| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenqi Huang, Hang Sun, Ting Hu, Dongju Zhu, Xianli Long, Hui Guo, Qi Li. Blocking the short isoform of augmenter of liver regeneration inhibits proliferation of human multiple myeloma U266 cells via the MAPK/STAT3/cell cycle signaling pathway. Oncology letters. vol 21. issue 3. 2021-02-13. PMID:33574936. |
the present findings suggested that blocking extracellular 15-kda-alr in u266 cells with an anti-alr mcab decreased cell proliferation via the mapk, stat3 and cell cycle signaling pathways without increasing apoptosis. |
2021-02-13 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
long non-coding rna ak093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via stat3 activation. |
2021-02-12 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
lastly, we showed that stat3 activation was essential for the effects of ak093407 on cell proliferation and apoptosis as the overexpression of ak093407 in the presence of stat3 inhibitor did not promote cell proliferation and inhibit cell apoptosis. |
2021-02-12 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
ak093407 is highly expressed in osteosarcoma cells and tissues, and promotes cell proliferation and viability and inhibits apoptosis of osteosarcoma cell line u-2os via stat3 activation. |
2021-02-12 |
2023-08-13 |
human |
| Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation [Retraction]. American journal of cancer research. vol 11. issue 2. 2021-02-12. PMID:33575092. |
long non-coding rna ak093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via stat3 activation [retraction]. |
2021-02-12 |
2023-08-13 |
human |
| Vikram Shaw, Suyash Srivastava, Sanjay K Srivastav. Repurposing antipsychotics of the diphenylbutylpiperidine class for cancer therapy. Seminars in cancer biology. vol 68. 2021-02-10. PMID:31618686. |
antipsychotic drugs induce apoptosis and suppress metastasis in in vitro and in vivo models through mechanisms involving p53, stat3, stat5, protein phosphatase 2a, cholesterol homeostasis, integrins, autophagy, usp1, wnt/β-catenin signaling, and dna repair. |
2021-02-10 |
2023-08-13 |
Not clear |
| Chenming Wang, Shaozheng Chen, Xiuying Yu. Gammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and STAT3 signaling pathway. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 25. issue 2. 2021-02-08. PMID:32521859. |
gammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and stat3 signaling pathway. |
2021-02-08 |
2023-08-13 |
human |
| Yifan Xie, Xiaotao Li, Junbo G. STAT3-CyPA signaling pathway in endothelial cell apoptosis. Cellular signalling. vol 65. 2021-02-05. PMID:31494257. |
moreover, with cell viability and apoptosis assays, we identified stat3 stimulated cypa-dependent apoptosis of human umbilical vein ecs in vitro. |
2021-02-05 |
2023-08-13 |
human |
| Hailun Zheng, Zhiwei Chen, Aimin Cai, Xinlu Lin, Xinyu Jiang, Bin Zhou, Jun Wang, Qing Yao, Ruijie Chen, Longfa Ko. Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition. Colloids and surfaces. B, Biointerfaces. vol 193. 2021-02-03. PMID:32416521. |
mechanism studies showed that dnnps significantly induced mitochondrial-dependent apoptosis and inhibited stat3 phosphorylation, explaining the enhanced anticancer effect. |
2021-02-03 |
2023-08-13 |
Not clear |
| Hailun Zheng, Zhiwei Chen, Aimin Cai, Xinlu Lin, Xinyu Jiang, Bin Zhou, Jun Wang, Qing Yao, Ruijie Chen, Longfa Ko. Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition. Colloids and surfaces. B, Biointerfaces. vol 193. 2021-02-03. PMID:32416521. |
these results suggested that dnnps represented a promising strategy against gastric cancer by inhibiting the stat3 pathway and amplifying apoptosis. |
2021-02-03 |
2023-08-13 |
Not clear |
| Afshin Nikkhoo, Narges Rostami, Shohreh Farhadi, Maryam Esmaily, Sadaf Moghadaszadeh Ardebili, Fatemeh Atyabi, Masoumeh Baghaei, Navideh Haghnavaz, Mehdi Yousefi, Mohammad Reza Aliparasti, Ghasem Ghalamfarsa, Hamed Mohammadi, Mozhdeh Sojoodi, Farhad Jadidi-Niarag. Codelivery of STAT3 siRNA and BV6 by carboxymethyl dextran trimethyl chitosan nanoparticles suppresses cancer cell progression. International journal of pharmaceutics. vol 581. 2021-02-01. PMID:32240809. |
