| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Lemke, S von Karstedt, J Zinngrebe, H Walcza. Getting TRAIL back on track for cancer therapy. Cell death and differentiation. vol 21. issue 9. 2015-04-22. PMID:24948009. |
unlike other members of the tnf superfamily, the tnf-related apoptosis-inducing ligand (trail, also known as apo2l) possesses the unique capacity to induce apoptosis selectively in cancer cells in vitro and in vivo. |
2015-04-22 |
2023-08-13 |
Not clear |
| Yi Miao, Xue-Yuan Bi, Mei Zhao, Hong-Ke Jiang, Jin-Jun Liu, Dong-Ling Li, Xiao-Jiang Yu, Yong-Hua Yang, Ning Huang, Wei-Jin Zan. Acetylcholine inhibits tumor necrosis factor α activated endoplasmic reticulum apoptotic pathway via EGFR-PI3K signaling in cardiomyocytes. Journal of cellular physiology. vol 230. issue 4. 2015-04-22. PMID:25201632. |
however, whether and how ach affects tnf α-induced endoplasmic reticulum (er) stress and cell apoptosis remain poorly defined. |
2015-04-22 |
2023-08-13 |
Not clear |
| Omid Tavallaei, Mojgan Bandehpour, Nastaran Nafissi-Varcheh, Bahram Kazem. Periplasmic Expression of TNF Related Apoptosis Inducing Ligand (TRAIL) in E.coli. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 2. 2015-04-22. PMID:25901171. |
periplasmic expression of tnf related apoptosis inducing ligand (trail) in e.coli. |
2015-04-22 |
2023-08-13 |
Not clear |
| Omid Tavallaei, Mojgan Bandehpour, Nastaran Nafissi-Varcheh, Bahram Kazem. Periplasmic Expression of TNF Related Apoptosis Inducing Ligand (TRAIL) in E.coli. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 2. 2015-04-22. PMID:25901171. |
tumor necrosis factor-related apoptosis-inducing ligand (trail), a member of tnf family, is an interesting ligand which selectively induces apoptosis in tumor cells and, therefore, it has been developed for cancer therapy. |
2015-04-22 |
2023-08-13 |
Not clear |
| Yves Dondelinger, Wim Declercq, Sylvie Montessuit, Ria Roelandt, Amanda Goncalves, Inge Bruggeman, Paco Hulpiau, Kathrin Weber, Clark A Sehon, Robert W Marquis, John Bertin, Peter J Gough, Savvas Savvides, Jean-Claude Martinou, Mathieu J M Bertrand, Peter Vandenabeel. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. Cell reports. vol 7. issue 4. 2015-04-20. PMID:24813885. |
accordingly, we found that inhibiting the formation of pi(5)p and pi(4,5)p2 specifically inhibits tumor necrosis factor (tnf)-mediated necroptosis but not apoptosis. |
2015-04-20 |
2023-08-13 |
Not clear |
| Rachana Trivedi, Durga Prasad Mishr. Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells. Frontiers in oncology. vol 5. 2015-04-17. PMID:25883904. |
the tumor necrosis factor-related apoptosis-inducing ligand (trail) is a member of the tumor necrosis factor (tnf) family of ligands, which initiates apoptosis in cancer cells through interaction with the death receptors dr4 and dr5. |
2015-04-17 |
2023-08-13 |
Not clear |
| Mengmeng Li, Tao Chen, Zaipei Guo, Jingyi Li, Na Ca. Tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 are expressed in urticarial vasculitis. The Journal of dermatology. vol 40. issue 11. 2015-04-13. PMID:23968277. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak), a member of the tnf family, has been implicated as a pro-inflammatory cytokine in many types of autoimmune and infectious diseases. |
2015-04-13 |
2023-08-12 |
