| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiaoyu Wang, Qiongjun Zhu, Qiaofang Ye, Jiajun Wang, Qianqian Dong, Youran Chen, Minna Wang, Yu Fu, Rongzhou Wu, Tingting W. STAT3 Suppresses Cardiomyocytes Apoptosis in CVB3-Induced Myocarditis Via Survivin. Frontiers in pharmacology. vol 11. 2021-03-05. PMID:33658937. |
stat3 suppresses cardiomyocytes apoptosis in cvb3-induced myocarditis via survivin. |
2021-03-05 |
2023-08-13 |
Not clear |
| Silke D Werle, Julian D Schwab, Marina Tatura, Sandra Kirchhoff, Robin Szekely, Ramona Diels, Nensi Ikonomi, Bence Sipos, Jan Sperveslage, Thomas M Gress, Malte Buchholz, Hans A Kestle. Unraveling the Molecular Tumor-Promoting Regulation of Cofilin-1 in Pancreatic Cancer. Cancers. vol 13. issue 4. 2021-03-03. PMID:33578795. |
moreover, we could predict that cfl1 impacts proliferation and apoptosis via the signal transducer and activator of transcription 3 (stat3). |
2021-03-03 |
2023-08-13 |
human |
| Sha Yang, Xiaoning Wang, Cancan Duan, Jianyong Zhan. A novel approach combining metabolomics and molecular pharmacology to study the effect of Gei Herba on mouse hematopoietic function. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32768939. |
lbz activates pi3k/akt signaling pathways and granulocyte-colony-stimulating-factor (g-csf)-mediated janus kinase 2 (jak2)/transcription 3 (stat3), resulting in inhibiting the release of cytochrome c. further, lbz inhibits caspase-mediated mitochondrial-dependent apoptosis mediated by caspase-9 and caspase-3. |
2021-02-26 |
2023-08-13 |
mouse |
| Sepideh Mirzaei, Mohammad Hossein Gholami, Mahmood Khaksary Mahabady, Noushin Nabavi, Amirhossein Zabolian, Seyed Mohammad Banihashemi, Amirabbas Haddadi, Maliheh Entezari, Kiavash Hushmandi, Pooyan Makvandi, Saeed Samarghandian, Ali Zarrabi, Milad Ashrafizadeh, Haroon Kha. Pre-clinical investigation of STAT3 pathway in bladder cancer: Paving the way for clinical translation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33378975. |
in respect to its tumor-promoting role, stat3 is able to enhance the growth of bc cells via inhibiting apoptosis and cell cycle arrest. |
2021-02-24 |
2023-08-13 |
Not clear |
| Chun-Chia Cheng, Bi-Ling Yang, Wen-Chao Chen, Ai-Sheng Ho, Zong-Lin Sie, Hsin-Chi Lin, Chun-Chao Chan. STAT3 Mediated miR-30a-5p Inhibition Enhances Proliferation and Inhibits Apoptosis in Colorectal Cancer Cells. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33023006. |
stat3 mediated mir-30a-5p inhibition enhances proliferation and inhibits apoptosis in colorectal cancer cells. |
2021-02-23 |
2023-08-13 |
Not clear |
| Xue Li, Yuquan Wei, Xiawei We. Napabucasin, a novel inhibitor of STAT3, inhibits growth and synergises with doxorubicin in diffuse large B-cell lymphoma. Cancer letters. vol 491. 2021-02-22. PMID:32798587. |
mechanistic studies demonstrated that napabucasin induced intrinsic and extrinsic cell apoptosis, downregulated the expression of stat3 target genes, including the antiapoptotic protein mcl-1, and regulated the ros-mediated mitogen-activated protein kinase (mapk) pathway. |
2021-02-22 |
2023-08-13 |
Not clear |
| Xiaoxu Ma, Kai Wu, Aiguo Xu, Pengfei Jiao, Huiling Li, Lihua Xin. The sesquiterpene lactone eupatolide induces apoptosis in non-small cell lung cancer cells by suppressing STAT3 signaling. Environmental toxicology and pharmacology. vol 81. 2021-02-22. PMID:33091599. |
the sesquiterpene lactone eupatolide induces apoptosis in non-small cell lung cancer cells by suppressing stat3 signaling. |
2021-02-22 |
2023-08-13 |
mouse |
| Xiaoxu Ma, Kai Wu, Aiguo Xu, Pengfei Jiao, Huiling Li, Lihua Xin. The sesquiterpene lactone eupatolide induces apoptosis in non-small cell lung cancer cells by suppressing STAT3 signaling. Environmental toxicology and pharmacology. vol 81. 2021-02-22. PMID:33091599. |
furthermore, eupatolide induced apoptosis by suppressing the activation of stat3 in nsclc cells. |
2021-02-22 |
2023-08-13 |
mouse |
| Yuan Liang, Tiehua Zhang, Li Ren, Siyuan Jing, Zhuolin Li, Peng Zuo, Tiezhu Li, Yongjun Wang, Jie Zhang, Zhengyi We. Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. Environmental toxicology and pharmacology. vol 81. 2021-02-22. PMID:33161110. |
