| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donatella D'Eliseo, Livia Di Renzo, Angela Santoni, Francesca Velott. Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells. Genes & cancer. vol 8. issue 1-2. 2021-01-03. PMID:28435516. |
stat3 pathway, essential for mm survival, contributed to cancer cell apoptosis by dha. |
2021-01-03 |
2023-08-13 |
human |
| Xiuyun Lv, Lihong Wang, Tianji Zh. MiR-20a-5p suppressed TGF-β1-triggered apoptosis of human bronchial epithelial BEAS-2B cells by targeting STAT3. Molecular and cellular probes. vol 50. 2020-12-30. PMID:31883454. |
mir-20a-5p suppressed tgf-β1-triggered apoptosis of human bronchial epithelial beas-2b cells by targeting stat3. |
2020-12-30 |
2023-08-13 |
human |
| Mahnaz Mohammadi Kian, Mahdieh Salemi, Mohammad Bahadoran, Atousa Haghi, Nasrin Dashti, Saeed Mohammadi, Shahrbano Rostami, Bahram Chahardouli, Davood Babakhani, Mohsen Nikbakh. Curcumin Combined with Thalidomide Reduces Expression of Drug design, development and therapy. vol 14. 2020-12-22. PMID:32021103. |
the aim of this study was to evaluate the effect of curcumin (cur) and thalidomide (thal) on apoptosis induction and also the alteration of the mrna expression level of stat3 and bcl-xl mrna on aml cell line compounds. |
2020-12-22 |
2023-08-13 |
human |
| Hua Fang, Fang-Xiang Zhang, Hua-Feng Li, Miao Yang, Ren Liao, Ru-Rong Wang, Quan-Yun Wang, Peng-Cheng Zheng, Jian-Ping Zhan. PRR34-AS1 overexpression promotes protection of propofol pretreatment against ischemia/reperfusion injury in a mouse model after total knee arthroplasty via blockade of the JAK1-dependent JAK-STAT signaling pathway. Journal of cellular physiology. vol 235. issue 3. 2020-12-17. PMID:31556112. |
upregulated prr34-as1 diminished expression of jak1, stat1, jak2, and stat3 as well as cell apoptosis, while enhancing cell proliferation in vitro. |
2020-12-17 |
2023-08-13 |
mouse |
| Tohid Gharibi, Zohreh Babaloo, Arezoo Hosseini, Meghdad Abdollahpour-Alitappeh, Vida Hashemi, Faroogh Marofi, Kazem Nejati, Behzad Baradara. Targeting STAT3 in cancer and autoimmune diseases. European journal of pharmacology. vol 878. 2020-12-17. PMID:32278856. |
stat3 is the key regulator of cell proliferation, survival and apoptosis and is constitutively activated in most human cancers, indicating that it can be an important potential therapeutic target for cancer treatment. |
2020-12-17 |
2023-08-13 |
human |
| Linbao Wen, Jingwei Sun, Xionggao Chen, Ruili D. miR-135b-dependent downregulation of S100B promotes neural stem cell differentiation in a hypoxia/ischemia-induced cerebral palsy rat model. American journal of physiology. Cell physiology. vol 319. issue 6. 2020-12-15. PMID:32491925. |
s100b downregulation targeted by mir-135b overexpression contributed to the inactivation of the signal transducer and activator of transcription-3 (stat3) pathway, which promoted nsc differentiation and proliferation but inhibited nsc apoptosis. |
2020-12-15 |
2023-08-13 |
rat |
| Hong-Tao Song, Yuan Cui, Li-Li Zhang, Guang Cao, Lin Li, Gang Li, Xin-Ju Ji. Ruxolitinib attenuates intimal hyperplasia via inhibiting JAK2/STAT3 signaling pathway activation induced by PDGF-BB in vascular smooth muscle cells. Microvascular research. vol 132. 2020-12-15. PMID:32818511. |
