| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huizhen Wang, Yiqiang Zhang, Liwen Cao, Hong Han, Jingxiong Wang, Baofeng Yang, Stanley Nattel, Zhiguo Wan. HERG K+ channel, a regulator of tumor cell apoptosis and proliferation. Cancer research. vol 62. issue 17. 2002-10-03. PMID:12208728. |
here, we show that herg conductance markedly promotes h2o2-induced apoptosis of various tumor cells, whereas herg expression facilitates the tumor cell proliferation caused by tumor necrosis factor (tnf) ligand (tnf-alpha). |
2002-10-03 |
2023-08-12 |
human |
| Sarah Baatout, Hanane Derradji, Olivier Petitfour, Hanna von Suchodoletz, Max Mergea. [Mechanisms of radio-induced apoptosis]. Canadian journal of physiology and pharmacology. vol 80. issue 7. 2002-09-27. PMID:12184318. |
first, are summarized the main induction pathways of radiation-induced apoptosis by which extracellular (tumor necrosis factor (tnf), fas ligand, tnf-related apoptosis-inducing ligand (trail)) and intracellular (mitochondria and caspases) signals are integrated. |
2002-09-27 |
2023-08-12 |
Not clear |
| Christopher Hull, Graeme McLean, Fred Wong, Patrick J Duriez, Aly Karsa. Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase. Journal of immunology (Baltimore, Md. : 1950). vol 169. issue 5. 2002-09-27. PMID:12193732. |
lipopolysaccharide signals an endothelial apoptosis pathway through tnf receptor-associated factor 6-mediated activation of c-jun nh2-terminal kinase. |
2002-09-27 |
2023-08-12 |
Not clear |
| Christopher Hull, Graeme McLean, Fred Wong, Patrick J Duriez, Aly Karsa. Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase. Journal of immunology (Baltimore, Md. : 1950). vol 169. issue 5. 2002-09-27. PMID:12193732. |
inflammatory mediators such as tnf and bacterial lps do not cause significant apoptosis of endothelial cells unless the expression of cytoprotective genes is blocked. |
2002-09-27 |
2023-08-12 |
Not clear |
| C Choi, C Cha. Expression of tumour necrosis factor-alpha is associated with apoptosis in lungs of pigs experimentally infected with porcine reproductive and respiratory syndrome virus. Research in veterinary science. vol 72. issue 1. 2002-09-23. PMID:12002637. |
expression of tumour necrosis factor (tnf)-alpha and its association with apoptosis was examined in lungs from pig experimentally inoculated with porcine reproductive and respiratory syndrome virus (prrsv). |
2002-09-23 |
2023-08-12 |
Not clear |
| Asok Mukhopadhyay, Shishir Shishodia, Jill Suttles, Katherine Brittingham, Betty Lamothe, Ramdevi Nimmanapalli, Kapil N Bhalla, Bharat B Aggarwa. Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors. The Journal of biological chemistry. vol 277. issue 34. 2002-09-23. PMID:12060665. |
because bcr-abl is known to provide mitogenic signals through suppression of apoptosis, we investigated the effect of this oncogene product on signaling by tumor necrosis factor (tnf), a proapoptotic cytokine. |
2002-09-23 |
2023-08-12 |
human |
| Zeng-qiang Yuan, Richard I Feldman, Mei Sun, Nancy E Olashaw, Domenico Coppola, Gene E Sussman, Sue A Shelley, Santo V Nicosia, Jin Q Chen. Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells. The Journal of biological chemistry. vol 277. issue 33. 2002-09-20. PMID:12048203. |
furthermore, phosphatidylinositol 3-kinase inhibitor or dominant negative akt2 significantly enhances uv- and tnf alpha-induced apoptosis, whereas expression of constitutively active akt2 inhibits programmed cell death in response to uv and tnfalpha -induced apoptosis by inhibition of stress kinases and provide the first evidence that akt inhibits stress kinase jnk through activation of the nf kappa b pathway. |
2002-09-20 |
2023-08-12 |
human |
| Byung Ju Kim, Mi-Suk Kim, Ki-Bae Kim, Ki-Woo Kim, Yeon-Mi Hong, In-Ki Kim, Han-Woong Lee, Yong-Keun Jun. Sensitizing effects of cadmium on TNF-alpha- and TRAIL-mediated apoptosis of NIH3T3 cells with distinct expression patterns of p53. Carcinogenesis. vol 23. issue 9. 2002-09-18. PMID:12189181. |
tumor necrosis factor (tnf)-alpha and tnf-related apoptosis inducing ligand (trail) share a common signaling pathway. |
2002-09-18 |
2023-08-12 |
mouse |
| Marcus Spies, Vicky L Chappell, Mohan R Dasu, David N Herndon, James C Thompson, Steven E Wol. Role of TNF-alpha in gut mucosal changes after severe burn. American journal of physiology. Gastrointestinal and liver physiology. vol 283. issue 3. 2002-09-17. PMID:12181186. |
we hypothesized that tumor necrosis factor (tnf)-alpha-tnf receptor (tnfr) interaction activates apoptosis in small bowel mucosal cells after severe burn. |
2002-09-17 |
2023-08-12 |
mouse |
| Seiichiro Sakao, Koichiro Tatsumi, Hidetoshi Igari, Reiko Watanabe, Yuji Shino, Hiroshi Shirasawa, Takayuki Kuriyam. Association of tumor necrosis factor-alpha gene promoter polymorphism with low attenuation areas on high-resolution CT in patients with COPD. Chest. vol 122. issue 2. 2002-09-13. PMID:12171811. |
