| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feng Wang, Hongyan Hou, Lingqing Xu, Munanie Jane, Jing Peng, Yanjun Lu, Yaowu Zhu, Ziyong Su. Tim-3 signaling pathway as a novel negative mediator in lipopolysaccharide-induced endotoxic shock. Human immunology. vol 75. issue 5. 2014-11-26. PMID:24561184. |
in vitro administration of tim-3 blocking antibody restored the release of ifn-γ from splenocytes and decreased splenocyte apoptosis, and increased levels of ifn-γ and tumor necrosis factor (tnf)-α were also detected in septic mice at 24h post in vivo administration of the antibody. |
2014-11-26 |
2023-08-12 |
mouse |
| Ingrid A M van Roosmalen, Wim J Quax, Frank A E Kruy. Two death-inducing human TRAIL receptors to target in cancer: similar or distinct regulation and function? Biochemical pharmacology. vol 91. issue 4. 2014-11-21. PMID:25150214. |
the emergence during evolution of two tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) receptors, receptor-1/dr4 and -2/dr5, able to induce apoptosis has raised the question whether they differ in function and regulation, which is of key importance for selecting either dr4 or dr5 selective pro-apoptotic agents for cancer treatment. |
2014-11-21 |
2023-08-13 |
human |
| Sumit Kumar Hira, Indrani Mondal, Debasis Bhattacharya, Partha Pratim Mann. Downregulation of endogenous STAT3 augments tumoricidal activity of interleukin 15 activated dendritic cell against lymphoma and leukemia via TRAIL. Experimental cell research. vol 327. issue 2. 2014-11-18. PMID:25139620. |
in this study, we describe that the murine dcs upon stimulation with recombinant il-15 in vitro or in vivo, expresses tnf superfamily member trail which mediates cytotoxicity and growth inhibition against a murine lymphoma called dalton lymphoma (dl) via apoptosis. |
2014-11-18 |
2023-08-13 |
mouse |
| Elizabeth E Sweeney, Ping Fan, V Craig Jorda. Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells. International journal of oncology. vol 44. issue 5. 2014-11-13. PMID:24604139. |
tumor necrosis factor (tnf) family member activation is also essential for e(2)-induced apoptosis to occur in mcf-7:2a cells; upregulation of tnfα occurs simultaneously with oxidative stress activation. |
2014-11-13 |
2023-08-12 |
Not clear |
| Kristyn Dunlop, Kiranjot Gosal, Crystal Kantores, Julijana Ivanovska, Rupinder Dhaliwal, Jean-François Desjardins, Kim A Connelly, Amish Jain, Patrick J McNamara, Robert P Janko. Therapeutic hypercapnia prevents inhaled nitric oxide-induced right-ventricular systolic dysfunction in juvenile rats. Free radical biology & medicine. vol 69. 2014-11-08. PMID:24423485. |
inhaled nitric oxide-mediated increases in rv peroxynitrite, apoptosis, and contents of tumor necrosis factor (tnf)-α, interleukin (il)-1α, and nos-2 were all attenuated by therapeutic hypercapnia. |
2014-11-08 |
2023-08-12 |
rat |
| Undine Meusch, Maria Klingner, Christoph Baerwald, Manuela Rossol, Ulf Wagne. Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition. Arthritis research & therapy. vol 15. issue 6. 2014-11-04. PMID:24354986. |
deficient spontaneous in vitro apoptosis and increased tmtnf reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to tnf inhibition. |
2014-11-04 |
2023-08-12 |
Not clear |
| Undine Meusch, Maria Klingner, Christoph Baerwald, Manuela Rossol, Ulf Wagne. Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition. Arthritis research & therapy. vol 15. issue 6. 2014-11-04. PMID:24354986. |
in vitro apoptosis of peripheral monocytes in rheumatoid arthritis (ra) is disturbed and influenced by cytokine production and transmembrane tnf (tmtnf) reverse signaling. |
2014-11-04 |
2023-08-12 |
Not clear |
| Janjuree Netsawang, Jutatip Panaampon, Sasiprapa Khunchai, Suwattanee Kooptiwut, Amar Nagila, Chunya Puttikhunt, Pa-Thai Yenchitsomanus, Thawornchai Limjindapor. Dengue virus disrupts Daxx and NF-κB interaction to induce CD137-mediated apoptosis. Biochemical and biophysical research communications. vol 450. issue 4. 2014-11-04. PMID:25019989. |
the liberated nf-κb activated the promoter of cd137, which is a member of the tnf family, and is previously shown to induce apoptosis during denv infection. |
2014-11-04 |
2023-08-13 |
Not clear |
| Arash Nazeri, Pouria Heydarpour, Shokufeh Sadaghiani, Mohammad Ali Sahraian, Linda C Burkly, Amit Bar-O. A further TWEAK to multiple sclerosis pathophysiology. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:23873135. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a member of the tnf super family that controls many cellular activities including proliferation, migration, differentiation, apoptosis, and inflammation by binding to fibroblast growth factor-inducible 14 (fn14), a highly inducible cell surface receptor. |
2014-10-27 |
2023-08-12 |
Not clear |
| Jianqiang Mao, Zhiqian Lv, Yu Zhuan. MicroRNA-23a is involved in tumor necrosis factor-α induced apoptosis in mesenchymal stem cells and myocardial infarction. Experimental and molecular pathology. vol 97. issue 1. 2014-10-22. PMID:24269648. |
