| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Ren, Gedan Cui, Yongxiang Ga. Research progress on inflammatory mechanism of primary Sjögren syndrome. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 6. 2022-03-29. PMID:35347914. |
long-term inflammation leads to accelerated apoptosis of epithelial cells, disordered gland structure, increased expression of proinflammatory cytokine such as cxc subfamily ligand (cxcl) 12, cxcl13, b cell-activating factor (baf), interleukin (il)-6, interferon (ifn)-γ and tumor necrosis factor (tnf)-α in submandibular gland. |
2022-03-29 |
2023-08-13 |
Not clear |
| Bao Zhao, Qingyue Fan, Jintong Liu, Aihua Yin, Pingping Wang, Wenxin Zhan. Identification of Key Modules and Genes Associated with Major Depressive Disorder in Adolescents. Genes. vol 13. issue 3. 2022-03-25. PMID:35328018. |
several gene ontology (go) terms and kyoto encyclopedia of genes and genomes (kegg) pathways associated with stress and inflammation were identified in this module, including histone methylation, apoptosis, nf-kappa β signaling pathway, and tnf signaling pathway. |
2022-03-25 |
2023-08-13 |
human |
| Valéria Bumiller-Bini Hoch, Larissa Schneider, Anna Elisabeth Pumpe, Emelie Lüders, Jennifer Elisabeth Hundt, Angelica Beate Winter Bold. Marked to Die-Cell Death Mechanisms for Keratinocyte Acantholysis in Pemphigus Diseases. Life (Basel, Switzerland). vol 12. issue 3. 2022-03-25. PMID:35330080. |
among the molecules, most investigated were pleiotropic molecules such as tnf and casp3, followed by fasl and casp8, and then by fas, bax, bcl2, and tp53, all involved in more than one pathway but interpreted to function only within apoptosis. |
2022-03-25 |
2023-08-13 |
mouse |
| Liyuan Yi, Caiyun Sun, Jinying Wu, Zengxin Hou, Wensheng L. Molecular cloning, expressional analyses and functional identification of TRAIL in tilapia, Oreochromis niloticus. Journal of fish diseases. 2022-03-17. PMID:35298837. |
tnfsf10 (trail or apol-2) belongs to the tumour necrosis factor (tnf) cytokine family and induces rapid apoptosis in a wide variety of tumour cell lines upon binding to death-inducing signalling receptors. |
2022-03-17 |
2023-08-13 |
Not clear |
| Zhuohui Luo, Jiawen Huang, Ennian Li, Xinqian He, Qiqi Meng, Xinan Huang, Xiaoling Shen, Changkai Ya. An Integrated Pharmacology-Based Strategy to Investigate the Potential Mechanism of Xiebai San in Treating Pediatric Pneumonia. Frontiers in pharmacology. vol 13. 2022-03-03. PMID:35237157. |
il-17 signaling pathway, tnf signaling pathway and pi3k-akt signaling pathway, which are involved in anti-inflammation processes, immune responses and apoptosis, showed to be the most probable pathways regulated by xbs. |
2022-03-03 |
2023-08-13 |
Not clear |
| Murat Sevimli, Dilek Bayram, Meltem Özgöçmen, Ilkay Armağan, Tuğba Semerci Seviml. Boric acid suppresses cell proliferation by TNF signaling pathway mediated apoptosis in SW-480 human colon cancer line. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 71. 2022-02-27. PMID:35219976. |
boric acid suppresses cell proliferation by tnf signaling pathway mediated apoptosis in sw-480 human colon cancer line. |
2022-02-27 |
2023-08-13 |
human |
| Juhyun Shin, Arti Nile, Ramesh Kumar Saini, Jae-Wook O. Astaxanthin Sensitizes Low SOD2-Expressing GBM Cell Lines to TRAIL Treatment via Pathway Involving Mitochondrial Membrane Depolarization. Antioxidants (Basel, Switzerland). vol 11. issue 2. 2022-02-25. PMID:35204257. |
