| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Marsters, R M Pitti, C J Donahue, S Ruppert, K D Bauer, A Ashkenaz. Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. Current biology : CB. vol 6. issue 6. 1997-03-10. PMID:8793301. |
this finding suggests that, like fas/apo-1 ligand and tnf [3-5], apo-2l may play a role in regulating post-stimulation apoptosis of mature lymphocytes. |
1997-03-10 |
2023-08-12 |
Not clear |
| S A Marsters, R M Pitti, C J Donahue, S Ruppert, K D Bauer, A Ashkenaz. Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. Current biology : CB. vol 6. issue 6. 1997-03-10. PMID:8793301. |
ectopic expression of a dominant negative mutant of fadd, a cytoplasmic protein that mediates death signalling by fas/apo-1 and by tnf receptor type 1 (tnfr1) [6-9], inhibited the induction of apoptosis by anti-fas/apo-1 antibody, but had little effect on apo-2l function. |
1997-03-10 |
2023-08-12 |
Not clear |
| J Yui, D Hemmings, M Garcia-Lloret, L J Guilber. Expression of the human p55 and p75 tumor necrosis factor receptors in primary villous trophoblasts and their role in cytotoxic signal transduction. Biology of reproduction. vol 55. issue 2. 1997-03-10. PMID:8828846. |
since both p55 and p75 tnf receptors (tnfrs) localize to the villous trophoblast, we examined their roles in mediating trophoblast apoptosis. |
1997-03-10 |
2023-08-12 |
human |
| J Yui, D Hemmings, M Garcia-Lloret, L J Guilber. Expression of the human p55 and p75 tumor necrosis factor receptors in primary villous trophoblasts and their role in cytotoxic signal transduction. Biology of reproduction. vol 55. issue 2. 1997-03-10. PMID:8828846. |
agonistic anti-tnfrp55 antibody and tnfrp55-specific tnf mutant protein stimulated both apoptosis and loss of trophoblast viability. |
1997-03-10 |
2023-08-12 |
human |
| J Yui, D Hemmings, M Garcia-Lloret, L J Guilber. Expression of the human p55 and p75 tumor necrosis factor receptors in primary villous trophoblasts and their role in cytotoxic signal transduction. Biology of reproduction. vol 55. issue 2. 1997-03-10. PMID:8828846. |
furthermore, neither cell death nor apoptosis stimulated by wild-type tnf alpha was inhibited by an antagonistic anti-tnfrp75 antibody. |
1997-03-10 |
2023-08-12 |
human |
| D C Huang, S Cory, A Strasse. Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene. vol 14. issue 4. 1997-03-07. PMID:9053837. |
in contrast, none of them could effectively counter apoptosis induced via the tnf receptor or fas/apo-1 (cd95). |
1997-03-07 |
2023-08-12 |
Not clear |
| M Kameoka, T Kimura, Q Zhong, Y H Zheng, R B Luftig, K Ikut. Induction of apoptosis by protease-defective particle preparations of human immunodeficiency virus type 1 is specific to a subset of U937-derived subclones. International immunology. vol 8. issue 11. 1997-03-03. PMID:8943563. |
kinetic analysis revealed that there was a slower induction of apoptosis by l-2 particle preparations than with tumor necrosis factor (tnf)-alpha or anti-fas antibody. |
1997-03-03 |
2023-08-12 |
human |
| J R Ortaldo, R T Winkler-Pickett, S Nagata, C F War. Fas involvement in human NK cell apoptosis: lack of a requirement for CD16-mediated events. Journal of leukocyte biology. vol 61. issue 2. 1997-02-26. PMID:9021927. |
activation-induced apoptosis of t cells is mediated by members of the tumor necrosis factor (tnf) cytokine superfamily. |
1997-02-26 |
2023-08-12 |
human |
| A Flugy, N Borsellino, N D'Alessandr. TNF-induced apoptosis in multidrug resistant friend erythroleukemia is not influenced by the P-glycoprotein and glutathione status of the cell line. Oncology research. vol 7. issue 10-11. 1997-02-19. PMID:8866668. |
nonetheless, tnf caused even greater cytotoxicity and apoptosis, with no induction of differentiation markers, in flc-dxr. |
1997-02-19 |
2023-08-12 |
Not clear |
| K Takamuku, K Baba, S Arinaga, J Li, M Mori, T Akiyosh. Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: enhancement with interferon gamma. Cancer immunology, immunotherapy : CII. vol 43. issue 4. 1997-02-19. PMID:9003467. |
however, the release of tumor necrosis factor alpha (tnf alpha) was significantly enhanced during admc, while, in addition, apoptosis was significantly inhibited by the addition of anti-tnf alpha antibody. |
1997-02-19 |
2023-08-12 |
human |
| K Takamuku, K Baba, S Arinaga, J Li, M Mori, T Akiyosh. Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: enhancement with interferon gamma. Cancer immunology, immunotherapy : CII. vol 43. issue 4. 1997-02-19. PMID:9003467. |