using a tumor necrosis factor (tnf)-α-induced bone marrow (bm)-msc injury model in vitro and a rat mi model in vivo, we showed in the current study that mir-23a was involved in tnf-α-induced bm-msc apoptosis through regulating caspase-7 and that the injection of bm-mscs overexpressing mir-23a could improve left ventricular (lv) function and reduce infarct size in the rat mi model. |
2014-10-22 |
2023-08-12 |
rat |
| Shuli Fan, Xu Li, Jie Lin, Sijiao Chen, Jinhua Shan, Guoxian Q. Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis. Inflammation. vol 37. issue 1. 2014-10-16. PMID:23933846. |
this study aims to investigate the effects of honokiol on proliferation, cell cycle, and apoptosis in tumor necrosis factor (tnf)-α-induced rat aortic smooth muscle cells (rasmcs). |
2014-10-16 |
2023-08-12 |
rat |
| Amit Kumar, Wasim Abbas, Georges Herbei. TNF and TNF receptor superfamily members in HIV infection: new cellular targets for therapy? Mediators of inflammation. vol 2013. 2014-10-14. PMID:24453421. |
tumor necrosis factor (tnf) and tnf receptors (tnfr) superfamily members are engaged in diverse cellular phenomena such as cellular proliferation, morphogenesis, apoptosis, inflammation, and immune regulation. |
2014-10-14 |
2023-08-12 |
Not clear |
| Ye Tian, Tianzhu Tao, Jiali Zhu, Yun Zou, Jiafeng Wang, Jinbao Li, Lulong Bo, Xiaoming Den. Soluble tumor necrosis factor related apoptosis inducing ligand level as a predictor of severity of sepsis and the risk of mortality in septic patients. PloS one. vol 8. issue 12. 2014-10-12. PMID:24349222. |
tumor necrosis factor related apoptosis inducing ligand (trail) as a member of the tnf gene superfamily induces apoptosis primarily in tumor cells. |
2014-10-12 |
2023-08-12 |
Not clear |
| Fuminori Taniguchi, Hiroko Higaki, Masao Izawa, Yukihiro Azuma, Eriko Hirakawa, Imari Deura, Tomio Iwabe, Kohkichi Hata, Tasuku Harad. The cellular inhibitor of apoptosis protein-2 is a possible target of novel treatment for endometriosis. American journal of reproductive immunology (New York, N.Y. : 1989). vol 71. issue 3. 2014-10-06. PMID:24382102. |
how is the tumor necrosis factor (tnf) α-induced inhibitor of apoptosis (iap) protein expression in endometriotic stromal cells (escs) involved in cell viability and signaling pathways? |
2014-10-06 |
2023-08-12 |
Not clear |
| Zhuling Qu, He Dong, Xiaolin Xu, Wei Feng, Xuanlong Y. Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway. Diagnostic pathology. vol 8. 2014-09-29. PMID:23635099. |
the tumor necrosis factor (tnf) and the cellular nf-κb pathway protein ikkβ play important roles in various cellular processes such as cell proliferation, survival, differentiation, and apoptosis. |
2014-09-29 |
2023-08-12 |
Not clear |
| Sharron A N Brown, Emily Cheng, Mark S Williams, Jeffrey A Winkle. TWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domain. PloS one. vol 8. issue 6. 2014-09-29. PMID:23750247. |
the tumor necrosis factor (tnf) superfamily member tnf-like weak inducer of apoptosis (tweak) is a pro-inflammatory and pro-angiogenic cytokine implicated in physiological tissue regeneration and wound repair. |
2014-09-29 |
2023-08-12 |
Not clear |
| Thorsten Braun, Pierre Fenau. Myelodysplastic Syndromes (MDS) and autoimmune disorders (AD): cause or consequence? Best practice & research. Clinical haematology. vol 26. issue 4. 2014-09-29. PMID:24507810. |
increased release of inflammatory cytokines like tumor necrosis factor-(tnf)-α and interferon (if)-γ triggers apoptosis of myeloid precursor cells leading to cytopenias. |
2014-09-29 |
2023-08-12 |
Not clear |
| Keren Mizrahi, Nadir Askenas. Physiological functions of TNF family receptor/ligand interactions in hematopoiesis and transplantation. Blood. vol 124. issue 2. 2014-09-25. PMID:24859365. |
secretion of ligands of the tumor necrosis factor (tnf) superfamily is a conserved response of parenchymal tissues to injury and inflammation that commonly perpetuates elimination of dysfunctional cellular components by apoptosis. |
2014-09-25 |
2023-08-13 |
Not clear |
| Chang-Chun Zhang, Guo-Peng Cui, Jian-Guo Hu, Yu-Zhou Xiao, Xin-She Zhou, Chen Shao, Qinghua Lin, Jian-Sheng Zho. Effects of adenoviral vector expressing hIGF-1 on apoptosis in nucleus pulposus cells in vitro. International journal of molecular medicine. vol 33. issue 2. 2014-09-18. PMID:24337543. |
it has been shown that the pro-inflammatory cytokine tumour necrosis factor (tnf)-α can induce disc cell apoptosis. |
2014-09-18 |
2023-08-12 |
human |
| William J Kaiser, Lisa P Daley-Bauer, Roshan J Thapa, Pratyusha Mandal, Scott B Berger, Chunzi Huang, Aarthi Sundararajan, Hongyan Guo, Linda Roback, Samuel H Speck, John Bertin, Peter J Gough, Siddharth Balachandran, Edward S Mocarsk. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 21. 2014-09-02. PMID:24821786. |
in the face of complete rip1 deficiency, cells develop sensitivity to rip3-mixed lineage kinase domain-like-mediated necroptosis as well as to casp8-mediated apoptosis activated by diverse innate immune stimuli (e.g., tnf, ifn, double-stranded rna). |
2014-09-02 |
2023-08-13 |
mouse |