| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhang Peng, Yue Shuangzhu, Jiang Yongjie, Zhang Xinjun, Liu Yin. TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. Molecular and cellular biochemistry. vol 377. issue 1-2. 2013-09-13. PMID:23358926. |
tnf receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. |
2013-09-13 |
2023-08-12 |
human |
| Vladimira Horova, Nada Hradilova, Iva Jelinkova, Michal Koc, Jan Svadlenka, Jan Brazina, Martin Klima, Josef Slavik, Alena Hyrslova Vaculova, Ladislav Ander. Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes. The FEBS journal. vol 280. issue 14. 2013-09-11. PMID:23678861. |
tumour necrosis factor (tnf) related apoptosis inducing ligand (trail), a membrane-bound ligand from the tnf family, has attracted significant attention due to its rather specific and effective ability to induce apoptotic death in various types of cancer cells via binding to and activating its pro-apoptotic death receptors. |
2013-09-11 |
2023-08-12 |
Not clear |
| B A Abhari, S Cristofanon, R Kappler, D von Schweinitz, R Humphreys, S Fuld. RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex. Oncogene. vol 32. issue 27. 2013-09-06. PMID:22890322. |
in contrast, overexpression of the dominant-negative superrepressor iκbα-sr or addition of the tumor necrosis factor (tnf)α-blocking antibody enbrel do not interfere with cotreatment-induced apoptosis, pointing to a nuclear factor-κb- and tnfα-independent mechanism. |
2013-09-06 |
2023-08-12 |
Not clear |
| Diego De Miguel, Gorka Basáñez, Diego Sánchez, Patricia Galán Malo, Isabel Marzo, Luis Larrad, Javier Naval, Julián Pardo, Alberto Anel, Luis Martinez-Losta. Liposomes decorated with Apo2L/TRAIL overcome chemoresistance of human hematologic tumor cells. Molecular pharmaceutics. vol 10. issue 3. 2013-09-04. PMID:23331277. |
human apo2-ligand/trail is a member of the tnf cytokine superfamily capable of inducing apoptosis on tumor cells while sparing normal cells. |
2013-09-04 |
2023-08-12 |
human |
| Jinbo Han, Rossana C Soletti, Anil Sadarangani, Priya Sridevi, Michael E Ramirez, Lars Eckmann, Helena L Borges, Jean Y J Wan. Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Molecular cancer research : MCR. vol 11. issue 3. 2013-09-03. PMID:23339186. |
because tnf also activates caspase-8, selective inhibition of tnf-induced extrinsic apoptosis would be required for inflammation-associated tumor growth. |
2013-09-03 |
2023-08-12 |
mouse |
| Jinbo Han, Rossana C Soletti, Anil Sadarangani, Priya Sridevi, Michael E Ramirez, Lars Eckmann, Helena L Borges, Jean Y J Wan. Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Molecular cancer research : MCR. vol 11. issue 3. 2013-09-03. PMID:23339186. |
in contrast, tnf did not induce rb cleavage in colon cancer cells expressing nuclear β-catenin and these cells could be sensitized to basal and/or tnf-induced apoptosis by the knockdown of β-catenin or rb. |
2013-09-03 |
2023-08-12 |
mouse |
| Liying Gu, Lan Dai, Cong Cao, Jing Zhu, Chuanwei Ding, Hai-Bo Xu, Lihua Qiu, Wen D. Functional expression of TWEAK and the receptor Fn14 in human malignant ovarian tumors: possible implication for ovarian tumor intervention. PloS one. vol 8. issue 3. 2013-08-27. PMID:23469193. |
the aim of this current study was to investigate the expression of the tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) and its receptor fibroblast growth factor-inducible 14 (fn14) in human malignant ovarian tumors, and test tweak's potential role on tumor progression in cell models in-vitro. |
