Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Li-Ping Lin, Qian Zhang, Wei Wu, Yan Xue, Yong-Jin Tang, Dong-Hong Li. [Effect of MiR-29b-3p Targeting STAT3 on Proliferation and Apoptosis of Acute Myeloid Leukemia Cells]. Zhongguo shi yan xue ye xue za zhi. vol 28. issue 6. 2020-12-08. PMID:33283710. |
[effect of mir-29b-3p targeting stat3 on proliferation and apoptosis of acute myeloid leukemia cells]. |
2020-12-08 |
2023-08-13 |
Not clear |
Li-Ping Lin, Qian Zhang, Wei Wu, Yan Xue, Yong-Jin Tang, Dong-Hong Li. [Effect of MiR-29b-3p Targeting STAT3 on Proliferation and Apoptosis of Acute Myeloid Leukemia Cells]. Zhongguo shi yan xue ye xue za zhi. vol 28. issue 6. 2020-12-08. PMID:33283710. |
to investigate the effect of mir-29b-3p on apoptosis and proliferation of acute myeloid leukemia (aml) cells by targeting signal transducer and activator of transcription 3 (stat3). |
2020-12-08 |
2023-08-13 |
Not clear |
W-D Wu, L-H Wang, N-X Wei, D-H Kong, G Shao, S-R Zhang, Y-S D. MicroRNA-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting STAT3. European review for medical and pharmacological sciences. vol 23. issue 21. 2020-12-07. PMID:31773669. |
microrna-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting stat3. |
2020-12-07 |
2023-08-13 |
Not clear |
Soo Kyung Park, Woong Sub Byun, Seungbeom Lee, Young Taek Han, Yoo-Seong Jeong, Kyungkuk Jang, Suk-Jae Chung, Jeeyeon Lee, Young-Ger Suh, Sang Kook Le. A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction. Biochemical pharmacology. vol 178. 2020-12-07. PMID:32450253. |
furthermore, slsi-1216 induced apoptosis by targeting stat3 and effectively inhibited tumor growth in vivo. |
2020-12-07 |
2023-08-13 |
human |
Yun-Jing Hou, Xin-Xin Yang, Rui-Qi Liu, Di Zhao, Chen-Xu Guo, An-Chao Zhu, Mei-Na Wen, Zhao Liu, Guo-Fan Qu, Hong-Xue Men. Pathological Mechanism of Photodynamic Therapy and Photothermal Therapy Based on Nanoparticles. International journal of nanomedicine. vol 15. 2020-12-07. PMID:32982235. |
in this paper, the mechanism of pathological treatment is described in detail in terms of inducing apoptosis of cancer cells by ros produced by pdt, immunogenic cell death to provoke the maturation of dendritic cells, which in turn activate production of cd4+ t cells, cd8+t cells and memory t cells, as well as inhibiting heat shock protein (hsps), stat3 signal pathway and so on. |
2020-12-07 |
2023-08-13 |
Not clear |
Kaiyan Wang, Zhenhua Liu, Meina Zhao, Fuyang Zhang, Kai Wang, Na Feng, Feng Fu, Jun Li, Juan Li, Yali Liu, Shumiao Zhang, Rong Fan, Haitao Guo, Jianming Pe. κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway. European journal of pharmacology. vol 874. 2020-12-01. PMID:32032598. |
furthermore, inhibition of stat3 phosphorylation by stattic, a specific stat3 inhibitor, repressed the effects of κ-opioid receptor activation on promoting opa1 expression and mitochondrial fusion, as well as inhibiting cell apoptosis and oxidative stress both in vivo and in vitro during mi/r injury. |
2020-12-01 |
2023-08-13 |
mouse |
Qin Chen, Ming Wang, Chengji She. Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32005795. |
bauerane induces s-phase cell cycle arrest, apoptosis, and inhibition of proliferation of a549 human lung cancer cells through the phosphoinositide 3-kinase (pi3k)/akt and signal transducer and activator of transcription 3 (stat3) signaling pathway. |
2020-11-24 |
2023-08-13 |
human |
Sruthi V Hindupur, Sebastian C Schmid, Jana Annika Koch, Ahmed Youssef, Eva-Maria Baur, Dongbiao Wang, Thomas Horn, Julia Slotta-Huspenina, Juergen E Gschwend, Per Sonne Holm, Roman Nawrot. STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy. International journal of molecular sciences. vol 21. issue 3. 2020-11-18. PMID:32046095. |
treatment with stat3/5 but not jak1/2 inhibitors reduced survival, levels of phosphorylated stat3 and cyclin-d1 and increased apoptosis. |
2020-11-18 |
2023-08-13 |
chicken |
Yuchen Gu, Yingying Huang, Yiming Sun, Xin Liang, Lingti Kong, Zhe Liu, Lulu Wan. [Long non-coding RNA LINC01106 regulates colorectal cancer cell proliferation and apoptosis through the STAT3 pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 40. issue 9. 2020-11-18. PMID:32990221. |
[long non-coding rna linc01106 regulates colorectal cancer cell proliferation and apoptosis through the stat3 pathway]. |
2020-11-18 |
2023-08-13 |
Not clear |
Guangjie Zhan, Jun Hu, Benjian Xiao, Xianli Wang, Zixian Yang, Guohua Yang, Lili L. Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells. Medical oncology (Northwood, London, England). vol 37. issue 5. 2020-11-12. PMID:32270306. |
trillin prevents proliferation and induces apoptosis through inhibiting stat3 nuclear translocation in hepatoma carcinoma cells. |
2020-11-12 |
2023-08-13 |
Not clear |
