| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Weller, U Malipiero, A Aguzzi, J C Reed, A Fontan. Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. The Journal of clinical investigation. vol 95. issue 6. 1995-07-06. PMID:7539458. |
preexposure of the glioma cell lines to the cytokines, ifn gamma and tnf alpha, which sensitize for fas/apo-1-dependent killing, partially overcame bcl-2-mediated rescue from apoptosis, suggesting that multimodality immunotherapy involving cytokines and fas/apo-1 targeting might eventually provide a promising approach to the treatment of human malignant gliomas. |
1995-07-06 |
2023-08-12 |
human |
| K M Debatin, P H Kramme. Resistance to APO-1 (CD95) induced apoptosis in T-ALL is determined by a BCL-2 independent anti-apoptotic program. Leukemia. vol 9. issue 5. 1995-07-06. PMID:7539514. |
apoptosis can be induced by the monoclonal antibody anti-apo-1 directed against the cell surface receptor apo-1, a member of the nerve growth factor (ngf) receptor/tumor necrosis factor (tnf) receptor superfamily. |
1995-07-06 |
2023-08-12 |
Not clear |
| S Tabibzadeh, E Zupi, A Babaknia, R Liu, D Marconi, C Romanin. Site and menstrual cycle-dependent expression of proteins of the tumour necrosis factor (TNF) receptor family, and BCL-2 oncoprotein and phase-specific production of TNF alpha in human endometrium. Human reproduction (Oxford, England). vol 10. issue 2. 1995-07-05. PMID:7539446. |
in addition, to relate production of tnf alpha to the development of apoptosis, the amount of tnf alpha released by human endometrium was measured. |
1995-07-05 |
2023-08-12 |
human |
| S Tabibzadeh, E Zupi, A Babaknia, R Liu, D Marconi, C Romanin. Site and menstrual cycle-dependent expression of proteins of the tumour necrosis factor (TNF) receptor family, and BCL-2 oncoprotein and phase-specific production of TNF alpha in human endometrium. Human reproduction (Oxford, England). vol 10. issue 2. 1995-07-05. PMID:7539446. |
therefore, endometrial epithelium by virtue of expression of receptors of tnf alpha as well as fas protein is properly poised to respond to ligand signals that regulate apoptosis. |
1995-07-05 |
2023-08-12 |
human |
| S Tabibzadeh, E Zupi, A Babaknia, R Liu, D Marconi, C Romanin. Site and menstrual cycle-dependent expression of proteins of the tumour necrosis factor (TNF) receptor family, and BCL-2 oncoprotein and phase-specific production of TNF alpha in human endometrium. Human reproduction (Oxford, England). vol 10. issue 2. 1995-07-05. PMID:7539446. |
induction of apoptosis in endometrial epithelium and menstrual shedding may be related to loss of the protective effect of bcl-2 as well as to the amount of tnf alpha. |
1995-07-05 |
2023-08-12 |
human |
| P D Katsikis, E S Wunderlich, C A Smith, L A Herzenberg, L A Herzenber. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. The Journal of experimental medicine. vol 181. issue 6. 1995-06-23. PMID:7539037. |
antibodies against other members of the tumor necrosis factor (tnf)/nerve growth factor receptor family such as cd27, cd30, cd40, 4-1bb, p55 tnf receptor, p75 tnf receptor, and tnf receptor-related protein did not result in any increase of t cell apoptosis above that spontaneously observed in hiv+ individuals. |
1995-06-23 |
2023-08-12 |
human |
| B B Aggarwal, S Singh, R LaPushin, K Totpa. Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor. FEBS letters. vol 364. issue 1. 1995-06-22. PMID:7538467. |
recent cloning of the cdna for fas/apo-1 and its ligand has revealed that they belong to the tumor necrosis factor (tnf) receptor and tnf family, respectively, and play an important role in apoptosis (programmed cell death). |
1995-06-22 |
2023-08-12 |
human |
| K Iwasaki, S A Toms, G H Barnett, M L Estes, M K Gupta, B P Barn. Inhibitory effects of tamoxifen and tumor necrosis factor alpha on human glioblastoma cells. Cancer immunology, immunotherapy : CII. vol 40. issue 4. 1995-06-22. PMID:7750120. |
data suggest that tnf alpha and tamoxifen in combination display growth-regulatory properties, which (a) are more inhibitory to human glioblastoma cells than either agent alone, (b) do not affect non-neoplastic glia, (c) do not require either estrogen/progesterone receptors or alteration of external tnf alpha receptors, and (d) may involve apoptosis. |
1995-06-22 |
2023-08-12 |
human |
| G Baier-Bitterlich, D Fuchs, C Murr, G Reibnegger, G Werner-Felmayer, R Sgonc, G Böck, M P Dierich, H Wachte. Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-alpha induced programmed cell death. FEBS letters. vol 364. issue 2. 1995-06-22. PMID:7750578. |
