| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang He, Huibin Liu, Jing Guo, Di Yang, Yang Yu, Jie Yu, Xiuqing Yan, Juan Hu, Zhimin D. Inhibition of MicroRNA-124 Reduces Cardiomyocyte Apoptosis Following Myocardial Infarction via Targeting STAT3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 51. issue 1. 2018-12-11. PMID:30439699. |
inhibition of microrna-124 reduces cardiomyocyte apoptosis following myocardial infarction via targeting stat3. |
2018-12-11 |
2023-08-13 |
Not clear |
| Nazanin Fathi, Golnaz Rashidi, Ali Khodadadi, Shahriar Shahi, Simin Sharif. STAT3 and apoptosis challenges in cancer. International journal of biological macromolecules. vol 117. 2018-11-16. PMID:29782972. |
stat3 and apoptosis challenges in cancer. |
2018-11-16 |
2023-08-13 |
Not clear |
| Nazanin Fathi, Golnaz Rashidi, Ali Khodadadi, Shahriar Shahi, Simin Sharif. STAT3 and apoptosis challenges in cancer. International journal of biological macromolecules. vol 117. 2018-11-16. PMID:29782972. |
further understanding of the stat3 related signaling and apoptosis pathway can lead to the invention of novel approaches for therapies in unstudied disease. |
2018-11-16 |
2023-08-13 |
Not clear |
| Nazanin Fathi, Golnaz Rashidi, Ali Khodadadi, Shahriar Shahi, Simin Sharif. STAT3 and apoptosis challenges in cancer. International journal of biological macromolecules. vol 117. 2018-11-16. PMID:29782972. |
in this manuscript, review and highlight recent knowledge of the stat3 pathway and its connection with apoptosis process in cancers and discuss stat3-targeting agents to therapeutic developments. |
2018-11-16 |
2023-08-13 |
Not clear |
| Jinshun Xu, Shuai Yuan, Jilai Tian, Kyle A Martin, Jinhua Song, Chenglong Li, Zhigang Wang, Jiayuh Lin, Ting Si, Ronald X X. Ultrasound mediated delivery of oxygen and LLL12 loaded stimuli responsive microdroplets for the treatment of hypoxic cancer cells. Scientific reports. vol 7. 2018-11-14. PMID:28322306. |
lll12 exhibits high specificity for inhibiting stat3 phosphorylation and dimerization, and inducing apoptosis to constitutively activated stat3 cancer cells without cytotoxicity to normal cells with dormant stat3. |
2018-11-14 |
2023-08-13 |
Not clear |
| Duy N Do, Ran Li, Pier-Luc Dudemaine, Eveline M Ibeagha-Awem. MicroRNA roles in signalling during lactation: an insight from differential expression, time course and pathway analyses of deep sequence data. Scientific reports. vol 7. 2018-11-12. PMID:28317898. |
relevant signalling pathways for transition between lactation stages are involved in apoptosis (pten and sapk/jnk), intracellular signalling (protein kinase a, tgf-β and erk5), cell cycle regulation (stat3), cytokines, hormones and growth factors (prolactin, growth hormone and glucocorticoid receptor). |
2018-11-12 |
2023-08-13 |
cattle |
| Flavia M M Paula, Nayara C Leite, Patricia C Borck, Ricardo Freitas-Dias, Miriam Cnop, Mara P T Chacon-Mikahil, Claudia R Cavaglieri, Piero Marchetti, Antonio C Boschero, Claudio C Zoppi, Decio L Eiziri. Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 3. 2018-11-06. PMID:29133342. |
exposure of human islets or mouse or rat β cells to human or rodent sera, respectively, obtained from trained individuals reduced cytokine (il-1β+ifn-γ)- or chemical er stressor-induced β-cell er stress and apoptosis, at least in part via activation of the transcription factor stat3. |
2018-11-06 |
2023-08-13 |
human |
| Jie Gao, Zhongjun Shao, Min Yan, Ting Fu, Lei Zhang, Yongping Ya. Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1. Cancer biomarkers : section A of Disease markers. vol 22. issue 4. 2018-11-05. PMID:29914005. |
cne-1/taxol cells were treated with mir-29a mimic and or si-stat3, followed by measuring the expression of mir-29a, stat3, and p-stat3 and cell apoptosis. |
2018-11-05 |
2023-08-13 |
Not clear |
| Jie Gao, Zhongjun Shao, Min Yan, Ting Fu, Lei Zhang, Yongping Ya. Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1. Cancer biomarkers : section A of Disease markers. vol 22. issue 4. 2018-11-05. PMID:29914005. |
significantly lower rhodamine 123 repository, mir-29a expression and apoptosis and higher expression of stat3, p-stat3 and pcna were observed in cne-2/ taxol cells than those in cne-1 cells. |
2018-11-05 |
2023-08-13 |
Not clear |
| Jie Gao, Zhongjun Shao, Min Yan, Ting Fu, Lei Zhang, Yongping Ya. Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1. Cancer biomarkers : section A of Disease markers. vol 22. issue 4. 2018-11-05. PMID:29914005. |
transfection of mir-29a mimic and/or si-stat3 decreased stat3, p-stat3 and pcna expression, inhibited proliferation and promoted cell apoptosis. |
2018-11-05 |
2023-08-13 |
Not clear |
