| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haili Lü, Qiuhang Zhang, Bo Ya. [Stat3 antisense oligodeoxynucleotide induces apoptosis in laryngeal carcinoma cells by regulating apoptosis-related factors]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 24. issue 4. 2011-08-25. PMID:20422978. |
[stat3 antisense oligodeoxynucleotide induces apoptosis in laryngeal carcinoma cells by regulating apoptosis-related factors]. |
2011-08-25 |
2023-08-12 |
Not clear |
| Haili Lü, Qiuhang Zhang, Bo Ya. [Stat3 antisense oligodeoxynucleotide induces apoptosis in laryngeal carcinoma cells by regulating apoptosis-related factors]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 24. issue 4. 2011-08-25. PMID:20422978. |
to study the mechanism of apoptosis in laryngeal carcinoma cell induced by stat3 antisense oligodeoxynucleotide (asodn). |
2011-08-25 |
2023-08-12 |
Not clear |
| Jang Choon Lee, Kwang Seok Ahn, Soo-Jin Jeong, Ji Hoon Jung, Tae-Rin Kwon, Yun-Hee Rhee, Sun-Hee Kim, Si-Young Kim, Hwi-Joong Yoon, Shudong Zhu, Chang-Yan Chen, Sung-Hoon Ki. Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells. Journal of cellular biochemistry. vol 112. issue 6. 2011-08-25. PMID:21344490. |
using several myelogenous cell lines, the effect of genipin (an active compound of gardenia fruit) on the stat3 pathway and apoptosis was investigated. |
2011-08-25 |
2023-08-12 |
Not clear |
| Jang Choon Lee, Kwang Seok Ahn, Soo-Jin Jeong, Ji Hoon Jung, Tae-Rin Kwon, Yun-Hee Rhee, Sun-Hee Kim, Si-Young Kim, Hwi-Joong Yoon, Shudong Zhu, Chang-Yan Chen, Sung-Hoon Ki. Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells. Journal of cellular biochemistry. vol 112. issue 6. 2011-08-25. PMID:21344490. |
our data suggest that through regulation of src and shp-1, genipin antagonizes stat3 for the induction of apoptosis in myeloma cells. |
2011-08-25 |
2023-08-12 |
Not clear |
| Michele S Redell, Marcos J Ruiz, Todd A Alonzo, Robert B Gerbing, David J Tweard. Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. Blood. vol 117. issue 21. 2011-08-23. PMID:21447830. |
stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule stat3 inhibitor. |
2011-08-23 |
2023-08-12 |
Not clear |
| Michele S Redell, Marcos J Ruiz, Todd A Alonzo, Robert B Gerbing, David J Tweard. Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. Blood. vol 117. issue 21. 2011-08-23. PMID:21447830. |
the objectives of this study were: (1) to characterize stat3 signaling patterns in aml cells lines and primary pediatric samples; and (2) to test the efficacy and potency of a novel stat3 inhibitor in inducing apoptosis in aml cells. |
2011-08-23 |
2023-08-12 |
Not clear |
| Michele S Redell, Marcos J Ruiz, Todd A Alonzo, Robert B Gerbing, David J Tweard. Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. Blood. vol 117. issue 21. 2011-08-23. PMID:21447830. |
our novel small-molecule stat3 inhibitor, c188-9, inhibited g-csf-induced stat3 phosphorylation, induced apoptosis in aml cell lines and primary samples, and inhibited aml blast colony formation with potencies in the low micromolar range. |
2011-08-23 |
2023-08-12 |
Not clear |
| Yu-Cai Wang, Lian-He Zheng, Bao-An Ma, Yong Zhou, Ming-Hua Zhang, Dian-Zhong Zhang, Qing-Yu Fa. Clinical value of signal transducers and activators of transcription 3 (STAT3) gene expression in human osteosarcoma. Acta histochemica. vol 113. issue 4. 2011-08-22. PMID:20546860. |
mtt and flow cytometric assays were performed to analyze the effect of stat3 inhibition on proliferation and apoptosis of osteosarcoma cells. |
2011-08-22 |
2023-08-12 |
human |
| Yu-Cai Wang, Lian-He Zheng, Bao-An Ma, Yong Zhou, Ming-Hua Zhang, Dian-Zhong Zhang, Qing-Yu Fa. Clinical value of signal transducers and activators of transcription 3 (STAT3) gene expression in human osteosarcoma. Acta histochemica. vol 113. issue 4. 2011-08-22. PMID:20546860. |
rnai-mediated stat3 inhibition could induce proliferation inhibition and apoptosis enhancement in osteosarcoma cells, which might be associated with inhibition of some anti-apoptosis genes. |
2011-08-22 |
2023-08-12 |
human |
| Yan Liu, Aiguo Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Li. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis : an international journal on programmed cell death. vol 16. issue 5. 2011-08-16. PMID:21311975. |
