| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sung-Chul Lim, Keshab Raj Parajuli, Song Iy Ha. The alkyllysophospholipid edelfosine enhances TRAIL-mediated apoptosis in gastric cancer cells through death receptor 5 and the mitochondrial pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26615420. |
interestingly, low concentrations of edelfosine (5-10 μm) effectively enhanced recombinant human tumor necrosis factor (tnf)-related apoptosis-inducing ligand (rhtrail/tnfsf10)-induced apoptosis and clonogenicity in gastric cancer cells, including trail-resistant ags cells. |
2017-02-06 |
2023-08-13 |
human |
| Prajitha Mohandas Edathara, Manjula Gorre, Sailaja Kagita, Sugunakar Vuree, Anuradha Cingeetham, Santhoshi Rani Nanchari, Phanni Bhushann Meka, Sandhya Annamaneni, Raghunadha Rao Digumarthi, Vishnupriya Satt. Association of promoter polymorphisms of Fas -FasL genes with development of Chronic Myeloid Leukemia. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 4. 2017-02-01. PMID:26563376. |
fas (fas cell surface death receptor) is a member of tumor necrosis factor (tnf) superfamily which interacts with its ligand, fasl, to initiate apoptosis. |
2017-02-01 |
2023-08-13 |
human |
| Se-Hui Kang, In-Hu Hwang, Eunju Son, Chong-Kwan Cho, Jong-Soon Choi, Soo-Jung Park, Byeong-Churl Jang, Kyung-Bok Lee, Zee-Won Lee, Jong Hoon Lee, Hwa-Seung Yoo, Ik-Soon Jan. Allergen-Removed Rhus verniciflua Extract Induces Ovarian Cancer Cell Death via JNK Activation. The American journal of Chinese medicine. vol 44. issue 8. 2017-01-26. PMID:27848251. |
nf-[formula: see text]b antagonizes tumor necrosis factor (tnf)-[formula: see text]-induced apoptosis through a process involving attenuation of the c-jun-n-terminal kinase (jnk). |
2017-01-26 |
2023-08-13 |
Not clear |
| Hae Jeong Park, Su Kang Kim, Hyun-Kyung Park, Joo-Ho Chun. Association of promoter polymorphism -857C/T (rs1799724) in tumor necrosis factor gene with intracerebral hemorrhage in Korean males. Neurological research. vol 39. issue 1. 2017-01-17. PMID:27809686. |
tumor necrosis factor (tnf) has been shown to be involved in the pathogenesis of hemorrhagic stroke, having deleterious effects on cerebral arteries by promoting inflammation and apoptosis in vascular and immune cells. |
2017-01-17 |
2023-08-13 |
Not clear |
| Fang Wang, Xueliang Zhang, Yan Wang, Zhaohui Su. Association of Polymorphisms in TRAIL and Chronic Hepatitis B in Chinese Han Populations from Shandong Province. Annals of clinical and laboratory science. vol 46. issue 4. 2017-01-13. PMID:27466296. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) belongs to the tnf-super family and can induce apoptosis in addition to other biological effects. |
2017-01-13 |
2023-08-13 |
Not clear |
| I I Galkin, O Yu Pletjushkina, R A Zinovkin, V V Zakharova, B V Chernyak, E N Popov. Mitochondria-Targeted Antioxidant SkQR1 Reduces TNF-Induced Endothelial Permeability in vitro. Biochemistry. Biokhimiia. vol 81. issue 10. 2017-01-12. PMID:27908243. |
tnf at high concentrations causes apoptosis of endothelial cells. |
2017-01-12 |
2023-08-13 |
Not clear |
| Hong Cheng, Meifeng Xu, Xiaoming Liu, Xiaoyan Zou, Na Zhan, Yumin Xi. TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation. Experimental dermatology. vol 25. issue 1. 2017-01-10. PMID:26264384. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) has been reported to induce keratinocyte apoptosis in vitro by engaging its sole receptor of fibroblast growth factor-inducible 14 (fn14). |
