| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luisa Costa, Francesco Caso, Mariangela Atteno, Antonio Del Puente, Md Abud Darda, Paolo Caso, Augusta Ortolan, Ugo Fiocco, Roberta Ramonda, Leonardo Punzi, Raffaele Scarp. Impact of 24-month treatment with etanercept, adalimumab, or methotrexate on metabolic syndrome components in a cohort of 210 psoriatic arthritis patients. Clinical rheumatology. vol 33. issue 6. 2015-02-13. PMID:23959447. |
tumor necrosis factor (tnf)-α is a pro-inflammatory adipocytokine mainly produced by monocytes and macrophages with a central role in inflammatory responses, but it also induces adipocytes apoptosis, promotes insulin resistance, and stimulates lipolysis. |
2015-02-13 |
2023-08-12 |
Not clear |
| Ji-Hyun Park, Woo-Ram Lee, Hyun-Soo Kim, Sang-Mi Han, Young-Chae Chang, Kwan-Kyu Par. Protective effects of melittin on tumor necrosis factor-α induced hepatic damage through suppression of apoptotic pathway and nuclear factor-kappa B activation. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 12. 2015-02-10. PMID:24872433. |
in the present study, we investigated the anti-apoptotic effect of melittin on tumor necrosis factor (tnf)-α/actinomycin (act) d-induced apoptosis in hepatocytes. |
2015-02-10 |
2023-08-13 |
bee |
| Eiji Kobayashi, Hiroyuki Kishi, Tatsuhiko Ozawa, Hiroshi Hamana, Hidetoshi Nakagawa, Aishun Jin, Zhezhu Lin, Atsushi Muraguch. A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells. Biochemical and biophysical research communications. vol 453. issue 4. 2015-02-09. PMID:25445592. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and its associated receptors (trail-r/tr) are attractive targets for cancer therapy because trail induces apoptosis in tumor cells through tr while having little cytotoxicity on normal cells. |
2015-02-09 |
2023-08-13 |
human |
| Jiřina Hofmanová, Nicol Straková, Alena Hyršlová Vaculová, Zuzana Tylichová, Barbora Safaříková, Belma Skender, Alois Kozubí. Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer. Mediators of inflammation. vol 2014. 2015-02-07. PMID:24876678. |
cytokines from the tnf family (tnf- α, trail, and fasl) have potent inflammatory activities and can also regulate apoptosis, which plays an important role in cancer development. |
2015-02-07 |
2023-08-13 |
Not clear |
| Jiřina Hofmanová, Nicol Straková, Alena Hyršlová Vaculová, Zuzana Tylichová, Barbora Safaříková, Belma Skender, Alois Kozubí. Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer. Mediators of inflammation. vol 2014. 2015-02-07. PMID:24876678. |
the results of our own research showed enhancement of apoptosis in colon cancer cells by a combination of either docosahexaenoic acid (dha) or butyrate with tnf family cytokines, especially by promotion of the mitochondrial apoptotic pathway and modulation of nf κ b activity. |
2015-02-07 |
2023-08-13 |
Not clear |
| Musarat Ishaq, Shailesh Kumar, Hilal Varinli, Zhao Jun Han, Amanda E Rider, Margaret D M Evans, Anthony B Murphy, Kostya Ostriko. Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Molecular biology of the cell. vol 25. issue 9. 2015-02-02. PMID:24574456. |
by screening genes involved in apoptosis, we identify tumor necrosis factor (tnf)-family members as the most differentially expressed cellular genes upon agp treatment of melanoma cells. |
2015-02-02 |
2023-08-12 |
Not clear |
| Musarat Ishaq, Shailesh Kumar, Hilal Varinli, Zhao Jun Han, Amanda E Rider, Margaret D M Evans, Anthony B Murphy, Kostya Ostriko. Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Molecular biology of the cell. vol 25. issue 9. 2015-02-02. PMID:24574456. |
tnf receptor 1 (tnfr1) antagonist-neutralizing antibody specifically inhibits agp-induced apoptosis signal, regulating apoptosis signal-regulating kinase 1 (ask1) activity and subsequent ask1-dependent apoptosis. |
2015-02-02 |
2023-08-12 |
Not clear |
| A Marivin, J Berthelet, J Cartier, C Paul, S Gemble, A Morizot, W Boireau, M Saleh, J Bertoglio, E Solary, L Dubre. cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation. Oncogene. vol 33. issue 48. 2015-01-21. PMID:24276241. |
tnf receptor engagement induces the formation of a multimolecular complex including the tnfr-associated factor traf2, the receptor-interaction protein kinase rip1 and the cellular inhibitor of apoptosis ciap1, the latter being essential for nf-κb activation. |
2015-01-21 |
2023-08-12 |
Not clear |
| Marjan M Tajrishi, Timothy S Zheng, Linda C Burkly, Ashok Kuma. The TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and disease. Cytokine & growth factor reviews. vol 25. issue 2. 2015-01-10. PMID:24444596. |
tnf-like weak inducer of apoptosis (tweak), a tnf superfamily ligand, and its bona fide receptor, the tnf receptor superfamily member fibroblast growth factor-inducible 14 (fn14), represent a pivotal axis for shaping both physiological and pathological tissue responses to acute or chronic injury and disease. |
2015-01-10 |
2023-08-12 |
Not clear |
