| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Lüschen, S Ussat, G Scherer, D Kabelitz, S Adam-Klage. Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression. The Journal of biological chemistry. vol 275. issue 32. 2000-09-14. PMID:10827087. |
here, we report that in nih3t3 cells, apoptosis in response tnf and cycloheximide is not inhibited by the broad spectrum caspase inhibitor benzyloxycarbonyl-val-ala-asp-fluoromethyl ketone (zvad. |
2000-09-14 |
2023-08-12 |
Not clear |
| H T Idriss, J H Naismit. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microscopy research and technique. vol 50. issue 3. 2000-08-31. PMID:10891884. |
tumour necrosis factor alpha (tnf alpha), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. |
2000-08-31 |
2023-08-12 |
Not clear |
| H T Idriss, J H Naismit. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microscopy research and technique. vol 50. issue 3. 2000-08-31. PMID:10891884. |
additionally, a number of structurally related "decoy receptors" exist that act to sequester tnf molecules, thereby rescuing cells from apoptosis. |
2000-08-31 |
2023-08-12 |
Not clear |
| B A Fischer, S Mundle, A A Col. Tumor necrosis factor-alpha induced DNA cleavage in human articular chondrocytes may involve multiple endonucleolytic activities during apoptosis. Microscopy research and technique. vol 50. issue 3. 2000-08-31. PMID:10891889. |
apoptosis was induced in the chondrocytes by either tumor necrosis factor alpha (tnf alpha), interleukin 1-beta (il-1 beta), or anti-fas antibody but only after 48 hours in culture. |
2000-08-31 |
2023-08-12 |
human |
| B A Fischer, S Mundle, A A Col. Tumor necrosis factor-alpha induced DNA cleavage in human articular chondrocytes may involve multiple endonucleolytic activities during apoptosis. Microscopy research and technique. vol 50. issue 3. 2000-08-31. PMID:10891889. |
when the chondrocytes were cultured as explants with the articular matrix intact (ex vivo), neither il-1 beta, tnf alpha, the anti-fas antibody, nor fibronectin fragments were able to induce apoptosis in the chondrocytes. |
2000-08-31 |
2023-08-12 |
human |
| N Mitsiades, V Poulaki, S Tseleni-Balafouta, D A Koutras, I Stamenkovi. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer research. vol 60. issue 15. 2000-08-31. PMID:10945619. |
fas (apo-1/cd95) is a transmembrane protein of the tumor necrosis factor (tnf)/nerve growth factor receptor superfamily that induces apoptosis in susceptible normal and neoplastic cells upon cross-linking by its ligand (fasl). |
2000-08-31 |
2023-08-12 |
Not clear |
| K Tokushige, N Yamaguchi, I Ikeda, E Hashimoto, K Yamauchi, N Hayash. Significance of soluble TNF receptor-I in acute-type fulminant hepatitis. The American journal of gastroenterology. vol 95. issue 8. 2000-08-30. PMID:10950055. |
fulminant hepatitis is associated with apoptosis of hepatocytes, which is mediated via fas and tumor necrosis factor (tnf) receptors. |
2000-08-30 |
2023-08-12 |
Not clear |
| M Rojas, L F García, J Nigou, G Puzo, M Olivie. Mannosylated lipoarabinomannan antagonizes Mycobacterium tuberculosis-induced macrophage apoptosis by altering Ca+2-dependent cell signaling. The Journal of infectious diseases. vol 182. issue 1. 2000-08-28. PMID:10882603. |
mycobacterium tuberculosis-induced macrophage apoptosis can be inhibited by mannosylated lipoarabinomannan (manlam), although it induces tumor necrosis factor (tnf)-alpha and no production, which participate in apoptosis induction. |
2000-08-28 |
2023-08-12 |
Not clear |
| S M Quirk, R M Harman, S C Huber, R G Cowa. Responsiveness of mouse corpora luteal cells to Fas antigen (CD95)-mediated apoptosis. Biology of reproduction. vol 63. issue 1. 2000-08-24. PMID:10859241. |
the effect of pretreatment of cultures with cytokines interferon gamma (ifn) and tumor necrosis factor alpha (tnf) was examined because these cytokines demonstrated effects on fas-mediated apoptosis in other cell types. |
2000-08-24 |
2023-08-12 |
mouse |
| K Streetz, L Leifeld, D Grundmann, J Ramakers, K Eckert, U Spengler, D Brenner, M Manns, C Trautwei. Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology. vol 119. issue 2. 2000-08-22. PMID:10930380. |
the tumor necrosis factor (tnf)-alpha/tnf receptor system is critical for liver development because hepatocytes undergo apoptosis if the antiapoptotic cascades resulting in rela nf-kappab activation are not effective. |
2000-08-22 |
2023-08-12 |
human |
| N Suarez-Huerta, R Mosselmans, J E Dumont, B Robay. Actin depolymerization and polymerization are required during apoptosis in endothelial cells. Journal of cellular physiology. vol 184. issue 2. 2000-08-17. PMID:10867649. |