| Jing Wei, Zhenhua Fan, Zhuo Yang, Yujie Zhou, Fan Da, Linyan Zhou, Wenjing Tao, Deshou Wan. Leukemia Inhibitory Factor Is Essential for the Self-Renewal of Embryonic Stem Cells from Nile Tilapia (Oreochromis niloticus) Through Stat3 Signaling. Stem cells and development. vol 27. issue 2. 2018-11-01. PMID:29161958. |
notably, it mediated stat3 phosphorylation, whose inhibitor treatment could lead to apoptosis. |
2018-11-01 |
2023-08-13 |
mouse |
| Wei Wen, Gina Lowe, Cai M Roberts, James Finlay, Ernest S Han, Carlotta A Glackin, Thanh Hue Dellinge. Pterostilbene Suppresses Ovarian Cancer Growth via Induction of Apoptosis and Blockade of Cell Cycle Progression Involving Inhibition of the STAT3 Pathway. International journal of molecular sciences. vol 19. issue 7. 2018-10-24. PMID:29986501. |
pterostilbene suppresses ovarian cancer growth via induction of apoptosis and blockade of cell cycle progression involving inhibition of the stat3 pathway. |
2018-10-24 |
2023-08-13 |
Not clear |
| Wei Wen, Gina Lowe, Cai M Roberts, James Finlay, Ernest S Han, Carlotta A Glackin, Thanh Hue Dellinge. Pterostilbene Suppresses Ovarian Cancer Growth via Induction of Apoptosis and Blockade of Cell Cycle Progression Involving Inhibition of the STAT3 Pathway. International journal of molecular sciences. vol 19. issue 7. 2018-10-24. PMID:29986501. |
further molecular study has shown that pterostilbene effectively suppressed phosphorylation of stat3, as well as stat3 downstream genes that regulate cell cycle and apoptosis, indicating that inhibition of stat3 pathway may be involved in its anti-tumor activity. |
2018-10-24 |
2023-08-13 |
Not clear |
| Zhibo Dai, Ligang Wang, Xiaoxiong Wang, Boxian Zhao, Wenyang Zhao, Shashank Singh Bhardwaj, Junyi Ye, Zhiqin Yin, Jun Zhang, Shiguang Zha. Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling pathway and STAT3. Oncology reports. vol 40. issue 2. 2018-10-24. PMID:29989652. |
oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the egfr/pi3k/akt/mtor signaling pathway and stat3. |
2018-10-24 |
2023-08-13 |
human |
| Yibin Lin, Jiahui Li, Shazhou Ye, Jiayi Chen, Yanru Zhang, Liu Wang, Yang Xi, Shizhong Bu, Xiaohui Qi. LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells. Gene. vol 678. 2018-10-22. PMID:30098426. |
mechanistically, gacat3 amplified stat3 expression and decreased the level of the apoptosis gene bcl-2-associated x protein (bax). |
2018-10-22 |
2023-08-13 |
Not clear |
| Wei Huang, Yuan Liu, Jun Wang, Xia Yuan, Hong-Wei Jin, Liang-Ren Zhang, Jian-Ting Zhang, Zhen-Ming Liu, Jing-Rong Cu. Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis. European journal of medicinal chemistry. vol 157. 2018-10-22. PMID:30145375. |
small-molecule compounds targeting the stat3 dna-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis. |
2018-10-22 |
2023-08-13 |
human |
| Ling-Qi Meng, Yue Wang, Ying-Hua Luo, Xian-Ji Piao, Chang Liu, Yue Wang, Yi Zhang, Jia-Ru Wang, Hao Wang, Wan-Ting Xu, Yang Liu, Yi-Qin Wu, Hu-Nan Sun, Ying-Hao Han, Mei-Hua Jin, Gui-Nan Shen, Nan-Zhu Fang, Cheng-Hao Ji. Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-16. PMID:29860266. |
quinalizarin induces apoptosis through reactive oxygen species (ros)-mediated mitogen-activated protein kinase (mapk) and signal transducer and activator of transcription 3 (stat3) signaling pathways in colorectal cancer cells. |
2018-10-16 |
2023-08-13 |
Not clear |
| Ling-Qi Meng, Yue Wang, Ying-Hua Luo, Xian-Ji Piao, Chang Liu, Yue Wang, Yi Zhang, Jia-Ru Wang, Hao Wang, Wan-Ting Xu, Yang Liu, Yi-Qin Wu, Hu-Nan Sun, Ying-Hao Han, Mei-Hua Jin, Gui-Nan Shen, Nan-Zhu Fang, Cheng-Hao Ji. Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-16. PMID:29860266. |
quinalizarin induced apoptosis in colorectal cancer cells by regulating mapk and stat3 signaling pathways via ros generation. |
2018-10-16 |
2023-08-13 |
Not clear |
| Xuan Zhang, Silin Zhang, Qitong Sun, Wenjun Jiao, Yan Yan, Xuewu Zhan. Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3. Molecules (Basel, Switzerland). vol 23. issue 6. 2018-10-09. PMID:29921768. |
compound k induces endoplasmic reticulum stress and apoptosis in human liver cancer cells by regulating stat3. |
2018-10-09 |
2023-08-13 |
human |
| Xiqing Li, Zunlan Zhao, Ming Li, Mingyue Liu, Andres Bahena, Yaping Zhang, Yuwei Zhang, Chetan Nambiar, Guangzhi Li. Sulforaphane promotes apoptosis, and inhibits proliferation and self-renewal of nasopharyngeal cancer cells by targeting STAT signal through miRNA-124-3p. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-08. PMID:29677532. |
moreover, sf inhibits proliferation and induces apoptosis decreasing the stemness of nasopharyngeal cancer cells through a mechanism related to stat3 signaling in vitro. |
2018-10-08 |
2023-08-13 |
Not clear |