| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Volejnikova, S C Marks, D T Grave. Tumor necrosis factor modulates apoptosis of monocytes in areas of developmentally regulated bone remodeling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 17. issue 6. 2002-11-19. PMID:12054175. |
in contrast, the number of monocytes, the rate of monocyte apoptosis, and the formation of osteoclasts in the occlusal area associated with bone resorption occurred independently of tnf activity. |
2002-11-19 |
2023-08-12 |
mouse |
| Zongbing You, Lee V Madrid, Daniel Saims, John Sedivy, Cun-Yu Wan. c-Myc sensitizes cells to tumor necrosis factor-mediated apoptosis by inhibiting nuclear factor kappa B transactivation. The Journal of biological chemistry. vol 277. issue 39. 2002-11-13. PMID:12149248. |
nuclear factor kappab (nf-kappab) plays a key role in suppression of tumor necrosis factor (tnf)-mediated apoptosis by inducing a variety of anti-apoptotic genes. |
2002-11-13 |
2023-08-12 |
Not clear |
| A Pituch-Noworolsk. [Biological properties and sensitivity to induction therapy of differentiated cells expressing atypical immunophenotype in acute leukemia of children]. Folia medica Cracoviensia. vol 42. issue 3. 2002-11-06. PMID:12353422. |
the purpose of the study was: precise description of atypical immunophenotypes and analysis of their frequency in different types of acute leukaemia, analysis of association between expression of atypical immunophenotypes and the level of initial leukocytosis, percentage of blast cells in peripheral blood, expression of cd34, analysis of frequency of multidrug resistance molecule (mdr) expression and association between mdr and immunophenotypes of leukaemia cells, analysis of association between atypical immunophenotypes and proliferation, secretion of cytokines (il-6, tnf) and spontaneous apoptosis of leukaemia cells, analysis of association between atypical immunophenotypes and sensitivity to induction therapy. |
2002-11-06 |
2023-08-12 |
mouse |
| Gary Chan, Denise G Hemmings, Andrew D Yurochko, Larry J Guilber. Human cytomegalovirus-caused damage to placental trophoblasts mediated by immediate-early gene-induced tumor necrosis factor-alpha. The American journal of pathology. vol 161. issue 4. 2002-11-05. PMID:12368210. |
antibody to tumor necrosis factor (tnf)-alpha completely inhibited infection-induced trophoblast apoptosis and cell loss, as did co-incubation with epidermal growth factor, known to inhibit trophoblast apoptosis. |
2002-11-05 |
2023-08-12 |
human |
| Oskar W Rokhlin, Rebecca A Glover, Agshin F Taghiyev, Natalya V Guseva, Richard E B Seftor, Inna Shyshynova, Andrei V Gudkov, Michael B Cohe. Bisindolylmaleimide IX facilitates tumor necrosis factor receptor family-mediated cell death and acts as an inhibitor of transcription. The Journal of biological chemistry. vol 277. issue 36. 2002-10-29. PMID:12091392. |
several studies have shown that bis potentiate tumor necrosis factor (tnf) receptor family-mediated apoptosis in lymphoid and dendritic cells, but the inhibition of protein kinase c cannot account for these effects (zhou, t., song, l., yang, p., wang, z., lui, d., and jope, r. s. (1999) nat. |
2002-10-29 |
2023-08-12 |
human |
| Monika Weingärtner, Daniela Siegmund, Ulrich Schlecht, Mariola Fotin-Mleczek, Peter Scheurich, Harald Wajan. Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis. The Journal of biological chemistry. vol 277. issue 38. 2002-10-24. PMID:12105203. |
endogenous membrane tumor necrosis factor (tnf) is a potent amplifier of tnf receptor 1-mediated apoptosis. |
2002-10-24 |
2023-08-12 |
Not clear |
| Monika Weingärtner, Daniela Siegmund, Ulrich Schlecht, Mariola Fotin-Mleczek, Peter Scheurich, Harald Wajan. Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis. The Journal of biological chemistry. vol 277. issue 38. 2002-10-24. PMID:12105203. |
triggering of tnf-r1 by agonistic antibodies led to cell-type specific induction of endogenous tnf and apoptosis, the latter of which was abrogated by neutralizing tnf specific antibodies. |
2002-10-24 |
2023-08-12 |
Not clear |
| Monika Weingärtner, Daniela Siegmund, Ulrich Schlecht, Mariola Fotin-Mleczek, Peter Scheurich, Harald Wajan. Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis. The Journal of biological chemistry. vol 277. issue 38. 2002-10-24. PMID:12105203. |
geldanamycin failed to inhibit apoptosis induction by a combination of agonistic tnf-r1- and tnf-r2-specific antibodies, indicating that both tnf receptors co-operate in tnf-r1-triggered apoptosis in kym-1 cells. |
2002-10-24 |
2023-08-12 |
Not clear |