cuiib induced apoptosis via stat3 pathway, which was mitochondria-mediated and caspase-dependent. |
2021-02-22 |
2023-08-13 |
Not clear |
| Jeremy J McGuire, Jeremy S Frieling, Chen Hao Lo, Tao Li, Ayaz Muhammad, Harshani R Lawrence, Nicholas J Lawrence, Leah M Cook, Conor C Lync. Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer. Nature communications. vol 12. issue 1. 2021-02-19. PMID:33526787. |
acquired resistance to apoptosis is pca cell intrinsic, and is associated with a shift in il-28rα signaling via stat1 to stat3. |
2021-02-19 |
2023-08-13 |
Not clear |
| Wenqi Huang, Hang Sun, Ting Hu, Dongju Zhu, Xianli Long, Hui Guo, Qi Li. Blocking the short isoform of augmenter of liver regeneration inhibits proliferation of human multiple myeloma U266 cells via the MAPK/STAT3/cell cycle signaling pathway. Oncology letters. vol 21. issue 3. 2021-02-13. PMID:33574936. |
the present findings suggested that blocking extracellular 15-kda-alr in u266 cells with an anti-alr mcab decreased cell proliferation via the mapk, stat3 and cell cycle signaling pathways without increasing apoptosis. |
2021-02-13 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
long non-coding rna ak093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via stat3 activation. |
2021-02-12 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
lastly, we showed that stat3 activation was essential for the effects of ak093407 on cell proliferation and apoptosis as the overexpression of ak093407 in the presence of stat3 inhibitor did not promote cell proliferation and inhibit cell apoptosis. |
2021-02-12 |
2023-08-13 |
human |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
ak093407 is highly expressed in osteosarcoma cells and tissues, and promotes cell proliferation and viability and inhibits apoptosis of osteosarcoma cell line u-2os via stat3 activation. |
2021-02-12 |
2023-08-13 |
human |
| Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation [Retraction]. American journal of cancer research. vol 11. issue 2. 2021-02-12. PMID:33575092. |
long non-coding rna ak093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via stat3 activation [retraction]. |
2021-02-12 |
2023-08-13 |
human |
| Vikram Shaw, Suyash Srivastava, Sanjay K Srivastav. Repurposing antipsychotics of the diphenylbutylpiperidine class for cancer therapy. Seminars in cancer biology. vol 68. 2021-02-10. PMID:31618686. |
antipsychotic drugs induce apoptosis and suppress metastasis in in vitro and in vivo models through mechanisms involving p53, stat3, stat5, protein phosphatase 2a, cholesterol homeostasis, integrins, autophagy, usp1, wnt/β-catenin signaling, and dna repair. |
2021-02-10 |
2023-08-13 |
Not clear |
| Chenming Wang, Shaozheng Chen, Xiuying Yu. Gammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and STAT3 signaling pathway. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 25. issue 2. 2021-02-08. PMID:32521859. |
gammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and stat3 signaling pathway. |
2021-02-08 |
2023-08-13 |
human |
| Yifan Xie, Xiaotao Li, Junbo G. STAT3-CyPA signaling pathway in endothelial cell apoptosis. Cellular signalling. vol 65. 2021-02-05. PMID:31494257. |
moreover, with cell viability and apoptosis assays, we identified stat3 stimulated cypa-dependent apoptosis of human umbilical vein ecs in vitro. |
2021-02-05 |
2023-08-13 |
human |
| Hailun Zheng, Zhiwei Chen, Aimin Cai, Xinlu Lin, Xinyu Jiang, Bin Zhou, Jun Wang, Qing Yao, Ruijie Chen, Longfa Ko. Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition. Colloids and surfaces. B, Biointerfaces. vol 193. 2021-02-03. PMID:32416521. |
mechanism studies showed that dnnps significantly induced mitochondrial-dependent apoptosis and inhibited stat3 phosphorylation, explaining the enhanced anticancer effect. |
2021-02-03 |
2023-08-13 |
Not clear |
| Hailun Zheng, Zhiwei Chen, Aimin Cai, Xinlu Lin, Xinyu Jiang, Bin Zhou, Jun Wang, Qing Yao, Ruijie Chen, Longfa Ko. Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition. Colloids and surfaces. B, Biointerfaces. vol 193. 2021-02-03. PMID:32416521. |
these results suggested that dnnps represented a promising strategy against gastric cancer by inhibiting the stat3 pathway and amplifying apoptosis. |
2021-02-03 |
2023-08-13 |
Not clear |