| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B D Elzey, T S Griffith, J M Herndon, R Barreiro, J Tschopp, T A Ferguso. Regulation of Fas ligand-induced apoptosis by TNF. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 6. 2001-12-12. PMID:11544288. |
in vitro, tnf enhanced the fas-mediated apoptosis of unactivated t cells through decreased intracellular levels of flip and increased production of the pro-apoptotic molecule bax. |
2001-12-12 |
2023-08-12 |
mouse |
| B D Elzey, T S Griffith, J M Herndon, R Barreiro, J Tschopp, T A Ferguso. Regulation of Fas ligand-induced apoptosis by TNF. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 6. 2001-12-12. PMID:11544288. |
collectively, our results provide evidence of a role for the p75 tnfr in cell death in that tnf signaling through tnfr2 sensitizes lymphoid cells for fas-mediated apoptosis. |
2001-12-12 |
2023-08-12 |
mouse |
| Y Jin, E K Blue, S Dixon, L Hou, R B Wysolmerski, P J Gallaghe. Identification of a new form of death-associated protein kinase that promotes cell survival. The Journal of biological chemistry. vol 276. issue 43. 2001-12-07. PMID:11485996. |
overexpression of dapk-alpha, the mouse homolog of human dapk has a negligible effect on tumor necrosis factor (tnf)-induced apoptosis. |
2001-12-07 |
2023-08-12 |
mouse |
| B Wielockx, K Lannoy, S D Shapiro, T Itoh, S Itohara, J Vandekerckhove, C Liber. Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. Nature medicine. vol 7. issue 11. 2001-12-07. PMID:11689884. |
in a mouse model of lethal hepatitis induced by tnf, apoptosis and necrosis of hepatocytes, but also lethality, hypothermia and influx of leukocytes into the liver, are prevented by a broad-spectrum matrix metalloproteinase (mmp) inhibitor, bb-94. |
2001-12-07 |
2023-08-12 |
mouse |
| M Saio, S Radoja, M Marino, A B Fre. Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 10. 2001-12-07. PMID:11698429. |
tumor-infiltrating macrophages induce apoptosis in activated cd8(+) t cells by a mechanism requiring cell contact and mediated by both the cell-associated form of tnf and nitric oxide. |
2001-12-07 |
2023-08-12 |
mouse |
| Y C Yang, T Y Hsu, J Y Chen, C S Yang, R H Li. Tumour necrosis factor-alpha-induced apoptosis in cord blood T lymphocytes: involvement of both tumour necrosis factor receptor types 1 and 2. British journal of haematology. vol 115. issue 2. 2001-12-07. PMID:11703347. |
in the current investigation, we determined the capacity of tumour necrosis factor-alpha (tnf-alpha) to induce apoptosis in human naïve t cells in cord blood, and assessed the roles of two distinct tnf receptors (tnfrs) in mediating death signals. |
2001-12-07 |
2023-08-12 |
human |
| I W Park, C K Ullrich, E Schoenberger, R K Ganju, J E Groopma. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 5. 2001-12-05. PMID:11509621. |
this apoptosis occurred without induction of either fas or tnf, known mediators of programmed cell death. |
2001-12-05 |
2023-08-12 |
human |
| I W Park, C K Ullrich, E Schoenberger, R K Ganju, J E Groopma. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 5. 2001-12-05. PMID:11509621. |
taken together, these data demonstrate that hiv-1 tat is able to activate apoptosis in microvascular endothelium by a mechanism distinct from tnf secretion or the fas pathway. |
2001-12-05 |
2023-08-12 |
human |
| S C Afford, J Ahmed-Choudhury, S Randhawa, C Russell, J Youster, H A Crosby, A Eliopoulos, S G Hubscher, L S Young, D H Adam. CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 13. 2001-12-05. PMID:11689460. |
increased functional nf-kappab was seen early after cd40 ligation, but returned to baseline levels after 4 h. in contrast, the rapid up-regulation of ap-1 was sustained over 24 h. this study provides further functional evidence of the ability of cd40 to induce fas/fasl-dependent apoptosis of liver epithelial cells supporting the importance of cross-talk between tumor necrosis factor (tnf) receptor family members as an amplification step in apoptosis induction. |
2001-12-05 |
2023-08-12 |
human |
| D T Graves, M Oskoui, S Volejnikova, G Naguib, S Cai, T Desta, A Kakouras, Y Jian. Tumor necrosis factor modulates fibroblast apoptosis, PMN recruitment, and osteoclast formation in response to P. gingivalis infection. Journal of dental research. vol 80. issue 10. 2001-12-05. PMID:11706944. |
