| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S R Wiley, K Schooley, P J Smolak, W S Din, C P Huang, J K Nicholl, G R Sutherland, T D Smith, C Rauch, C A Smit. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity. vol 3. issue 6. 1996-09-16. PMID:8777713. |
identification and characterization of a new member of the tnf family that induces apoptosis. |
1996-09-16 |
2023-08-12 |
human |
| S Gamen, I Marzo, A Anel, A Piñeiro, J Nava. CPP32 inhibition prevents Fas-induced ceramide generation and apoptosis in human cells. FEBS letters. vol 390. issue 2. 1996-09-10. PMID:8706867. |
intracellular activation of sphingomyelinase, leading to ceramide generation, and ice-like proteases have been implicated in tnf and fas-induced apoptosis, but the links between these intracellular apoptotic mediators remain undefined. |
1996-09-10 |
2023-08-12 |
human |
| A Bettaieb, M Record, M G Côme, A C Bras, H Chap, G Laurent, J P Jaffrézo. Opposite effects of tumor necrosis factor alpha on the sphingomyelin-ceramide pathway in two myeloid leukemia cell lines: role of transverse sphingomyelin distribution in the plasma membrane. Blood. vol 88. issue 4. 1996-09-05. PMID:8695867. |
our results show that tnf alpha induced apoptosis in u937 but not in kg1a cells. |
1996-09-05 |
2023-08-12 |
Not clear |
| T Kato, Y Takeda, T Nakada, F Send. Inhibition by dexamethasone of human neutrophil apoptosis in vitro. Natural immunity. vol 14. issue 4. 1996-09-05. PMID:8696009. |
the decrease in sensitivity to tnf-alpha-induced apoptosis cannot be ascribed to a down-modulation of tnf receptors on these cells. |
1996-09-05 |
2023-08-12 |
human |
| E Fujita, T Mukasa, T Tsukahara, K Arahata, S Omura, T Momo. Enhancement of CPP32-like activity in the TNF-treated U937 cells by the proteasome inhibitors. Biochemical and biophysical research communications. vol 224. issue 1. 1996-08-29. PMID:8694836. |
cpp32, which is most closely related to ced-3 in the apoptotic protease in c. elegance, is activated during apoptosis induced by anti-fas and tnf. |
1996-08-29 |
2023-08-12 |
Not clear |
| L Glickstein, S Macphail, O Stutma. Uncoupling IL-2 production from apoptosis and TNF production by changing the signal through the TCR. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 6. 1996-08-26. PMID:8690893. |
uncoupling il-2 production from apoptosis and tnf production by changing the signal through the tcr. |
1996-08-26 |
2023-08-12 |
Not clear |
| L Glickstein, S Macphail, O Stutma. Uncoupling IL-2 production from apoptosis and TNF production by changing the signal through the TCR. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 6. 1996-08-26. PMID:8690893. |
plastic-bound anti-cd3, in contrast, stimulated tnf production, g1 arrest, and apoptosis by the t hybridoma. |
1996-08-26 |
2023-08-12 |
Not clear |
| L Glickstein, S Macphail, O Stutma. Uncoupling IL-2 production from apoptosis and TNF production by changing the signal through the TCR. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 6. 1996-08-26. PMID:8690893. |
although tnf production was correlated with apoptosis, anti-tnf treatment did not prevent cell death or g1 arrest. |
1996-08-26 |
2023-08-12 |
Not clear |
| E Park, C I Kalunta, T T Nguyen, C L Wang, F S Chen, C K Lin, J S Kaptein, P M La. TNF-alpha inhibits anti-IgM-mediated apoptosis in Ramos cells. Experimental cell research. vol 226. issue 1. 1996-08-22. PMID:8660933. |
since tnf receptor and cd40 belong to the tnf receptor superfamily and anti-cd40 is a known inhibitor of apoptosis, we tested for tnf-alpha's effects on the inhibition of apoptosis induced by anti-igm. |
1996-08-22 |
2023-08-12 |
Not clear |
| E Park, C I Kalunta, T T Nguyen, C L Wang, F S Chen, C K Lin, J S Kaptein, P M La. TNF-alpha inhibits anti-IgM-mediated apoptosis in Ramos cells. Experimental cell research. vol 226. issue 1. 1996-08-22. PMID:8660933. |
although anti-igm induces both tnf-alpha secretion and tnf receptors in ramos cells, the concentration of secreted tnf-alpha is too low to affect apoptosis. |
1996-08-22 |
2023-08-12 |
Not clear |
| M Higuchi, S Singh, J P Jaffrezou, B B Aggarwa. Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 1. 1996-08-16. PMID:8683130. |