use of bv6, a well-known iap inhibitor, along with inhibition of signal transducer and activator of transcription 3 (stat3), which is an important factor in the survival of tumor cells, and nik as a mediator of bv6 unpredicted side effects, can induce effective apoptosis in tumor cells. |
2021-02-01 |
2023-08-13 |
Not clear |
| Renba Lian. Letter to the editor Re: Pan et al. "LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer". Breast cancer research and treatment. vol 184. issue 2. 2021-02-01. PMID:32803634. |
"lly17, a novel small molecule stat3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer". |
2021-02-01 |
2023-08-13 |
Not clear |
| Yan-Qing Zang, Yu-Qing Zhai, Yan-Yu Feng, Xue-Ying Ju, Feng Zu. Molecular mechanisms of quinalizarin induces apoptosis and G0/G1 cell cycle of human esophageal cancer HCE-4 cells depends on MAPK, STAT3, and NF-κB signaling pathways. Environmental toxicology. vol 36. issue 2. 2021-01-25. PMID:33030807. |
molecular mechanisms of quinalizarin induces apoptosis and g0/g1 cell cycle of human esophageal cancer hce-4 cells depends on mapk, stat3, and nf-κb signaling pathways. |
2021-01-25 |
2023-08-13 |
human |
| Yan-Qing Zang, Yu-Qing Zhai, Yan-Yu Feng, Xue-Ying Ju, Feng Zu. Molecular mechanisms of quinalizarin induces apoptosis and G0/G1 cell cycle of human esophageal cancer HCE-4 cells depends on MAPK, STAT3, and NF-κB signaling pathways. Environmental toxicology. vol 36. issue 2. 2021-01-25. PMID:33030807. |
the pretreatment of n-acetyl-l-cysteine (nac) blocked the apoptosis induced by quina and inhibited the activities of mapk, stat3, and nf-κb signaling pathways. |
2021-01-25 |
2023-08-13 |
human |
| Yan-Qing Zang, Yu-Qing Zhai, Yan-Yu Feng, Xue-Ying Ju, Feng Zu. Molecular mechanisms of quinalizarin induces apoptosis and G0/G1 cell cycle of human esophageal cancer HCE-4 cells depends on MAPK, STAT3, and NF-κB signaling pathways. Environmental toxicology. vol 36. issue 2. 2021-01-25. PMID:33030807. |
these results indicate that quina induces the apoptosis in hce-4 cells, which is via accumulating ros generation and regulating mapk, stat3, and nf-κb. |
2021-01-25 |
2023-08-13 |
human |
| Yin Cai, Fan Ying, Hao Liu, Liang Ge, Erfei Song, Lin Wang, Dengwen Zhang, Eva Hoi Ching Tang, Zhengyuan Xia, Michael G Irwi. Deletion of Rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of STAT3 signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 3. 2021-01-21. PMID:32020680. |
deletion of rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of stat3 signaling. |
2021-01-21 |
2023-08-13 |
mouse |
| Yin Cai, Fan Ying, Hao Liu, Liang Ge, Erfei Song, Lin Wang, Dengwen Zhang, Eva Hoi Ching Tang, Zhengyuan Xia, Michael G Irwi. Deletion of Rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of STAT3 signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 3. 2021-01-21. PMID:32020680. |
in h9c2 and primary cardiomyocytes, rap1 knockdown or knockout significantly suppressed hypoxia/reoxygenation (h/r)-induced cell injury and apoptosis through increasing the phosphorylation/activation of stat3 at site ser |
2021-01-21 |
2023-08-13 |
mouse |
| Si-Yuan Jing, Zi-Dan Wu, Tie-Hua Zhang, Jie Zhang, Zheng-Yi We. In vitro antitumor effect of cucurbitacin E on human lung cancer cell line and its molecular mechanism. Chinese journal of natural medicines. vol 18. issue 7. 2021-01-20. PMID:32616188. |
the activated transcription factor stat3 and the apoptosis inhibitor protein survivin were also observed to be reduced. |
2021-01-20 |
2023-08-13 |
human |
| Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Lu. MicroRNA-140-5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3. Experimental and therapeutic medicine. vol 21. issue 2. 2021-01-19. PMID:33456538. |
microrna-140-5p regulates the proliferation, apoptosis and inflammation of ra flss by repressing stat3. |
2021-01-19 |
2023-08-13 |
Not clear |
| Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Lu. MicroRNA-140-5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3. Experimental and therapeutic medicine. vol 21. issue 2. 2021-01-19. PMID:33456538. |
notably, restoration of stat3 expression rescued the regulatory effect of mir-140 on the proliferation, apoptosis and inflammatory cytokine production of ra flss. |
2021-01-19 |
2023-08-13 |
Not clear |