| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Bernard, C Slomianny, B Vandenbunder, C Abbadi. cRel induces mitochondrial alterations in correlation with proliferation arrest. Free radical biology & medicine. vol 31. issue 8. 2002-01-10. PMID:11595379. |
altogether, our findings show that crel overexpression in hela cells creates, via the induction of mnsod, an oxidative injury that culminates in mitochondrial degeneration, proliferation blockage, and resistance against tnf alpha-induced apoptosis. |
2002-01-10 |
2023-08-12 |
Not clear |
| F Yan, S K John, D B Pol. Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor. Cancer research. vol 61. issue 24. 2002-01-10. PMID:11751383. |
a central cytokine in the pathogenesis of inflammatory bowel disease is tumor necrosis factor (tnf), which increases apoptosis in a number of cell types. |
2002-01-10 |
2023-08-12 |
mouse |
| F Yan, S K John, D B Pol. Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor. Cancer research. vol 61. issue 24. 2002-01-10. PMID:11751383. |
furthermore, inhibitors of both erk and nuclear factor kappa b activation synergistically enhance apoptosis of cells treated with tnf. |
2002-01-10 |
2023-08-12 |
mouse |
| G M Kasof, J J Lu, D Liu, B Speer, K N Mongan, B C Gomes, M V Lorenz. Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. Oncogene. vol 20. issue 55. 2002-01-10. PMID:11753679. |
the tumor necrosis factor (tnf) receptor family are ligand-regulated transmembrane proteins that mediate apoptosis as well as activation of the transcription factor nf-kappab. |
2002-01-10 |
2023-08-12 |
Not clear |
| G M Kasof, J J Lu, D Liu, B Speer, K N Mongan, B C Gomes, M V Lorenz. Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. Oncogene. vol 20. issue 55. 2002-01-10. PMID:11753679. |
exogenous expression of dr6, a recently identified member of the tnf receptor family, induced apoptosis in untransformed or tumor-derived cells and the apoptotic function of dr6 was inhibited by co-expression of bcl-2, bcl-x(l) or the inhibitor-of-apoptosis (iap) family member, survivin. |
2002-01-10 |
2023-08-12 |
Not clear |
| A Niemann-Jönsson, M P Ares, Z Q Yan, D X Bu, G N Fredrikson, L Brånén, I Pörn-Ares, A H Nilsson, J Nilsso. Increased rate of apoptosis in intimal arterial smooth muscle cells through endogenous activation of TNF receptors. Arteriosclerosis, thrombosis, and vascular biology. vol 21. issue 12. 2002-01-03. PMID:11742863. |
increased rate of apoptosis in intimal arterial smooth muscle cells through endogenous activation of tnf receptors. |
2002-01-03 |
2023-08-12 |
human |
| A Niemann-Jönsson, M P Ares, Z Q Yan, D X Bu, G N Fredrikson, L Brånén, I Pörn-Ares, A H Nilsson, J Nilsso. Increased rate of apoptosis in intimal arterial smooth muscle cells through endogenous activation of TNF receptors. Arteriosclerosis, thrombosis, and vascular biology. vol 21. issue 12. 2002-01-03. PMID:11742863. |
tumor necrosis factor-alpha (tnf-alpha) has been reported to stimulate growth of cultured human smcs, but activation of tnf receptors is also known to induce cell death by apoptosis. |
2002-01-03 |
2023-08-12 |
human |
| A Niemann-Jönsson, M P Ares, Z Q Yan, D X Bu, G N Fredrikson, L Brånén, I Pörn-Ares, A H Nilsson, J Nilsso. Increased rate of apoptosis in intimal arterial smooth muscle cells through endogenous activation of TNF receptors. Arteriosclerosis, thrombosis, and vascular biology. vol 21. issue 12. 2002-01-03. PMID:11742863. |
cytokine-induced apoptosis in intimal cells was effectively inhibited by treatment with antibodies against tnf receptors. |
2002-01-03 |
2023-08-12 |
human |
| A F McGettrick, R C Barnes, D M Worral. SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target. European journal of biochemistry. vol 268. issue 22. 2001-12-31. PMID:11722574. |
in this study we demonstrate the ability of scca2 to inhibit tumor necrosis factor-alpha (tnf alpha)-induced apoptosis. |
2001-12-31 |
2023-08-12 |
Not clear |
| A F McGettrick, R C Barnes, D M Worral. SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target. European journal of biochemistry. vol 268. issue 22. 2001-12-31. PMID:11722574. |
we investigated if the reactive centre loop (rcl) was necessary to allow scca2 to inhibit tnf alpha-mediated apoptosis. |
2001-12-31 |
2023-08-12 |
