, autophagy, atrophy, and hypertrophy occur in the muscle stem cells, myotubes, and/or neuromuscular junction. |
2020-09-29 |
2023-08-13 |
Not clear |
| Bo Liu, Zhe Guo, Weiming Ga. miR-181b-5p promotes proliferation and inhibits apoptosis of hypertrophic scar fibroblasts through regulating the MEK/ERK/p21 pathway. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783419. |
mir-181b-5p promotes proliferation and inhibits apoptosis of hypertrophic scar fibroblasts through regulating the mek/erk/p21 pathway. |
2020-09-29 |
2023-08-13 |
human |
| Nasiruddin Nalban, Rajendra Sangaraju, Sateesh Alavala, Salma Mukhtar Mir, Mahesh Kumar Jerald, Ramakrishna Sistl. Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. Cardiovascular toxicology. vol 20. issue 3. 2020-09-28. PMID:31485892. |
iso-alone-treated group showed significant increase in ck-mb, ldh along with increase in hypertrophic markers anp and bnp, tnf-α and il-6 levels in serum and tissues and increased cardiomyocyte apoptosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Yi Wang, Zhiheng Guo, Yongmei Gao, Ping Liang, Yanhong Shan, Jin H. Angiotensin II receptor blocker LCZ696 attenuates cardiac remodeling through the inhibition of the ERK signaling pathway in mice with pregnancy-associated cardiomyopathy. Cell & bioscience. vol 9. 2020-09-28. PMID:31649814. |
lcz696 attenuated cardiac injury induced by ang ii through the inhibition the expression of markers of cardiac hypertrophy, fibrosis and apoptosis by inhibiting erk phosphorylation in vivo and in vitro. |
2020-09-28 |
2023-08-13 |
mouse |
| Negar Etehad Roodi, Nushin Karkuki Osguei, Mahdy Hasanzadeh Daloee, Alireza Pasdar, Majid Ghayour-Mobarhan, Gordon Ferns, Ali Samadi Kuchaksarae. Association of Endonuclease G Gene Variants with Cardiovascular Disease Risk Factors. Reports of biochemistry & molecular biology. vol 8. issue 2. 2020-09-28. PMID:31832438. |
endonuclease g (endog) has recently been suggested to be a novel determinant of cardiac hypertrophy and mitochondrial function, and plays an important role in apoptosis processes involved in cardiac myocyte death. |
2020-09-28 |
2023-08-13 |
Not clear |
| Nina Kaludercic, Fabio Di Lis. Mitochondrial ROS Formation in the Pathogenesis of Diabetic Cardiomyopathy. Frontiers in cardiovascular medicine. vol 7. 2020-09-28. PMID:32133373. |
indeed, key processes underlying cardiac remodeling in diabetes are redox sensitive, including inflammation, organelle dysfunction, alteration in ion homeostasis, cardiomyocyte hypertrophy, apoptosis, fibrosis, and contractile dysfunction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xue Wu, Zheng Wang, Gaofeng Wu, Xiaofan Xu, Jian Zhang, Yan Li, Hong Zhang, Shuzhen Gu. Tetramethylpyrazine Induces Apoptosis and Inhibits Proliferation of Hypertrophic Scar-Derived Fibroblasts Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32431617. |
tetramethylpyrazine induces apoptosis and inhibits proliferation of hypertrophic scar-derived fibroblasts hypertrophic scar (hs) is a serious fibrotic skin disease and often considered as a kind of benign skin tumor. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ji Eun Park, Heaji Lee, Hyunkyung Rho, Seong Min Hong, Sun Yeou Kim, Yunsook Li. Effect of Antioxidants (Basel, Switzerland). vol 9. issue 6. 2020-09-28. PMID:32471242. |
especially, hyperglycemia causes hyper-inflammation through activation of nlrp3 inflammasome, which can lead to cell apoptosis, hypertrophy, and fibrosis. |
2020-09-28 |
2023-08-13 |
Not clear |