| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I I Galkin, O Yu Pletjushkina, R A Zinovkin, V V Zakharova, B V Chernyak, E N Popov. Mitochondria-Targeted Antioxidant SkQR1 Reduces TNF-Induced Endothelial Permeability in vitro. Biochemistry. Biokhimiia. vol 81. issue 10. 2017-01-12. PMID:27908243. |
tnf at high concentrations causes apoptosis of endothelial cells. |
2017-01-12 |
2023-08-13 |
Not clear |
| Hong Cheng, Meifeng Xu, Xiaoming Liu, Xiaoyan Zou, Na Zhan, Yumin Xi. TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation. Experimental dermatology. vol 25. issue 1. 2017-01-10. PMID:26264384. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) has been reported to induce keratinocyte apoptosis in vitro by engaging its sole receptor of fibroblast growth factor-inducible 14 (fn14). |
2017-01-10 |
2023-08-13 |
Not clear |
| Sajad Mir, Farrah Ali, Deepika Chauhan, Rajesh Arora, Haider A Kha. Accumulation of reactivity to MBP sensitizes TRAIL mediated oligodendrocyte apoptosis in adult sub cortical white matter in a model for human multiple sclerosis. Metabolic brain disease. vol 31. issue 2. 2017-01-10. PMID:26477945. |
increased reactivity to mbp was studied to sensitize tnf related apoptosis-inducing ligand (trail) and other proinflammatory cytokines in a cumulative fashion leading to the caspase dependent apoptosis of oligodendrocytes and myelin loss. |
2017-01-10 |
2023-08-13 |
human |
| Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekera, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Gordon K Smyth, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silk. TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. eLife. vol 4. 2017-01-10. PMID:26701909. |
traf2 regulates tnf and nf-κb signalling to suppress apoptosis and skin inflammation independently of sphingosine kinase 1. |
2017-01-10 |
2023-08-13 |
mouse |
| Diego De Miguel, Ana Gallego-Lleyda, José M Ayuso, Aleksandra Pawlak, Blanca Conde, Ignacio Ochoa, Luis J Fernández, Alberto Anel, Luis Martinez-Losta. Improved Anti-Tumor Activity of Novel Highly Bioactive Liposome-Bound TRAIL in Breast Cancer Cells. Recent patents on anti-cancer drug discovery. vol 11. issue 2. 2017-01-09. PMID:26924736. |
apo2-ligand/trail, a member of the tnf cytokine superfamily capable of inducing apoptosis on tumor cells while sparing normal cells, is a promising anti-tumor agent. |
2017-01-09 |
2023-08-13 |
human |
| Katarzyna Ptaszynska-Kopczynska, Marta Marcinkiewicz-Siemion, Anna Lisowska, Ewa Waszkiewicz, Marcin Witkowski, Malgorzata Jasiewicz, Paula Miklasz, Piotr Jakim, Bogdan Galar, Wlodzimierz Jerzy Musial, Karol Adam Kaminsk. Alterations of soluble TWEAK and CD163 concentrations in patients with chronic heart failure. Cytokine. vol 80. 2016-12-29. PMID:26916171. |
a novel mediator from tnf family: soluble tumor necrosis factor-like weak inducer of apoptosis (stweak) along its soluble decoy receptor cd163 (scd163) recently has been investigated in other cardiovascular pathologies. |
2016-12-29 |
2023-08-13 |
human |
| N Yoon, M S Park, T Shigemoto, G Peltier, R H Le. Activated human mesenchymal stem/stromal cells suppress metastatic features of MDA-MB-231 cells by secreting IFN-β. Cell death & disease. vol 7. 2016-12-15. PMID:27077807. |
our recent study showed that human mesenchymal stem/stromal cells (hmscs) are activated to express tumor necrosis factor (tnf)-α-related apoptosis-inducing ligand (trail) by exposure to tnf-α and these activated hmscs effectively induce apoptosis in triple-negative breast cancer mda-mb-231 (mda) cells in vitro and in vivo. |
2016-12-15 |
2023-08-13 |
human |
| Diego De Miguel, Ana Gallego-Lleyda, José María Ayuso, Sandra Erviti-Ardanaz, Roberto Pazo-Cid, Celia del Agua, Luis José Fernández, Ignacio Ochoa, Alberto Anel, Luis Martinez-Losta. TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells. Nanotechnology. vol 27. issue 18. 2016-12-14. PMID:27001952. |
apo2-ligand/trail is a tnf family member able to induce apoptosis in tumor cells but not in normal cells. |
2016-12-14 |
2023-08-13 |
human |
| Zheng Zhenzhong, Yu Yafa, Liang Ji. Fibrinogen-like protein 2 gene silencing inhibits cardiomyocytes apoptosis, improves heart function of streptozotocin-induced diabetes rats and the molecular mechanism involved. Bioscience reports. vol 35. issue 3. 2016-12-13. PMID:26182381. |
we found that fgl2 gene silencing inhibits apoptosis and improves heart function of streptozotocin (stz)-induced diabetes rats, the possible mechanism maybe that fgl2 gene silencing reduces the tumour necrosis factor (tnf)±levels, decreases the expression of b-cell lymphoma-2 (bcl2), bcl-2-associated x (bax), toll-like receptors 4 (tlr4) and p38 mitogen-activated protein kinase (mapk). |
2016-12-13 |
2023-08-13 |
rat |
| Hande Yapislar, Eylem Taskin, Sule Ozdas, Demet Akin, Emine Sonme. Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite. Biological trace element research. vol 170. issue 2. 2016-12-13. PMID:26306587. |
