| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Enari, H Hug, M Hayakawa, F Ito, Y Nishimura, S Nagat. Different apoptotic pathways mediated by Fas and the tumor-necrosis-factor receptor. Cytosolic phospholipase A2 is not involved in Fas-mediated apoptosis. European journal of biochemistry. vol 236. issue 2. 1996-06-03. PMID:8612626. |
these results indicated that cpla2 is required for tnf-induced apoptosis, whereas it is dispensable for fas-mediated apoptosis, and suggested that the tnf receptor and fas use different signaling pathways for apoptosis. |
1996-06-03 |
2023-08-12 |
mouse |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
to determine if tumor necrosis factor (tnf)-mediated apoptosis affects cells at defined stages of the cell cycle, wehi-164/2f (wehi) cells were synchronized at g0-g1 after 3-day cultures in medium containing rpmi 1640 and 0.5% fcs (rpmi-0.5% fcs). |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
the arrested wehi cells (60-75% in g0-g1) showed increased sensitivity to tnf killing, measured as 48-h 3-(5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assays, and 15-h apoptosis by propidium iodide staining and flow cytometry analysis. |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
however, tnf inhibited wehi dna synthesis as early as 1 h after treatment, and inhibition was proportionate to sensitivity to tnf-induced apoptosis. |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
these results show that tnf-induced apoptosis of wehi cells is connected to cell cycle events; wehi targets receive the tnf cytotoxic signal mainly at the g1-s boundary and begin to die by apoptosis as they exit from s phase. |
1996-05-13 |
2023-08-12 |
Not clear |
| M Verheij, R Bose, X H Lin, B Yao, W D Jarvis, S Grant, M J Birrer, E Szabo, L I Zon, J M Kyriakis, A Haimovitz-Friedman, Z Fuks, R N Kolesnic. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. vol 380. issue 6569. 1996-04-22. PMID:8598911. |
the sphingomyelin pathway, initiated by hydrolysis of the phospholipid sphingomyelin in the cell membrane to generate the second messenger ceramide, is thought to mediate apoptosis in response to tumour-necrosis factor (tnf)-alpha, to fas ligand and to x-rays. |
1996-04-22 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
here we report that tnf alpha mediates apoptosis in kc and sinusoidal endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
tnf alpha antibody blocked apoptosis in both kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
reducing transmembrane tnf alpha expressed on kc also led to a decrease in endothelial cell apoptosis, suggesting that transmembrane tnf alpha is implicated in the cell-to-cell contact mechanism of induction of apoptosis. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
thus, tnf alpha mediates apoptosis in kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| E S Bour, L K Ward, G A Cornman, H C Iso. Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term culture. The American journal of pathology. vol 148. issue 2. 1996-03-11. PMID:8579111. |
we demonstrated that treatment with tumor necrosis factor (tnf)-alpha induced apoptosis (detected morphologically and by formation of an oligonucleosomal dna ladder) only in hepatocytes that had been subjected to dimethylsulfoxide removal. |
1996-03-11 |
2023-08-12 |
rat |
| D J MacEwa. Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis. FEBS letters. vol 379. issue 1. 1996-03-06. PMID:8566235. |
elevated cpla2 levels as a mechanism by which the p70 tnf and p75 ngf receptors enhance apoptosis. |
1996-03-06 |
2023-08-12 |
Not clear |
| M Ido, K Hayashi, S Kato, H Ogawa, Y Komada, Y W Zhau, X L Zhang, M Sakurai, K Suzuk. Isolation and characterisation of Kasumi-1 human myeloid leukaemia cell line resistant to tumour necrosis factor alpha-induced apoptosis. British journal of cancer. vol 73. issue 3. 1996-03-05. PMID:8562342. |
tumour necrosis factor (tnf)-alpha induces apoptosis in a human acute myeloid leukaemia cell line, kasumi-1. |
1996-03-05 |
2023-08-12 |
human |
| H Hsu, H B Shu, M G Pan, D V Goedde. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. vol 84. issue 2. 1996-03-01. PMID:8565075. |
tumor necrosis factor (tnf) can induce apoptosis and activate nf-kappa b through signaling cascades emanating from tnf receptor 1 (tnfr1). |
1996-03-01 |
2023-08-12 |
Not clear |
| M Jäättelä, H Mouritzen, F Elling, L Basthol. A20 zinc finger protein inhibits TNF and IL-1 signaling. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8557994. |
overexpression of a20 in mcf7 breast carcinoma cells or in wehi-s fibrosarcoma cells inhibits apoptosis induced by tnf, whereas cytotoxicity induced by anti-fas (anti-cd95); lymphokine-activated killer (lak) cells, serum starvation, oxidative stress, or okadaic acid is not inhibited. |
1996-02-27 |
2023-08-12 |
Not clear |
| M Ostad, W P Shu, L Kong, B C Li. Ha-ras oncogene expression abrogates a pH dependent endonuclease activity of apoptosis in normal rat kidney cells. Cancer letters. vol 98. issue 2. 1996-02-26. PMID:8556706. |
furthermore, dna isolated from nrk, c127, hc127, but not nrk-ha cells revealed the presence of dna fragmentation 'ladders' indicative of successful apoptosis when the cells were incubated with tnf. |
1996-02-26 |
2023-08-12 |
rat |
| M Ostad, W P Shu, L Kong, B C Li. Ha-ras oncogene expression abrogates a pH dependent endonuclease activity of apoptosis in normal rat kidney cells. Cancer letters. vol 98. issue 2. 1996-02-26. PMID:8556706. |
to determine the possible mechanism in which the ras oncogene may have protected the nrk-ha cells from tnf mediated cytotoxicity and apoptosis, total nuclear endonucleases from the nrk cells and the ras transfectant nrk-ha cells were isolated. |
1996-02-26 |
2023-08-12 |
rat |
| D Yin, S Kondo, G H Barnett, T Morimura, J Takeuch. Tumor necrosis factor-alpha induces p53-dependent apoptosis in rat glioma cells. Neurosurgery. vol 37. issue 4. 1996-02-26. PMID:8559306. |
in this study, we demonstrated that tumor necrosis factor (tnf)-alpha inhibited the viability of rat glioma (c6) cells and induced apoptosis but did not affect the viability of rat newborn brain, mainly astroglial cells. |
1996-02-26 |
2023-08-12 |
rat |
| G Eissner, F Kohlhuber, M Grell, M Ueffing, P Scheurich, A Hieke, G Multhoff, G W Bornkamm, E Holle. Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin. Blood. vol 86. issue 11. 1996-01-11. PMID:7492776. |
using neutralizing antibodies against tumor necrosis factor-alpha (tnf), we could show crucial involvement of tnf in the lps-mediated enhancement of ir-induced apoptosis, but not in the ir-induced apoptosis per se. |
1996-01-11 |
2023-08-12 |
human |
| H Dong, R Xing, L Gu. [Apoptosis of tumor cells in lectin-dependent lymphokine-activated killer cell-mediated cytotoxicity]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. vol 17. issue 4. 1995-12-06. PMID:7587887. |
as the tnf-resistant tumor cell lines such as sw1116 cells and raji cells were also triggered to apoptosis, other factors than tnf would play the role. |
1995-12-06 |
2023-08-12 |
human |