| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiunan Yu, Xiaohong L. microRNA-1906 protects cerebral ischemic injury through activating Janus kinase 2/signal transducer and activator of transcription 3 pathway in rats. Neuroreport. vol 31. issue 12. 2021-08-13. PMID:32427806. |
after treating with jak2/stat3 pathway inhibitor ag490, the phosphorylation of jak2 and stat3 was inhibited and the effects of mir-1906 on neurological score, infarct volume, brain water content, neuronal apoptosis and inflammatory factors were reversed. |
2021-08-13 |
2023-08-13 |
rat |
| Li-Bin Gao, Xin-Le Zhu, Jing-Xian Shi, Ling Yang, Zhen-Qiang Xu, Song-Lin Sh. HnRNPA2B1 promotes the proliferation of breast cancer MCF-7 cells via the STAT3 pathway. Journal of cellular biochemistry. vol 122. issue 3-4. 2021-08-12. PMID:33399232. |
collectively, our results demonstrate that hnrnpa2/b1 promotes tumor cell growth in vitro and in vivo by activating the stat3 pathway, regulating apoptosis and autophagy. |
2021-08-12 |
2023-08-13 |
mouse |
| Chen Sun, Ming Bai, Weiwei Ke, Xiaoxun Wang, Xiangxuan Zhao, Zaiming L. The HSP90 inhibitor, XL888, enhanced cell apoptosis via downregulating STAT3 after insufficient radiofrequency ablation in hepatocellular carcinoma. Life sciences. vol 282. 2021-08-12. PMID:34186047. |
the hsp90 inhibitor, xl888, enhanced cell apoptosis via downregulating stat3 after insufficient radiofrequency ablation in hepatocellular carcinoma. |
2021-08-12 |
2023-08-13 |
Not clear |
| Aikai Zhang, Fenfang Yu, Wande Yu, Peng Ye, Pengfei Liu, Yue Gu, Shaoliang Chen, Hang Zhan. Pyruvate kinase M2 activation protects against the proliferation and migration of pulmonary artery smooth muscle cells. Cell and tissue research. vol 382. issue 3. 2021-08-10. PMID:32719938. |
pkm2 phosphorylation promoted the dimerization activation and nuclear translocation of stat3, a transcription factor regulating proliferation, growth, and apoptosis. |
2021-08-10 |
2023-08-13 |
mouse |
| Jing Li, Yubing Wang, Lisha Li, Penelope M-Y Or, Chi Wai Wong, Tian Liu, Wayne L H Ho, Andrew M Cha. Tumour-derived substrate-adherent cells promote neuroblastoma survival through secreted trophic factors. Molecular oncology. vol 15. issue 8. 2021-08-10. PMID:33932101. |
overall, the tumour-derived s-type cells prevented apoptosis in the n-type cells via alk-independent stat3 activation triggered by secreted factors. |
2021-08-10 |
2023-08-13 |
Not clear |
| Rong-Rong Li, De-Yu Zen. The effects and mechanism of α-mangostin on chemosensitivity of gastric cancer cells. The Kaohsiung journal of medical sciences. vol 37. issue 8. 2021-08-10. PMID:34003591. |
cell proliferation and apoptosis were assessed as well as the levels of ebi3, stat3, p-stat3, autophagy-related proteins, and apoptosis-related proteins. |
2021-08-10 |
2023-08-13 |
Not clear |
| Liang Li, Minbiao Chen, Gao Li, Renzhong Ca. Raddeanin A induced apoptosis of non-small cell lung cancer cells by promoting ROS-mediated STAT3 inactivation. Tissue & cell. vol 71. 2021-08-09. PMID:34146943. |
raddeanin a induced apoptosis of non-small cell lung cancer cells by promoting ros-mediated stat3 inactivation. |
2021-08-09 |
2023-08-13 |
Not clear |
| Ping Cui, Fen Wei, Jingjing Hou, Ying Su, Jijun Wang, Sicen Wan. STAT3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial STAT3 translocation and respiratory chain dysfunction. Cellular signalling. vol 71. 2021-08-05. PMID:32165236. |
stat3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial stat3 translocation and respiratory chain dysfunction. |
2021-08-05 |
2023-08-13 |
Not clear |
| Ping Cui, Fen Wei, Jingjing Hou, Ying Su, Jijun Wang, Sicen Wan. STAT3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial STAT3 translocation and respiratory chain dysfunction. Cellular signalling. vol 71. 2021-08-05. PMID:32165236. |
in the present study, we demonstrated that the salicylic acid-based compound sh-4-54 was quite toxic to temozolomide (tmz)-resistant gbm cells and could trigger apoptosis in these cells via enhancing mitochondrial translocation-dependent non-canonical stat3 pathway. |
2021-08-05 |
2023-08-13 |
Not clear |
| Chenglong Chen, Hongliang Zhang, Yiyang Yu, Qingshan Huang, Wei Wang, Jianfang Niu, Jingbing Lou, Tingting Ren, Yi Huang, Wei Gu. Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3. Aging. vol 13. issue 13. 2021-08-04. PMID:34170850. |
chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of stat3. |
2021-08-04 |
2023-08-13 |
Not clear |
| Shibin Zhang, Tingting Meng, Chunzhi Tang, Shengdong Li, Xudong Cai, Dawei Wang, Min Che. MicroRNA-340-5p suppressed rheumatoid arthritis synovial fibroblast proliferation and induces apoptotic cell number by targeting signal transducers and activators of transcription 3. Autoimmunity. vol 53. issue 6. 2021-07-26. PMID:32706318. |