| Yuko Katao, Mika Shishido, Kaoru Inami, Naoyuki Matsumoto, Hirofumi Sawa. An inhibitory role for caspase-3 at the late stage of RANKL-induced osteoclast differentiation in RAW264 cells and mouse bone marrow macrophages. Cell biology international. vol 38. issue 6. 2015-01-10. PMID:24523219. |
several members of the tnf family, such as tnf and fas ligand, can induce apoptosis by activation of caspase-3. |
2015-01-10 |
2023-08-12 |
mouse |
| Zhilin Qi, Lei Shen, Huiting Zhou, Yi Jiang, Lei Lan, Lan Luo, Zhimin Yi. Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling. Cellular signalling. vol 26. issue 7. 2015-01-10. PMID:24686082. |
tumor necrosis factor (tnf)-α is a potent cytokine that regulates critical cellular processes including apoptosis. |
2015-01-10 |
2023-08-12 |
human |
| Sahdeo Prasad, Ji Hye Kim, Subash C Gupta, Bharat B Aggarwa. Targeting death receptors for TRAIL by agents designed by Mother Nature. Trends in pharmacological sciences. vol 35. issue 10. 2015-01-10. PMID:25128958. |
these nutraceuticals increase tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis of cancer cells through different mechanisms. |
2015-01-10 |
2023-08-13 |
Not clear |
| Hamid Reza Heidari, Mojgan Bandehpour, Hossein Vahidi, Jaleh Barar, Bahram Kazemi, Hossein Naderi-Manes. Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 1. 2015-01-06. PMID:25561925. |
cloning and expression of tnf related apoptosis inducing ligand in nicotiana tabacum. |
2015-01-06 |
2023-08-13 |
human |
| Hamid Reza Heidari, Mojgan Bandehpour, Hossein Vahidi, Jaleh Barar, Bahram Kazemi, Hossein Naderi-Manes. Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 1. 2015-01-06. PMID:25561925. |
human tnf related apoptosis inducing ligand (trail) as a promising biopharmaceutical candidate has been produced in different expression hosts. |
2015-01-06 |
2023-08-13 |
human |
| Uma S Gautam, Smriti Mehra, Muhammad H Ahsan, Xavier Alvarez, Tianhua Niu, Deepak Kausha. Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages. PloS one. vol 9. issue 4. 2014-12-30. PMID:24743303. |
these interactions result in the induction of the tnf signaling pathway, activation of apoptosis, and dna-damage stress response. |
2014-12-30 |
2023-08-13 |
monkey |
| Linda C Burkl. TWEAK/Fn14 axis: the current paradigm of tissue injury-inducible function in the midst of complexities. Seminars in immunology. vol 26. issue 3. 2014-12-22. PMID:24636536. |
tnf-like weak inducer of apoptosis (tweak), a tnf family ligand, and its only known signaling receptor, fgf-inducible molecule-14 (fn14), have emerged as a key molecular pathway regulating tissue responses after acute tissue injury and in contexts of chronic injury and disease, including autoimmunity, chronic inflammation, fibrosis, and malignancy. |
2014-12-22 |
2023-08-12 |
Not clear |
| Guoxin Ren, Jingzhou Hu, Runxiang Wang, Wei Han, Mei Zhao, Ge Zhou, Chenping Zhang, Zhiyuan Zhan. Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma. Oncology reports. vol 31. issue 6. 2014-12-17. PMID:24737049. |
the results indicated that lps significantly stimulated hnscc cell proliferation, cytokine production, migration, invasion and resistance to apoptosis induced by tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail). |
2014-12-17 |
2023-08-13 |
Not clear |
| Sol Ji Park, Bumrae Cho, Ok Jae Koo, Hwajung Kim, Jung Taek Kang, Sunghoon Hurh, Su Jin Kim, Hye Jung Yeom, Joonho Moon, Eun Mi Lee, Ji Yei Choi, Ju Ho Hong, Goo Jang, Joing-Ik Hwang, Jaeseok Yang, Byeong Chun Lee, Curie Ah. Production and characterization of soluble human TNFRI-Fc and human HO-1(HMOX1) transgenic pigs by using the F2A peptide. Transgenic research. vol 23. issue 3. 2014-12-16. PMID:24497084. |
soluble human tnfri-fc (shtnfri-fc) can inhibit the binding of human tnf-α (htnf-α) to tnf receptors on porcine cells, and thereby, prevent htnf-α-mediated inflammation and apoptosis. |
2014-12-16 |
2023-08-12 |
human |
| Makoto Edagawa, Junya Kawauchi, Manabu Hirata, Hiroto Goshima, Makoto Inoue, Tatsuro Okamoto, Akira Murakami, Yoshihiko Maehara, Shigetaka Kitajim. Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib. The Journal of biological chemistry. vol 289. issue 31. 2014-12-15. PMID:24939851. |
role of activating transcription factor 3 (atf3) in endoplasmic reticulum (er) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-mediated apoptosis through up-regulation of death receptor 5 (dr5) by zerumbone and celecoxib. |
2014-12-15 |
2023-08-13 |
human |
| Stephen Lee Rego, Muthulekha Swamydas, Amritha Kidiyoor, Rachel Helms, Alexander De Piante, Amanda L Lance, Pinku Mukherjee, Didier Dréa. Soluble tumor necrosis factor receptors shed by breast tumor cells inhibit macrophage chemotaxis. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 33. issue 11. 2014-12-05. PMID:23777205. |
through tnf-α converting enzyme (tace/adam17) activities, breast tumor cells shed membrane-bound proteins, including their tnf receptors (stnfr1/2), which serve as decoys sequestering tnf-α and preventing tnf-α-driven apoptosis of tumor cells, thereby decreasing tnf-α bioavailability. |
2014-12-05 |
2023-08-12 |
Not clear |