2017-01-10 |
2023-08-13 |
Not clear |
| Sajad Mir, Farrah Ali, Deepika Chauhan, Rajesh Arora, Haider A Kha. Accumulation of reactivity to MBP sensitizes TRAIL mediated oligodendrocyte apoptosis in adult sub cortical white matter in a model for human multiple sclerosis. Metabolic brain disease. vol 31. issue 2. 2017-01-10. PMID:26477945. |
increased reactivity to mbp was studied to sensitize tnf related apoptosis-inducing ligand (trail) and other proinflammatory cytokines in a cumulative fashion leading to the caspase dependent apoptosis of oligodendrocytes and myelin loss. |
2017-01-10 |
2023-08-13 |
human |
| Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekera, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Gordon K Smyth, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silk. TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. eLife. vol 4. 2017-01-10. PMID:26701909. |
traf2 regulates tnf and nf-κb signalling to suppress apoptosis and skin inflammation independently of sphingosine kinase 1. |
2017-01-10 |
2023-08-13 |
mouse |
| Diego De Miguel, Ana Gallego-Lleyda, José M Ayuso, Aleksandra Pawlak, Blanca Conde, Ignacio Ochoa, Luis J Fernández, Alberto Anel, Luis Martinez-Losta. Improved Anti-Tumor Activity of Novel Highly Bioactive Liposome-Bound TRAIL in Breast Cancer Cells. Recent patents on anti-cancer drug discovery. vol 11. issue 2. 2017-01-09. PMID:26924736. |
apo2-ligand/trail, a member of the tnf cytokine superfamily capable of inducing apoptosis on tumor cells while sparing normal cells, is a promising anti-tumor agent. |
2017-01-09 |
2023-08-13 |
human |
| Katarzyna Ptaszynska-Kopczynska, Marta Marcinkiewicz-Siemion, Anna Lisowska, Ewa Waszkiewicz, Marcin Witkowski, Malgorzata Jasiewicz, Paula Miklasz, Piotr Jakim, Bogdan Galar, Wlodzimierz Jerzy Musial, Karol Adam Kaminsk. Alterations of soluble TWEAK and CD163 concentrations in patients with chronic heart failure. Cytokine. vol 80. 2016-12-29. PMID:26916171. |
a novel mediator from tnf family: soluble tumor necrosis factor-like weak inducer of apoptosis (stweak) along its soluble decoy receptor cd163 (scd163) recently has been investigated in other cardiovascular pathologies. |
2016-12-29 |
2023-08-13 |
human |
| N Yoon, M S Park, T Shigemoto, G Peltier, R H Le. Activated human mesenchymal stem/stromal cells suppress metastatic features of MDA-MB-231 cells by secreting IFN-β. Cell death & disease. vol 7. 2016-12-15. PMID:27077807. |
our recent study showed that human mesenchymal stem/stromal cells (hmscs) are activated to express tumor necrosis factor (tnf)-α-related apoptosis-inducing ligand (trail) by exposure to tnf-α and these activated hmscs effectively induce apoptosis in triple-negative breast cancer mda-mb-231 (mda) cells in vitro and in vivo. |
2016-12-15 |
2023-08-13 |
human |
| Diego De Miguel, Ana Gallego-Lleyda, José María Ayuso, Sandra Erviti-Ardanaz, Roberto Pazo-Cid, Celia del Agua, Luis José Fernández, Ignacio Ochoa, Alberto Anel, Luis Martinez-Losta. TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells. Nanotechnology. vol 27. issue 18. 2016-12-14. PMID:27001952. |
apo2-ligand/trail is a tnf family member able to induce apoptosis in tumor cells but not in normal cells. |
2016-12-14 |
2023-08-13 |
human |
| Zheng Zhenzhong, Yu Yafa, Liang Ji. Fibrinogen-like protein 2 gene silencing inhibits cardiomyocytes apoptosis, improves heart function of streptozotocin-induced diabetes rats and the molecular mechanism involved. Bioscience reports. vol 35. issue 3. 2016-12-13. PMID:26182381. |