2013-08-27 |
2023-08-12 |
human |
| Xiaojie Liu, Mingshan Wang, Huailong Chen, Yunliang Guo, Fuguo Ma, Fei Shi, Yanlin Bi, Ying L. Hypothermia protects the brain from transient global ischemia/reperfusion by attenuating endoplasmic reticulum response-induced apoptosis through CHOP. PloS one. vol 8. issue 1. 2013-08-20. PMID:23301071. |
hypothermia blocked the tnf or fas-mediated extrinsic apoptosis pathway and the mitochondria pathway of apoptosis, however, whether hypothermia can block endoplasmic reticulum mediated apoptosis is never known. |
2013-08-20 |
2023-08-12 |
rat |
| B M Tan, N W Zammit, A O Yam, R Slattery, S N Walters, E Malle, S T Gre. Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells. Diabetologia. vol 56. issue 3. 2013-08-19. PMID:23250032. |
here, we investigated the function of baculoviral inhibitors of apoptosis repeat containing (birc) proteins in regulating tnf signalling cascades. |
2013-08-19 |
2023-08-12 |
mouse |
| Seok-Joo Kim, Hyun-Ae Eum, Timothy R Billiar, Sun-Mee Le. Role of heme oxygenase 1 in TNF/TNF receptor-mediated apoptosis after hepatic ischemia/reperfusion in rats. Shock (Augusta, Ga.). vol 39. issue 4. 2013-08-19. PMID:23423194. |
the binding of tumor necrosis factor (tnf) to tnf receptor 1 (tnfr1) leads to the formation of a death-inducing signaling complex (disc), which subsequently initiates a caspase cascade resulting in apoptosis. |
2013-08-19 |
2023-08-12 |
rat |
| Ingvild Pettersen, Ninib Baryawno, Frida Abel, Wenche Helen Bakkelund, Svetlana N Zykova, Jan-Olof Winberg, Ugo Moens, Agnes Rasmuson, Per Kogner, John Inge Johnsen, Baldur Sveinbjörnsso. Expression of TWEAK/Fn14 in neuroblastoma: implications in tumorigenesis. International journal of oncology. vol 42. issue 4. 2013-08-19. PMID:23443741. |
tumor necrosis factor-like weak inducer of apoptosis (tweak), a member of the tumor necrosis factor (tnf) family of cytokines, acts on responsive cells via binding to a cell surface receptor called fn14. |
2013-08-19 |
2023-08-12 |
Not clear |
| Xuemei Ji, Xia Liu, Lu Zhao, Chunyan Wang, Xingzhou Xu, Lin Yang, Xianwei Cui, Hongxin Ai, Jie Zhang, Jianfeng Li, Shuangquan Zhan. Molecular characterization, expression and binding activity of the cytokines TNFSF14 and its receptor LTBR in Oryctolagus cuniculus (rabbit). Molecular immunology. vol 54. issue 3-4. 2013-08-12. PMID:23370464. |
tnfsf14 is one of the most important tnf superfamily cytokines playing roles in lymphocyte homeostasis by enhancing effector cell activation and survival, or by cellular elimination through apoptosis. |
2013-08-12 |
2023-08-12 |
human |
| Shishir Shishodi. Molecular mechanisms of curcumin action: gene expression. BioFactors (Oxford, England). vol 39. issue 1. 2013-08-05. PMID:22996381. |
curcumin regulates the expression of inflammatory cytokines (e.g., tnf, il-1), growth factors (e.g., vegf, egf, fgf), growth factor receptors (e.g., egfr, her-2, ar), enzymes (e.g., cox-2, lox, mmp9, mapk, mtor, akt), adhesion molecules (e.g., elam-1, icam-1, vcam-1), apoptosis related proteins (e.g., bcl-2, caspases, dr, fas), and cell cycle proteins (e.g., cyclin d1). |
2013-08-05 |
2023-08-12 |
Not clear |
| Jianru Shi, Bingbing Jiang, Yiling Qiu, Jian Guan, Mohit Jain, Xin Cao, Michael Bauer, Lihe Su, Linda C Burkly, Teresa C Leone, Daniel P Kelly, Ronglih Lia. PGC1α plays a critical role in TWEAK-induced cardiac dysfunction. PloS one. vol 8. issue 1. 2013-08-02. PMID:23342071. |