Not clear |
| Jun-Hua Fan, Guo-Gang Feng, Lei Huang, Guo-Duo Tang, Hai-Xing Jiang, Jing X. Naofen promotes TNF-α-mediated apoptosis of hepatocytes by activating caspase-3 in lipopolysaccharide-treated rats. World journal of gastroenterology. vol 20. issue 17. 2015-04-09. PMID:24803807. |
to investigate whether naofen is involved in tumor necrosis factor (tnf)-α-mediated apoptosis of hepatocytes induced by lipopolysaccharide (lps). |
2015-04-09 |
2023-08-13 |
rat |
| Xiaodong Zhang, Yingjie Zhu, Xiantao Chen, Yun Zhang, Ying Zhang, Yudong Jia, Huichao Wang, Youwen Liu, Lianbo Xia. Baicalein ameliorates inflammatory-related apoptotic and catabolic phenotypes in human chondrocytes. International immunopharmacology. vol 21. issue 2. 2015-04-09. PMID:24859058. |
in oa, pro-inflammatory cytokines such as interleukin (il)-1β and tumor necrosis factor (tnf)-α can trigger the caspase cascade to promote apoptosis and activate nf-κb to induce catabolic factors in chondrocytes. |
2015-04-09 |
2023-08-13 |
mouse |
| Gamze Karaca, Guanhua Xie, Cynthia Moylan, Marzena Swiderska-Syn, Cynthia D Guy, Leandi Krüger, Mariana Verdelho Machado, Steve S Choi, Gregory A Michelotti, Linda C Burkly, Anna Mae Dieh. Role of Fn14 in acute alcoholic steatohepatitis in mice. American journal of physiology. Gastrointestinal and liver physiology. vol 308. issue 4. 2015-04-09. PMID:25524063. |
tnf-like weak inducer of apoptosis (tweak) is a growth factor for bipotent liver progenitors that express its receptor, fibroblast growth factor-inducible 14 (fn14), a tnf receptor superfamily member. |
2015-04-09 |
2023-08-13 |
mouse |
| Hitoshi Ueno, Hitomi Kajihara, Hajime Nakamura, Tomofumi Okuno, Fumitoshi Sakazaki, Tomohiro Arakawa, Hirofumi Ogino, Katsuhiko Nakamuro, Junji Yodo. Effect of selenite on T-cell mitogenesis: contribution of ROS production and apoptosis signal-regulating kinase 1. Biological & pharmaceutical bulletin. vol 37. issue 8. 2015-04-06. PMID:25087957. |
this study was conducted to evaluate the relationships between the induction of apoptosis, formation of tumor necrosis factor (tnf)-alpha and reactive oxygen species (ros), activation of apoptosis signal-regulating kinase (ask) 1 and the thioredoxin (trx) system when mitogenesis was stimulated by selenite. |
2015-04-06 |
2023-08-13 |
mouse |
| Kyung Eun Choi, Chul Ju Hwang, Sun Mi Gu, Mi Hee Park, Joo Hwan Kim, Joo Ho Park, Young Jin Ahn, Ji Young Kim, Min Jong Song, Ho Sueb Song, Sang-Bae Han, Jin Tae Hon. Cancer cell growth inhibitory effect of bee venom via increase of death receptor 3 expression and inactivation of NF-kappa B in NSCLC cells. Toxins. vol 6. issue 8. 2015-03-31. PMID:25068924. |
a combination treatment of tumor necrosis factor (tnf)-like weak inducer of apoptosis, tnf-related apoptosis-inducing ligand, docetaxel and cisplatin, with bv synergistically inhibited both a549 and nci-h460 lung cancer cell growth with further down regulation of nf-κb activity. |
2015-03-31 |
2023-08-13 |
bee |
| Ainhoa Pérez-Garijo, Yaron Fuchs, Hermann Stelle. Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway. eLife. vol 2. 2015-03-30. PMID:24066226. |
apoptotic cells can induce non-autonomous apoptosis through the tnf pathway. |
2015-03-30 |
2023-08-12 |
mouse |
| Ainhoa Pérez-Garijo, Yaron Fuchs, Hermann Stelle. Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway. eLife. vol 2. 2015-03-30. PMID:24066226. |
