| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang He, Hecun Zou, Qiang Lyu, Yujing Tang, Wenkui Xiong, Fei-Fei Shan. LncRNA-Profile-Based Screening of Extracellular Vesicles Released from Brain Endothelial Cells after Oxygen-Glucose Deprivation. Brain sciences. vol 12. issue 8. 2022-08-26. PMID:36009090. |
the results showed that the lncrnas may play roles in apoptosis, the tnf signaling pathway, and leukocyte transendothelial migration. |
2022-08-26 |
2023-08-14 |
human |
| Chuen-Mao Yang, Chien-Chung Yang, Wun-Hsin Hsu, Li-Der Hsiao, Hui-Ching Tseng, Ya-Fang Shi. Tumor Necrosis Factor-α-Induced C-C Motif Chemokine Ligand 20 Expression through TNF Receptor 1-Dependent Activation of EGFR/p38 MAPK and JNK1/2/FoxO1 or the NF-κB Pathway in Human Cardiac Fibroblasts. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012347. |
tumor necrosis factor (tnf)-α is involved in the pathogenesis of cardiac injury, inflammation, and apoptosis. |
2022-08-26 |
2023-08-14 |
human |
| A A H Abdellatif, S K Osman, M Alsharidah, O Al Rugaie, T M Faris, A Alqasoumi, A M Mousa, A Bouazzaou. Green synthesis of silver nanoparticles reduced with Trigonella foenum-graecum and their effect on tumor necrosis factor-α in MCF7 cells. European review for medical and pharmacological sciences. vol 26. issue 15. 2022-08-22. PMID:35993650. |
they have been reported to reduce the levels of tumor necrosis factor (tnf) - a proinflammatory cytokine involved in cell proliferation, differentiation, and apoptosis - in cell lines. |
2022-08-22 |
2023-08-14 |
human |
| Qian Yang, Qi Sun, Ping Ji. Long non-coding RNA PVT1 regulates LPS-induced acute kidney injury in an Experimental and therapeutic medicine. vol 24. issue 3. 2022-08-18. PMID:35978931. |
furthermore, lps treatment could promote the secretion of tumor necrosis factor (tnf)-α and interleukin (il)-6, inhibit cell proliferation and induce apoptosis, which was rescued by pvt1 knockdown. |
2022-08-18 |
2023-08-14 |
Not clear |
| Jianan Li, Haoran B. Integrated Strategy of Network Pharmacology and in vitro Screening to Identify Mechanism of Diazinon-induced Hippocampal Neurotoxicity. Neurotoxicology. 2022-08-07. PMID:35934178. |
dzn-induced hippocampal neurotoxicity was associated with the altered activity of multiple signaling pathways (including pi3k-akt, tnf, and apoptosis signaling). |
2022-08-07 |
2023-08-14 |
mouse |
| Ying Xing, Yuqian Zhang, Congqin Li, Lu Luo, Yan Hua, Jian Hu, Yulong Ba. Repetitive Transcranial Magnetic Stimulation of the Brain After Ischemic Stroke: Mechanisms from Animal Models. Cellular and molecular neurobiology. 2022-08-02. PMID:35917043. |
rtms can prompt synaptic plasticity by increasing nmdar, ampar and bdnf expression; rtms can inhibit pro-inflammatory cytokines tnf and facilitate the expression of anti-inflammatory cytokines il-10 by shifting astrocytic phenotypes from a1 to a2, and shifting microglial phenotypes from m1 to m2; rtms facilitated the release of angiogenesis-related factors tgfβ and vegf in a2 astrocytes, which can contribute to vasculogenesis and angiogenesis; rtms can suppress apoptosis by increasing bcl-2 expression and inhibiting bax, caspase-3 expression; rtms can also suppress pyroptosis by decreasing caspase-1, il-1β, asc, gsdmd and nlrp1 expression. |
2022-08-02 |
2023-08-14 |
Not clear |
| Kuailing Tan, Hongying Mo, Lilu Guo, Binan Wan. MALAT1 accelerates proliferation and inflammation and suppresses apoptosis of endometrial stromal cells via the microRNA-142-3p/CXCR7 axis. Reproductive biology. vol 22. issue 3. 2022-07-28. PMID:35901619. |
then, esc proliferation was assessed by cck-8 and edu labeling assays, apoptosis by flow cytometry, and levels of inflammatory factors tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6 in esc supernatant by enzyme linked immunosorbent assay. |
2022-07-28 |
2023-08-14 |
Not clear |
| Gulsum Akgun-Cagliyan, Aysegul Cort-Donmez, Emine Kilic-Toprak, Fatih Altinta. Verbascoside potentiates the effect of tyrosine kinase inhibitors on the induction of apoptosis and oxidative stress via the Abl-mediated MAPK signalling pathway in chronic myeloid leukaemia. Experimental and therapeutic medicine. vol 24. issue 2. 2022-07-15. PMID:35837042. |