after that, western blotting was performed in order to evaluate protein expression levels of several inflammation markers including il-1β, tumor necrosis factor (tnf)-α, and nuclear factor kappa b (nf-κb), and immunohistochemistry was carried out to detect apoptosis in liver cell culture. |
2016-12-13 |
2023-08-13 |
rat |
| Hande Yapislar, Eylem Taskin, Sule Ozdas, Demet Akin, Emine Sonme. Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite. Biological trace element research. vol 170. issue 2. 2016-12-13. PMID:26306587. |
the present study was pointed out that adr causes hepatotoxicity via apoptosis and/or inflammation processes resulting from initiator nf-κb and tnf which causes proinflammatory mediators such as il-1β. |
2016-12-13 |
2023-08-13 |
rat |
| H Fragoso-Loyo, Y Atisha-Fregoso, C A Nuñez-Alvarez, L Llorent. Utility of TWEAK to assess neuropsychiatric disease activity in systemic lupus erhytematosus. Lupus. vol 25. issue 4. 2016-12-13. PMID:26466614. |
the purpose of this study was to assess the utility of tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) in serum and cerebrospinal fluid (csf) as a biomarker in neuropsychiatric systemic lupus erythematosus (npsle). |
2016-12-13 |
2023-08-13 |
Not clear |
| Larissa M Coutinho, Erica L Vieira, Cynthia Dela Cruz, Maíra Casalechi, Antonio L Teixeira, Helen L Del Puerto, Fernando M Rei. Apoptosis modulation by activin A and follistatin in human endometrial stromal cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 32. issue 2. 2016-12-13. PMID:26494397. |
this study investigated the effects of activin a on total death and apoptosis rates and on tumor necrosis factor (tnf) release by human endometrial stromal cells (hesc). |
2016-12-13 |
2023-08-13 |
human |
| Larissa M Coutinho, Erica L Vieira, Cynthia Dela Cruz, Maíra Casalechi, Antonio L Teixeira, Helen L Del Puerto, Fernando M Rei. Apoptosis modulation by activin A and follistatin in human endometrial stromal cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 32. issue 2. 2016-12-13. PMID:26494397. |
apoptosis and total cell death were measured by flow cytometry, while tnf concentrations in culture media were quantified by elisa. |
2016-12-13 |
2023-08-13 |
human |
| Valvanera Fernández-Laso, Cristina Sastre, Jose M Valdivielso, Angels Betriu, Elvira Fernández, Jesús Egido, Jose L Martín-Ventura, Luis M Blanco-Coli. Soluble TWEAK and Major Adverse Cardiovascular Events in Patients with CKD. Clinical journal of the American Society of Nephrology : CJASN. vol 11. issue 3. 2016-12-13. PMID:26728587. |
soluble tnf-like weak inducer of apoptosis (stweak) is a proinflammatory cytokine belonging to the tnf superfamily. |
2016-12-13 |
2023-08-13 |
Not clear |
| Quanyin Hu, Wujin Sun, Yue Lu, Hunter N Bomba, Yanqi Ye, Tianyue Jiang, Ari J Isaacson, Zhen G. Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots. Nano letters. vol 16. issue 2. 2016-12-13. PMID:26785163. |
equipped with an acid-degradable modality, the resulting cs-ng can substantially release combinational anticancer drugs-tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) and antiangiogenic cilengitide toward the membrane of cancer cells and endothelial cells at the acidic tumor microenvironment, respectively. |
2016-12-13 |
2023-08-13 |
Not clear |
| Heiko Blaser, Catherine Dostert, Tak W Mak, Dirk Brenne. TNF and ROS Crosstalk in Inflammation. Trends in cell biology. vol 26. issue 4. 2016-12-13. PMID:26791157. |
the role of tnf as a master regulator in balancing cell survival, apoptosis and necroptosis has been extensively studied in various cell types and tissues. |
2016-12-13 |
2023-08-13 |
Not clear |
| Zeynep Kayaoglu Yildirim, Abdullah Sumnu, Neslihan Bademler, Elif Kilic, Gulay Sumnu, Serhat Karadag, Meltem Gursu, Aysegul Ozel, Gonca Batmaz, Seda Ates, Banu Dane, Savas Oztur. Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study. Disease markers. vol 2016. 2016-12-13. PMID:26989294. |
soluble tumor necrosis factor-like weak inducer of apoptosis (stweak) was recently introduced as a tnf related cytokine in various inflammatory and noninflammatory disorders. |
2016-12-13 |
2023-08-13 |
Not clear |
| A P Komarov, E A Komarova, K Green, L R Novototskaya, P S Baker, A Eroshkin, A L Osterman, A A Chenchick, C Frangou, A V Gudko. Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure. Cell death & disease. vol 7. 2016-11-14. PMID:26986512. |
by screening a lentiviral shrna library targeting for major components of human signaling pathways and known drug targets, we identified and validated both canonical as well as 52 novel mediators of fas and tnf ligand-induced apoptosis. |
2016-11-14 |
2023-08-13 |
mouse |
| A P Komarov, E A Komarova, K Green, L R Novototskaya, P S Baker, A Eroshkin, A L Osterman, A A Chenchick, C Frangou, A V Gudko. Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure. Cell death & disease. vol 7. 2016-11-14. PMID:26986512. |
remarkably, pharmacological inhibition of either sstr5 or ppp2r5a reduced apoptosis induced by either fasl or tnf in cultured cells and dramatically improved survival in several mouse models of alf. |
2016-11-14 |
2023-08-13 |
mouse |