we identified eiger, the drosophila tumor necrosis factor (tnf) homolog, as the signal responsible for apoptosis-induced apoptosis (aia). |
2015-03-30 |
2023-08-12 |
mouse |
| Ewa Jabłońska, Lucja Dakowicz, Wioletta Ratajczak-Wrona, Marzena Garley, Jolanta Sawicka-Powierza, Maryna Krawczuk-Ryba. TNF superfamily proteins in the serum of patients with B-ALL--preliminary study. Clinical laboratory. vol 60. issue 10. 2015-03-11. PMID:25651723. |
tnf superfamily ligands such as b cell-activating factor (baff), a proliferation inducing ligand (april) and tnf-related apoptosis inducing ligand (trail), can play an important role in the pathogenesis and development of various b cell malignancies involving b-all. |
2015-03-11 |
2023-08-13 |
Not clear |
| Marco de Bruyn, Valerie R Wiersma, Wijnand Helfrich, Paul Eggleton, Edwin Breme. The ever-expanding immunomodulatory role of calreticulin in cancer immunity. Frontiers in oncology. vol 5. 2015-03-09. PMID:25750898. |
interestingly, treatment with tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) also induces membrane calreticulin exposure on cancer cells. |
2015-03-09 |
2023-08-13 |
Not clear |
| Pierre-François Cartron, Elise Petit, Grégory Bellot, Lisa Oliver, François M Vallett. Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis. Cellular signalling. vol 26. issue 9. 2015-03-03. PMID:24794530. |
metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for bak activation during tnf alpha triggered apoptosis. |
2015-03-03 |
2023-08-13 |
Not clear |
| Dongxiao Dong, Jing Gao, Ying Sun, Yuqing Long, Meng Li, Dongchao Zhang, Jianfang Gong, Liang Xu, Liuan Li, Shunyi Qin, Jifei Ma, Tianming Ji. Adenovirus-mediated co-expression of the TRAIL and HN genes inhibits growth and induces apoptosis in Marek's disease tumor cell line MSB-1. Cancer cell international. vol 15. 2015-03-02. PMID:25729329. |
the objective of this study was to determine the in vitro tumor-inhibitory effect of a recombinant adenovirus expressing a fusion protein of tumor necrosis factor (tnf) related apoptosis inducing ligand (trail) and hemagglutinin-neuraminidase (hn) genes on the msb-1 marek's disease tumor cell line. |
2015-03-02 |
2023-08-13 |
Not clear |
| Jackeline Agorreta, Jianting Hu, Dongxia Liu, Domenico Delia, Helen Turley, David J P Ferguson, Francisco Iborra, María J Pajares, Marta Larrayoz, Isabel Zudaire, Ruben Pio, Luis M Montuenga, Adrian L Harris, Kevin Gatter, Francesco Pezzell. TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Molecular cancer research : MCR. vol 12. issue 5. 2015-02-27. PMID:24567527. |
the tnf receptor-associated protein 1 (trap1) is a mitochondrial hsp that has been related to drug resistance and protection from apoptosis in colorectal and prostate cancer. |
2015-02-27 |
2023-08-12 |
Not clear |
| Sung-Min Hwang, MeiHong Jin, Yong Hwan Shin, Seul Ki Choi, Eun Namkoong, MinKyoung Kim, Moon-Yong Park, Kyungpyo Par. Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells. Experimental & molecular medicine. vol 46. 2015-02-20. PMID:25502757. |
in addition, based on data suggesting that tumor necrosis factor (tnf)-α induces cell apoptosis, lpa upregulates tnf-induced caspase-3 and cleaved poly(adp-ribose)polymerase (parp). |
2015-02-20 |
2023-08-13 |
Not clear |