we found that fgl2 gene silencing inhibits apoptosis and improves heart function of streptozotocin (stz)-induced diabetes rats, the possible mechanism maybe that fgl2 gene silencing reduces the tumour necrosis factor (tnf)±levels, decreases the expression of b-cell lymphoma-2 (bcl2), bcl-2-associated x (bax), toll-like receptors 4 (tlr4) and p38 mitogen-activated protein kinase (mapk). |
2016-12-13 |
2023-08-13 |
rat |
| Hande Yapislar, Eylem Taskin, Sule Ozdas, Demet Akin, Emine Sonme. Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite. Biological trace element research. vol 170. issue 2. 2016-12-13. PMID:26306587. |
after that, western blotting was performed in order to evaluate protein expression levels of several inflammation markers including il-1β, tumor necrosis factor (tnf)-α, and nuclear factor kappa b (nf-κb), and immunohistochemistry was carried out to detect apoptosis in liver cell culture. |
2016-12-13 |
2023-08-13 |
rat |
| Hande Yapislar, Eylem Taskin, Sule Ozdas, Demet Akin, Emine Sonme. Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite. Biological trace element research. vol 170. issue 2. 2016-12-13. PMID:26306587. |
the present study was pointed out that adr causes hepatotoxicity via apoptosis and/or inflammation processes resulting from initiator nf-κb and tnf which causes proinflammatory mediators such as il-1β. |
2016-12-13 |
2023-08-13 |
rat |
| H Fragoso-Loyo, Y Atisha-Fregoso, C A Nuñez-Alvarez, L Llorent. Utility of TWEAK to assess neuropsychiatric disease activity in systemic lupus erhytematosus. Lupus. vol 25. issue 4. 2016-12-13. PMID:26466614. |
the purpose of this study was to assess the utility of tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) in serum and cerebrospinal fluid (csf) as a biomarker in neuropsychiatric systemic lupus erythematosus (npsle). |
2016-12-13 |
2023-08-13 |
Not clear |
| Larissa M Coutinho, Erica L Vieira, Cynthia Dela Cruz, Maíra Casalechi, Antonio L Teixeira, Helen L Del Puerto, Fernando M Rei. Apoptosis modulation by activin A and follistatin in human endometrial stromal cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 32. issue 2. 2016-12-13. PMID:26494397. |
this study investigated the effects of activin a on total death and apoptosis rates and on tumor necrosis factor (tnf) release by human endometrial stromal cells (hesc). |
2016-12-13 |
2023-08-13 |
human |
| Larissa M Coutinho, Erica L Vieira, Cynthia Dela Cruz, Maíra Casalechi, Antonio L Teixeira, Helen L Del Puerto, Fernando M Rei. Apoptosis modulation by activin A and follistatin in human endometrial stromal cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 32. issue 2. 2016-12-13. PMID:26494397. |
apoptosis and total cell death were measured by flow cytometry, while tnf concentrations in culture media were quantified by elisa. |
2016-12-13 |
2023-08-13 |
human |
| Valvanera Fernández-Laso, Cristina Sastre, Jose M Valdivielso, Angels Betriu, Elvira Fernández, Jesús Egido, Jose L Martín-Ventura, Luis M Blanco-Coli. Soluble TWEAK and Major Adverse Cardiovascular Events in Patients with CKD. Clinical journal of the American Society of Nephrology : CJASN. vol 11. issue 3. 2016-12-13. PMID:26728587. |
soluble tnf-like weak inducer of apoptosis (stweak) is a proinflammatory cytokine belonging to the tnf superfamily. |
2016-12-13 |
2023-08-13 |
Not clear |