these findings indicated that apoptosis might be implicated in admc with mab 17-1a, which was augmented by ifn gamma, while, in addition, tnf alpha may also be one of the major mediators of apoptosis. |
1997-02-19 |
2023-08-12 |
human |
| W Fiers, R Beyaert, E Boone, S Cornelis, W Declercq, E Decoster, G Denecker, B Depuydt, D De Valck, G De Wilde, V Goossens, J Grooten, G Haegeman, K Heyninck, L Penning, S Plaisance, K Vancompernolle, W Van Criekinge, P Vandenabeele, W Vanden Berghe, M Van de Craen, V Vandevoorde, D Vercamme. TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis. Journal of inflammation. vol 47. issue 1-2. 1997-02-14. PMID:8913931. |
tnf treatment of many other cell types results in apoptosis, and this process involves activation of one or more ice homologs (iho). |
1997-02-14 |
2023-08-12 |
mouse |
| R Datta, H Kojima, D Banach, N J Bump, R V Talanian, E S Alnemri, R R Weichselbaum, W W Wong, D W Kuf. Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. The Journal of biological chemistry. vol 272. issue 3. 1997-02-13. PMID:8999887. |
overexpression of the cowpox protein crma blocked tumor necrosis factor (tnf)-induced apoptosis but had no effect on ir-induced dna fragmentation or cleavage of poly(adp-ribose) polymerase and protein kinase c delta. |
1997-02-13 |
2023-08-12 |
Not clear |
| R Datta, H Kojima, D Banach, N J Bump, R V Talanian, E S Alnemri, R R Weichselbaum, W W Wong, D W Kuf. Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. The Journal of biological chemistry. vol 272. issue 3. 1997-02-13. PMID:8999887. |
these findings indicate that ir-induced apoptosis involves activation of cpp32 and that this crma-insensitive apoptotic pathway is distinct from those induced by tnf and certain other stimuli. |
1997-02-13 |
2023-08-12 |
Not clear |
| R U Jänicke, P A Walker, X Y Lin, A G Porte. Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. The EMBO journal. vol 15. issue 24. 1997-02-13. PMID:9003773. |
here we show that the c-terminal 42 amino acid peptide of the retinoblastoma (rb) protein, an important cell cycle regulator with a known anti-apoptotic function, is specifically cleaved off by an ice-like protease in tumour necrosis factor (tnf)- and staurosporine-induced apoptosis. |
1997-02-13 |
2023-08-12 |
Not clear |
| R H Lin, Y W Hwang, B C Yang, C S Li. TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 2. 1997-02-11. PMID:8992973. |
tnf receptor-2-triggered apoptosis is associated with the down-regulation of bcl-xl on activated t cells and can be prevented by cd28 costimulation. |
1997-02-11 |
2023-08-12 |
Not clear |
| A D Badley, D Dockrell, M Simpson, R Schut, D H Lynch, P Leibson, C V Pay. Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. The Journal of experimental medicine. vol 185. issue 1. 1997-02-07. PMID:8996241. |
additional analyses indicated that the apoptosis-inducing ligands, fasl and tumor necrosis factor (tnf), mediate this macrophage-induced apoptosis of cd4+ t cells. |
1997-02-07 |
2023-08-12 |
human |
| J K Lazdins, M Grell, M R Walker, K Woods-Cook, P Scheurich, K Pfizenmaie. Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells. The Journal of experimental medicine. vol 185. issue 1. 1997-02-07. PMID:8996244. |
more relevant, in vitro hiv-infected peripheral blood lymphocytes cocultured with cells expressing membrane tnf underwent rapid induction of apoptosis with a subsequent reduced hiv production of these lymphocytes cultures. |
1997-02-07 |
2023-08-12 |
Not clear |
| G Tiegs, F Gantne. Immunotoxicology of T cell-dependent experimental liver injury. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 48. issue 5. 1997-02-06. PMID:8765693. |
tumor necrosis factor-alpha (tnf) was identified as a common cytotoxic mediator which induced hepatocyte apoptosis as characterized by histological examination and internucleosomal dna fragmentation, that preceded the release of liver specific enzymes into plasma and the histological appearance of necrosis. |
1997-02-06 |
2023-08-12 |
Not clear |
| J E Castro, J A Listman, B A Jacobson, Y Wang, P A Lopez, S Ju, P W Finn, D L Perkin. Fas modulation of apoptosis during negative selection of thymocytes. Immunity. vol 5. issue 6. 1997-01-30. PMID:8986720. |
fas, a member of the tnf receptor family, has been shown to induce apoptosis in mature peripheral t cells; however, the effects of fas on negative selection of thymocytes have not been previously detected. |
1997-01-30 |
2023-08-12 |
mouse |