| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Sträter, P Mölle. Expression and function of death receptors and their natural ligands in the intestine. Annals of the New York Academy of Sciences. vol 915. 2001-02-01. PMID:11193573. |
a more recently described member of the tnf family is trail, which is also able to induce apoptosis. |
2001-02-01 |
2023-08-12 |
Not clear |
| A Friedman, S Weiss, N Levy, R Meida. Role of tumor necrosis factor alpha and its type I receptor in luteal regression: induction of programmed cell death in bovine corpus luteum-derived endothelial cells. Biology of reproduction. vol 63. issue 6. 2001-01-26. PMID:11090464. |
in conclusion, this study suggests that tnf alpha-induced pcd during structural luteolysis is mediated by tnfri, primarily affects endothelial cells, and that the decline in progesterone, preceding structural luteolysis, is a prerequisite for the initiation of apoptosis in endothelial cells. |
2001-01-26 |
2023-08-12 |
cattle |
| F Diaz, L Y Bourguigno. Selective down-regulation of IP(3)receptor subtypes by caspases and calpain during TNF alpha -induced apoptosis of human T-lymphoma cells. Cell calcium. vol 27. issue 6. 2001-01-18. PMID:11013462. |
selective down-regulation of ip(3)receptor subtypes by caspases and calpain during tnf alpha -induced apoptosis of human t-lymphoma cells. |
2001-01-18 |
2023-08-12 |
human |
| V Maguer-Satta, R Oostendorp, D Reid, C J Eave. Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates. Blood. vol 96. issue 13. 2001-01-18. PMID:11110682. |
these findings indicate that tnf can directly modulate the ability of cd34(+)cd38(-) cells to maintain their ltc-ic function at doses below those required to initiate apoptosis, cell cycle arrest, or both, and they suggest that this may be mediated by the tnf-induced generation of intracellular ceramide. |
2001-01-18 |
2023-08-12 |
human |
| U Mahlknecht, C Deng, M C Lu, T C Greenough, J L Sullivan, W A O'Brien, G Herbei. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086083. |
tnf-alpha (tnf) expressed on the surface of macrophages prevented apoptosis in nef-expressing, productively infected cd4(+) t lymphocytes. |
2001-01-11 |
2023-08-12 |
Not clear |
| U Mahlknecht, C Deng, M C Lu, T C Greenough, J L Sullivan, W A O'Brien, G Herbei. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086083. |
similarly, following tnf stimulation, apoptosis was diminished in jurkat t cells transfected with a nef-expressing plasmid. |
2001-01-11 |
2023-08-12 |
Not clear |
| M Nagaki, T Naiki, D A Brenner, Y Osawa, M Imose, H Hayashi, Y Banno, S Nakashima, H Moriwak. Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kappaB. Hepatology (Baltimore, Md.). vol 32. issue 6. 2001-01-04. PMID:11093734. |
tumor necrosis factor alpha (tnf-alpha) binding to the tnf receptor (tnfr) initiates apoptosis and simultaneously activates the transcription factor, nuclear factor-kappab (nf-kappab), which suppresses apoptosis by an unknown mechanism. |
2001-01-04 |
2023-08-12 |
mouse |
| A Schulz, G Baue. Selective effect of tumor necrosis factor on transformed versus nontransformed cells: nonselective signal recognition but differential target cell response. Anticancer research. vol 20. issue 5B. 2001-01-04. PMID:11131645. |
in contrast, in nontransformed cells, due to their higher initial concentration of endogenous survival factors, down-modulation by tnf is not complete and therefore apoptosis is still prevented. |
2001-01-04 |
2023-08-12 |
Not clear |
| S Bang, E J Jeong, I K Kim, Y K Jung, K S Ki. Fas- and tumor necrosis factor-mediated apoptosis uses the same binding surface of FADD to trigger signal transduction. A typical model for convergent signal transduction. The Journal of biological chemistry. vol 275. issue 46. 2000-12-29. PMID:10952991. |
fadd is known to function as a common signaling conduit in fas- and tumor necrosis factor (tnf)-mediated apoptosis. |
2000-12-29 |
2023-08-12 |
Not clear |
| A Kaptein, M Jansen, G Dilaver, J Kitson, L Dash, E Wang, M J Owen, J L Bodmer, J Tschopp, S N Farro. Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3). FEBS letters. vol 485. issue 2-3. 2000-12-28. PMID:11094155. |