the present study investigated the effect of verb, in combination with imatinib (im), dasatinib (das), lipopolysaccharide (lps) and tnf, on cell survival, abl expression, apoptosis, oxidative stress and the mapk pathway in chronic myeloid leukaemia (cml) cells. |
2022-07-15 |
2023-08-14 |
Not clear |
| Jiangyue Qin, Hao Wang, Zhuoyao Lyu, Yue Liao, Ni Zeng, Ke Wang, Yongfang Zhou, Zijian Zeng, Zenglin Liao, Yufang Cao, Junyun He, Tao Wang, Fuqiang We. Elevated soluble death receptor 5 can predict poor prognosis in patients with acute respiratory distress syndrome. Expert review of respiratory medicine. 2022-07-13. PMID:35822538. |
: the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and its receptor, death receptor 5 (dr5), participate in pulmonary cell apoptosis. |
2022-07-13 |
2023-08-14 |
Not clear |
| Daniel Frank, Sarah E Garnish, Jarrod J Sandow, Ashley Weir, Lin Liu, Elise Clayer, Lizeth Meza, Maryam Rashidi, Simon A Cobbold, Simon R Scutts, Marcel Doerflinger, Holly Anderton, Kate E Lawlor, Najoua Lalaoui, Andrew J Kueh, Vik Ven Eng, Rebecca L Ambrose, Marco J Herold, Andre L Samson, Rebecca Feltham, James M Murphy, Gregor Ebert, Jaclyn S Pearson, James E Vinc. Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death. iScience. vol 25. issue 7. 2022-07-08. PMID:35800780. |
pathogen recognition and tnf receptors signal via receptor interacting serine/threonine kinase-3 (ripk3) to cause cell death, including mlkl-mediated necroptosis and caspase-8-dependent apoptosis. |
2022-07-08 |
2023-08-14 |
Not clear |
| Hai Duc Nguyen, Min-Sun Ki. The Effects of a Mixture of Cadmium, Lead, and Mercury on Metabolic Syndrome and Its Components, as well as Cognitive Impairment: Genes, MicroRNAs, Transcription Factors, and Sponge Relationships : The Effects of a Mixture of Cadmium, Lead, and Mercury on Metabolic Syndrome and Its Components, as well as Cognitive Impairment: Genes, MicroRNAs, Transcription Factors, and Sponge Relationships. Biological trace element research. 2022-07-07. PMID:35798913. |
the genes casp3, bax, bcl2, il6, tnf, apoe, hmox1, and igf were found to be mutually affected by the heavy metal mixture studied, suggesting the importance of apoptosis, inflammation, lipid, heme, and glucose metabolism in mets and cognitive impairment, as well as the potentiality of targeting these genes in prospective therapeutic intervention for these diseases. |
2022-07-07 |
2023-08-14 |
Not clear |
| Sandra S Arango-Varela, Ivan Luzardo-Ocampo, Maria E Maldonado-Celi. Andean berry (Vaccinium meridionale Swartz) juice, in combination with Aspirin, displayed antiproliferative and pro-apoptotic mechanisms in vitro while exhibiting protective effects against AOM-induced colorectal cancer in vivo. Food research international (Ottawa, Ont.). vol 157. 2022-06-28. PMID:35761556. |
the results indicated that aspirin and abj mixtures exhibit antiproliferative and pro-apoptotic effects in sw480 cells inducing mechanisms linked to extrinsic (tnf and trail-mediated apoptosis) and intrinsic (bax and cytochrome c modulation) pathways. |
2022-06-28 |
2023-08-14 |
mouse |
| Liwei Zhang, Yan Shi, Mingzhu Yan, Guangping Zhan. Modulatory action of withaferin-A on oxidative damage through regulation of inflammatory mediators and apoptosis via PI3K/AKT signaling pathway in high cholesterol-induced atherosclerosis in experimental rats. Journal of biochemical and molecular toxicology. 2022-06-23. PMID:35734936. |
wa reduced apoptosis via augmentation of phosphatidylinositol 3-kinase (pi3k)/protein kinase b (akt) pathway; increased b-cell lymphoma 2 and inhibited bcl-2 associated x-protein proapoptotic proteins; tnf receptor superfamily member 6, bim, caspase-3, and -9; demonstrated significant hypolipidemic and anti-inflammatory properties against hcd induced atherosclerosis in rats through regulation of inflammatory mediators and apoptosis via the pi3k/akt signaling pathway. |
2022-06-23 |
2023-08-14 |
rat |
| Katherine Dinh, Qixuan Wan. A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β. Biophysical journal. 2022-06-17. PMID:35714600. |