our study aimed to evaluate the effect of the well-known carotenoid 3, 3'-dihydroxy-β, β'-carotene-4, 4-dione (astaxanthin, axt) on glioblastoma multiforme (gbm) cells, especially as a pretreatment of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), that was previously shown to increase ros and to induce apoptosis in cancer cells. |
2022-02-25 |
2023-08-13 |
Not clear |
| Zhongyuan Zhou, Hongmei Chen, Yuanyuan Li, Qian Liu, Keyu Lu, Xiaoshan Zhu, You Wan. Transcriptome and biochemical analyses of rainbow trout (Oncorhynchus mykiss) RTG-2 gonadal cells in response to BDE-47 stress indicates effects on cell proliferation. Aquatic toxicology (Amsterdam, Netherlands). vol 245. 2022-02-21. PMID:35189508. |
mapping the kyoto encyclopedia of genes and genomes (kegg) database, p53, tumor necrosis factor (tnf), mitogen-activated protein kinase (mapk), phosphatidylinositide 3-kinase-akt (pi3k-akt), and reaction oxygen species (ros)-mediated signaling pathways were determined to be the major pathways involved in modulating the cell cycle and apoptosis. |
2022-02-21 |
2023-08-13 |
Not clear |
| О L Nosareva, E A Stepovaya, E V Shakhristova, R M Karpo. The Role of Redox Status Changes in Dexamethasone-Induced Apoptosis in Jurkat Tumor Cells. Bulletin of experimental biology and medicine. 2022-02-17. PMID:35175483. |
under conditions of dexamethasone-induced apoptosis, glutathione system blockage mostly affects presentation of tnf ri- and fas-receptors in jurkat tumor cells, as well as change in content of transcription factors apaf-1 and nf-κb, thereby promoting cell death. |
2022-02-17 |
2023-08-13 |
Not clear |
| Jingquan Ji, Ming Feng, Yan Huang, Xiaohong Ni. Liraglutide inhibits receptor for advanced glycation end products (RAGE)/reduced form of nicotinamide-adenine dinucleotide phosphate (NAPDH) signaling to ameliorate non-alcoholic fatty liver disease (NAFLD) in vivo and vitro. Bioengineered. vol 13. issue 3. 2022-02-15. PMID:35164657. |
in pa and h2o2-induced aml12 cells, liraglutide treatment was able to decrease cell apoptosis, ros levels and the levels of inflammatory factors including tumor necrosis factor (tnf)-α, interleukin (il)-1β and il-6, while it effects were reversed by the induction of rage overexpression or nox2 overexpression. |
2022-02-15 |
2023-08-13 |
mouse |
| Maria C Tanze. A proteomic perspective on TNF-mediated signalling and cell death. Biochemical Society transactions. 2022-02-15. PMID:35166321. |
these diseases generally display increased levels of cell death, which, downstream of the tnf receptor, can either be caspase-dependent (apoptosis) or caspase-independent (necroptosis). |
2022-02-15 |
2023-08-13 |
Not clear |
| Huihui Su, Guosong Wu, Lulu Zhan, Fei Xu, Huiqin Qian, Yanling Li, Ximei Zh. Exploration of the Mechanism of Lianhua Qingwen in Treating Influenza Virus Pneumonia and New Coronavirus Pneumonia with the Concept of "Different Diseases with the Same Treatment" Based on Network Pharmacology. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-02-11. PMID:35145559. |
amongst them, il-17, t cell receptor, th17 cell differentiation, tnf, toll-like receptor, mapk, apoptosis, and seven other signalling pathways were closely related to the occurrence and development of ncp and ivp. |
2022-02-11 |
2023-08-13 |
Not clear |
| Gisa Tiegs, Andrea K Hors. TNF in the liver: targeting a central player in inflammation. Seminars in immunopathology. 2022-02-05. PMID:35122118. |
in the liver, tnf induces numerous biological responses such as hepatocyte apoptosis and necroptosis, liver inflammation and regeneration, and autoimmunity, but also progression to hepatocellular carcinoma. |
2022-02-05 |
2023-08-13 |
Not clear |
