| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G S Filippatos, K Tsilias, K Venetsanou, E Karambinos, D Manolatos, A Kranidis, J Antonellis, F Kardaras, L Anthopoulos, G Baltopoulo. Leptin serum levels in cachectic heart failure patients. Relationship with tumor necrosis factor-alpha system. International journal of cardiology. vol 76. issue 2-3. 2001-03-08. PMID:11104865. |
to investigate the role of leptin and regulators of apoptosis in cardiac cachexia we compared leptin concentrations and their relation to the tnf system, interleukin 1-beta (il-1b), and soluble fas in patients with heart failure with and without cachexia. |
2001-03-08 |
2023-08-12 |
Not clear |
| M Pelagi, F Curnis, B Colombo, P Rovere, A Sacchi, A A Manfredi, A Cort. Caspase inhibition reveals functional cooperation between p55- and p75-TNF receptors in cell necrosis. European cytokine network. vol 11. issue 4. 2001-03-08. PMID:11125300. |
cytometric analysis after tnf treatment showed that apoptosis was inhibited, while necrosis was highly activated. |
2001-03-08 |
2023-08-12 |
mouse |
| M Pelagi, F Curnis, B Colombo, P Rovere, A Sacchi, A A Manfredi, A Cort. Caspase inhibition reveals functional cooperation between p55- and p75-TNF receptors in cell necrosis. European cytokine network. vol 11. issue 4. 2001-03-08. PMID:11125300. |
in contrast, apoptosis was observed in cells treated with tnf and actinomycin d alone. |
2001-03-08 |
2023-08-12 |
mouse |
| M Pelagi, F Curnis, B Colombo, P Rovere, A Sacchi, A A Manfredi, A Cort. Caspase inhibition reveals functional cooperation between p55- and p75-TNF receptors in cell necrosis. European cytokine network. vol 11. issue 4. 2001-03-08. PMID:11125300. |
stimulation of tnfr1 was sufficient to induce either cell necrosis or apoptosis, even when we blocked endogenous tnf with an anti-murine tnf antibody. |
2001-03-08 |
2023-08-12 |
mouse |
| B N Ditte. Evidence that Fas and FasL contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Archivum immunologiae et therapiae experimentalis. vol 48. issue 5. 2001-03-08. PMID:11140465. |
tnf-alpha and lt-alpha are both members of the tnf family of molecules and cause cell death by apoptosis following interaction with their counter-receptors, the tnfr1 and tnfr2, leading to a cascade of proteolytic events culminating in the blebbing of the cytoplasmic membrane, nuclear condensation and dna fragmentation. |
2001-03-08 |
2023-08-12 |
mouse |
| K Suzuki, T Hasegawa, C Sakamoto, Y M Zhou, F Hato, M Hino, N Tatsumi, S Kitagaw. Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: role in decreased responsiveness to inflammatory cytokines. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 2. 2001-03-08. PMID:11145700. |
both molecules were cleaved at the n-terminal portion in neutrophils undergoing apoptosis induced by in vitro culture alone or treatment with tnf and/or cycloheximide. |
2001-03-08 |
2023-08-12 |
human |
| F Ozawa, H Friess, J Kleeff, Z W Xu, A Zimmermann, M S Sheikh, M W Büchle. Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer. Cancer letters. vol 163. issue 1. 2001-03-08. PMID:11163110. |
pancreatic cancer cells are usually resistant to apoptosis mediated by tumor necrosis factor (tnf)-alpha or fasl, and their toxicity towards normal cells hampers their application for therapeutic use. |
2001-03-08 |
2023-08-12 |
human |
| F Ozawa, H Friess, J Kleeff, Z W Xu, A Zimmermann, M S Sheikh, M W Büchle. Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer. Cancer letters. vol 163. issue 1. 2001-03-08. PMID:11163110. |
tnf-related apoptosis-inducing ligand (trail), a novel member of the tnf family, triggers apoptosis in a variety of malignant cells, but exhibits less cytotoxicity in normal cells. |
2001-03-08 |
2023-08-12 |
human |
| E J Kim, A Suliman, A Lam, R K Srivastav. Failure of Bcl-2 to block mitochondrial dysfunction during TRAIL-induced apoptosis. Tumor necrosis-related apoptosis-inducing ligand. International journal of oncology. vol 18. issue 1. 2001-02-15. PMID:11115558. |
tumor necrosis (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf family of cytokines that promotes apoptosis. |
2001-02-15 |
2023-08-12 |
Not clear |
| K Clodi, D Wimmer, Y Li, R Goodwin, U Jaeger, G Mann, H Gadner, A Youne. Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells. British journal of haematology. vol 111. issue 2. 2001-02-15. PMID:11122106. |
expression of tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) receptors and sensitivity to trail-induced apoptosis in primary b-cell acute lymphoblastic leukaemia cells. |
2001-02-15 |
2023-08-12 |
Not clear |