previously we have shown that treatment of ml-1a cells with tnf in the presence of cycloheximide triggers apoptosis within 90 min. |
1996-08-16 |
2023-08-12 |
Not clear |
| M Higuchi, S Singh, J P Jaffrezou, B B Aggarwa. Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 1. 1996-08-16. PMID:8683130. |
even though ceramides by themselves did not mimic tnf, we found that sr33557 inhibited tnf-induced apoptosis and the addition of ceramide reversed this effect, indicating that ceramide generated by acidic smase is involved in tnf action. |
1996-08-16 |
2023-08-12 |
Not clear |
| V Modur, G A Zimmerman, S M Prescott, T M McIntyr. Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. The Journal of biological chemistry. vol 271. issue 22. 1996-08-15. PMID:8662702. |
ceramide generation by stimulated sphingomyelinase activity has been implicated in tumor necrosis factor alpha (tnf) signaling of apoptosis and differentiation. |
1996-08-15 |
2023-08-12 |
Not clear |
| R M Pitti, S A Marsters, S Ruppert, C J Donahue, A Moore, A Ashkenaz. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. The Journal of biological chemistry. vol 271. issue 22. 1996-08-15. PMID:8663110. |
the effect of apo-2l is not inhibited by soluble fas/apo-1 and tnf receptors; moreover, expression of human fas/apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-fas/apo-1 antibody, does not confer sensitivity to apo-2l. |
1996-08-15 |
2023-08-12 |
mouse |
| H D Dong, Y Kimoto, S Takai, T Taguch. Apoptosis as a mechanism of lectin-dependent monocyte-mediated cytotoxicity. Immunological investigations. vol 25. issue 1-2. 1996-08-15. PMID:8675235. |
these results suggest that the presence of lectin molecules on the surface of monocytes and tumour cells may bring the two cells together, thus facilitating the induction of apoptosis in target cells by triggering the production of cytolytic factors (tnf and no) and the modification of target cell surface antigen (hla-dr). |
1996-08-15 |
2023-08-12 |
human |
| O Cuvillier, G Pirianov, B Kleuser, P G Vanek, O A Coso, S Gutkind, S Spiege. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature. vol 381. issue 6585. 1996-08-01. PMID:8657285. |
ceramide is an important regulatory participant of programmed cell death (apoptosis) induced by tumour-necrosis factor (tnf)-alpha and fas ligand, members of the tnf superfamily. |
1996-08-01 |
2023-08-12 |
human |
| T Kohno, Y Yamada, T Hata, H Mori, M Yamamura, M Tomonaga, Y Urata, S Goto, T Kond. Relation of oxidative stress and glutathione synthesis to CD95(Fas/APO-1)-mediated apoptosis of adult T cell leukemia cells. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 12. 1996-07-25. PMID:8648118. |
as cd95 and tnf receptor are similar, and tnf/tnf receptor binding induces oxygen radicals, the involvement of oxidant and antioxidant systems in cd95-mediated apoptosis has been examined. |
1996-07-25 |
2023-08-12 |
Not clear |
| U Brinkmann, E Brinkmann, M Gallo, U Scherf, I Pasta. Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis. Biochemistry. vol 35. issue 21. 1996-07-17. PMID:8639641. |
the observation that cas antisense can interfere with apoptosis mediated by tnf and adp-ribosylating toxins suggests that cas may play a role in selected pathways of apoptosis. |
1996-07-17 |
2023-08-12 |
human |
| M Mizuno, J Yoshid. Tumor necrosis factor-alpha gene transfer augments anti-Fas antibody-mediated apoptosis in human glioma cells. Japanese journal of cancer research : Gann. vol 87. issue 5. 1996-07-17. PMID:8641993. |
to effectively induce apoptosis in human glioma cells, we tried to transfer the tumor necrosis factor (tnf)-alpha gene into glioma cells to produce tnf-alpha locally in these cells. |
1996-07-17 |
2023-08-12 |
human |
| S C Wright, H Zheng, J Zhon. Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24). FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 10. issue 2. 1996-07-12. PMID:8641566. |
although this subclone was selected by growth in tnf, it was unexpectedly found to resist apoptosis induced by uv light, but was still sensitive to anti-fas-induced dna fragmentation. |
1996-07-12 |
2023-08-12 |
Not clear |