| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian Liedtke, Jörg Plümpe, Stefan Kubicka, Cynthia A Bradham, Michael P Manns, David A Brenner, Christian Trautwei. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology (Baltimore, Md.). vol 36. issue 2. 2002-08-27. PMID:12143039. |
hepatoma cells treated with tnf and cycloheximide undergo apoptosis, which is proceeded by a strong activation of jnk. |
2002-08-27 |
2023-08-12 |
Not clear |
| Michelle L Chaisson, John T Brooling, Warren Ladiges, Sophia Tsai, Nelson Faust. Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy. The Journal of clinical investigation. vol 110. issue 2. 2002-08-14. PMID:12122111. |
hepatocyte-specific inhibition of nf-kappab leads to apoptosis after tnf treatment, but not after partial hepatectomy. |
2002-08-14 |
2023-08-12 |
mouse |
| Michelle L Chaisson, John T Brooling, Warren Ladiges, Sophia Tsai, Nelson Faust. Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy. The Journal of clinical investigation. vol 110. issue 2. 2002-08-14. PMID:12122111. |
in control mice, injection of 25 microg/kg tnf caused nf-kappab nuclear translocation in virtually all hepatocytes by 30 minutes and no detectable apoptosis, while in mice expressing deltan-ikappab(alpha), nf-kappab nuclear translocation was blocked in 45% of hepatocytes, leading to apoptosis 4 hours after tnf injection. |
2002-08-14 |
2023-08-12 |
mouse |
| Robert G Batey, Jianhua Wan. Molecular pathogenesis of T lymphocyte-induced liver injury in alcoholic hepatitis. Frontiers in bioscience : a journal and virtual library. vol 7. 2002-08-13. PMID:12086911. |
cytokines, especially tnf alpha, produced from macrophages/kupffer cells, play a role in the induction of liver cell necrosis and apoptosis. |
2002-08-13 |
2023-08-12 |
rat |
| Robert G Batey, Jianhua Wan. Molecular pathogenesis of T lymphocyte-induced liver injury in alcoholic hepatitis. Frontiers in bioscience : a journal and virtual library. vol 7. 2002-08-13. PMID:12086911. |
tnf alpha can cause liver cell apoptosis through the tnf alpha receptor or fas/cd95 which is expressed by liver cells. |
2002-08-13 |
2023-08-12 |
rat |
| David H Adams, Simon C Affor. The role of cholangiocytes in the development of chronic inflammatory liver disease. Frontiers in bioscience : a journal and virtual library. vol 7. 2002-08-13. PMID:12086915. |
in chronic inflammatory biliary diseases such as primary biliary cirrhosis and primary sclerosing cholangitis, infiltrating leukocytes destroy bile ducts by killing cholangiocytes via complex molecular mechanisms involving fas-dependent apoptosis and autocrine and paracrine interactions with other members of the tnf superfamily including cd40. |
2002-08-13 |
2023-08-12 |
Not clear |
| Mohamed Rahmani, Yun Dai, Steven Gran. The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. Experimental cell research. vol 277. issue 1. 2002-08-09. PMID:12061815. |
neutralization of endogenous tnfalpha by a human soluble tnf receptor substantially blocked sb-/pma-induced cytochrome c release and apoptosis. |
2002-08-09 |
2023-08-12 |
human |
| Lisa E Hensley, Howard A Young, Peter B Jahrling, Thomas W Geisber. Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily. Immunology letters. vol 80. issue 3. 2002-08-06. PMID:11803049. |
inactivated ebov also effected increased trail expression in phm, suggesting that the tnf receptor superfamily may be involved in apoptosis of the host lymphoid cells, and that induction may occur independent of viral replication. |
2002-08-06 |
2023-08-12 |
human |
| Ziv Ben-Ari, Edith Hochhauser, Idan Burstein, Orit Papo, Ella Kaganovsky, Tatyana Krasnov, Alexey Vamichkim, Bernardo A Vidn. Role of anti-tumor necrosis factor-alpha in ischemia/reperfusion injury in isolated rat liver in a blood-free environment. Transplantation. vol 73. issue 12. 2002-07-31. PMID:12131680. |
tumor-necrosis factor (tnf)-alpha apparently mediates tissue damage by inducing apoptosis and/or necrosis in liver transplants. |
2002-07-31 |
2023-08-12 |
rat |
| S de Jong, T Timmer, F J Heijenbrok, E G de Vrie. Death receptor ligands, in particular TRAIL, to overcome drug resistance. Cancer metastasis reviews. vol 20. issue 1-2. 2002-07-30. PMID:11831647. |
the death receptor ligands tumor necrosis factor (tnf), fas ligand (fasl) and tnf-related apoptosis-inducing ligand (trail) are able to induce apoptosis by binding to their cell membrane receptors. |
2002-07-30 |
2023-08-12 |
Not clear |
| Maria Filippova, Helen Song, Jodi L Connolly, Terence S Dermody, Penelope J Duerksen-Hughe. The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis. The Journal of biological chemistry. vol 277. issue 24. 2002-07-25. PMID:11934887. |
