| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marisa Granato, Celeste Rizzello, Maria Saveria Gilardini Montani, Laura Cuomo, Marina Vitillo, Roberta Santarelli, Roberta Gonnella, Gabriella D'Orazi, Alberto Faggioni, Mara Ciron. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. The Journal of nutritional biochemistry. vol 41. 2017-12-22. PMID:28092744. |
quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting pi3k/akt/mtor and stat3 signaling pathways. |
2017-12-22 |
2023-08-13 |
Not clear |
| Feng-Ting Liu, Li Jia, Ping Wang, Huaqing Wang, Timothy W Farren, Samir G Agrawa. STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. Oncotarget. vol 7. issue 22. 2017-12-20. PMID:27074565. |
stat3 and nf-κb cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. |
2017-12-20 |
2023-08-13 |
Not clear |
| Feng-Ting Liu, Li Jia, Ping Wang, Huaqing Wang, Timothy W Farren, Samir G Agrawa. STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. Oncotarget. vol 7. issue 22. 2017-12-20. PMID:27074565. |
we hypothesize that the sensitivity of cll cells to spontaneous apoptosis may be associated with the constitutive activities of transcription factors stat3 and/or nf-κb. |
2017-12-20 |
2023-08-13 |
Not clear |
| Feng-Ting Liu, Li Jia, Ping Wang, Huaqing Wang, Timothy W Farren, Samir G Agrawa. STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. Oncotarget. vol 7. issue 22. 2017-12-20. PMID:27074565. |
we now show that the sensitivity of fresh cll cells to spontaneous apoptosis is highly variable among different patients during 48 hours' cell culture and inversely correlated with in vivo constitutively activated stat3 and nf-κb (p < 0.001). |
2017-12-20 |
2023-08-13 |
Not clear |
| Feng-Ting Liu, Li Jia, Ping Wang, Huaqing Wang, Timothy W Farren, Samir G Agrawa. STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. Oncotarget. vol 7. issue 22. 2017-12-20. PMID:27074565. |
our data suggest that the sensitivity of cll cells to in vitro spontaneous apoptosis is co-regulated by constitutively activated stat3 and nf-κb and reflects the in vivo chemo-responsiveness and clinical outcomes. |
2017-12-20 |
2023-08-13 |
Not clear |
| Chongqiang Zhao, Wenlong Wang, Wenying Yu, David Jou, Yina Wang, Haiyan Ma, Hui Xiao, Hua Qin, Cuntai Zhang, Jiagao Lü, Sheng Li, Chenglong Li, Jiayuh Lin, Li Li. A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells. Oncotarget. vol 7. issue 11. 2017-11-21. PMID:26883202. |
we demonstrated that ly5 inhibited constitutive interleukin-6 (il-6)-induced stat3 phosphorylation, stat3 nuclear translocation, decreased stat3 downstream targeted gene expression and induced apoptosis in liver and colon cancer cells. |
2017-11-21 |
2023-08-13 |
mouse |
| Qingsheng Ye, Cuida Meng, Yannan Shen, Jianjun Ji, Xiaochun Wang, Sheng Zhou, Lili Jia, Yanqun Wan. Caveolin-1 Mediates Low-Intensity Ultrasound-Induced Apoptosis via Downregulation of Signal Transducer and Activator of Transcription 3 Phosphorylation in Laryngeal Carcinoma Cells. Ultrasound in medicine & biology. vol 42. issue 9. 2017-11-20. PMID:27289429. |
in addition, inhibition of cav-1 expression promoted phosphorylation of signal transducer and activator of transcription 3 (stat3), suggesting that the stat3 signaling pathway was involved in low-intensity ultrasound-induced apoptosis via cav-1 regulation. |
2017-11-20 |
2023-08-13 |
Not clear |
| Yan Hu, Chengguang Zhao, Hailun Zheng, Kongqin Lu, Dengjian Shi, Zhiguo Liu, Xuanxuan Dai, Yi Zhang, Xiuhua Zhang, Wanle Hu, Guang Lian. A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anti-cancer drugs. vol 28. issue 4. 2017-11-16. PMID:28067673. |
a novel stat3 inhibitor ho-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. |
2017-11-16 |
2023-08-13 |
human |
| Yan Hu, Chengguang Zhao, Hailun Zheng, Kongqin Lu, Dengjian Shi, Zhiguo Liu, Xuanxuan Dai, Yi Zhang, Xiuhua Zhang, Wanle Hu, Guang Lian. A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anti-cancer drugs. vol 28. issue 4. 2017-11-16. PMID:28067673. |
in addition, independent of the ros pathway, direct stat3 inhibition was observed in ho-3867-induced cell apoptosis. |
2017-11-16 |
2023-08-13 |
human |
| Yan Hu, Chengguang Zhao, Hailun Zheng, Kongqin Lu, Dengjian Shi, Zhiguo Liu, Xuanxuan Dai, Yi Zhang, Xiuhua Zhang, Wanle Hu, Guang Lian. A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anti-cancer drugs. vol 28. issue 4. 2017-11-16. PMID:28067673. |
taken together, the results of this work suggest that both the ros-dependent er stress and stat3 pathways were implicated in the cell apoptosis induced by the novel compound ho-3867. |