using the model, we both explore the mechanisms underlying hf cell fate decisions and make predictions that could potentially guide future experiments: 1) we propose that a threshold-like switch in the tgf-β strength may necessitate the dual roles of tgf-β in either activating apoptosis or cell proliferation, in cooperation with bmp and tumor necrosis factor (tnf) and at different stages of a follicle growth cycle; 2) our model shows concordance with the high-activator-low-inhibitor theory of anagen initiation; 3) we predict that tnf may be more effective in catagen initiation than tgf-β, and they may cooperate in a two-step fashion; 4) finally, predictions of gene knockout and overexpression reveal the roles in hf cell fate regulations of each gene. |
2022-06-17 |
2023-08-14 |
Not clear |
| Katherine Dinh, Qixuan Wan. A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β. Biophysical journal. 2022-06-17. PMID:35714600. |
a discrete spatial model equipped with the pbn illustrates how tgf-β and tnf cooperate in initiating and driving the apoptosis wave during catagen. |
2022-06-17 |
2023-08-14 |
Not clear |
| Mustafa Adem Tatlisu, Adem Atici, Fatma Betul Ozcan, Mehmet Çelik, Eray Kirac, Omer Faruk Baycan, Mustafa Caliska. The Association of TWEAK with Coronary Artery Calcification in Patients with Chronic Kidney Disease. Arquivos brasileiros de cardiologia. 2022-06-15. PMID:35703664. |
the soluble tumor necrosis factor-like weak inducer of apoptosis (stweak) is a member of the tnf superfamily that plays a critical role in proliferation and inflammation in the arterial circulation. |
2022-06-15 |
2023-08-14 |
Not clear |
| Weizheng Liang, Xiushen Li, Yue Yao, Qingxue Meng, Xueliang Wu, Hao Wang, Jun Xu. Puerarin: A Potential Therapeutic for Colon Adenocarcinoma (COAD) Patients Suffering From SARS-CoV-2 Infection. Frontiers in pharmacology. vol 13. 2022-06-09. PMID:35677450. |
the results of bioinformatics analysis revealed that puerarin could be able to treat covid-19/coad comorbidity through apoptosis, antiviral, antioxidant, nf-κb signaling pathway, mapk signaling pathway, il-17 signaling pathway, tnf signaling pathway, and hif-1 signaling pathway etc. |
2022-06-09 |
2023-08-14 |
Not clear |
| Amir Raoofi, Ali Delbari, Davood Nasiry, Rahim Golmohammadi, Sara Sadat Javadinia, Reza Sadrzadeh, Mohammad-Shafi Mojadadi, Auob Rustamzadeh, Amin Mousavi Khaneghah, Vahid Ebrahimi, Mohammad Jafar Rezai. Caffeine modulates apoptosis, oxidative stress, and inflammation damage induced by tramadol in cerebellum of male rats. Journal of chemical neuroanatomy. 2022-06-06. PMID:35660069. |
at the end of study (day 21), after performing rotarod behavioral test, cerebellum tissue samples were removed and prepared for further evaluations including biochemical profile markers (mda, gpx, and sod), immunohistochemistry for caspase-3, as well as the expression of genes involved in cellular processes such as inflammation markers (il-1β, hmgb1, il-6, and tnf), apoptosis markers (caspase-3, caspase-8, bax, and p21), and autophagy markers (lamp2, atg5, becn1, and atg12). |
2022-06-06 |
2023-08-14 |
rat |
| Zhihan Tu, Liusiqiao Tang, Hang Yang, Xiaoming Zhang, Chao Jiang, Heding She. Effect of low-frequency noise on the survival rate and immunity of infected Vibrio parahaemolyticus sea slug (Onchidium reevesii). Fish & shellfish immunology. 2022-06-01. PMID:35643354. |
we found that after the infection with v. parahaemolyticus, the survival rate of the sea slugs decreased, the apoptosis rate and reactive oxygen species (ros) production of hemocytes increased significantly (p < 0.05), the proliferation of hemocytes accelerated, the activities of enzymes such as superoxide dismutase (sod), catalase (cat), alkaline phosphatase (akp), alanine transaminase (alt) and lysozyme (lzm) in the hepatopancreas increased significantly, and the expression of tnf signaling pathway-related genes (tnf-α, fadd, caspase 8, caspase 3) and hsp70 genes were generally upregulated. |
2022-06-01 |
2023-08-13 |
cat |
| Teresa Musumeci, Giulia Di Benedetto, Claudia Carbone, Angela Bonaccorso, Giovanni Amato, Maria Josè Lo Faro, Chiara Burgaletto, Giovanni Puglisi, Renato Bernardini, Giuseppina Cantarell. Intranasal Administration of a TRAIL Neutralizing Monoclonal Antibody Adsorbed in PLGA Nanoparticles and NLC Nanosystems: An In Vivo Study on a Mouse Model of Alzheimer's Disease. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625722. |
tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail), a proinflammatory cytokine belonging to the tnf superfamily, appears to be a key player in the inflammatory/immune orchestra of the ad brain. |
2022-05-28 |
2023-08-13 |
mouse |