we have therefore investigated the effect of neopterin-derivatives on tnf alpha induced apoptosis of the monocyte-like cell line u937. |
1995-06-22 |
2023-08-12 |
Not clear |
| G Baier-Bitterlich, D Fuchs, C Murr, G Reibnegger, G Werner-Felmayer, R Sgonc, G Böck, M P Dierich, H Wachte. Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-alpha induced programmed cell death. FEBS letters. vol 364. issue 2. 1995-06-22. PMID:7750578. |
our results imply that in combination with tnf alpha high concentrations of 7,8-dihydroneopterin enhances apoptosis due to oxidative stress on cells. |
1995-06-22 |
2023-08-12 |
Not clear |
| M Leist, F Gantner, I Bohlinger, G Tiegs, P G Germann, A Wende. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. The American journal of pathology. vol 146. issue 5. 1995-06-15. PMID:7538266. |
these results demonstrate the causal role of tnf in endotoxin-induced hepatic apoptosis. |
1995-06-15 |
2023-08-12 |
mouse |
| T Suda, T Okazaki, Y Naito, T Yokota, N Arai, S Ozaki, K Nakao, S Nagat. Expression of the Fas ligand in cells of T cell lineage. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 8. 1995-05-11. PMID:7706720. |
fas ligand (fasl) is a membrane-type cytokine belonging to the tnf family, and induces apoptosis through its cell-surface receptor, fas. |
1995-05-11 |
2023-08-12 |
mouse |
| S Bursten, R Weeks, J West, T Le, T Wilson, D Porubek, J A Bianco, J W Singer, G C Ric. Potential role for phosphatidic acid in mediating the inflammatory responses to TNF alpha and IL-1 beta. Circulatory shock. vol 44. issue 1. 1995-05-05. PMID:7704934. |
tnf alpha-induced sphingomyelin hydrolysis, plc-mediated pc hydrolysis, and dg kinase-mediated pa formation or tnf alpha-induced nf-kappa b activation and apoptosis are not inhibited by lsf. |
1995-05-05 |
2023-08-12 |
Not clear |
| P Vandenabeele, W Declercq, B Vanhaesebroeck, J Grooten, W Fier. Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 6. 1995-04-06. PMID:7876558. |
both tnf receptors are required for tnf-mediated induction of apoptosis in pc60 cells. |
1995-04-06 |
2023-08-12 |
human |
| P Vandenabeele, W Declercq, B Vanhaesebroeck, J Grooten, W Fier. Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 6. 1995-04-06. PMID:7876558. |
both receptors are signal transducing because simultaneous triggering of htnf-r55 and htnf-r75 by agonistic mabs or by tnf-r-specific tnf muteins induced similar levels of apoptosis as wild-type htnf. |
1995-04-06 |
2023-08-12 |
human |
| C Voelkel-Johnson, A J Entingh, W S Wold, L R Gooding, S M Laste. Activation of intracellular proteases is an early event in TNF-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 4. 1995-02-27. PMID:7836755. |
we also found evidence of proteolysis in c3ha cells sensitized to tnf by the adenovirus dl758 (which lacks the e3 14.7-kda resistance gene) suggesting that protease activation is common in tnf-induced apoptosis. |
1995-02-27 |
2023-08-12 |
Not clear |
| M Higuchi, S Singh, B B Aggarwa. Characterization of the apoptotic effects of human tumor necrosis factor: development of highly rapid and specific bioassay for human tumor necrosis factor and lymphotoxin using human target cells. Journal of immunological methods. vol 178. issue 2. 1995-02-27. PMID:7836779. |
treatment of cells to tnf lead to apoptosis as indicated by thymidine release, dna laddering on agarose gels and morphological alterations. |
1995-02-27 |
2023-08-12 |
human |
| J Dhein, H Walczak, C Bäumler, K M Debatin, P H Kramme. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) Nature. vol 373. issue 6513. 1995-02-22. PMID:7530335. |
autocrine t-cell suicide mediated by apo-1/(fas/cd95) the apo-1/(fas/cd95) cell surface receptor is a member of the nerve growth factor (ngf)/tumour necrosis factor (tnf) receptor superfamily and mediates apoptosis. |
1995-02-22 |
2023-08-12 |
mouse |
| M Leist, F Gantner, S Jilg, A Wende. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 3. 1995-02-16. PMID:7822799. |
activation of the 55 kda tnf receptor is necessary and sufficient for tnf-induced liver failure, hepatocyte apoptosis, and nitrite release. |
1995-02-16 |
2023-08-12 |
mouse |
| F Rosselli, A Ridet, T Soussi, E Duchaud, C Alapetite, E Moustacch. p53-dependent pathway of radio-induced apoptosis is altered in Fanconi anemia. Oncogene. vol 10. issue 1. 1995-02-14. PMID:7824283. |
since growth factor deprivation, tnf alpha treatment or dna damage can trigger apoptosis, we monitored the apoptotic response of fa cell lines. |
1995-02-14 |
2023-08-12 |
human |