ruxolitinib, a potent janus kinase (jak) 1 and 2 inhibitor, has been reported to significantly block the proliferation-related signaling pathway of jak2/signal transducers and activators of transcription 3 (stat3) and harbor a broad spectrum of anti-cancer activities, including proliferation inhibition, apoptosis induction, and anti-inflammation. |
2020-12-15 |
2023-08-13 |
Not clear |
| Radhika Saraf, Aniruddha Datta, Chao Sima, Jianping Hua, Rosana Lopes, Michael L Bittner, Tasha Miller, Heather M Wilson-Roble. In silico modeling of the induction of apoptosis by Cryptotanshinone in osteosarcoma cell lines. IEEE/ACM transactions on computational biology and bioinformatics. vol PP. 2020-12-15. PMID:33180729. |
we show that the action of the herbal drug, cryptotanshinone on os cell lines induces apoptosis by increasing sensitivity to tnf-related apoptosis-inducing ligand (trail) through its multi-pronged action on stat3, drp1 and dr5. |
2020-12-15 |
2023-08-13 |
Not clear |
| I Gkouveris, N Nikitakis, A Sklavouno. p38 Expression and Modulation of STAT3 Signaling in Oral Cancer. Pathology oncology research : POR. vol 26. issue 1. 2020-12-11. PMID:29564744. |
persistent activation of stat3 has been associated with cell proliferation, differentiation and apoptosis in oral squamous cell carcinoma (oscc). |
2020-12-11 |
2023-08-13 |
Not clear |
| Zhu-Xia Jia, Xu-Zhang Lu, Jin-Yuan He, Xiao-Hui Cai, Wei Qin, Wen-Min Han, Min Zhou, Wei X. [Mechanism of Anti Apoptosis and Immune Evasion in Drug-Resistant Leukemia Cells Mediated by STAT3]. Zhongguo shi yan xue ye xue za zhi. vol 28. issue 6. 2020-12-08. PMID:33283701. |
[mechanism of anti apoptosis and immune evasion in drug-resistant leukemia cells mediated by stat3]. |
2020-12-08 |
2023-08-13 |
Not clear |
| Li-Ping Lin, Qian Zhang, Wei Wu, Yan Xue, Yong-Jin Tang, Dong-Hong Li. [Effect of MiR-29b-3p Targeting STAT3 on Proliferation and Apoptosis of Acute Myeloid Leukemia Cells]. Zhongguo shi yan xue ye xue za zhi. vol 28. issue 6. 2020-12-08. PMID:33283710. |
[effect of mir-29b-3p targeting stat3 on proliferation and apoptosis of acute myeloid leukemia cells]. |
2020-12-08 |
2023-08-13 |
Not clear |
| Li-Ping Lin, Qian Zhang, Wei Wu, Yan Xue, Yong-Jin Tang, Dong-Hong Li. [Effect of MiR-29b-3p Targeting STAT3 on Proliferation and Apoptosis of Acute Myeloid Leukemia Cells]. Zhongguo shi yan xue ye xue za zhi. vol 28. issue 6. 2020-12-08. PMID:33283710. |
to investigate the effect of mir-29b-3p on apoptosis and proliferation of acute myeloid leukemia (aml) cells by targeting signal transducer and activator of transcription 3 (stat3). |
2020-12-08 |
2023-08-13 |
Not clear |
| W-D Wu, L-H Wang, N-X Wei, D-H Kong, G Shao, S-R Zhang, Y-S D. MicroRNA-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting STAT3. European review for medical and pharmacological sciences. vol 23. issue 21. 2020-12-07. PMID:31773669. |
microrna-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting stat3. |
2020-12-07 |
2023-08-13 |
Not clear |
| Soo Kyung Park, Woong Sub Byun, Seungbeom Lee, Young Taek Han, Yoo-Seong Jeong, Kyungkuk Jang, Suk-Jae Chung, Jeeyeon Lee, Young-Ger Suh, Sang Kook Le. A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction. Biochemical pharmacology. vol 178. 2020-12-07. PMID:32450253. |