overexpression of stat3 could reverse the outcome of microrna-340-5p on cell proliferation and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes. |
2021-07-26 |
2023-08-13 |
human |
| Nana Xu, Jingnuan Hu, Ke Han, Yang Ou, Tingting Ji, Jialiang Xin. Shionone suppresses the growth, migration and invasion of human breast cancer cells via induction of apoptosis and inhibition of MEK/ERK and STAT3 signalling pathways. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 25. issue 4. 2021-07-22. PMID:33099919. |
shionone suppresses the growth, migration and invasion of human breast cancer cells via induction of apoptosis and inhibition of mek/erk and stat3 signalling pathways. |
2021-07-22 |
2023-08-13 |
human |
| Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Y. STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway. Infection and immunity. vol 89. issue 3. 2021-07-22. PMID:33257536. |
stat3 promotes schistosome-induced liver injury by inflammation, oxidative stress, proliferation, and apoptosis signal pathway. |
2021-07-22 |
2023-08-13 |
mouse |
| Lijuan Chen, Zhi Guo, Yongming Zhou, Jian Ni, Jianhua Zhu, Xu Fan, Xuexing Chen, Yiling Liu, Ziping Li, Hao Zho. microRNA-1246-containing extracellular vesicles from acute myeloid leukemia cells promote the survival of leukemia stem cells via the LRIG1-meditated STAT3 pathway. Aging. vol 13. issue 10. 2021-07-22. PMID:33893245. |
mir-1246 inhibitor or ev-encapsulated mir-1246 inhibitor was found to suppress the viability and colony formation abilities but promoted the apoptosis and differentiation of lscs through inactivation of stat3 pathway by up-regulating lrig1. |
2021-07-22 |
2023-08-13 |
Not clear |
| Matthew B Minus, Haopei Wang, Jaime O Munoz, Alexandra M Stevens, Alicia E Mangubat-Medina, Michael J Krueger, Wei Liu, Moses M Kasembeli, Julian C Cooper, Mikhail I Kolosov, David J Tweardy, Michele S Redell, Zachary T Bal. Targeting STAT3 anti-apoptosis pathways with organic and hybrid organic-inorganic inhibitors. Organic & biomolecular chemistry. vol 18. issue 17. 2021-07-21. PMID:32286579. |
this paper describes synthetic studies and biological assays for a naphthalene sulfonamide inhibitor class of molecules that inhibit g-csf-induced stat3 phosphorylation in cellulo and induce apoptosis in aml cells. |
2021-07-21 |
2023-08-13 |
Not clear |
| Miao Mo, Yangle Li, Xiheng H. Serum CXCL5 level is associated with tumor progression in penile cancer. Bioscience reports. vol 41. issue 1. 2021-07-21. PMID:33458757. |
furthermore, knockdown of cxcl5 or cxcr2 expression markedly suppressed malignant phenotypes (cell proliferation, clonogenesis, apoptosis escape, migration, and invasion), attenuated stat3 and akt signaling, and reduced mmp2/9 secretion in pc cell lines. |
2021-07-21 |
2023-08-13 |
Not clear |
| Jiankuo Guo, Dongmei Dou, Tianlun Zhang, Bo Wan. HOTAIR Promotes Cisplatin Resistance of Osteosarcoma Cells by Regulating Cell Proliferation, Invasion, and Apoptosis via miR-106a-5p/STAT3 Axis. Cell transplantation. vol 29. 2021-07-19. PMID:32757663. |
what's more, the transfection of stat3 sirna reversed the decrease of ddp resistance, cell proliferation, and invasion and rescued the increase of apoptosis induced by mir-106a-5p inhibition. |
2021-07-19 |
2023-08-13 |
Not clear |
| Xiaodong Sun, Qianqian Xu, Lian Zeng, Lixia Xie, Qiang Zhao, Hongxia Xu, Xuanbin Wang, Nan Jiang, Pan Fu, Ming San. Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3 Cancer medicine. vol 9. issue 22. 2021-07-19. PMID:33040485. |
resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting stat3 aberrant signal transducer and activator of transcription 3 (stat3) signaling promotes the initiation and progression of cancer in humans by either inhibiting apoptosis or inducing cell proliferation, angiogenesis, invasion, and metastasis. |
2021-07-19 |
2023-08-13 |
mouse |
| Dongjun Jiang, Jiaqi Xu, Sitong Liu, Moussa Ide Nasser, Wei Wei, Tianjiao Mao, Xintong Liu, Xiaopan Zou, Jiang Li, Xiaomeng L. Rosmanol induces breast cancer cells apoptosis by regulating PI3K/AKT and STAT3/JAK2 signaling pathways. Oncology letters. vol 22. issue 2. 2021-07-17. PMID:34267823. |
moreover, rosmanol inhibited proliferation and promoted apoptosis of cancer cells via the inhibition of erk and stat3 signals, attributable to the increase in p-p38, the overexpression of protein inhibitor of activated stat3, and the decrease in pi3k/akt, erk and jak2/stat3. |
2021-07-17 |
2023-08-13 |
human |
| Fengyun Zhou, Ting Feng, Xiangqi Lu, Huicheng Wang, Yangping Chen, Qiuxia Zhang, Xinlu Zhang, Jiancheng Xi. Interleukin 35 protects cardiomyocytes following ischemia/reperfusion-induced apoptosis via activation of mitochondrial STAT3. Acta biochimica et biophysica Sinica. vol 53. issue 4. 2021-07-16. PMID:33619515. |
interleukin 35 protects cardiomyocytes following ischemia/reperfusion-induced apoptosis via activation of mitochondrial stat3. |
2021-07-16 |
2023-08-13 |
mouse |