| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Yoo, R T Stone, C W Beatti. Cloning and characterization of the bovine Fas. DNA and cell biology. vol 15. issue 3. 1996-07-09. PMID:8634151. |
fas (apo-1, cd95), a member of the tumor necrosis factor (tnf) receptor superfamily, is a cell membrane protein that mediates programmed cell death (apoptosis). |
1996-07-09 |
2023-08-12 |
mouse |
| E A Sweeney, C Sakakura, T Shirahama, A Masamune, H Ohta, S Hakomori, Y Igarash. Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines. International journal of cancer. vol 66. issue 3. 1996-06-18. PMID:8621258. |
in earlier studies we presented data which indicated that sphingosine (sph) itself was increased during apoptosis induced by phorbol myristate acetate (pma) in hl60 cells and tumor necrosis factor (tnf) in neutrophils, and when added exogenously was able to induce apoptosis. |
1996-06-18 |
2023-08-12 |
human |
| H Hsu, J Huang, H B Shu, V Baichwal, D V Goedde. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity. vol 4. issue 4. 1996-06-06. PMID:8612133. |
the death domain of tumor necrosis factor (tnf) receptor-1 (tnfr1) triggers distinct signaling pathways leading to apoptosis and nf-kappa b activation through its interaction with the death domain protein tradd. |
1996-06-06 |
2023-08-12 |
Not clear |
| H Hsu, J Huang, H B Shu, V Baichwal, D V Goedde. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity. vol 4. issue 4. 1996-06-06. PMID:8612133. |
however, expression of the death domain of rip induces apoptosis, but potently inhibits nf-kappa b activation by tnf. |
1996-06-06 |
2023-08-12 |
Not clear |
| H Hsu, J Huang, H B Shu, V Baichwal, D V Goedde. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity. vol 4. issue 4. 1996-06-06. PMID:8612133. |
these results suggest that distinct domains of rip participate in the tnf signaling cascades leading to apoptosis and nf-kappa b activation. |
1996-06-06 |
2023-08-12 |
Not clear |
| M Enari, H Hug, M Hayakawa, F Ito, Y Nishimura, S Nagat. Different apoptotic pathways mediated by Fas and the tumor-necrosis-factor receptor. Cytosolic phospholipase A2 is not involved in Fas-mediated apoptosis. European journal of biochemistry. vol 236. issue 2. 1996-06-03. PMID:8612626. |
these results indicated that cpla2 is required for tnf-induced apoptosis, whereas it is dispensable for fas-mediated apoptosis, and suggested that the tnf receptor and fas use different signaling pathways for apoptosis. |
1996-06-03 |
2023-08-12 |
mouse |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
to determine if tumor necrosis factor (tnf)-mediated apoptosis affects cells at defined stages of the cell cycle, wehi-164/2f (wehi) cells were synchronized at g0-g1 after 3-day cultures in medium containing rpmi 1640 and 0.5% fcs (rpmi-0.5% fcs). |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
the arrested wehi cells (60-75% in g0-g1) showed increased sensitivity to tnf killing, measured as 48-h 3-(5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assays, and 15-h apoptosis by propidium iodide staining and flow cytometry analysis. |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
however, tnf inhibited wehi dna synthesis as early as 1 h after treatment, and inhibition was proportionate to sensitivity to tnf-induced apoptosis. |
1996-05-13 |
2023-08-12 |
Not clear |
| S C Shih, O Stutma. Cell cycle-dependent tumor necrosis factor apoptosis. Cancer research. vol 56. issue 7. 1996-05-13. PMID:8603407. |
these results show that tnf-induced apoptosis of wehi cells is connected to cell cycle events; wehi targets receive the tnf cytotoxic signal mainly at the g1-s boundary and begin to die by apoptosis as they exit from s phase. |
1996-05-13 |
2023-08-12 |
Not clear |
| M Verheij, R Bose, X H Lin, B Yao, W D Jarvis, S Grant, M J Birrer, E Szabo, L I Zon, J M Kyriakis, A Haimovitz-Friedman, Z Fuks, R N Kolesnic. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. vol 380. issue 6569. 1996-04-22. PMID:8598911. |
the sphingomyelin pathway, initiated by hydrolysis of the phospholipid sphingomyelin in the cell membrane to generate the second messenger ceramide, is thought to mediate apoptosis in response to tumour-necrosis factor (tnf)-alpha, to fas ligand and to x-rays. |
1996-04-22 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
here we report that tnf alpha mediates apoptosis in kc and sinusoidal endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
tnf alpha antibody blocked apoptosis in both kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
reducing transmembrane tnf alpha expressed on kc also led to a decrease in endothelial cell apoptosis, suggesting that transmembrane tnf alpha is implicated in the cell-to-cell contact mechanism of induction of apoptosis. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
thus, tnf alpha mediates apoptosis in kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| E S Bour, L K Ward, G A Cornman, H C Iso. Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term culture. The American journal of pathology. vol 148. issue 2. 1996-03-11. PMID:8579111. |
we demonstrated that treatment with tumor necrosis factor (tnf)-alpha induced apoptosis (detected morphologically and by formation of an oligonucleosomal dna ladder) only in hepatocytes that had been subjected to dimethylsulfoxide removal. |
1996-03-11 |
2023-08-12 |
rat |
| D J MacEwa. Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis. FEBS letters. vol 379. issue 1. 1996-03-06. PMID:8566235. |
elevated cpla2 levels as a mechanism by which the p70 tnf and p75 ngf receptors enhance apoptosis. |
1996-03-06 |
2023-08-12 |
Not clear |
| M Ido, K Hayashi, S Kato, H Ogawa, Y Komada, Y W Zhau, X L Zhang, M Sakurai, K Suzuk. Isolation and characterisation of Kasumi-1 human myeloid leukaemia cell line resistant to tumour necrosis factor alpha-induced apoptosis. British journal of cancer. vol 73. issue 3. 1996-03-05. PMID:8562342. |
tumour necrosis factor (tnf)-alpha induces apoptosis in a human acute myeloid leukaemia cell line, kasumi-1. |
1996-03-05 |
2023-08-12 |
human |
| H Hsu, H B Shu, M G Pan, D V Goedde. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. vol 84. issue 2. 1996-03-01. PMID:8565075. |
tumor necrosis factor (tnf) can induce apoptosis and activate nf-kappa b through signaling cascades emanating from tnf receptor 1 (tnfr1). |
1996-03-01 |
2023-08-12 |
Not clear |
| M Jäättelä, H Mouritzen, F Elling, L Basthol. A20 zinc finger protein inhibits TNF and IL-1 signaling. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8557994. |
overexpression of a20 in mcf7 breast carcinoma cells or in wehi-s fibrosarcoma cells inhibits apoptosis induced by tnf, whereas cytotoxicity induced by anti-fas (anti-cd95); lymphokine-activated killer (lak) cells, serum starvation, oxidative stress, or okadaic acid is not inhibited. |
1996-02-27 |
2023-08-12 |
Not clear |