Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Marco de Bruyn, Valerie R Wiersma, Wijnand Helfrich, Paul Eggleton, Edwin Breme. The ever-expanding immunomodulatory role of calreticulin in cancer immunity. Frontiers in oncology. vol 5. 2015-03-09. PMID:25750898. |
interestingly, treatment with tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) also induces membrane calreticulin exposure on cancer cells. |
2015-03-09 |
2023-08-13 |
Not clear |
Pierre-François Cartron, Elise Petit, Grégory Bellot, Lisa Oliver, François M Vallett. Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis. Cellular signalling. vol 26. issue 9. 2015-03-03. PMID:24794530. |
metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for bak activation during tnf alpha triggered apoptosis. |
2015-03-03 |
2023-08-13 |
Not clear |
Dongxiao Dong, Jing Gao, Ying Sun, Yuqing Long, Meng Li, Dongchao Zhang, Jianfang Gong, Liang Xu, Liuan Li, Shunyi Qin, Jifei Ma, Tianming Ji. Adenovirus-mediated co-expression of the TRAIL and HN genes inhibits growth and induces apoptosis in Marek's disease tumor cell line MSB-1. Cancer cell international. vol 15. 2015-03-02. PMID:25729329. |
the objective of this study was to determine the in vitro tumor-inhibitory effect of a recombinant adenovirus expressing a fusion protein of tumor necrosis factor (tnf) related apoptosis inducing ligand (trail) and hemagglutinin-neuraminidase (hn) genes on the msb-1 marek's disease tumor cell line. |
2015-03-02 |
2023-08-13 |
Not clear |
Jackeline Agorreta, Jianting Hu, Dongxia Liu, Domenico Delia, Helen Turley, David J P Ferguson, Francisco Iborra, María J Pajares, Marta Larrayoz, Isabel Zudaire, Ruben Pio, Luis M Montuenga, Adrian L Harris, Kevin Gatter, Francesco Pezzell. TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Molecular cancer research : MCR. vol 12. issue 5. 2015-02-27. PMID:24567527. |
the tnf receptor-associated protein 1 (trap1) is a mitochondrial hsp that has been related to drug resistance and protection from apoptosis in colorectal and prostate cancer. |
2015-02-27 |
2023-08-12 |
Not clear |
Sung-Min Hwang, MeiHong Jin, Yong Hwan Shin, Seul Ki Choi, Eun Namkoong, MinKyoung Kim, Moon-Yong Park, Kyungpyo Par. Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells. Experimental & molecular medicine. vol 46. 2015-02-20. PMID:25502757. |
in addition, based on data suggesting that tumor necrosis factor (tnf)-α induces cell apoptosis, lpa upregulates tnf-induced caspase-3 and cleaved poly(adp-ribose)polymerase (parp). |
2015-02-20 |
2023-08-13 |
Not clear |
Luisa Costa, Francesco Caso, Mariangela Atteno, Antonio Del Puente, Md Abud Darda, Paolo Caso, Augusta Ortolan, Ugo Fiocco, Roberta Ramonda, Leonardo Punzi, Raffaele Scarp. Impact of 24-month treatment with etanercept, adalimumab, or methotrexate on metabolic syndrome components in a cohort of 210 psoriatic arthritis patients. Clinical rheumatology. vol 33. issue 6. 2015-02-13. PMID:23959447. |
tumor necrosis factor (tnf)-α is a pro-inflammatory adipocytokine mainly produced by monocytes and macrophages with a central role in inflammatory responses, but it also induces adipocytes apoptosis, promotes insulin resistance, and stimulates lipolysis. |
2015-02-13 |
2023-08-12 |
Not clear |
Ji-Hyun Park, Woo-Ram Lee, Hyun-Soo Kim, Sang-Mi Han, Young-Chae Chang, Kwan-Kyu Par. Protective effects of melittin on tumor necrosis factor-α induced hepatic damage through suppression of apoptotic pathway and nuclear factor-kappa B activation. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 12. 2015-02-10. PMID:24872433. |
in the present study, we investigated the anti-apoptotic effect of melittin on tumor necrosis factor (tnf)-α/actinomycin (act) d-induced apoptosis in hepatocytes. |
2015-02-10 |
2023-08-13 |
bee |
Eiji Kobayashi, Hiroyuki Kishi, Tatsuhiko Ozawa, Hiroshi Hamana, Hidetoshi Nakagawa, Aishun Jin, Zhezhu Lin, Atsushi Muraguch. A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells. Biochemical and biophysical research communications. vol 453. issue 4. 2015-02-09. PMID:25445592. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and its associated receptors (trail-r/tr) are attractive targets for cancer therapy because trail induces apoptosis in tumor cells through tr while having little cytotoxicity on normal cells. |
2015-02-09 |
2023-08-13 |
human |
Jiřina Hofmanová, Nicol Straková, Alena Hyršlová Vaculová, Zuzana Tylichová, Barbora Safaříková, Belma Skender, Alois Kozubí. Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer. Mediators of inflammation. vol 2014. 2015-02-07. PMID:24876678. |
cytokines from the tnf family (tnf- α, trail, and fasl) have potent inflammatory activities and can also regulate apoptosis, which plays an important role in cancer development. |
2015-02-07 |
2023-08-13 |
Not clear |