because tumor necrosis factor (tnf)-alpha is assumed to play an important role in the induction of apoptosis, and allele 2 of the polymorphism at position--308 in the promoter of the tnf-alpha gene has been associated with alteration of tnf-alpha secretion in vitro, we hypothesized that genotypes containing this allele would show more destructive emphysematous changes of the lung. |
2002-09-13 |
2023-08-12 |
Not clear |
| George G Chen, Paul B S Lai, Xu Hu, Isa K Y Lam, Ernest C W Chak, Ying S Chun, Wan Y La. Negative correlation between the ratio of Bax to Bcl-2 and the size of tumor treated by culture supernatants from Kupffer cells. Clinical & experimental metastasis. vol 19. issue 5. 2002-09-13. PMID:12198774. |
the expression of tnf alpha and the occurrence of apoptosis were also increased in tumor treated with culture supernatants from activated kupffer cells, compared with those which received no treatment. |
2002-09-13 |
2023-08-12 |
mouse |
| G S D Reid, S Bharya, H-G Klingemann, K R Schult. Differential killing of pre-B acute lymphoblastic leukaemia cells by activated NK cells and the NK-92 ci cell line. Clinical and experimental immunology. vol 129. issue 2. 2002-09-11. PMID:12165082. |
deficiencies in tnf family mediated apoptosis, phosphoinositide-3 kinase dependent and phosphoinositide-3 kinase independent killing limit the efficiency of nk-92 ci against pre-b acute lymphoblastic leukaemia cells. |
2002-09-11 |
2023-08-12 |
Not clear |
| Kai-Li He, Adrian T Tin. A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Molecular and cellular biology. vol 22. issue 17. 2002-09-09. PMID:12167698. |
a20 inhibits tumor necrosis factor (tnf) alpha-induced apoptosis by disrupting recruitment of tradd and rip to the tnf receptor 1 complex in jurkat t cells. |
2002-09-09 |
2023-08-12 |
Not clear |
| Jennifer L Marcinkiewicz, Sharon K Balchak, Leisa J Morriso. The involvement of tumor necrosis factor-alpha (TNF) as an intraovarian regulator of oocyte apoptosis in the neonatal rat . Frontiers in bioscience : a journal and virtual library. vol 7. 2002-08-30. PMID:12161343. |
the involvement of tumor necrosis factor-alpha (tnf) as an intraovarian regulator of oocyte apoptosis in the neonatal rat . |
2002-08-30 |
2023-08-12 |
rat |
| Jennifer L Marcinkiewicz, Sharon K Balchak, Leisa J Morriso. The involvement of tumor necrosis factor-alpha (TNF) as an intraovarian regulator of oocyte apoptosis in the neonatal rat . Frontiers in bioscience : a journal and virtual library. vol 7. 2002-08-30. PMID:12161343. |
our results show that tnf can decrease oocyte and primordial follicle number through stimulation of oocyte apoptosis in vitro. |
2002-08-30 |
2023-08-12 |
rat |
| Sang-Youel Park, Dai-Wu Seo. Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis. Biochemical and biophysical research communications. vol 295. issue 2. 2002-08-29. PMID:12150980. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a type ii transmembrane cytokine and a potent inducer of apoptosis. |
2002-08-29 |
2023-08-12 |
Not clear |
| Myoung Woo Lee, Soon Cheol Park, Joung-Hun Kim, In-Ki Kim, Kun Soo Han, Kyung Yong Kim, Won Bok Lee, Yong-Keun Jung, Sung Su Ki. The involvement of oxidative stress in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in HeLa cells. Cancer letters. vol 182. issue 1. 2002-08-29. PMID:12175526. |
the involvement of oxidative stress in tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis in hela cells. |
2002-08-29 |
2023-08-12 |
human |
| R G Oshim. Apoptosis and keratin intermediate filaments. Cell death and differentiation. vol 9. issue 5. 2002-08-28. PMID:11973607. |
however, recent studies have also revealed an unexpected protective role for keratin 8 during tnf and fas mediated apoptosis. |
2002-08-28 |
2023-08-12 |
Not clear |
| Vassiliki Poulaki, Constantine S Mitsiades, Vassiliki Kotoula, Sophia Tseleni-Balafouta, Avi Ashkenazi, Demetrios A Koutras, Nicholas Mitsiade. Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells. The American journal of pathology. vol 161. issue 2. 2002-08-28. PMID:12163389. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)/apo2 ligand selectively kills neoplastic cells, including thyroid carcinoma cells (mitsiades et al: thyroid carcinoma cells are resistant to fas-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. |
2002-08-28 |
2023-08-12 |
Not clear |
| Christian Liedtke, Jörg Plümpe, Stefan Kubicka, Cynthia A Bradham, Michael P Manns, David A Brenner, Christian Trautwei. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology (Baltimore, Md.). vol 36. issue 2. 2002-08-27. PMID:12143039. |
tumor necrosis factor (tnf) triggers distinct pathways in liver cells through tnf receptor 1 (tnf-r1) via adapter molecules, including the intracellular cascades leading to apoptosis, nuclear factor-kappa b (nf-kappa b), and jun kinase (jnk) activation. |
2002-08-27 |
2023-08-12 |
Not clear |