| Ye Yang, Yin-Ping Liu, Wei Bao, Jun-Song Chen, Xiao-Wei X. RNA sequencing analysis reveals apoptosis induction by hydrogen treatment in endometrial cancer via TNF and NF-κB pathways. Translational cancer research. vol 9. issue 5. 2022-02-04. PMID:35117712. |
rna sequencing analysis reveals apoptosis induction by hydrogen treatment in endometrial cancer via tnf and nf-κb pathways. |
2022-02-04 |
2023-08-13 |
Not clear |
| Zhao Zhu, Guoxiu Zhang, Dahuan Li, Xiaojun Yin, Tianzhong Wan. Silencing of specificity protein 1 protects H9c2 cells against lipopolysaccharide-induced injury via binding to the promoter of chemokine CXC receptor 4 and suppressing NF-κB signaling. Bioengineered. vol 13. issue 2. 2022-01-20. PMID:35048778. |
moreover, silencing of sp1 or cxcr4 suppressed lps-induced inflammation and cell apoptosis in h9c2 cells, as evidenced by the increase in cell viability and decrease in lactate dehydrogenase release, interleukin (il)-6, il-8, and tumor necrosis factor (tnf)-α levels, and caspase-3 activity. |
2022-01-20 |
2023-08-13 |
Not clear |
| Wen-Wen Lu, Yi-Jing Qiu, Xiao-Fen Fan, Guo-You Yu, Guo-Lin W. [Mechanism of Huangqi Guizhi Wuwu Decoction in treatment of rheumatoid arthritis based on UPLC-LTQ-Orbitrap-MS, network pharmacology, and cell experiment]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994138. |
the results of uplc-ltq-orbitrap-ms, network pharmacology and cell experiment showed that the active components in hqgz may inhibit inflammatory response and regulate immune function and cell apoptosis by modulating key proteins in tnf signaling pathway to treat rheumatoid arthritis. |
2022-01-07 |
2023-08-13 |
Not clear |
| Jianhong Shi, Ruizhi Li, Yuanxiao Yang, Liting Ji, Changyu L. Protective effect of α-asarone and β-asarone on Aβ -induced inflammatory response in PC12 cells and its. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 5. 2022-01-05. PMID:34986541. |
the levels of inflammatory cytokines interleukin (il)-1, , tumor necrosis factor (tnf)-α, oxidation-related inducible nitric oxide synthase (inos), nitric oxide (no), apoptosis factors caspase-3 and p53 were detected by elisa method. |
2022-01-05 |
2023-08-13 |
Not clear |
| Yi Liu, Gang Tang, Jinyu L. Long non-coding RNA NEAT1 participates in ventilator-induced lung injury by regulating miR-20b expression. Molecular medicine reports. vol 25. issue 2. 2022-01-04. PMID:34981816. |
mouse and cell models were established to detect neat1 expression, pathological changes in lung tissues, apoptosis of ams, expression of the m1 phenotype marker, cd86 and m2 phenotype marker, cd206, and the expression levels of interleukin (il)‑1β, il‑6, tumor necrosis factor (tnf)‑α and inducible nitric oxide synthase (inos). |
2022-01-04 |
2023-08-13 |
mouse |
| Hongwei Lu, Yaqin Meng, Xinrui Han, Wei Zhan. ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury. Journal of healthcare engineering. vol 2021. 2021-12-27. PMID:34956566. |
in addition, adam8 can significantly induce cortical cell apoptosis in mcao mice, leading to the loss of neurons and the expression of proinflammatory factors cox2, inos, tnf |
2021-12-27 |
2023-08-13 |
mouse |
| Rittibet Yapasert, Patompong Khaw-On, Ratana Banjerdpongcha. Coronavirus Infection-Associated Cell Death Signaling and Potential Therapeutic Targets. Molecules (Basel, Switzerland). vol 26. issue 24. 2021-12-24. PMID:34946543. |
such signaling promotes viral survival, proliferation, and inflammation by inducing the expression of apoptosis inhibitors such as bcl-2 and xiap, as well as cytokines, e.g., tnf. |
2021-12-24 |
2023-08-13 |
Not clear |