wsl-1/tramp (dr3) is a member of the tumour necrosis factor (tnf) receptor superfamily which exhibits effects on nf-kappab activation and apoptosis. |
2000-12-28 |
2023-08-12 |
mouse |
| J G Baseta, O Stutma. TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067918. |
tnf regulates thymocyte production by apoptosis and proliferation of the triple negative (cd3-cd4-cd8-) subset. |
2000-12-22 |
2023-08-12 |
mouse |
| J G Baseta, O Stutma. TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067918. |
our studies showed that tnf regulates mouse thymocyte production, inducing both apoptosis and proliferation of the most immature cd3(-)cd4(-)cd8(-) triple negative (tn) subset within a broad range of dosages (10(1)-10(5) pg/ml) in the presence of il-7. |
2000-12-22 |
2023-08-12 |
mouse |
| J G Baseta, O Stutma. TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067918. |
tnf apoptosis affected only the tn3 (cd44(-)cd25(+)) and tn4 (cd44(-)cd25(-)) subsets that expressed both tnfr-p55 and -p75. |
2000-12-22 |
2023-08-12 |
mouse |
| J G Baseta, O Stutma. TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067918. |
although each tnfr alone could mediate tnf apoptosis, maximal apoptosis was seen in c57bl/6j wild type, which expressed both tnfrs. |
2000-12-22 |
2023-08-12 |
mouse |
| R Rückert, G Lindner, S Bulfone-Paus, R Pau. High-dose proinflammatory cytokines induce apoptosis of hair bulb keratinocytes in vivo. The British journal of dermatology. vol 143. issue 5. 2000-12-08. PMID:11069516. |
while the effects of different cytokines or other apoptosis stimulating agents such as interferon (ifn)-gamma or tumour necrosis factor (tnf)-alpha on kc apoptosis in vitro have been addressed in several studies, little is known about the effects of proinflammatory cytokines on kc apoptosis in vivo. |
2000-12-08 |
2023-08-12 |
Not clear |
| O Janssen, R Sanzenbacher, D Kabelit. Regulation of activation-induced cell death of mature T-lymphocyte populations. Cell and tissue research. vol 301. issue 1. 2000-12-07. PMID:10928283. |
t-cell apoptosis and aicd are controlled by survival cytokines such as interleukin-2 (il-2) and by death factors such as tumor necrosis factor (tnf) and cd95 ligand (cd95l). |
2000-12-07 |
2023-08-12 |
Not clear |
| T Kita, T Tanaka, N Tanaka, Y Kinoshit. The role of tumor necrosis factor-alpha in diffuse axonal injury following fluid-percussive brain injury in rats. International journal of legal medicine. vol 113. issue 4. 2000-12-07. PMID:10929238. |
it is generally accepted that tnf alpha directly induces primary demyelination and oligodendrocyte apoptosis. |
2000-12-07 |
2023-08-12 |
rat |
| F F Palazzo, L J Hammond, A W Goode, R Mirakia. Death of the autoimmune thyrocyte: is it pushed or does it jump? Thyroid : official journal of the American Thyroid Association. vol 10. issue 7. 2000-12-07. PMID:10958308. |
the mechanism of apoptosis is under the control of antiapoptotic survival genes of the bcl-2 family and proapoptotic death receptors of the tnf superfamily (fas, tnfr, trailr). |
2000-12-07 |
2023-08-12 |
Not clear |
| Y B Lee, T Y Yune, S Y Baik, Y H Shin, S Du, H Rhim, E B Lee, Y C Kim, M L Shin, G J Markelonis, T H O. Role of tumor necrosis factor-alpha in neuronal and glial apoptosis after spinal cord injury. Experimental neurology. vol 166. issue 1. 2000-12-07. PMID:11031095. |
we investigated the role of tumor necrosis factor (tnf)-alpha in the onset of neuronal and glial apoptosis after traumatic spinal cord crush injury in rats. |
2000-12-07 |
2023-08-12 |
rat |
| J O Funk, H Walczak, C Voigtländer, S Berchtold, T Baumeister, P Rauch, S Rössner, A Steinkasserer, G Schuler, M B Lut. Cutting edge: resistance to apoptosis and continuous proliferation of dendritic cells deficient for TNF receptor-1. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 9. 2000-11-30. PMID:11046001. |
cutting edge: resistance to apoptosis and continuous proliferation of dendritic cells deficient for tnf receptor-1. |
2000-11-30 |
2023-08-12 |
mouse |