| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valerio Giacomo Minero, Amina Khadjavi, Paola Costelli, Francesco Maria Baccino, Gabriella Bonell. JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells. International immunopharmacology. vol 17. issue 1. 2014-02-03. PMID:23751896. |
compared to other cell types, hepatocytes and hepatoma-derived cell lines are poorly susceptible to tnf-induced apoptosis, which is largely ascribed to activation of the prosurvival transcription factor nf-κb and can be overcome by associating tnf to low doses of protein synthesis inhibitors or other drugs. |
2014-02-03 |
2023-08-12 |
human |
| Xia Liu, Xue-mei Ji, Xi-ning Du, Xi-cui Zong, Ding-fang Liang, Li Ma, Hai-tao Wu, Shuang-quan Zhan. Molecular cloning, expression, bioinformatics analysis, and bioactivity of TNFSF13 (APRIL) in the South African clawed frog (Xenopus laevi): a new model to study immunological diseases. Omics : a journal of integrative biology. vol 17. issue 7. 2014-01-23. PMID:23829578. |
tnfsf13 is one of the tumor necrosis factor (tnf) superfamily members that plays important roles in immune homeostasis and proliferation or apoptosis of certain tumor cell lines. |
2014-01-23 |
2023-08-12 |
mouse |
| Jing Xu, Zhengfan Xu, Jun-Ying Zhou, Zhengping Zhuang, Enhua Wang, Julie Boerner, Gen Sheng W. Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. The Journal of biological chemistry. vol 288. issue 46. 2014-01-23. PMID:24100030. |
regulation of the src-pp2a interaction in tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis. |
2014-01-23 |
2023-08-12 |
Not clear |
| Su-Geun Lim, Kyoungho Suk, Won-Ha Le. Reverse signaling from LIGHT promotes pro-inflammatory responses in the human monocytic leukemia cell line, THP-1. Cellular immunology. vol 285. issue 1-2. 2014-01-20. PMID:24044961. |
light is a type ii transmembrane protein belonging to the tnf superfamily which is involved in co-stimulation of t cells or apoptosis in tumors. |
2014-01-20 |
2023-08-12 |
human |
| Divya Mehta, Charles L Raison, Bobbi J Woolwine, Ebrahim Haroon, Elisabeth B Binder, Andrew H Miller, Jennifer C Felge. Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression. Brain, behavior, and immunity. vol 31. 2014-01-16. PMID:23624296. |
responders also demonstrated inhibition of genes related to apoptosis through tnf signaling at 6 h and 24 h after infusion. |
2014-01-16 |
2023-08-12 |
Not clear |
| Jia Hui Wu, Hong Fang Wang, Zhi Cheng Wang, Kai Xu, Ya Li Qi, Jin Hua Li, Shou Liang Gong, Yang Liu, Ya Li. Conditionally replicating adenovirus combined with gene-targeted radiotherapy induces apoptosis via TRAIL death receptors in MDA-MB-231 cells. Molecular medicine reports. vol 8. issue 1. 2014-01-07. PMID:23708314. |
the expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail), death receptor 5 (dr5), caspase-3 and caspase-8 mrna was detected by quantitative polymerase chain reaction. |
2014-01-07 |
2023-08-12 |
Not clear |
| Keren Mizrahi, Nadir Askenas. Activation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture. American journal of stem cells. vol 2. issue 3. 2014-01-07. PMID:24396708. |
the current data reveal inductive crosstalk between tnf family receptors, which are largely dissociated from the sensitivity of hematopoietic progenitors to apoptosis. |
2014-01-07 |
2023-08-12 |
human |
| Keren Mizrahi, Nadir Askenas. Activation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture. American journal of stem cells. vol 2. issue 3. 2014-01-07. PMID:24396708. |
activation of fas, tnf and trail receptors and excessive apoptosis are not responsible for loss of engraftment and impaired reconstituting activity of ucb progenitors following extended culture. |
2014-01-07 |
2023-08-12 |
human |
| Kata Juhász, Agnes Zvara, Anna-Maria Lipp, Benedikt Nimmervoll, Alois Sonnleitner, Zsolt Balogi, Ernő Dud. Casein kinase 2-interacting protein-1, an inflammatory signaling molecule interferes with TNF reverse signaling in human model cells. Immunology letters. vol 152. issue 1. 2014-01-06. PMID:23583459. |
both tnf reverse signaling in thp-1 cells and expression of the n terminal fragment of mtnf in hek293 cells were found to induce apoptosis that could be prevented by overexpression of ckip-1. |
2014-01-06 |
2023-08-12 |
human |
| Kata Juhász, Agnes Zvara, Anna-Maria Lipp, Benedikt Nimmervoll, Alois Sonnleitner, Zsolt Balogi, Ernő Dud. Casein kinase 2-interacting protein-1, an inflammatory signaling molecule interferes with TNF reverse signaling in human model cells. Immunology letters. vol 152. issue 1. 2014-01-06. PMID:23583459. |
our findings demonstrate that ckip-1 activates pro-inflammatory pathways and interferes with tnf reverse signaling induced apoptosis in human model cells. |
2014-01-06 |
2023-08-12 |
human |
| Rahim Horuz, Cemal Göktaş, Cihangir A Çetinel, Oktay Akça, Hasan Aydın, Işın D Ekici, Selami Albayrak, Kemal Sarıc. Role of TNF-associated cytokines in renal tubular cell apoptosis induced by hyperoxaluria. Urolithiasis. vol 41. issue 3. 2014-01-06. PMID:23595894. |
