Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Z G Liu, H Hsu, D V Goeddel, M Kari. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell. vol 87. issue 3. 1996-12-16. PMID:8898208. |
through its type 1 receptor (tnfr1), the cytokine tnf elicits an unusually wide range of biological responses, including inflammation, tumor necrosis, cell proliferation, differentiation, and apoptosis. |
1996-12-16 |
2023-08-12 |
Not clear |
Y Kato, A Morikawa, T Sugiyama, N Koide, G Z Jiang, K Takahashi, T Yokoch. Role of tumor necrosis factor-alpha and glucocorticoid on lipopolysaccharide (LPS)-induced apoptosis of thymocytes. FEMS immunology and medical microbiology. vol 12. issue 3-4. 1996-12-11. PMID:8745003. |
the injection of anti-tumor necrosis factor (tnf)-alpha antibody or ru38486, a glucocorticoid receptor antagonist, into mice definitely inhibited lps-induced apoptosis of thymocytes. |
1996-12-11 |
2023-08-12 |
mouse |
A E Dear, Y Shen, M Rüegg, R L Medcal. Molecular mechanisms governing tumor-necrosis-factor-mediated regulation of plasminogen-activator inhibitor type-2 gene expression. European journal of biochemistry. vol 241. issue 1. 1996-12-05. PMID:8898893. |
plasminogen-activator inhibitor type 2 (pai-2), a serine protease inhibitor involved in the regulation of urokinase-dependent proteolysis, is also implicated in the inhibition of tumor-necrosis-factor-(tnf)-mediated apoptosis. |
1996-12-05 |
2023-08-12 |
cat |
S Gon, T Gatanaga, F Send. Involvement of two types of TNF receptor in TNF-alpha induced neutrophil apoptosis. Microbiology and immunology. vol 40. issue 6. 1996-12-04. PMID:8839434. |
involvement of two types of tnf receptor in tnf-alpha induced neutrophil apoptosis. |
1996-12-04 |
2023-08-12 |
human |
B S Polla, A Cossarizz. Stress proteins in inflammation. EXS. vol 77. 1996-12-03. PMID:8856986. |
we propose that mitochondria are a key organelle in determining the outcome of inflammation, because they are both the cellular "switchboard" for apoptosis and a selective target for the protective effects of hsp against the cytotoxic effects of tnf alpha and ros. |
1996-12-03 |
2023-08-12 |
Not clear |
R Ramírez, J Carracedo, M Castedo, N Zamzami, G Kroeme. CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways. Cellular immunology. vol 172. issue 2. 1996-12-03. PMID:8964080. |
both lps and anti-cd69 are sufficient on their own to activate cells, as determined by tnf production, no generation, or arachidonic acid metabolism, but neither lps nor anti-cd69 can induce apoptosis on their own. |
1996-12-03 |
2023-08-12 |
human |
A Peralta Soler, J M Mullin, K A Knudsen, C W Maran. Tissue remodeling during tumor necrosis factor-induced apoptosis in LLC-PK1 renal epithelial cells. The American journal of physiology. vol 270. issue 5 Pt 2. 1996-11-27. PMID:8928850. |
the cytokine tumor necrosis factor-alpha (tnf) increases the frequency of apoptosis in confluent renal epithelial llc-pk1 cells, an effect that can be blocked by an anti-tnfr1 monoclonal antibody. |
1996-11-27 |
2023-08-12 |
Not clear |
Y Takeda, S Gon, H Takei, F Send. [TNF/TNFR gene and apoptosis]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741683. |
the possible role of these signal transduction pathways for apoptosis induced by tnf is discussed. |
1996-11-26 |
2023-08-12 |
Not clear |
T Ohtsubo, S Kamada, Y Tsujimot. [Inhibition of apoptosis by a baculovirus p35 gene]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741686. |
p35 can also inhibit developmentally programmed cell death in caenorhabditis elegans and drosophila, mammalian neuronal cell death induced by serum or ngf deprivation, and fas- and tumor necrosis factor (tnf)-induced apoptosis in mammalian cells, indicating that p35 may interrupt an evolutionally conserved component of the death machinery. |
1996-11-26 |
2023-08-12 |
caenorhabditis_elegans |
H Cao, J Mattison, Y Zhao, N Joki, M Grasso, N S Chan. Regulation of tumor necrosis factor-and Fas-mediated apoptotic cell death by a novel cDNA TR2L. Biochemical and biophysical research communications. vol 227. issue 1. 1996-11-25. PMID:8858135. |
a novel cdna, tr2l, isolated from murine nih 3t3 fibroblasts, was found to modulate tumor necrosis factor (tnf)-mediated apoptosis in murine l929 fibrosarcoma cells. |
1996-11-25 |
2023-08-12 |
rat |
G Monastra, A Cabrelle, A Zambon, A Rosato, B Macino, D Collavo, P Zanovell. Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells. Cellular immunology. vol 171. issue 1. 1996-11-22. PMID:8660844. |