furthermore, slsi-1216 induced apoptosis by targeting stat3 and effectively inhibited tumor growth in vivo. |
2020-12-07 |
2023-08-13 |
human |
| Yun-Jing Hou, Xin-Xin Yang, Rui-Qi Liu, Di Zhao, Chen-Xu Guo, An-Chao Zhu, Mei-Na Wen, Zhao Liu, Guo-Fan Qu, Hong-Xue Men. Pathological Mechanism of Photodynamic Therapy and Photothermal Therapy Based on Nanoparticles. International journal of nanomedicine. vol 15. 2020-12-07. PMID:32982235. |
in this paper, the mechanism of pathological treatment is described in detail in terms of inducing apoptosis of cancer cells by ros produced by pdt, immunogenic cell death to provoke the maturation of dendritic cells, which in turn activate production of cd4+ t cells, cd8+t cells and memory t cells, as well as inhibiting heat shock protein (hsps), stat3 signal pathway and so on. |
2020-12-07 |
2023-08-13 |
Not clear |
| Kaiyan Wang, Zhenhua Liu, Meina Zhao, Fuyang Zhang, Kai Wang, Na Feng, Feng Fu, Jun Li, Juan Li, Yali Liu, Shumiao Zhang, Rong Fan, Haitao Guo, Jianming Pe. κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway. European journal of pharmacology. vol 874. 2020-12-01. PMID:32032598. |
furthermore, inhibition of stat3 phosphorylation by stattic, a specific stat3 inhibitor, repressed the effects of κ-opioid receptor activation on promoting opa1 expression and mitochondrial fusion, as well as inhibiting cell apoptosis and oxidative stress both in vivo and in vitro during mi/r injury. |
2020-12-01 |
2023-08-13 |
mouse |
| Qin Chen, Ming Wang, Chengji She. Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32005795. |
bauerane induces s-phase cell cycle arrest, apoptosis, and inhibition of proliferation of a549 human lung cancer cells through the phosphoinositide 3-kinase (pi3k)/akt and signal transducer and activator of transcription 3 (stat3) signaling pathway. |
2020-11-24 |
2023-08-13 |
human |
| Sruthi V Hindupur, Sebastian C Schmid, Jana Annika Koch, Ahmed Youssef, Eva-Maria Baur, Dongbiao Wang, Thomas Horn, Julia Slotta-Huspenina, Juergen E Gschwend, Per Sonne Holm, Roman Nawrot. STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy. International journal of molecular sciences. vol 21. issue 3. 2020-11-18. PMID:32046095. |
treatment with stat3/5 but not jak1/2 inhibitors reduced survival, levels of phosphorylated stat3 and cyclin-d1 and increased apoptosis. |
2020-11-18 |
2023-08-13 |
chicken |
| Yuchen Gu, Yingying Huang, Yiming Sun, Xin Liang, Lingti Kong, Zhe Liu, Lulu Wan. [Long non-coding RNA LINC01106 regulates colorectal cancer cell proliferation and apoptosis through the STAT3 pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 40. issue 9. 2020-11-18. PMID:32990221. |
[long non-coding rna linc01106 regulates colorectal cancer cell proliferation and apoptosis through the stat3 pathway]. |
2020-11-18 |
2023-08-13 |
Not clear |
| Guangjie Zhan, Jun Hu, Benjian Xiao, Xianli Wang, Zixian Yang, Guohua Yang, Lili L. Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells. Medical oncology (Northwood, London, England). vol 37. issue 5. 2020-11-12. PMID:32270306. |
trillin prevents proliferation and induces apoptosis through inhibiting stat3 nuclear translocation in hepatoma carcinoma cells. |
2020-11-12 |
2023-08-13 |
Not clear |