our results indicate that apoptosis induced by oxalate is possibly mediated via tnf and fas pathways. |
2014-01-06 |
2023-08-12 |
rat |
| Ji-Min Jeong, Ju-Won Kim, Hyoung-Jun Park, Jeong-Hun Song, Do-Hyung Kim, Chan-Il Par. Molecular cloning and characterisation of the rock bream, Oplegnathus fasciatus, Fas (CD95/APO-1), and its expression analysis in response to bacterial or viral infection. Results in immunology. vol 1. issue 1. 2013-12-27. PMID:24371547. |
fas belongs to the tumour necrosis factor (tnf) receptor superfamily and can transmit a death signal leading to apoptosis. |
2013-12-27 |
2023-08-12 |
Not clear |
| An-Sheng Lee, Guei-Jane Wang, Hua-Chen Chan, Fang-Yu Chen, Chia-Ming Chang, Chao-Yuh Yang, Yuan-Teh Lee, Kuan-Cheng Chang, Chu-Huang Che. Electronegative low-density lipoprotein induces cardiomyocyte apoptosis indirectly through endothelial cell-released chemokines. Apoptosis : an international journal on programmed cell death. vol 17. issue 9. 2013-12-23. PMID:22562555. |
addition of recombinant lix or il-8 to ccm-free cardiomyocyte cultures increased apoptosis and enhanced production of tumor necrosis factor (tnf)-α and il-1β by increasing the translocation of nf-κb into the nucleus; these effects were attenuated by inhibiting pi3k and cxcr2. |
2013-12-23 |
2023-08-12 |
human |
| Mei Chung Moh, Paolo Alberto Lorenzini, Charles Gullo, Herbert Schwar. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 8. 2013-12-16. PMID:23620528. |
using the human monocytic thp-1 cell line, we demonstrate that engagement of cd137l by recombinant cd137 protein promotes cell adhesion, apoptosis, expression of cd14, and production of il-8 and tumor necrosis factor (tnf). |
2013-12-16 |
2023-08-12 |
human |
| Shan Li, Li Zhang, Qing Yao, Lin Li, Na Dong, Jie Rong, Wenqing Gao, Xiaojun Ding, Liming Sun, Xing Chen, She Chen, Feng Sha. Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains. Nature. vol 501. issue 7466. 2013-12-11. PMID:23955153. |
nleb glcnacylation (the addition of glcnac onto a protein side chain) of death domains blocked homotypic/heterotypic death domain interactions and assembly of the oligomeric tnfr1 complex, thereby disrupting tnf signalling in epec-infected cells, including nf-κb signalling, apoptosis and necroptosis. |
2013-12-11 |
2023-08-12 |
mouse |
| M Concepción Izquierdo, Ana B Sanz, M Dolores Sánchez-Niño, M Vanessa Pérez-Gómez, Marta Ruiz-Ortega, Jonay Poveda, Olga Ruiz-Andrés, Adrián M Ramos, Juan A Moreno, Jesús Egido, Alberto Orti. Acute kidney injury transcriptomics unveils a relationship between inflammation and ageing. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia. vol 32. issue 6. 2013-12-05. PMID:23093094. |
fn14 is the receptor for tumor necrosis factor-like weak inducer of apoptosis (tweak), a member of the tnf superfamily. |
2013-12-05 |
2023-08-12 |
Not clear |
| Nima Etemadi, Jessica K Holien, Diep Chau, Grant Dewson, James M Murphy, Warren S Alexander, Michael W Parker, John Silke, Ueli Nachbu. Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor. The FEBS journal. vol 280. issue 21. 2013-12-05. PMID:23815148. |
to determine whether there were any functional differences in the ability of tnf and ltα3 to induce tnfr1-dependent apoptosis or necroptosis, and if there were different requirements for ciaps and sharpin to transmit the tnfr1 signal, we compared the ability of cells to respond to tnf and ltα3. |
2013-12-05 |
2023-08-12 |
mouse |
| Li-Xiu Zhu, Hai-Hong Zhang, Yi-Fang Mei, Yan-Ping Zhao, Zhi-Yi Zhan. Role of tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducible 14 (Fn14) axis in rheumatic diseases. Chinese medical journal. vol 125. issue 21. 2013-11-19. PMID:23106895. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a member of the tnf superfamily of structurally related cytokines and is known to induce proliferation, migration, differentiation, apoptotic cell death, inflammation, and angiogenesis. |
2013-11-19 |
2023-08-12 |
Not clear |
| Chuan Sun, Xiao-Xin Li, Xiang-Jun He, Qi Zhang, Yong Ta. Neuroprotective effect of minocycline in a rat model of branch retinal vein occlusion. Experimental eye research. vol 113. 2013-11-07. PMID:23748101. |
the expressional levels of apoptosis related genes (bax, bcl-2) and inflammation related genes (il-1 β, tnf α, mcp-1 and ccr2) were measured by real-time pcr, the results showed that minocycline treatment upregulated bcl-2 expression and inhibits tnf α expression since early stage of brvo. |
2013-11-07 |
2023-08-12 |
rat |
| Melania Balzarolo, Carsten Watzl, Jan Paul Medema, Monika C Wolker. NAB2 and EGR-1 exert opposite roles in regulating TRAIL expression in human Natural Killer cells. Immunology letters. vol 151. issue 1-2. 2013-10-22. PMID:23416169. |
we have previously shown that nab2 modulates the levels of expression of the tumor necrosis factor (tnf) family member tnf-related apoptosis inducing ligand (trail) in t cells and plasmacytoid dcs. |
2013-10-22 |
2023-08-12 |
human |