xzh-5 inhibits stat3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. |
2011-08-16 |
2023-08-12 |
human |
| Yan Liu, Aiguo Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Li. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis : an international journal on programmed cell death. vol 16. issue 5. 2011-08-16. PMID:21311975. |
in this study, we demonstrated that blocking stat3 phosphorylation with stat3 small molecule inhibitors sd-1029 and stattic caused apoptosis in hcc cells. |
2011-08-16 |
2023-08-12 |
human |
| Yan Liu, Aiguo Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Li. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis : an international journal on programmed cell death. vol 16. issue 5. 2011-08-16. PMID:21311975. |
the inhibition of stat3 in hcc cells resulted in the induction of apoptosis and reduction of colony forming ability. |
2011-08-16 |
2023-08-12 |
human |
| Sarah Ball, Chenglong Li, Pui-Kai Li, Jiayuh Li. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells. PloS one. vol 6. issue 4. 2011-08-16. PMID:21526200. |
the small molecule, lll12, inhibits stat3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells. |
2011-08-16 |
2023-08-12 |
Not clear |
| Sarah Ball, Chenglong Li, Pui-Kai Li, Jiayuh Li. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells. PloS one. vol 6. issue 4. 2011-08-16. PMID:21526200. |
lll12 was able to inhibit stat3 phosphorylation, decrease cell viability and induce apoptosis in medulloblastoma and glioblastoma cell lines with elevated levels of p-stat3 (y705). |
2011-08-16 |
2023-08-12 |
Not clear |
| Ahmed Malki, Amal Yousse. Antidiabetic drug metformin induces apoptosis in human MCF breast cancer via targeting ERK signaling. Oncology research. vol 19. issue 6. 2011-08-16. PMID:21776823. |
metformin induced apoptosis by arresting cells in g1 phase and reducing cyclin d level and increasing the expression of p21 and cyclin e. molecular and cellular studies indicated that metformin significantly elevated p53 and bax levels and reduced stat3 and bcl-2. |
2011-08-16 |
2023-08-12 |
human |
| Chen Huang, Tao Jiang, Lin Zhu, Jun Liu, Jun Cao, Ke-Jian Huang, Zheng-Jun Qi. STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo. International journal of oncology. vol 38. issue 6. 2011-08-09. PMID:21479358. |
stat3 regulates a number of pathways important in tumorigenesis including cell cycle progression, apoptosis, tumor angiogenesis, invasion and metastasis, and tumor cell evasion of the immune system. |
2011-08-09 |
2023-08-12 |
human |
| Anna Scuto, Maciej Kujawski, Claudia Kowolik, Ludmila Krymskaya, Lin Wang, Lawrence M Weiss, David Digiusto, Hua Yu, Stephen Forman, Richard Jov. STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma. Cancer research. vol 71. issue 9. 2011-08-09. PMID:21521803. |
direct inhibition of stat3 with short hairpin rna suppressed the growth of human abc-like dlbcl in mouse models in a manner associated with apoptosis, repression of stat3 target genes, and inhibition of a tumor-promoting microenvironment. |
2011-08-09 |
2023-08-12 |
mouse |
| X H Wang, B R Liu, B Qu, H Xing, S L Gao, J M Yin, X F Wang, Y Q Chen. Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. Neoplasma. vol 58. issue 2. 2011-08-04. PMID:21275467. |
silencing stat3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. |
2011-08-04 |
2023-08-12 |
Not clear |
| X H Wang, B R Liu, B Qu, H Xing, S L Gao, J M Yin, X F Wang, Y Q Chen. Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. Neoplasma. vol 58. issue 2. 2011-08-04. PMID:21275467. |
the genesis and development of hepatocellular carcinoma (hcc) is related to the abnormity of signaling pathway, telomerase, cell cycle, apoptosis, angiogenesis, and others, in which stat3 signaling pathway plays a key role. |
2011-08-04 |
2023-08-12 |
Not clear |
| X H Wang, B R Liu, B Qu, H Xing, S L Gao, J M Yin, X F Wang, Y Q Chen. Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. Neoplasma. vol 58. issue 2. 2011-08-04. PMID:21275467. |
the results demonstrated that stat3 signaling pathway may participate in hcc genesis and development through regulating the protein expression of other signaling pathway, telomerase, apoptosis, cell cycle and angiogenesis; thereby, blockade of the stat3 pathway represents a potential strategy for future treatment. |
2011-08-04 |
2023-08-12 |
Not clear |