Guangjie Zhan, Jun Hu, Benjian Xiao, Xianli Wang, Zixian Yang, Guohua Yang, Lili L. Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells. Medical oncology (Northwood, London, England). vol 37. issue 5. 2020-11-12. PMID:32270306. |
this study demonstrated that trillin could dramatically inhibit hepatoma carcinoma cell proliferation, induce apoptosis and decrease migration and invasion through suppressing phosphorylated stat3 translocated to nucleus. |
2020-11-12 |
2023-08-13 |
Not clear |
Jae Young So, Nicolas Skrypek, Howard H Yang, Anand S Merchant, George W Nelson, Wei-Dong Chen, Hiroki Ishii, Jennifer M Chen, Gangqing Hu, Bhagelu R Achyut, Esther C Yoon, Liying Han, Chuanshu Huang, Margaret C Cam, Keji Zhao, Maxwell P Lee, Li Yan. Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization. Cancer research. vol 80. issue 12. 2020-11-06. PMID:32265226. |
multiomics analysis and spontaneous metastatic mouse models revealed that dnmt3b alters multiple pathways including stat3, nfκb, pi3k/akt, β-catenin, and notch signaling, which are critical for cancer cell survival, apoptosis, proliferation, invasion, and colonization. |
2020-11-06 |
2023-08-13 |
mouse |
Kyung-Ran Park, Hyung-Mun Yun, Jin Tae Hon. G721-0282 inhibits cell growth and induces apoptosis in human osteosarcoma through down-regulation of the STAT3 pathway. International journal of biological sciences. vol 16. issue 2. 2020-11-02. PMID:31929760. |
g721-0282 inhibits cell growth and induces apoptosis in human osteosarcoma through down-regulation of the stat3 pathway. |
2020-11-02 |
2023-08-13 |
human |
Di Chen, Yangmin Ma, Zhiyu Guo, Li Liu, Yaru Yang, Yuru Wang, Bonan Pan, Luyang Wu, Yuyu Hui, Wenjuan Yan. Two Natural Alkaloids Synergistically Induce Apoptosis in Breast Cancer Cells by Inhibiting STAT3 Activation. Molecules (Basel, Switzerland). vol 25. issue 1. 2020-11-02. PMID:31948057. |
two natural alkaloids synergistically induce apoptosis in breast cancer cells by inhibiting stat3 activation. |
2020-11-02 |
2023-08-13 |
Not clear |
Di Chen, Yangmin Ma, Zhiyu Guo, Li Liu, Yaru Yang, Yuru Wang, Bonan Pan, Luyang Wu, Yuyu Hui, Wenjuan Yan. Two Natural Alkaloids Synergistically Induce Apoptosis in Breast Cancer Cells by Inhibiting STAT3 Activation. Molecules (Basel, Switzerland). vol 25. issue 1. 2020-11-02. PMID:31948057. |
furthermore, apoptosis and stat3 signaling pathway-associated protein levels were analyzed. |
2020-11-02 |
2023-08-13 |
Not clear |
Di Chen, Yangmin Ma, Zhiyu Guo, Li Liu, Yaru Yang, Yuru Wang, Bonan Pan, Luyang Wu, Yuyu Hui, Wenjuan Yan. Two Natural Alkaloids Synergistically Induce Apoptosis in Breast Cancer Cells by Inhibiting STAT3 Activation. Molecules (Basel, Switzerland). vol 25. issue 1. 2020-11-02. PMID:31948057. |
we demonstrated that pp and pl in combination inhibit stat3 phosphorylation and regulate downstream molecules to induce apoptosis in breast cancer cells. |
2020-11-02 |
2023-08-13 |
Not clear |
Pengfei Li, Huina Lv, Min Xu, Bin Zang, Yegang M. ARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway. Cancer management and research. vol 12. 2020-10-30. PMID:33116826. |
arhgap6 promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through stat3 signaling pathway. |
2020-10-30 |
2023-08-13 |
Not clear |
Juan Tornin, Miguel Mateu-Sanz, Aida Rodríguez, Cédric Labay, Rene Rodríguez, Cristina Cana. Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma. Scientific reports. vol 9. issue 1. 2020-10-23. PMID:31337843. |
os cells show higher sensitivity to pam treatment than healthy cells, both in medium with and without pyruvate, activating apoptosis, dna damage and deregulating cellular pathways mediated by c-jun, akt, ampk or stat3. |
2020-10-23 |
2023-08-13 |
Not clear |
Mahdieh Safaei, Hadi Maleki, Hamidreza Soleimanpour, Amir Norouzy, Hossein Shahbani Zahiri, Hojatollah Vali, Kambiz Akbari Noghab. Development of a novel method for the purification of C-phycocyanin pigment from a local cyanobacterial strain Limnothrix sp. NS01 and evaluation of its anticancer properties. Scientific reports. vol 9. issue 1. 2020-10-13. PMID:31263160. |
the reduced expression levels of anti-apoptotic proteins, bcl2 and stat3, plus cell cycle regulator protein, cyclin d1, using real-time pcr confirm that the c-pc-induced death of mcf-7 human breast cancer cells occurred through the mitochondrial pathway of apoptosis. |
2020-10-13 |
2023-08-13 |
human |
M-H Li, Z-Y Wu, Y Wang, F-Z Chen, Y Li. Expression of miR-29 and STAT3 in osteosarcoma and its effect on proliferation regulation of osteosarcoma cells. European review for medical and pharmacological sciences. vol 23. issue 17. 2020-10-06. PMID:31539114. |
this study investigated whether mir-29 regulates the stat3 expression and affects the proliferation and apoptosis of osteosarcoma cells. |
2020-10-06 |
2023-08-13 |
Not clear |