| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue Teng, Yuzhuo Wang, Xianglilan Zhang, Wenli Liu, Hang Fan, Hongwu Yao, Baihan Lin, Ping Zhu, Wenjun Yuan, Yigang Tong, Wuchun Ca. Systematic Genome-wide Screening and Prediction of microRNAs in EBOV During the 2014 Ebolavirus Outbreak. Scientific reports. vol 5. 2016-06-14. PMID:26011078. |
additionally, the ebolavirus exploits the mirnas to inhibit the nf-kb and tnf factors to evade the host defense mechanisms that limit replication by killing infected cells, or to conversely trigger apoptosis as a mechanism to increase virus spreading. |
2016-06-14 |
2023-08-13 |
Not clear |
| Ramaswamy Sharma, Paul J Williams, Anjana Gupta, Brandon McCluskey, Shylesh Bhaskaran, Steve Muñoz, Babatunde O Oyajob. A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice. Oncotarget. vol 6. issue 25. 2016-06-10. PMID:26009993. |
tnf also activated caspase-3 and downregulated bcl-2, correlating with the enhanced susceptibility of 5tgm1-âf cells to apoptosis. |
2016-06-10 |
2023-08-13 |
mouse |
| Hongxu Yang, Mian Zhang, Xin Wang, Hongyun Zhang, Jing Zhang, Lei Jing, Lifan Liao, Meiqing Wan. TNF Accelerates Death of Mandibular Condyle Chondrocytes in Rats with Biomechanical Stimulation-Induced Temporomandibular Joint Disease. PloS one. vol 10. issue 11. 2016-06-10. PMID:26529096. |
to determine if temporomandibular joint chondrocyte apoptosis is induced in rats with dental biomechanical stimulation and what a role tnf takes. |
2016-06-10 |
2023-08-13 |
rat |
| Flavia Calmon-Hamaty, Rachel Audo, Bernard Combe, Jacques Morel, Michael Hahn. Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky? Cytokine. vol 75. issue 2. 2016-06-09. PMID:25481649. |
the tnf family member fas ligand (fasl) was reported to trigger apoptosis in fls of arthritic joints by binding to its receptor fas and therefore suggested as a promising candidate for targeting the hyperplastic synovial tissue. |
2016-06-09 |
2023-08-13 |
Not clear |
| Ji-Yeon Seol, Enrico Mihich, Erica S Berlet. TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP. Cytokine. vol 75. issue 2. 2016-06-09. PMID:26198031. |
tnf apoptosis protection fraction (tapf) prevents apoptosis induced by tnf, but not by fas or trail, via nf-κb-induced increase in cflip. |
2016-06-09 |
2023-08-13 |
human |
| Ji-Yeon Seol, Enrico Mihich, Erica S Berlet. TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP. Cytokine. vol 75. issue 2. 2016-06-09. PMID:26198031. |
incubation of human dermal fibroblasts with tapf (tnf apoptosis protection fraction) protects them from apoptosis induced by the subsequent addition of tnf and cycloheximide (chx). |
2016-06-09 |
2023-08-13 |
human |
| Ji-Yeon Seol, Enrico Mihich, Erica S Berlet. TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP. Cytokine. vol 75. issue 2. 2016-06-09. PMID:26198031. |
tapf does not protect against apoptosis induced by chx in combination with either trail (tnf related apoptosis inducing ligand) or an agonistic fas antibody, or against apoptosis induced by the chemotherapeutic agent doxorubicin. |
2016-06-09 |
2023-08-13 |
human |
| Qian Yao, Juan Du, Jie Lin, Yiming Luo, Yuxiang Wang, Yan Liu, Bo Zhang, Caixia Ren, Congrong Li. Prognostic significance of TRAIL signalling molecules in cervical squamous cell carcinoma. Journal of clinical pathology. vol 69. issue 2. 2016-06-06. PMID:26254281. |
tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf superfamily that preferentially induces apoptosis in cancer cells while exhibiting little or no toxicity in normal cells. |
2016-06-06 |
2023-08-13 |
Not clear |
| Brian H May, Shiqiang Deng, Anthony L Zhang, Chuanjian Lu, Charlie C L Xu. In silico database screening of potential targets and pathways of compounds contained in plants used for psoriasis vulgaris. Archives of dermatological research. vol 307. issue 7. 2016-05-31. PMID:26142738. |
all four tms contained compounds that had regulating effects on apoptosis regulator bax, apoptosis regulator bcl-2, caspase-3, tumor necrosis factor (tnf) or prostaglandin g/h synthase 2 (cox2). |
2016-05-31 |
2023-08-13 |
Not clear |
| Chengliang Zhang, Shouzheng Liu, Jianwei W. Association of the Polymorphism of TRAIL with the Risk and Severity of Lumbar Disc Degeneration in Chinese Han Population. Genetic testing and molecular biomarkers. vol 19. issue 8. 2016-05-23. PMID:26083528. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces apoptosis of various normal and tumor cells. |
2016-05-23 |
2023-08-13 |
Not clear |
| Tomoko Asaoka, Fumiyo Iked. New Insights into the Role of Ubiquitin Networks in the Regulation of Antiapoptosis Pathways. International review of cell and molecular biology. vol 318. 2016-05-20. PMID:26315885. |
we further discuss ubiquitination in the tumor necrosis factor (tnf) signaling pathway as an example for the ubiquitin-dependent regulation of apoptosis and cell survival. |