2017-11-16 |
2023-08-13 |
human |
| Mei Tan, Ying Rong, Qiong Su, Yan Che. Artesunate induces apoptosis via inhibition of STAT3 in THP-1 cells. Leukemia research. vol 62. 2017-11-16. PMID:29031126. |
artesunate induces apoptosis via inhibition of stat3 in thp-1 cells. |
2017-11-16 |
2023-08-13 |
Not clear |
| Renata Feuerborn, Susen Becker, Francesco Potì, Petra Nagel, Martin Brodde, Harmut Schmidt, Christina Christoffersen, Uta Ceglarek, Ralph Burkhardt, Jerzy-Roch Nofe. High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. Atherosclerosis. vol 257. 2017-11-01. PMID:28038379. |
high density lipoprotein (hdl)-associated sphingosine 1-phosphate (s1p) inhibits macrophage apoptosis by stimulating stat3 activity and survivin expression. |
2017-11-01 |
2023-08-13 |
Not clear |
| Xing Bao, Tingting Ren, Yi Huang, Kunkun Sun, Shidong Wang, Kuisheng Liu, Bingxin Zheng, Wei Gu. Knockdown of long non-coding RNA HOTAIR increases miR-454-3p by targeting Stat3 and Atg12 to inhibit chondrosarcoma growth. Cell death & disease. vol 8. issue 2. 2017-10-31. PMID:28182000. |
further analysis revealed that stat3 and atg12 are targets of mir-454-3p, initiate hotair deficiency-induced apoptosis and reduce autophagy. |
2017-10-31 |
2023-08-13 |
human |
| Shiyu Song, Zhonglan Su, Hui Xu, Mengyuan Niu, Xiufang Chen, Haiyan Min, Bin Zhang, Guibo Sun, Sijing Xie, Hongwei Wang, Qian Ga. Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1. Cell death & disease. vol 8. issue 2. 2017-10-31. PMID:28182003. |
silencing of shp-1, a protein tyrosine phosphatase, abolished the inhibitory effect of luteolin on stat3 and cell apoptosis, suggesting that shp-1 is crucial in luteolin-mediated cellular function. |
2017-10-31 |
2023-08-13 |
mouse |
| Chun-Yu Liu, Jung-Chen Su, Tzu-Ting Huang, Pei-Yi Chu, Chun-Teng Huang, Wan-Lun Wang, Chia-Han Lee, Ka-Yi Lau, Wen-Chun Tsai, Hsiu-Ping Yang, Chung-Wai Shiau, Ling-Ming Tseng, Kuen-Feng Che. Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells. Molecular oncology. vol 11. issue 3. 2017-10-23. PMID:28084011. |
sc-60 inhibited proliferation and induced apoptosis by dephosphorylating stat3 in both a dose- and time-dependent manner in tnbc cells (mda-mb-231, mda-mb-468, and hcc1937). |
2017-10-23 |
2023-08-13 |
Not clear |
| Chen Feng, Yiqun Xia, Peng Zou, Miaoshan Shen, Jie Hu, Shilong Ying, Jialing Pan, Zhiguo Liu, Xuanxuan Dai, Weishan Zhuge, Guang Liang, Yeping Rua. Curcumin analog L48H37 induces apoptosis through ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human lung cancer cells. Molecular carcinogenesis. vol 56. issue 7. 2017-10-11. PMID:28218464. |
curcumin analog l48h37 induces apoptosis through ros-mediated endoplasmic reticulum stress and stat3 pathways in human lung cancer cells. |
2017-10-11 |
2023-08-13 |
mouse |
| Kristin Bixel, Uksha Saini, Hemant Kumar Bid, John Fowler, Maria Riley, Ross Wanner, Kalpana Deepa Priya Dorayappan, Sneha Rajendran, Ikuo Konishi, Noriomi Matsumura, David E Cohn, Karuppaiyah Selvendira. Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma. International journal of cancer. vol 141. issue 9. 2017-10-09. PMID:28646535. |
targeting stat3 by ho3867 induces apoptosis in ovarian clear cell carcinoma. |
2017-10-09 |
2023-08-13 |
human |
| Yuki Uchihara, Fumihito Ueda, Kenji Tago, Yosuke Nakazawa, Tomoyuki Ohe, Tadahiko Mashino, Shigenobu Yokota, Tadashi Kasahara, Hiroomi Tamura, Megumi Funakoshi-Tag. Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK. PloS one. vol 12. issue 8. 2017-10-09. PMID:28806414. |
the alk inhibitor, crizotinib specifically induced apoptosis in ba/f3 cells expressing npm-alk by inhibiting the activation of npm-alk and its downstream molecule, signal transducer and activator of transcription factor 3 (stat3). |
2017-10-09 |
2023-08-13 |
Not clear |
| Yinli Yang, Bingqing Zheng, Qiuju Han, Cai Zhang, Zhigang Tian, Jian Zhan. Targeting blockage of STAT3 inhibits hepatitis B virus-related hepatocellular carcinoma. Cancer biology & therapy. vol 17. issue 4. 2017-09-27. PMID:26934469. |
the results showed that blocking stat3 signaling by shrnas could promote hbv positive hcc cell apoptosis and induce cell cycle arrest, resulting in hcc cell growth inhibition in vitro. |
2017-09-27 |
2023-08-13 |
mouse |
| Nicole M Jackson, Brian P Ceres. EGFR-mediated apoptosis via STAT3. Experimental cell research. vol 356. issue 1. 2017-09-26. PMID:28433699. |
egfr-mediated apoptosis via stat3. |
2017-09-26 |
2023-08-13 |
Not clear |