in order to understand the role of actin microfilaments in the apoptotic process, we followed their evolution during tumor necrosis factor-alpha (tnf)-induced apoptosis in bovine aortic endothelial (bae) cells. |
2000-08-17 |
2023-08-12 |
cattle |
| N Suarez-Huerta, R Mosselmans, J E Dumont, B Robay. Actin depolymerization and polymerization are required during apoptosis in endothelial cells. Journal of cellular physiology. vol 184. issue 2. 2000-08-17. PMID:10867649. |
indeed, in the presence of cyochalasin, induction of apoptosis (internucleosomal dna degradation) in bae cells by tnf and cycloheximide was not associated with these classical morphological markers of apoptosis. |
2000-08-17 |
2023-08-12 |
cattle |
| J Golab, T Stoklosa, A Czajka, A Dabrowska, M Jakobisiak, R Zagozdzon, C Wojcik, M Marczak, S Wil. Synergistic antitumor effects of a selective proteasome inhibitor and TNF in mice. Anticancer research. vol 20. issue 3A. 2000-08-17. PMID:10928098. |
since this transcription factor is responsible for counteracting apoptosis induced by numerous agents, and proteasome inhibitors have already proved efficacious in increasing the proapoptotic activity of tnf in vitro, we decided to evaluate the antitumor effects of the combined psi and tnf treatment against a murine c-26 carcinoma. |
2000-08-17 |
2023-08-12 |
mouse |
| J A López-Guerrero, M Alonso, F Martín-Belmonte, L Carrasc. Poliovirus induces apoptosis in the human U937 promonocytic cell line. Virology. vol 272. issue 2. 2000-08-15. PMID:10873768. |
poliovirus-resistant u937 cells (pru) have been isolated that are resistant to apoptosis induced by poliovirus, but that undergo apoptosis after treatment with tnf plus cycloheximide. |
2000-08-15 |
2023-08-12 |
human |
| X Z Xia, J Treanor, G Senaldi, S D Khare, T Boone, M Kelley, L E Theill, A Colombero, I Solovyev, F Lee, S McCabe, R Elliott, K Miner, N Hawkins, J Guo, M Stolina, G Yu, J Wang, J Delaney, S Y Meng, W J Boyle, H Hs. TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation. The Journal of experimental medicine. vol 192. issue 1. 2000-08-15. PMID:10880535. |
we and others recently reported tumor necrosis factor (tnf) and apoptosis ligand-related leukocyte-expressed ligand 1 (tall-1) as a novel member of the tnf ligand family that is functionally involved in b cell proliferation. |
2000-08-15 |
2023-08-12 |
mouse |
| D C Mares, K M Heidler, G N Smith, O W Cummings, E R Harris, B Foresman, D S Wilke. Type V collagen modulates alloantigen-induced pathology and immunology in the lung. American journal of respiratory cell and molecular biology. vol 23. issue 1. 2000-08-14. PMID:10873154. |
we developed a murine model in which instillations of allogeneic bronchoalveolar lavage (bal) cells (c57bl/6, i-a(b), h-2(b)) into lungs of balb/c mice (i-a(d), h-2(d)) induce histology similar to grades 1 and 2 acute lung allograft rejection, apoptosis of airway epithelium and vascular endothelium, and upregulate tumor necrosis factor (tnf)-alpha production locally. |
2000-08-14 |
2023-08-12 |
mouse |
| J Xaus, M Comalada, A F Valledor, J Lloberas, F López-Soriano, J M Argilés, C Bogdan, A Celad. LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-alpha. Blood. vol 95. issue 12. 2000-08-10. PMID:10845916. |
in contrast, early apoptosis was paralleled by the rapid secretion of tnf and was almost absent in macrophages from mice deficient for one (p55) or both (p55 and p75) tnf-receptors. |
2000-08-10 |
2023-08-12 |
mouse |
| J Xaus, M Comalada, A F Valledor, J Lloberas, F López-Soriano, J M Argilés, C Bogdan, A Celad. LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-alpha. Blood. vol 95. issue 12. 2000-08-10. PMID:10845916. |
no-mediated cell death, but not apoptosis induced by tnf, correlated with the induction of p53 and bax genes. |
2000-08-10 |
2023-08-12 |
mouse |
| E Nisoli, L Briscini, A Giordano, C Tonello, S M Wiesbrock, K T Uysal, S Cinti, M O Carruba, G S Hotamisligi. Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 14. 2000-08-10. PMID:10884431. |
the absence of both tnf receptors or p55 receptor alone resulted in a significant reduction in brown adipocyte apoptosis and an increase in beta(3)-adrenoreceptor and uncoupling protein-1 expression in obese mice. |
2000-08-10 |
2023-08-12 |
mouse |
| E A Slee, S A Keogh, S J Marti. Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release. Cell death and differentiation. vol 7. issue 6. 2000-08-08. PMID:10822279. |
bid, a pro-apoptotic bcl-2 family member, promotes cytochrome c release during apoptosis initiated by cd95l or tnf. |
2000-08-08 |
2023-08-12 |
Not clear |