| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng, Ping Jia. Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells. Cancer cell international. vol 18. 2020-09-29. PMID:29636641. |
down-regulation of stat3 induces the apoptosis and g1 cell cycle arrest in esophageal carcinoma eca109 cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng, Ping Jia. Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells. Cancer cell international. vol 18. 2020-09-29. PMID:29636641. |
to explore the biological role of stat3 in esophageal cancer, we used small hairpin rna to knockdown the expression of the stat3 gene in the esophageal carcinoma eca109 cell line and the cell apoptosis, cell cycle and cell migration were investigated. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jing Li, You-Yu Liu, Xue-Feng Yang, Dao-Fu Shen, Hong-Zhi Sun, Ke-Qiang Huang, Hua-Chuan Zhen. Effects and mechanism of STAT3 silencing on the growth and apoptosis of colorectal cancer cells. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30344711. |
effects and mechanism of stat3 silencing on the growth and apoptosis of colorectal cancer cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jing Li, You-Yu Liu, Xue-Feng Yang, Dao-Fu Shen, Hong-Zhi Sun, Ke-Qiang Huang, Hua-Chuan Zhen. Effects and mechanism of STAT3 silencing on the growth and apoptosis of colorectal cancer cells. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30344711. |
signal transducer and activator of transcription 3 (stat3) have roles in various cellular processes, including angiogenesis, apoptosis, cell cycle progression, cell migration and drug resistance. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jing Li, You-Yu Liu, Xue-Feng Yang, Dao-Fu Shen, Hong-Zhi Sun, Ke-Qiang Huang, Hua-Chuan Zhen. Effects and mechanism of STAT3 silencing on the growth and apoptosis of colorectal cancer cells. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30344711. |
to clarify the effects of stat3 in colorectal cancer (crc) cells and the underlying molecular mechanisms, stat3 was directly silenced, and the effects of stat3 silencing on cell proliferation, apoptosis and growth with phenotype-associated molecules were examined.psh1-si-stat3 was successfully transfected into the crc hct-116 and sw480 cell lines, which was verified by gfp tagging under a fluorescence microscope. |
2020-09-29 |
2023-08-13 |
Not clear |
| Shengxing Wang, Gang Wu, Yinan Han, Peng Song, Jinhuo Chen, Yaoxi Wu, Jie Yang, Peiyu Lian. miR-124 regulates STAT3-mediated cell proliferation, migration and apoptosis in bladder cancer. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30344738. |
knockdown of stat3 expression led to increased apoptosis of t24 cells and reduced tumor growth |
2020-09-29 |
2023-08-13 |
Not clear |
| Xin Lu, Jun Qia. Downregulated MEG3 participates in rheumatoid arthritis via promoting proliferation of fibroblast-like synoviocytes. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783431. |
downregulated meg3 was able to promote proliferation and invasion, and inhibit apoptosis of fls via stat3 pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xiao-Yan Lei, Xing-Xing Chen, Yong-Hong Sun, Ming-Dong Gao, Xiao-Xia Hu, Yan-Hong Su. Hepatitis B virus X protein decreases nephrin expression and induces podocyte apoptosis via activating STAT3. Experimental and therapeutic medicine. vol 17. issue 5. 2020-09-29. PMID:31007753. |
hepatitis b virus x protein decreases nephrin expression and induces podocyte apoptosis via activating stat3. |
2020-09-29 |
2023-08-13 |
Not clear |
| Moli Wu, Danyang Song, Hui Li, Yang Yang, Xiaodong Ma, Sa Deng, Changle Ren, Xiaohong Sh. Negative regulators of STAT3 signaling pathway in cancers. Cancer management and research. vol 11. 2020-09-29. PMID:31213912. |
stat3 is the most ubiquitous member of the stat family and involved in many biological processes, such as cell proliferation, differentiation, and apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Qiongtao Song, Ying Zhao, Qiang Li, Xue Han, Junguo Dua. Puerarin protects against iron overload-induced retinal injury through regulation of iron-handling proteins. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 122. 2020-09-29. PMID:31786468. |
moreover, puerarin inhibited the phosphorylation of p38 and erk mitogen-activated protein kinases (mapks) and signal transducer and activator of transcription 3 (stat3), thereby protecting the retinal cells from apoptosis by suppressing cytochrome c release, caspase activation, and poly (adp-ribose) polymerase cleavage in vivo. |
2020-09-29 |
2023-08-13 |
mouse |
| Ningning He, Changyan Xiao, Yuxiao Sun, Yan Wang, Liqing Du, Yu Feng, Yang Liu, Qin Wang, Kaihua Ji, Jinhan Wang, Manman Zhang, Chang Xu, Qiang Li. Radiation Responses of Human Mesenchymal Stem Cells Derived From Different Sources. Dose-response : a publication of International Hormesis Society. vol 17. issue 4. 2020-09-29. PMID:31839760. |