furthermore, this may represent a more general mechanism by which bacterial challenge induces apoptosis of matrix-producing cells through the induction of tnf. |
2001-12-05 |
2023-08-12 |
mouse |
| M Nagane, H J Huang, W K Cavene. The potential of TRAIL for cancer chemotherapy. Apoptosis : an international journal on programmed cell death. vol 6. issue 3. 2001-12-04. PMID:11388668. |
trail (tumor necrosis factor (tnf)-related apoptosis inducing ligand), a recently identified member of the growing tnf superfamily, binds to its cognate "death" receptors dr4 and dr5 as well as "decoy" receptors dcr1 and dcr2. |
2001-12-04 |
2023-08-12 |
mouse |
| K Oshima, N Yanase, C Ibukiyama, A Yamashina, N Kayagaki, H Yagita, J Mizuguch. Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells. Cytokine. vol 14. issue 4. 2001-12-04. PMID:11448118. |
apoptosis is induced by members of the tumour necrosis factor (tnf) family, including fas (cd95) and tnf-related apoptosis-inducing ligand (trail). |
2001-12-04 |
2023-08-12 |
Not clear |
| F L Bellisarii, S Gallina, R De Caterin. Tumor necrosis factor-alpha and cardiovascular diseases. Italian heart journal : official journal of the Italian Federation of Cardiology. vol 2. issue 6. 2001-12-04. PMID:11453575. |
tumor necrosis factor (tnf)-alpha is a potent inducible cytokine with pleiotropic biological effects, now implicated as a mediator of various physiologic and pathophysiologic events including inflammation, cell survival, growth, differentiation and apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| A H Boulares, A J Zoltoski, A Yakovlev, M Xu, M E Smulso. Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis. The Journal of biological chemistry. vol 276. issue 41. 2001-12-04. PMID:11461900. |
dff45 deficiency rendered fibroblasts resistant to apoptosis induced by tumor necrosis factor (tnf). |
2001-12-04 |
2023-08-12 |
mouse |
| Y Okada, M Kato, H Minakami, Y Inoue, A Morikawa, K Otsuki, H Kimur. Reduced expression of flice-inhibitory protein (FLIP) and NFkappaB is associated with death receptor-induced cell death in human aortic endothelial cells (HAECs). Cytokine. vol 15. issue 2. 2001-12-04. PMID:11500081. |
alteration of the transcription of anti-apoptotic proteins, including inhibitor of apoptosis protein 1, 2 (ciap1, 2), tnf receptor-associated factor 1 (traf1), nuclear factor kappa b1 protein (nfkappab1), and flice-inhibitory protein (flip) was assessed by real-time reverse transcriptase-polymerase chain reaction (rt-pcr). |
2001-12-04 |
2023-08-12 |
human |
| S Chen, D C Guttridge, E Tang, S Shi, K Guan, C Y Wan. Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling. The Journal of biological chemistry. vol 276. issue 42. 2001-12-04. PMID:11500509. |
the activation of nuclear factor kappab (nf-kappa b) plays a pivotal role in the regulation of tumor necrosis factor (tnf)-mediated apoptosis. |
2001-12-04 |
2023-08-12 |
mouse |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
the effects of tumor necrosis factor (tnf) on cultured porcine granulosa cells that were obtained from preovulatory follicles were studied with regard to following parameters: 1) tnf receptor type i expression, 2) progesterone receptor and transforming growth factor beta receptor type ii (tbetar ii) as markers of luteinization, 3) proliferation, and 4) apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
supplementation of the medium with tnf leads to increased proliferation and at the same time it induces apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
our results indicate that tnf exerts an inhibitory influence on luteinization and that tnf influences the balance between follicular growth (proliferation) and atresia (apoptosis). |
2001-12-04 |
2023-08-12 |
Not clear |
| K Heyninck, R Beyaer. Crosstalk between NF-kappaB-activating and apoptosis-inducing proteins of the TNF-receptor complex. Molecular cell biology research communications : MCBRC. vol 4. issue 5. 2001-12-04. PMID:11529675. |
the cytokine tumor necrosis factor (tnf) elicits a wide range of biological responses, including inflammation, cell proliferation, differentiation, and apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |