| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anuja Chattopadhyay, Irina Abecassis, Robert L Redne. NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK. Leukemia & lymphoma. vol 56. issue 12. 2016-09-20. PMID:25791120. |
we propose that inhibition of tnf activation of apoptosis, while preserving tnf activation of nfκb and jnk pathways that stimulate cell growth and survival, represents a novel mechanism through which npm-rar contributes to development of the leukemic phenotype. |
2016-09-20 |
2023-08-13 |
Not clear |
| Özlem Bilgiç, Abdullah Sivrikaya, Aysun Toker, Ali Ünlü, Cevdet Altınyaza. Serum levels of TWEAK in patients with psoriasis vulgaris. Cytokine. vol 77. 2016-09-14. PMID:26499979. |
tumour necrosis factor (tnf)-like weak inducer of apoptosis (tweak) has been implicated in the pathogenesis of a variety of inflammatory disorders and autoimmune diseases. |
2016-09-14 |
2023-08-13 |
human |
| Crina Claudia Rusu, Simona Racasan, Ina Maria Kacso, Liviu Ghervan, Diana Moldovan, Alina Potra, Ioan Mihai Patiu, Cosmina Bondor, Mirela Gherman Caprioar. The association of high sCD163/sTWEAK ratio with cardiovascular disease in hemodialysis patients. International urology and nephrology. vol 47. issue 12. 2016-09-13. PMID:26433887. |
transmembrane proteins that circulate as soluble form such as tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) and cd163 have been proposed in previous studies as cvd biomarkers in chronic kidney disease patients. |
2016-09-13 |
2023-08-13 |
Not clear |
| Rodrigo Antônio Mattei, Eduardo Monguilhott Dalmarco, Tânia Silvia Fröd. Etanercept administration prevents the inflammatory response induced by carrageenan in the murine air pouch model. Naunyn-Schmiedeberg's archives of pharmacology. vol 388. issue 12. 2016-09-12. PMID:26255064. |
exudation; leukocytes; myeloperoxidase (mpo); adenosine deaminase (ada); nitric oxide metabolites (nox); tumor necrosis factor (tnf); interferon gamma (ifn-γ); interleukins (il) il-6, il-17, il-10, il-4, and il-2; nuclear transcription factor kappa b (nf-κb) activation and apoptosis were evaluated 24 h after the induction of inflammation. |
2016-09-12 |
2023-08-13 |
mouse |
| Sahar Elhannan, Safa Taha, Noureddine Ben Khalaf, Halla Bakheit, M Dahmani Fathallah, Moiz Bakhie. Induction of dissociated cytokine profiles by ISRAA with selective critical involvement of ERK1/2 in its signaling functions. International journal of molecular medicine. vol 36. issue 6. 2016-09-12. PMID:26499109. |
we have previously demonstrated that israa and tumor necrosis factor (tnf) receptor 1 (tnfr1) share an interspecies-conserved motif (72% homology) that induces the apoptosis and proliferation of human peripheral blood mononuclear cells (hpbmcs) in a dose-dependent manner. |
2016-09-12 |
2023-08-13 |
human |
| N Preyat, M Rossi, J Kers, L Chen, J Bertin, P J Gough, A Le Moine, A Rongvaux, F Van Gool, O Le. Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner. Cell death and differentiation. vol 23. issue 1. 2016-09-09. PMID:26001219. |
of interest, most ligands known to induce necroptosis (including notably tnf and fasl) can also promote apoptosis, and the mechanisms regulating the decision of cells to commit to one form of cell death or the other are still poorly defined. |
2016-09-09 |
2023-08-13 |
Not clear |
| Veronica Tisato, Arianna Gonelli, Rebecca Voltan, Paola Secchiero, Giorgio Zaul. Clinical perspectives of TRAIL: insights into central nervous system disorders. Cellular and molecular life sciences : CMLS. vol 73. issue 10. 2016-09-07. PMID:26910728. |
the tnf-related apoptosis inducing ligand trail is a member of the tnf superfamily that has been firstly studied and evaluated for its anti-cancer activity, and the insights into its biology have already led to the identification of several trail-based anticancer strategies with strong clinical therapeutic potentials. |
2016-09-07 |
2023-08-13 |
Not clear |
| Stéphanie Plenchette, Sabrina Romagny, Véronique Laurens, Ali Bettaie. S-Nitrosylation in TNF superfamily signaling pathway: Implication in cancer. Redox biology. vol 6. 2016-09-05. PMID:26448396. |
in this review, we summarize several examples of protein modification by s-nitrosylation that regulate signaling pathways engaged by members of the tnf superfamily (fas ligand (fasl), tumor-necrosis-factor-related apoptosis inducing ligand (trail) and tnfalpha (tnfα)) and the way it influences cell fate decisions. |
2016-09-05 |
2023-08-13 |
Not clear |
| Mi Hee Park, Jong Han Kim, Young-Ho Chung, Seung Ho Le. Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins. Biochemical and biophysical research communications. vol 473. issue 2. 2016-08-29. PMID:27033605. |
we investigated whether bakuchiol, an analog of resveratrol enhances the apoptosis ability of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) in cancer cells. |
2016-08-29 |
2023-08-13 |
Not clear |
| Leeyah Issop, Mariano A Ostuni, Sunghoon Lee, Mireille Laforge, Gabriel Péranzi, Pierre Rustin, Jean-François Benoist, Jérome Estaquier, Vassilios Papadopoulos, Jean-Jacques Lacapèr. Translocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic Cells. PloS one. vol 11. issue 4. 2016-08-29. PMID:27054921. |