Jiřina Hofmanová, Nicol Straková, Alena Hyršlová Vaculová, Zuzana Tylichová, Barbora Safaříková, Belma Skender, Alois Kozubí. Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer. Mediators of inflammation. vol 2014. 2015-02-07. PMID:24876678. |
the results of our own research showed enhancement of apoptosis in colon cancer cells by a combination of either docosahexaenoic acid (dha) or butyrate with tnf family cytokines, especially by promotion of the mitochondrial apoptotic pathway and modulation of nf κ b activity. |
2015-02-07 |
2023-08-13 |
Not clear |
Musarat Ishaq, Shailesh Kumar, Hilal Varinli, Zhao Jun Han, Amanda E Rider, Margaret D M Evans, Anthony B Murphy, Kostya Ostriko. Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Molecular biology of the cell. vol 25. issue 9. 2015-02-02. PMID:24574456. |
by screening genes involved in apoptosis, we identify tumor necrosis factor (tnf)-family members as the most differentially expressed cellular genes upon agp treatment of melanoma cells. |
2015-02-02 |
2023-08-12 |
Not clear |
Musarat Ishaq, Shailesh Kumar, Hilal Varinli, Zhao Jun Han, Amanda E Rider, Margaret D M Evans, Anthony B Murphy, Kostya Ostriko. Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Molecular biology of the cell. vol 25. issue 9. 2015-02-02. PMID:24574456. |
tnf receptor 1 (tnfr1) antagonist-neutralizing antibody specifically inhibits agp-induced apoptosis signal, regulating apoptosis signal-regulating kinase 1 (ask1) activity and subsequent ask1-dependent apoptosis. |
2015-02-02 |
2023-08-12 |
Not clear |
A Marivin, J Berthelet, J Cartier, C Paul, S Gemble, A Morizot, W Boireau, M Saleh, J Bertoglio, E Solary, L Dubre. cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation. Oncogene. vol 33. issue 48. 2015-01-21. PMID:24276241. |
tnf receptor engagement induces the formation of a multimolecular complex including the tnfr-associated factor traf2, the receptor-interaction protein kinase rip1 and the cellular inhibitor of apoptosis ciap1, the latter being essential for nf-κb activation. |
2015-01-21 |
2023-08-12 |
Not clear |
Marjan M Tajrishi, Timothy S Zheng, Linda C Burkly, Ashok Kuma. The TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and disease. Cytokine & growth factor reviews. vol 25. issue 2. 2015-01-10. PMID:24444596. |
tnf-like weak inducer of apoptosis (tweak), a tnf superfamily ligand, and its bona fide receptor, the tnf receptor superfamily member fibroblast growth factor-inducible 14 (fn14), represent a pivotal axis for shaping both physiological and pathological tissue responses to acute or chronic injury and disease. |
2015-01-10 |
2023-08-12 |
Not clear |
Yuko Katao, Mika Shishido, Kaoru Inami, Naoyuki Matsumoto, Hirofumi Sawa. An inhibitory role for caspase-3 at the late stage of RANKL-induced osteoclast differentiation in RAW264 cells and mouse bone marrow macrophages. Cell biology international. vol 38. issue 6. 2015-01-10. PMID:24523219. |
several members of the tnf family, such as tnf and fas ligand, can induce apoptosis by activation of caspase-3. |
2015-01-10 |
2023-08-12 |
mouse |
Zhilin Qi, Lei Shen, Huiting Zhou, Yi Jiang, Lei Lan, Lan Luo, Zhimin Yi. Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling. Cellular signalling. vol 26. issue 7. 2015-01-10. PMID:24686082. |
tumor necrosis factor (tnf)-α is a potent cytokine that regulates critical cellular processes including apoptosis. |
2015-01-10 |
2023-08-12 |
human |
Sahdeo Prasad, Ji Hye Kim, Subash C Gupta, Bharat B Aggarwa. Targeting death receptors for TRAIL by agents designed by Mother Nature. Trends in pharmacological sciences. vol 35. issue 10. 2015-01-10. PMID:25128958. |
these nutraceuticals increase tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis of cancer cells through different mechanisms. |
2015-01-10 |
2023-08-13 |
Not clear |
Hamid Reza Heidari, Mojgan Bandehpour, Hossein Vahidi, Jaleh Barar, Bahram Kazemi, Hossein Naderi-Manes. Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 1. 2015-01-06. PMID:25561925. |
cloning and expression of tnf related apoptosis inducing ligand in nicotiana tabacum. |
2015-01-06 |
2023-08-13 |
human |
Hamid Reza Heidari, Mojgan Bandehpour, Hossein Vahidi, Jaleh Barar, Bahram Kazemi, Hossein Naderi-Manes. Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 1. 2015-01-06. PMID:25561925. |
human tnf related apoptosis inducing ligand (trail) as a promising biopharmaceutical candidate has been produced in different expression hosts. |
2015-01-06 |
2023-08-13 |
human |
Uma S Gautam, Smriti Mehra, Muhammad H Ahsan, Xavier Alvarez, Tianhua Niu, Deepak Kausha. Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages. PloS one. vol 9. issue 4. 2014-12-30. PMID:24743303. |
these interactions result in the induction of the tnf signaling pathway, activation of apoptosis, and dna-damage stress response. |
2014-12-30 |
2023-08-13 |
monkey |