Not clear |
| A F McGettrick, R C Barnes, D M Worral. SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target. European journal of biochemistry. vol 268. issue 22. 2001-12-31. PMID:11722574. |
the rcl amino acids (e353q, l354g, s355a), flanking the predicted cleavage site, were mutated and the resulting scca2 lost both the ability to inhibit cathepsin g and to protect stably transfected cells from tnf alpha-induced apoptosis. |
2001-12-31 |
2023-08-12 |
Not clear |
| J M Hock, V Krishnan, J E Onyia, J P Bidwell, J Milas, D Stanislau. Osteoblast apoptosis and bone turnover. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 6. 2001-12-20. PMID:11393794. |
apoptosis may be triggered either by activation events that target mitochondria or endoplasmic reticulum or by activation of cell surface "death receptors," for example, those in the tumor necrosis factor (tnf) superfamily. |
2001-12-20 |
2023-08-12 |
Not clear |
| J M Hock, V Krishnan, J E Onyia, J P Bidwell, J Milas, D Stanislau. Osteoblast apoptosis and bone turnover. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 6. 2001-12-20. PMID:11393794. |
in reviewing factors regulating apoptosis in the postnatal skeleton, we discuss roles of cytokines, growth factors, members of the tnf pathway, and the extracellular matrix (ecm). |
2001-12-20 |
2023-08-12 |
Not clear |
| E De Smaele, F Zazzeroni, S Papa, D U Nguyen, R Jin, J Jones, R Cong, G Franzos. Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. Nature. vol 414. issue 6861. 2001-12-20. PMID:11713530. |
activation of nf-kappab antagonizes apoptosis or programmed cell death by numerous triggers, including the ligand engagement of 'death receptors' such as tumour-necrosis factor (tnf) receptor. |
2001-12-20 |
2023-08-12 |
Not clear |
| H Akari, S Bour, S Kao, A Adachi, K Strebe. The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors. The Journal of experimental medicine. vol 194. issue 9. 2001-12-18. PMID:11696595. |
the involvement of nf-kappab in vpu-induced apoptosis is further supported by the finding that the levels of antiapoptotic factors bcl-xl, a1/bfl-1, and tnf receptor-associated factor (traf)1, all of which are expressed in an nf-kappab-dependent manner, are reduced and, at the same time, levels of active caspase-3 are elevated. |
2001-12-18 |
2023-08-12 |
human |
| S Erlich, Y Goldshmit, Z Lupowitz, R Pinkas-Kramarsk. ErbB-4 activation inhibits apoptosis in PC12 cells. Neuroscience. vol 107. issue 2. 2001-12-17. PMID:11731109. |
in the present study we demonstrate that in the pc12-erbb-4 cells, neuregulin rescues cells from apoptosis induced by serum deprivation or tumor necrosis factor (tnf)alpha treatment. |
2001-12-17 |
2023-08-12 |
Not clear |
| S Erlich, Y Goldshmit, Z Lupowitz, R Pinkas-Kramarsk. ErbB-4 activation inhibits apoptosis in PC12 cells. Neuroscience. vol 107. issue 2. 2001-12-17. PMID:11731109. |
both neuregulin and ngf protect cells from apoptosis induced by serum deprivation and tnf alpha treatment. |
2001-12-17 |
2023-08-12 |
Not clear |
| E Nisoli, L Regianini, A Bulbarelli, L Briscini, R Bracale, R Breacale, M O Carrub. Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: role of nitric oxide-induced heat shock protein 70 expression. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25. issue 10. 2001-12-13. PMID:11673761. |
to elucidate the effects and molecular mechanism(s) by means of which noradrenaline (na) protects against the tumor necrosis factor (tnf)-alpha-induced apoptosis of brown adipocytes. |
2001-12-13 |
2023-08-12 |
rat |
| B D Elzey, T S Griffith, J M Herndon, R Barreiro, J Tschopp, T A Ferguso. Regulation of Fas ligand-induced apoptosis by TNF. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 6. 2001-12-12. PMID:11544288. |
regulation of fas ligand-induced apoptosis by tnf. |
2001-12-12 |
2023-08-12 |
mouse |
| B D Elzey, T S Griffith, J M Herndon, R Barreiro, J Tschopp, T A Ferguso. Regulation of Fas ligand-induced apoptosis by TNF. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 6. 2001-12-12. PMID:11544288. |
tnf levels rapidly increased in the eye after the injection of lymphoid cells, and these cells underwent apoptosis within 24 h. coinjection of anti-tnf ab with the lymphoid cells blocked this cell death. |
2001-12-12 |
2023-08-12 |
mouse |