tnf also destabilized mitochondrial ultrastructure, inducing cell death by apoptosis. |
2016-08-29 |
2023-08-13 |
human |
| Gustavo P Amarante-Mendes, Thomas S Griffit. Therapeutic applications of TRAIL receptor agonists in cancer and beyond. Pharmacology & therapeutics. vol 155. 2016-08-18. PMID:26343199. |
similar to tnf and fas ligand, trail induces apoptosis in caspase-dependent manner following trail death receptor trimerization. |
2016-08-18 |
2023-08-13 |
Not clear |
| Timothy J Green, Jean-Luc Rolland, Agnes Vergnes, David Raftos, Caroline Montagnan. OsHV-1 countermeasures to the Pacific oyster's anti-viral response. Fish & shellfish immunology. vol 47. issue 1. 2016-08-10. PMID:26384844. |
comparison of apoptosis-related genes revealed that components of the extrinsic apoptosis pathway (tnf) were induced in response to oshv-1 infection, but we failed to observe evidence of apoptosis using a combination of biochemical and molecular assays. |
2016-08-10 |
2023-08-13 |
Not clear |
| Retraction Note to: TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. Molecular and cellular biochemistry. vol 415. issue 1-2. 2016-08-10. PMID:26992906. |
retraction note to: tnf receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. |
2016-08-10 |
2023-08-13 |
Not clear |
| Michael Reiter, Ines Eckhardt, Axel Haferkamp, Simone Fuld. Smac mimetic sensitizes renal cell carcinoma cells to interferon-α-induced apoptosis. Cancer letters. vol 375. issue 1. 2016-08-08. PMID:26912071. |
molecular studies revealed that bv6/ifnα co-treatment triggers apoptosis independently of autocrine/paracrine tumor necrosis factor (tnf)α signaling, since the tnfα-blocking antibody enbrel fails to rescue cell death. |
2016-08-08 |
2023-08-13 |
Not clear |
| Alfonso R Sanchez-Paulete, Sara Labiano, Maria E Rodriguez-Ruiz, Arantza Azpilikueta, Iñaki Etxeberria, Elixabet Bolaños, Valérie Lang, Manuel Rodriguez, M Angela Aznar, Maria Jure-Kunkel, Ignacio Meler. Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy. European journal of immunology. vol 46. issue 3. 2016-08-04. PMID:26773716. |
on t and nk cells, cd137 is expressed following activation and, if ligated by its natural ligand (cd137l), conveys polyubiquitination-mediated signals via tnf receptor associated factor 2 that inhibit apoptosis, while enhancing proliferation and effector functions. |
2016-08-04 |
2023-08-13 |
mouse |
| Jesus Delgado-Calle, Judith Anderson, Meloney D Cregor, Masahiro Hiasa, John M Chirgwin, Nadia Carlesso, Toshiyuki Yoneda, Khalid S Mohammad, Lilian I Plotkin, G David Roodman, Teresita Bellid. Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma. Cancer research. vol 76. issue 5. 2016-07-29. PMID:26833121. |
mechanistic studies revealed that osteocyte apoptosis was initiated by multiple myeloma cell-mediated activation of notch signaling and was further amplified by multiple myeloma cell-secreted tnf. |
2016-07-29 |
2023-08-13 |
mouse |
| Yi Ma, Shaojun Zhao, Shutao Shen, Shixiong Fang, Zulu Ye, Zhi Shi, An Hon. A novel recombinant slow-release TNF α-derived peptide effectively inhibits tumor growth and angiogensis. Scientific reports. vol 5. 2016-07-26. PMID:26337231. |
rmp16 can more effectively induce apoptosis and inhibit proliferation for du145 cells than p16 and tnf α via the caspase-dependent apoptosis pathway and g0/g1 cell cycle arrest. |
2016-07-26 |
2023-08-13 |
mouse |
| Minami Kumazaki, Haruka Shinohara, Kohei Taniguchi, Hiroshi Ueda, Mayuko Nishi, Akihide Ryo, Yukihiro Aka. Understanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by α-mangostin, a xanthone derivative. Oncotarget. vol 6. issue 28. 2016-07-25. PMID:26304927. |
tumor necrosis-factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf-superfamily that selectively induces apoptosis through death receptors (drs) 4 and/or 5 in cancer cells. |
2016-07-25 |
2023-08-13 |
human |
| Eleonora Dondossola, Andrey S Dobroff, Serena Marchiò, Marina Cardó-Vila, Hitomi Hosoya, Steven K Libutti, Angelo Corti, Richard L Sidman, Wadih Arap, Renata Pasqualin. Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 8. 2016-07-25. PMID:26858439. |
we show that these malignant cells home to tumors, locally release tnf, damage neovascular endothelium, and induce massive cancer cell apoptosis. |
2016-07-25 |
2023-08-13 |
mouse |
| W Malorni, R Rivabene, M T Santini, G Rainaldi, G Donell. N-acetylcysteine prevents TNF-induced mitochondrial damage, apoptosis and viral particle production in HIV-infected U937 cells. Redox report : communications in free radical research. vol 1. issue 1. 2016-07-16. PMID:27414179. |
in the present work, we demonstrate (a) that apoptosis can be easily induced by tnf only in infected u937 cells and not in control wild-type cells, (b) that daily treatment of tnf-exposed cells with low concentrations of nac is able to impair viral progeny formation as early as 24 h, (c) that the mitochondrial damage induced by tnf is counteracted by preexposure to nac, and (d) that nac alone exerts changes in mitochondria which may be responsible for the protective effects exerted by this compound. |
2016-07-16 |
2023-08-13 |
human |