the human papillomavirus 16 e6 protein binds to tumor necrosis factor (tnf) r1 and protects cells from tnf-induced apoptosis. |
2002-07-25 |
2023-08-12 |
human |
| Maria Filippova, Helen Song, Jodi L Connolly, Terence S Dermody, Penelope J Duerksen-Hughe. The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis. The Journal of biological chemistry. vol 277. issue 24. 2002-07-25. PMID:11934887. |
previous work in our laboratory has demonstrated that transfection of hpv 16 e6 into the tumor necrosis factor (tnf)-sensitive lm cell line protects expressing cells from tnf-induced apoptosis in a p53-independent manner, and the purpose of this study was to determine the molecular mechanism underlying this protection. |
2002-07-25 |
2023-08-12 |
human |
| K S Lang, S Fillon, D Schneider, H-G Rammensee, F Lan. Stimulation of TNF alpha expression by hyperosmotic stress. Pflugers Archiv : European journal of physiology. vol 443. issue 5-6. 2002-07-24. PMID:11889578. |
in both cell types hyperosmotic stress triggered apoptosis, which in u937 cells was significantly inhibited by neutralizing antibodies against tnf alpha and by sb203580 and was similarly elicited by exogenous addition of tnf alpha. |
2002-07-24 |
2023-08-12 |
Not clear |
| Ki-Woo Kim, Byung Ju Kim, Chul-Woong Chung, Dong-Gyu Jo, In-Ki Kim, You-Hyun Song, Yun-Kyung Kwon, Ha-Na Woo, Yong-Keun Jun. Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis. Journal of cellular biochemistry. vol 85. issue 2. 2002-07-22. PMID:11948689. |
during apoptosis of nih3t3, jurkat, rat-1, and l929 cells exposed to tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), fas, serum deprivation, or tnf-alpha, respectively, ikappabalpha was cleaved in a caspase-dependent manner. |
2002-07-22 |
2023-08-12 |
Not clear |
| Ravid Sasson, Neomi Winder, Salem Kees, Abraham Amsterda. Induction of apoptosis in granulosa cells by TNF alpha and its attenuation by glucocorticoids involve modulation of Bcl-2. Biochemical and biophysical research communications. vol 294. issue 1. 2002-07-22. PMID:12054739. |
induction of apoptosis in granulosa cells by tnf alpha and its attenuation by glucocorticoids involve modulation of bcl-2. |
2002-07-22 |
2023-08-12 |
human |
| Ravid Sasson, Neomi Winder, Salem Kees, Abraham Amsterda. Induction of apoptosis in granulosa cells by TNF alpha and its attenuation by glucocorticoids involve modulation of Bcl-2. Biochemical and biophysical research communications. vol 294. issue 1. 2002-07-22. PMID:12054739. |
induction of apoptosis and suppression of steroidogenesis by tnf alpha in primary preovulatory rat and human granulosa cells, as well as, in human granulosa cells immortalized by mutated p53, were characterized in the present work. |
2002-07-22 |
2023-08-12 |
human |
| Ravid Sasson, Neomi Winder, Salem Kees, Abraham Amsterda. Induction of apoptosis in granulosa cells by TNF alpha and its attenuation by glucocorticoids involve modulation of Bcl-2. Biochemical and biophysical research communications. vol 294. issue 1. 2002-07-22. PMID:12054739. |
dexamethasone (dex) and hydrocortisone efficiently suppressed tnf alpha-induced apoptosis in granulosa cells. |
2002-07-22 |
2023-08-12 |
human |
| Ravid Sasson, Neomi Winder, Salem Kees, Abraham Amsterda. Induction of apoptosis in granulosa cells by TNF alpha and its attenuation by glucocorticoids involve modulation of Bcl-2. Biochemical and biophysical research communications. vol 294. issue 1. 2002-07-22. PMID:12054739. |
this reduction can be explained only in part by elimination of cells through apoptosis, since loss of steroidogenic capacity was much higher and faster than the rate and extent of loss of cell viability induced by tnf alpha, suggesting independent mechanisms for tnf alpha-induction of apoptosis and tnf alpha-suppression of steroidogenesis. |
2002-07-22 |
2023-08-12 |
human |
| A Ortiz, C Lorz, P Justo, M P Catalán, J Egid. Contribution of apoptotic cell death to renal injury. Journal of cellular and molecular medicine. vol 5. issue 1. 2002-07-22. PMID:12067448. |
death ligands and receptors, such as tnf and fasl, proapoptotic and antiapoptotic bcl-2 family members and caspases have all been shown to participate in apoptosis regulation in the course of renal injury. |
2002-07-22 |
2023-08-12 |
Not clear |
| Youngsoo Kim, Nanjoo Suh, Michael Sporn, John C Ree. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. The Journal of biological chemistry. vol 277. issue 25. 2002-07-19. PMID:11940602. |
trail (apo2 ligand) is a member of the tumor necrosis factor (tnf) family of cytokines that induces apoptosis. |
2002-07-19 |
2023-08-12 |
Not clear |