| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Chen, D C Guttridge, E Tang, S Shi, K Guan, C Y Wan. Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling. The Journal of biological chemistry. vol 276. issue 42. 2001-12-04. PMID:11500509. |
the activation of nuclear factor kappab (nf-kappa b) plays a pivotal role in the regulation of tumor necrosis factor (tnf)-mediated apoptosis. |
2001-12-04 |
2023-08-12 |
mouse |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
the effects of tumor necrosis factor (tnf) on cultured porcine granulosa cells that were obtained from preovulatory follicles were studied with regard to following parameters: 1) tnf receptor type i expression, 2) progesterone receptor and transforming growth factor beta receptor type ii (tbetar ii) as markers of luteinization, 3) proliferation, and 4) apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
supplementation of the medium with tnf leads to increased proliferation and at the same time it induces apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| J Prange-Kiel, C Kreutzkamm, U Wehrenberg, G M Run. Role of tumor necrosis factor in preovulatory follicles of swine. Biology of reproduction. vol 65. issue 3. 2001-12-04. PMID:11514360. |
our results indicate that tnf exerts an inhibitory influence on luteinization and that tnf influences the balance between follicular growth (proliferation) and atresia (apoptosis). |
2001-12-04 |
2023-08-12 |
Not clear |
| K Heyninck, R Beyaer. Crosstalk between NF-kappaB-activating and apoptosis-inducing proteins of the TNF-receptor complex. Molecular cell biology research communications : MCBRC. vol 4. issue 5. 2001-12-04. PMID:11529675. |
the cytokine tumor necrosis factor (tnf) elicits a wide range of biological responses, including inflammation, cell proliferation, differentiation, and apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| K Heyninck, R Beyaer. Crosstalk between NF-kappaB-activating and apoptosis-inducing proteins of the TNF-receptor complex. Molecular cell biology research communications : MCBRC. vol 4. issue 5. 2001-12-04. PMID:11529675. |
this review will focus on the crosstalk that exists between proteins of the tnf receptor (tnf-r) signalosome, and which are involved in the initiation of nuclear factor kappa b (nf-kappab) activation or apoptosis. |
2001-12-04 |
2023-08-12 |
Not clear |
| P Secchiero, A Gonelli, C Celeghini, P Mirandola, L Guidotti, G Visani, S Capitani, G Zaul. Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies. Blood. vol 98. issue 7. 2001-12-04. PMID:11568010. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induced both cytotoxic (apoptosis) and cytostatic (cell cycle perturbation) effects on the human myeloid k562 cell line. |
2001-12-04 |
2023-08-12 |
human |
| J S Duffield, C F Ware, B Ryffel, J Savil. Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. The American journal of pathology. vol 159. issue 4. 2001-12-04. PMID:11583967. |
thus, soluble tnf receptor-1 significantly inhibited induction of mesangial cell apoptosis by 1) rodent m(phi) in the presence of nitric oxide synthase inhibitors or 2) human m(phi), both situations in which nitric oxide release was minimal. |
2001-12-04 |
2023-08-12 |
human |
| J S Duffield, C F Ware, B Ryffel, J Savil. Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. The American journal of pathology. vol 159. issue 4. 2001-12-04. PMID:11583967. |
furthermore, murine tnf knockout m(phi) were completely unable to induce mesangial cell apoptosis in the presence of nitric oxide synthase inhibitors. |
2001-12-04 |
2023-08-12 |
human |
| K Krasinski, I Spyridopoulos, M Kearney, D W Losord. In vivo blockade of tumor necrosis factor-alpha accelerates functional endothelial recovery after balloon angioplasty. Circulation. vol 104. issue 15. 2001-12-04. PMID:11591609. |
in vitro studies have shown that tnf inhibits cell cycle progression and induces apoptosis in endothelial cells. |
2001-12-04 |
2023-08-12 |
Not clear |
| A Colell, O Coll, C García-Ruiz, R París, C Tiribelli, N Kaplowitz, J C Fernández-Chec. Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione. Hepatology (Baltimore, Md.). vol 34. issue 5. 2001-12-04. PMID:11679967. |
mitochondrial glutathione (gsh) plays a key role against tumor necrosis factor alpha (tnf)-induced apoptosis because its depletion is known to sensitize hepatocytes to tnf. |
2001-12-04 |
2023-08-12 |
rat |
| M J Knight, C D Riffkin, A M Muscat, D M Ashley, C J Hawkin. Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells. Oncogene. vol 20. issue 41. 2001-11-01. PMID:11593384. |
fasl and tnf-related apoptosis-inducing ligand (trail) belong to a subgroup of the tnf superfamily which induce apoptosis by binding to their death domain containing receptors. |
2001-11-01 |
2023-08-12 |
human |
| K Sugiyama, Y Noda, P H. Suppressive effect of caffeine on hepatitis and apoptosis induced by tumor necrosis factor-alpha, but not by the anti-Fas antibody, in mice. Bioscience, biotechnology, and biochemistry. vol 65. issue 3. 2001-10-25. PMID:11330688. |
tumor necrosis factor (tnf)-alpha-induced hepatitis and apoptosis, as respectively assessed by serum enzyme activities and hepatic dna fragmentation were effectively suppressed by a single force-feeding of caffeine (100 mg/kg) 1.5 h before injecting the drug. |
2001-10-25 |
2023-08-12 |
mouse |
| I Peták, J A Houghto. Shared pathways: death receptors and cytotoxic drugs in cancer therapy. Pathology oncology research : POR. vol 7. issue 2. 2001-10-25. PMID:11458271. |
death ligands (tnf, fasl, trail) and their respective death receptor signaling pathways can be used to induce tumor cells to undergo apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| A H Chou, H F Tsai, L L Lin, S L Hsieh, P I Hsu, P N Hs. Enhanced proliferation and increased IFN-gamma production in T cells by signal transduced through TNF-related apoptosis-inducing ligand. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 3. 2001-10-25. PMID:11466352. |
tnf-related apoptosis-inducing ligand (trail, also called apo2l), a novel member of tnf superfamily, induces apoptosis in transformed cell lines of diverse origin. |
2001-10-25 |
2023-08-12 |
mouse |
| N Neznanov, A Kondratova, K M Chumakov, B Angres, B Zhumabayeva, V I Agol, A V Gudko. Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface. Journal of virology. vol 75. issue 21. 2001-10-25. PMID:11581409. |
poliovirus protein 3a inhibits tumor necrosis factor (tnf)-induced apoptosis by eliminating the tnf receptor from the cell surface. |
2001-10-25 |
2023-08-12 |
Not clear |
| N Neznanov, A Kondratova, K M Chumakov, B Angres, B Zhumabayeva, V I Agol, A V Gudko. Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface. Journal of virology. vol 75. issue 21. 2001-10-25. PMID:11581409. |
here, the effect of poliovirus nonstructural proteins on cell sensitivity to tumor necrosis factor (tnf)-induced (i.e., receptor-mediated) apoptosis was studied. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
insulin-like growth factors (igf-i and igf-ii) inhibit c2 skeletal myoblast differentiation and enhance tnf alpha-induced apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
addition of 20 ng/ml tnf alpha on transfer into lsm blocked differentiation, igf-ii and igfbp-5 secretion and induced apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
a lower dose of tnf alpha (1 ng/ml) while not inducing apoptosis still inhibited myoblast differentiation by 56% +/- 12, (p < 0.001), indicating that induction of apoptosis is not the sole mechanism by which tnf alpha inhibits myoblast differentiation. |
2001-10-25 |
2023-08-12 |
Not clear |