we have recently found the cytokine tweak (tumor necrosis factor (tnf)-like weak inducer of apoptosis), a member of the tnf superfamily, to be increased in patients with cardiomyopathy and result in the development of heart failure when overexpressed in mice. |
2013-08-02 |
2023-08-12 |
mouse |
| L Xiang, C W Stephen Sze, T B Ng, Y Tong, P C Shaw, C W Sydney Tang, Y B Kalin Zhan. Polysaccharides of Dendrobium officinale inhibit TNF-α-induced apoptosis in A-253 cell line. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. vol 62. issue 3. 2013-07-30. PMID:23266598. |
in the present study, we further investigated the protective effect of dp on a human salivary gland cell line a-253 against tumor necrosis factor (tnf)-α-induced apoptosis. |
2013-07-30 |
2023-08-12 |
human |
| Dong-Hui Zhou, Li-Na Yang, Christian Roder, Holger Kalthoff, Anna Trauzol. TRAIL-induced expression of uPA and IL-8 strongly enhanced by overexpression of TRAF2 and Bcl-xL in pancreatic ductal adenocarcinoma cells. Hepatobiliary & pancreatic diseases international : HBPD INT. vol 12. issue 1. 2013-07-30. PMID:23392805. |
the death ligand, tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), induces apoptosis and non-apoptotic signaling in some tumor cells. |
2013-07-30 |
2023-08-12 |
Not clear |
| Jinbo Han, Priya Sridevi, Michael Ramirez, Kirsten J Ludwig, Jean Y J Wan. β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells. Molecular biology of the cell. vol 24. issue 4. 2013-07-25. PMID:23264463. |
we show here that activated β-catenin is required to suppress caspase-8 activation, but only in colon cancer cells that are resistant to tumor necrosis factor-α (tnf)-induced apoptosis. |
2013-07-25 |
2023-08-12 |
mouse |
| Jinbo Han, Priya Sridevi, Michael Ramirez, Kirsten J Ludwig, Jean Y J Wan. β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells. Molecular biology of the cell. vol 24. issue 4. 2013-07-25. PMID:23264463. |
in a mouse model of inflammation-associated colon tumors, we found nuclear expression of β-catenin, resistance to tnf-induced apoptosis, and reactivation of apoptosis in vivo after cotreatment of tnf with a v-atpase inhibitor. |
2013-07-25 |
2023-08-12 |
mouse |
| Shuichi Sato, Yuji Ogura, Vivek Mishra, Jonghyun Shin, Shephali Bhatnagar, Bradford G Hill, Ashok Kuma. TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity. Skeletal muscle. vol 3. issue 1. 2013-07-16. PMID:23835416. |
proinflammatory cytokine tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) and its receptor fn14 are the major regulators of skeletal muscle mass in many catabolic conditions. |
2013-07-16 |
2023-08-12 |
Not clear |
| Tiziana Bachetti, Sabrina Chiesa, Patrizio Castagnola, Daniele Bani, Eleonora Di Zanni, Alessia Omenetti, Andrea D'Osualdo, Alessandro Fraldi, Andrea Ballabio, Roberto Ravazzolo, Alberto Martini, Marco Gattorno, Isabella Ceccherin. Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS). Annals of the rheumatic diseases. vol 72. issue 6. 2013-07-12. PMID:23117241. |
tumour necrosis factor (tnf) receptor-associated periodic syndrome (traps) is caused by tnfrsf1a mutations, known to induce intracellular retention of the tnfα receptor 1 (tnfr1) protein, defective tnfα-induced apoptosis, and production of reactive oxygen species. |
2013-07-12 |
2023-08-12 |
Not clear |