| Y L Wu, X R Jiang, D M Lillington, A C Newland, S M Kelse. Upregulation of lipocortin 1 inhibits tumour necrosis factor-induced apoptosis in human leukaemic cells: a possible mechanism of resistance to immune surveillance. British journal of haematology. vol 111. issue 3. 2001-02-15. PMID:11122142. |
the signal transduction pathway through which tumour necrosis factor (tnf) induces apoptosis in leukaemic cells may involve activation of cytosolic phospholipase a(2) (cpla(2)). |
2001-02-15 |
2023-08-12 |
human |
| Y L Wu, X R Jiang, D M Lillington, A C Newland, S M Kelse. Upregulation of lipocortin 1 inhibits tumour necrosis factor-induced apoptosis in human leukaemic cells: a possible mechanism of resistance to immune surveillance. British journal of haematology. vol 111. issue 3. 2001-02-15. PMID:11122142. |
our data suggest that dex confers the resistance of u937 cells to tnf-induced apoptosis by upregulating intracellular levels of lc1 and by facilitating a negative-feedback loop, which is activated upon stimulation with tnf. |
2001-02-15 |
2023-08-12 |
human |
| D Kobayashi, N Watanabe, N Yamauchi, T Okamoto, N Tsuji, H Sasaki, T Sato, Y Niits. Heat-induced apoptosis via caspase-3 activation in tumour cells carrying mutant p53. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. vol 16. issue 6. 2001-02-08. PMID:11129259. |
in the present study, the signal transduction pathway underlying heat-induced apoptosis was investigated in heat-resistant hela cells carrying mutant p53 gene and heat sensitive hela cells that had been transduced with an antisense tnf gene. |
2001-02-08 |
2023-08-12 |
Not clear |
| S C Hasmall, D A West, K Olsen, R A Robert. Role of hepatic non-parenchymal cells in the response of rat hepatocytes to the peroxisome proliferator nafenopin in vitro. Carcinogenesis. vol 21. issue 12. 2001-02-08. PMID:11133804. |
removal of non-parenchymal cells from normal hepatocyte cultures prevented both the nafenopin- and tnf alpha-induced increase in dna synthesis and suppression of hepatocyte apoptosis; this response was restored by returning non-parenchymal cells to the purified hepatocytes. |
2001-02-08 |
2023-08-12 |
rat |
| S Aggarwal, S Gollapudi, L Yel, A S Gupta, S Gupt. TNF-alpha-induced apoptosis in neonatal lymphocytes: TNFRp55 expression and downstream pathways of apoptosis. Genes and immunity. vol 1. issue 4. 2001-02-08. PMID:11196704. |
in this study, we compared tumor necrosis factor (tnf)-alpha-induced apoptosis in t lymphocytes and their subsets between cord blood and peripheral blood from healthy young controls. |
2001-02-08 |
2023-08-12 |
Not clear |
| S K Manna, V Haridas, B B Aggarwa. Bcl-x(L) suppresses TNF-mediated apoptosis and activation of nuclear factor-kappaB, activation protein-1, and c-Jun N-terminal kinase. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 8. 2001-02-02. PMID:10954916. |
tumor necrosis factor (tnf) is a multipotential cytokine that induces apoptosis and activates nuclear factor-kappa b (nf-kappab), activation protein 1 (ap-1), mitogen-activated protein kinase (mapk), and c-jun n-terminal kinase (jnk). |
2001-02-02 |
2023-08-12 |
human |
| S K Manna, V Haridas, B B Aggarwa. Bcl-x(L) suppresses TNF-mediated apoptosis and activation of nuclear factor-kappaB, activation protein-1, and c-Jun N-terminal kinase. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 8. 2001-02-02. PMID:10954916. |
overall, our results demonstrate that bcl-x(l) inhibits tnf signaling at an early step common to induction of activation of apoptosis, nf-kappab, ap-1, mapk, and jnk. |
2001-02-02 |
2023-08-12 |
human |
| T Nguyen, W Thomas, X D Zhang, C Gray, P Herse. Immunologically-mediated tumour cell apoptosis: the role of TRAIL in T cell and cytokine-mediated responses to melanoma. Forum (Genoa, Italy). vol 10. issue 3. 2001-02-02. PMID:11007932. |
our studies have shown that cd4 t cells appear to kill melanoma by means of a member of the tumour necrosis factor (tnf) family expressed on their surface and called tnf related apoptosis inducing ligand (trail). |
2001-02-02 |
2023-08-12 |
human |
| A Eggert, H Sieverts, N Ikegaki, G M Brodeu. p75 mediated apoptosis in neuroblastoma cells is inhibited by expression of TrkA. Medical and pediatric oncology. vol 35. issue 6. 2001-02-02. PMID:11107120. |
the p75 receptor belongs to the tumor necrosis factor (tnf) family of death receptors and has been suggested as a receptor that mediates apoptosis in neuronal and nb cells. |
2001-02-02 |
2023-08-12 |
Not clear |
| F Zhu, W Yan, Z L Zhao, Y B Chai, F Lu, Q Wang, W D Peng, A G Yang, C J Wan. Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes. BioTechniques. vol 29. issue 2. 2001-02-01. PMID:10948432. |
apr-1, apr-2, apr-3 and tnf were reidentified by reverse dot blot, and it is suggested that they might be related to apoptosis. |
2001-02-01 |
2023-08-12 |
human |