in our study, a comparison of the results from cell proliferation, apoptosis, cell cycle, dna damage, and dna repair assays consistently showed that mscs derived from adipose tissue possess a significantly stronger radiation resistance capacity than mscs derived from umbilical cord and gingival, which is accompanied by a higher level of phosphorylated signal transducer and activator of transcription 3 (stat3) expression. |
2020-09-29 |
2023-08-13 |
human |
| Yi Xu, Yanyue Tong, Junjie Ying, Zhangming Lei, Lijun Wan, Xiuwen Zhu, Feng Ye, Penglei Mao, Xinkuan Wu, Renbing Pan, Bo Peng, Yukun Liu, Jianyong Zh. Chrysin induces cell growth arrest, apoptosis, and ER stress and inhibits the activation of STAT3 through the generation of ROS in bladder cancer cells. Oncology letters. vol 15. issue 6. 2020-09-28. PMID:29805643. |
chrysin induces cell growth arrest, apoptosis, and er stress and inhibits the activation of stat3 through the generation of ros in bladder cancer cells. |
2020-09-28 |
2023-08-13 |
Not clear |
| Joo Young Hong, Kyung-Sook Chung, Ji-Sun Shin, Jeong-Hun Lee, Hyo-Sun Gil, Hwi-Ho Lee, Eunwoo Choi, Jung-Hye Choi, Ahmed H E Hassan, Yong Sup Lee, Kyung-Tae Le. The Anti-Proliferative Activity of the Hybrid TMS-TMF-4f Compound Against Human Cervical Cancer Involves Apoptosis Mediated by STAT3 Inactivation. Cancers. vol 11. issue 12. 2020-09-28. PMID:31816985. |
the anti-proliferative activity of the hybrid tms-tmf-4f compound against human cervical cancer involves apoptosis mediated by stat3 inactivation. |
2020-09-28 |
2023-08-13 |
human |
| Filippo Severin, Federica Frezzato, Andrea Visentin, Veronica Martini, Valentina Trimarco, Samuela Carraro, Elena Tibaldi, Anna Maria Brunati, Francesco Piazza, Gianpietro Semenzato, Monica Facco, Livio Trenti. In Chronic Lymphocytic Leukemia the JAK2/STAT3 Pathway Is Constitutively Activated and Its Inhibition Leads to CLL Cell Death Unaffected by the Protective Bone Marrow Microenvironment. Cancers. vol 11. issue 12. 2020-09-28. PMID:31817171. |
treatment with ag490, but not stattic, caused stat3 and lyn dephosphorylation, through re-activation of shp-1, and triggered cll apoptosis even when leukemic cells were cultured on bmsc layers. |
2020-09-28 |
2023-08-13 |
Not clear |
| Muhammad Zubair Saleem, Muhammad Azhar Nisar, Mohammed Alshwmi, Syed Riaz Ud Din, Yaser Gamallat, Muhammad Khan, Tonghui M. Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells. OncoTargets and therapy. vol 13. 2020-09-28. PMID:32021288. |
brevilin a inhibits stat3 signaling and induces ros-dependent apoptosis, mitochondrial stress and endoplasmic reticulum stress in mcf-7 breast cancer cells. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xin Li, Xin Wang, Yuan-Sheng Liu, Xiao-Dong Wang, Jian Zhou, Hua Zho. Downregulation of miR-3568 Protects Against Ischemia/Reperfusion-Induced Cardiac Dysfunction in Rats and Apoptosis in H9C2 Cardiomyocytes Through Targeting TRIM62. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32116696. |
mir-3568 mimic transfection in h9c2 cardiomyocytes significantly enhanced cell apoptosis, decreased the expression of bcl-2 and survivin, and activated stat3 signaling, which were reversed by mir-3568 inhibitor. |
2020-09-28 |
2023-08-13 |
rat |
| Xin Li, Xin Wang, Yuan-Sheng Liu, Xiao-Dong Wang, Jian Zhou, Hua Zho. Downregulation of miR-3568 Protects Against Ischemia/Reperfusion-Induced Cardiac Dysfunction in Rats and Apoptosis in H9C2 Cardiomyocytes Through Targeting TRIM62. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32116696. |
trim62 overexpression or ag490, a selective inhibitor of jak2/stat3 significantly, significantly inhibited i/r and mir-3568 mimic induced cell apoptosis and stat3 activation. |
2020-09-28 |
2023-08-13 |
rat |
| Jeong-Hun Lee, Hwi-Ho Lee, Ki Deok Ryu, Misong Kim, Dohyeong Ko, Kyung-Sook Chung, Ahmed H E Hassan, Seung Hyeun Lee, Jae Yeol Lee, Kyung-Tae Le. KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation. Journal of clinical medicine. vol 9. issue 3. 2020-09-28. PMID:32150979. |
kcp10043f represses the proliferation of human non-small cell lung cancer cells by caspase-mediated apoptosis via stat3 inactivation. |
2020-09-28 |
2023-08-13 |
human |
| Zhangmei Chang, Yan Wang, Xin Zhou, Jian-Er Lon. STAT3 roles in viral infection: antiviral or proviral? Future virology. vol 13. issue 8. 2020-09-28. PMID:32201498. |
an activated stat3 translocates into the nucleus and combines with dna to regulate the expression of target genes involved in cell proliferation, differentiation, apoptosis and metastasis. |
2020-09-28 |
2023-08-13 |
human |
| Carla Pereira, Daniel Ferreira, Nuno Mendes, Pedro L Granja, Gabriela M Almeida, Carla Oliveir. Expression of CD44v6-Containing Isoforms Influences Cisplatin Response in Gastric Cancer Cells. Cancers. vol 12. issue 4. 2020-09-28. PMID:32252293. |
upon cisplatin treatment, cd44v6+ cells survive better and have lower apoptosis levels than cd44v6- cells, possibly due to concomitant activation of stat3 and p38. |
2020-09-28 |
2023-08-13 |
Not clear |