membrane form of tnf alpha induces both cell lysis and apoptosis in susceptible target cells. |
1996-11-22 |
2023-08-12 |
Not clear |
P Wattre, V Bert, D Hobe. [Apoptosis and human viral infections]. Annales de biologie clinique. vol 54. issue 5. 1996-11-18. PMID:8869358. |
moreover, an accelerated t-cell apoptosis in hiv-infected individuals is characterized by (i) hiv gp120-cd4+ cross-linking and subsequent aberrant signaling of t-cells, (ii) involvement of tnf alpha-fas/apo-1 (tnf-r) binding, (iii) involvement of accessory cells as an apoptosis inducer and as a result of defective antigen presentation, (iv) possible superantigen activity induced by hiv products and cofactors. |
1996-11-18 |
2023-08-12 |
human |
R U Jänicke, X Y Lin, F H Lee, A G Porte. Cyclin D3 sensitizes tumor cells to tumor necrosis factor-induced, c-Myc-dependent apoptosis. Molecular and cellular biology. vol 16. issue 10. 1996-11-15. PMID:8816437. |
c-myc is an important mediator of apoptosis in cytokine- or serum-deprived cells and sensitizes various cell types to tumor necrosis factor alpha (tnf) cytotoxicity. |
1996-11-15 |
2023-08-12 |
Not clear |
P Krajcsi, T Dimitrov, T W Hermiston, A E Tollefson, T S Ranheim, S B Vande Pol, A H Stephenson, W S Wol. The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid. Journal of virology. vol 70. issue 8. 1996-11-07. PMID:8763993. |
the adenovirus e3-14.7k protein and the e3-10.4k/14.5k complex of proteins, which independently inhibit tumor necrosis factor (tnf)-induced apoptosis, also independently inhibit tnf-induced release of arachidonic acid. |
1996-11-07 |
2023-08-12 |
mouse |
P Krajcsi, T Dimitrov, T W Hermiston, A E Tollefson, T S Ranheim, S B Vande Pol, A H Stephenson, W S Wol. The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid. Journal of virology. vol 70. issue 8. 1996-11-07. PMID:8763993. |
tnf activation of the 85-kda cytosolic phospholipase a2 (cpla2) is thought to be essential for tnf cytolysis (i.e.,tnf-induced apoptosis). |
1996-11-07 |
2023-08-12 |
mouse |
K Noguchi, M Naito, S Kataoka, S Yonehara, T Tsuru. A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 6. issue 10. 1996-10-23. PMID:8845304. |
human monocytic leukemia u937 cells readily undergo apoptosis when cells are treated with various stimuli including antitumor agents, tumor necrosis factor (tnf)-alpha and anti-fas antibody. |
1996-10-23 |
2023-08-12 |
human |
J A Maier, D Morelli, S Ménard, M I Colnaghi, A Balsar. Tumor-necrosis-factor-induced fibroblast growth factor-1 acts as a survival factor in a transformed endothelial cell line. The American journal of pathology. vol 149. issue 3. 1996-10-17. PMID:8780398. |
here we report that tumor necrosis factor (tnf)-alpha induces apoptosis of human endothelial cells derived from the umbilical vein in a dose-dependent fashion. |
1996-10-17 |
2023-08-12 |
human |
H K Sytwu, R S Liblau, H O McDevit. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity. vol 5. issue 1. 1996-10-10. PMID:8758891. |
tcrtg-+/+ or tcrtg-lpr/lpr mice injected with murine tnf-blocking mab (tn3) showed rapid apoptosis of thymocytes after ha stimulation, indicating that death signaling through fas and tnf receptors is not essential for ha-induced thymocyte deletion. |
1996-10-10 |
2023-08-12 |
mouse |
W Malorni, G Rainaldi, E Tritarelli, R Rivabene, M Cianfriglia, M Lehnert, G Donelli, C Peschele, U Test. Tumor necrosis factor alpha is a powerful apoptotic inducer in lymphoid leukemic cells expressing the P-170 glycoprotein. International journal of cancer. vol 67. issue 2. 1996-09-16. PMID:8760594. |
in the present study we report that the cytotoxicity mediated by tumor necrosis factor alpha (tnf alpha) in mdr variants of the human t-lymphoblastoid cem cell line is associated with apoptosis (programmed cell death). |
1996-09-16 |
2023-08-12 |
human |
W Malorni, G Rainaldi, E Tritarelli, R Rivabene, M Cianfriglia, M Lehnert, G Donelli, C Peschele, U Test. Tumor necrosis factor alpha is a powerful apoptotic inducer in lymphoid leukemic cells expressing the P-170 glycoprotein. International journal of cancer. vol 67. issue 2. 1996-09-16. PMID:8760594. |
susceptibility of mdr cells to apoptosis was increased upon cycloheximide + tnf alpha sequential treatment, whereby the impairment of protein synthesis due to the former agent was followed by the effect of cytokine exposure. |
1996-09-16 |
2023-08-12 |
human |