| Monika Weingärtner, Daniela Siegmund, Ulrich Schlecht, Mariola Fotin-Mleczek, Peter Scheurich, Harald Wajan. Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis. The Journal of biological chemistry. vol 277. issue 38. 2002-10-24. PMID:12105203. |
moreover, we give evidence that this mechanism circumvents the need of the prolonged presence of exogenous soluble tnf for tnf-r1-mediated apoptosis induction. |
2002-10-24 |
2023-08-12 |
Not clear |
| Wilfried Kugler, Bernhard Erdlenbruch, Anja Jünemann, Dagmar Heinemann, Hansjörg Eibl, Max Lakome. Erucylphosphocholine-induced apoptosis in glioma cells: involvement of death receptor signalling and caspase activation. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358763. |
inhibition of the tnf or trail signalling pathway with antagonistic antibodies or fusion proteins did not affect apoptosis induced by erpc, and a dominant-negative fadd construct did not abolish erpc-induced effects. |
2002-10-18 |
2023-08-12 |
Not clear |
| Karoly Toth, Mohan Kuppuswamy, Konstantin Doronin, Oksana Doronina, Drew Lichtenstein, Ann Tollefson, William Wol. Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region. Virology. vol 301. issue 1. 2002-10-18. PMID:12359450. |
earlier work further showed that another adenovirus e3-coded protein, e3-14.7k, inhibits apoptosis induced by tnf. |
2002-10-18 |
2023-08-12 |
Not clear |
| Karoly Toth, Mohan Kuppuswamy, Konstantin Doronin, Oksana Doronina, Drew Lichtenstein, Ann Tollefson, William Wol. Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region. Virology. vol 301. issue 1. 2002-10-18. PMID:12359450. |
most of the above studies have been conducted using viable virus mutants that lack one or more of the genes for rid, e3-14.7k, or e1b-19k (this protein, coded by the e1b transcription unit, also inhibits apoptosis via the tnf and fas pathways). |
2002-10-18 |
2023-08-12 |
Not clear |
| Byung-Chul Kim, Heung-Tae Kim, Mizuko Mamura, Indu S Ambudkar, Kyeong-Sook Choi, Seong-Jin Ki. Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12077131. |
tumor necrosis factor (tnf) plays an import role in the control of apoptosis. |
2002-10-17 |
2023-08-12 |
rat |
| Byung-Chul Kim, Heung-Tae Kim, Mizuko Mamura, Indu S Ambudkar, Kyeong-Sook Choi, Seong-Jin Ki. Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12077131. |
these results suggest that tnf induces apoptosis by a mechanism that involves increasing ca(2+) release from the er and suppression of bcl-2 expression. |
2002-10-17 |
2023-08-12 |
rat |
| Wen-Shu Wu, Zhi-Xiang Xu, Kun-Sang Chan. The promyelocytic leukemia protein represses A20-mediated transcription. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12080044. |
in a previous study, we found that pml sensitizes tumor necrosis factor-induced apoptosis in tumor necrosis factor (tnf)-resistant u2os cells. |
2002-10-17 |
2023-08-12 |
Not clear |
| Wen-Shu Wu, Zhi-Xiang Xu, Kun-Sang Chan. The promyelocytic leukemia protein represses A20-mediated transcription. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12080044. |
the zinc finger protein a20 is a target gene of nf kappa b inducible by tnf alpha, and it is a potent inhibitor of tnf-induced apoptosis. |
2002-10-17 |
2023-08-12 |
Not clear |
| Anna Colell, Albert Morales, José C Fernández-Checa, Carmen García-Rui. Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-alpha-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation. Possible role of ganglioside GD3. FEBS letters. vol 526. issue 1-3. 2002-10-17. PMID:12208520. |
in the present study we assessed the contribution of acidic sphingomyelinase (asmase), a ceramide generating enzyme, in tumor necrosis factor (tnf)-mediated apoptosis in human colon ht-29 cells. |
2002-10-17 |
2023-08-12 |
human |
| Anna Colell, Albert Morales, José C Fernández-Checa, Carmen García-Rui. Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-alpha-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation. Possible role of ganglioside GD3. FEBS letters. vol 526. issue 1-3. 2002-10-17. PMID:12208520. |
tnf induced apoptosis in ht-29 cells in a time- and dose-dependent fashion. |
2002-10-17 |
2023-08-12 |
human |
| Hidekazu Inoue, Katsuya Shiraki, Shigeru Ohmori, Takahisa Sakai, Masatoshi Deguchi, Takenari Yamanaka, Hiroshi Okano, Takeshi Nakan. Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis. International journal of molecular medicine. vol 9. issue 5. 2002-10-16. PMID:11956660. |
hdai augmented tnf family-related apoptosis in ls 180 cells and ht-29 cells. |
2002-10-16 |
2023-08-12 |
human |
| Rakesh Sharma, Stefan D Anke. Cytokines, apoptosis and cachexia: the potential for TNF antagonism. International journal of cardiology. vol 85. issue 1. 2002-10-10. PMID:12163221. |
cytokines, apoptosis and cachexia: the potential for tnf antagonism. |
2002-10-10 |
2023-08-12 |
Not clear |