2016-05-20 |
2023-08-13 |
Not clear |
| Bushra Iqbal, Archna Ghildiyal, Sahabjada, Shraddha Singh, Mohd Arshad, Abbas Ali Mahdi, Sunita Tiwar. Antiproliferative and Apoptotic Effect of Curcumin and TRAIL (TNF Related Apoptosis inducing Ligand) in Chronic Myeloid Leukaemic Cells. Journal of clinical and diagnostic research : JCDR. vol 10. issue 4. 2016-05-18. PMID:27190933. |
antiproliferative and apoptotic effect of curcumin and trail (tnf related apoptosis inducing ligand) in chronic myeloid leukaemic cells. |
2016-05-18 |
2023-08-13 |
Not clear |
| Alaa E El-Sisi, Samia S Sokar, Tarek A Salem, Sally E Abu Rish. PPARγ-dependent anti-tumor and immunomodulatory actions of pioglitazone. Journal of immunotoxicology. vol 12. issue 4. 2016-05-13. PMID:25425470. |
the effects in tumor-bearing hosts of several doses of pio (100 mg/kg, per os), with and without the added presence of dox (2 mg/kg, ip), was investigated in vivo; end-points evaluated included assessment of tumor volume, splenic lymphocyte profiles/functionality, tumor necrosis factor (tnf)-α content, as well as apoptosis and expression of nuclear factor-κb (nf-κb) among the tumor cells. |
2016-05-13 |
2023-08-13 |
mouse |
| Benping Zhang, Feng Li, Weijiang Zhao, Jiebing Li, Qingsong Li, Weizhi Wan. Protective effects of allicin against ischemic stroke in a rat model of middle cerebral artery occlusion. Molecular medicine reports. vol 12. issue 3. 2016-05-12. PMID:26045182. |
neurological score, cerebral infarct size, brain water content, neuronal apoptosis, serum tumor necrosis factor (tnf)‑α and myeloperoxidase (mpo) activity were measured. |
2016-05-12 |
2023-08-13 |
rat |
| Cheng-Chih Hsiao, Kerstin Keysselt, Hsin-Yi Chen, Doreen Sittig, Jörg Hamann, Hsi-Hsien Lin, Gabriela Aus. The Adhesion GPCR CD97/ADGRE5 inhibits apoptosis. The international journal of biochemistry & cell biology. vol 65. 2016-05-12. PMID:26071181. |
stable overexpression of wild-type cd97 reduced serum starvation- and staurosporine-induced intrinsic and tumor necrosis factor (tnf)/cycloheximide-induced extrinsic apoptosis, indicated by an increase in cell viability, a lower percentage of cells within the subg0/g1 phase, expressing annexin v, or having condensed nuclei, and a reduction of dna laddering. |
2016-05-12 |
2023-08-13 |
Not clear |
| S L Petersen, T T Chen, D A Lawrence, S A Marsters, F Gonzalvez, A Ashkenaz. TRAF2 is a biologically important necroptosis suppressor. Cell death and differentiation. vol 22. issue 11. 2016-05-09. PMID:25882049. |
here, we show that tnf receptor-associated factor 2 (traf2)-previously implicated in apoptosis suppression-also inhibits necroptotic signaling by tnfα. |
2016-05-09 |
2023-08-13 |
mouse |
| Barun Mahata, Soumika Biswas, Patricia Rayman, Ali Chahlavi, Jennifer Ko, Ashish Bhattacharjee, Yu-Teh Li, Yuntao Li, Tanya Das, Gaurisankar Sa, Baisakhi Raychaudhuri, Michael A Vogelbaum, Charles Tannenbaum, James H Finke, Kaushik Biswa. GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway. PloS one. vol 10. issue 7. 2016-05-04. PMID:26226135. |
here we show that gbm-derived gangliosides induce apoptosis through involvement of the tnf receptor and activation of the caspase cascade. |
2016-05-04 |
2023-08-13 |
human |
| Barun Mahata, Soumika Biswas, Patricia Rayman, Ali Chahlavi, Jennifer Ko, Ashish Bhattacharjee, Yu-Teh Li, Yuntao Li, Tanya Das, Gaurisankar Sa, Baisakhi Raychaudhuri, Michael A Vogelbaum, Charles Tannenbaum, James H Finke, Kaushik Biswa. GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway. PloS one. vol 10. issue 7. 2016-05-04. PMID:26226135. |
thus, gbm-ganglioside can mediate t cell apoptosis by interacting with the tnf receptor followed by activation of both the extrinsic and the intrinsic pathway of caspases. |
2016-05-04 |
2023-08-13 |
human |
| Sean M Ronnekleiv-Kelly, Manabu Nukaya, Carol J Díaz-Díaz, Bryant W Megna, Patrick R Carney, Peter G Geiger, Gregory D Kenned. Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells. Cancer letters. vol 370. issue 1. 2016-04-27. PMID:26515162. |
we identified that the involvement of up-regulation of pro-apoptotic cytokines tumor necrosis factor (tnf) α and β genes and consequent activation of the tnf-mediated transcriptional pathway in chrysin-induced apoptosis. |
2016-04-27 |
2023-08-13 |
human |
| Rafia S Al-Lamki, Tanya N Mayada. TNF receptors: signaling pathways and contribution to renal dysfunction. Kidney international. vol 87. issue 2. 2016-04-25. PMID:25140911. |
tumor necrosis factor (tnf), initially reported to induce tumor cell apoptosis and cachexia, is now considered a central mediator of a broad range of biological activities from cell proliferation, cell death and differentiation to induction of inflammation and immune modulation. |
2016-04-25 |
2023-08-13 |
Not clear |